Infectious Diseases

2019 ◽  
Author(s):  
Doug Fink
Keyword(s):  
Infectious Diseases ◽  
Modern Medicine ◽  
Emerging Infections ◽  
High Resource ◽  
The World ◽  
Causes Of Mortality ◽  
And Migration ◽  
Almost All ◽  
Global And Local ◽  
Immunomodulatory Therapies

Infectious diseases are global and local. They impact health and dis­ease in every country, but protean factors— cultural, geographical, and political— determine their particular local distribution. Every single patient is globally colonized by microorganisms, but singular behaviours, genetics and co- morbidities significantly determine what organisms cause disease in any individual. The practice of infectious diseases medi­cine necessarily demands an understanding of the person and the world in which they live. This chapter will emphasize the importance of context in assessing patients for infectious diseases. In terms of global mortality, communicable diseases remain the leading causes of mortality. Despite the evocative epithet of ‘infectious diseases’, these are not all caused by creatures that creep and crawl. Cosmopolitan diseases (i.e. universally distributed infections such as influenza or bac­terial pneumonia) represent a huge burden wherever medicine is prac­tised. However, it is important to note that in high- resource settings, infection imported by travel and migration is increasing. In particular, the international traffic of emerging infections, such as Zika virus, and anti-microbial resistance (AMR) are already major healthcare problems. As the world shrinks and the climate changes, the distribution of infectious diseases will continue to change. The threat of AMR no longer looms— it is a present and real danger. In the time it will take for disciples of this text to reach the end of their specialty training, AMR will account annually for more deaths than cancer. The delivery of almost all interventional, surgical, and immunomodulatory therapies depends on our ability to provide effective anti- microbial prophylaxis and rescue. The ability of organisms to adapt rapidly to novel iatrogenic selection pressures means that the treatment of human immunodeficiency virus (HIV), tuberculosis (TB), malaria, and manifold other pathogens will be compromised, not simply anti- bacterial agents. The future of modern medicine depends on the global healthcare community sharing both concern and responsibility. This chapter will include cases pertaining to the management of AMR.

1+1 > 2: Integration of the Host-directed Traditional Chinese Medicine and the Virus-targeted Modern Medicine in Control of COVID-19

2020 ◽  
Vol 7 (2) ◽  
pp. 89-94
Author(s):  
Jianjun Sun
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Infectious Diseases ◽  
Modern Medicine ◽  
The World ◽  
Plausible Mechanism

The COVID-19 pandemic has caused millions of infections and hundreds of thousands deaths in the world. The pandemic is still ongoing and no specific antivirals have been found to control COVID-19. The integration of Traditional Chinese Medicine with supportive measures of Modern Medicine has reportedly played an important role in the control of COVID-19 in China. This review summarizes the evidence of TCM in the treatment of COVID-19 and discusses the plausible mechanism of TCM in control of COVID-19 and other viral infectious diseases.

scholarly journals Qualitative Research: Institutional Preparedness During Threats of Infectious Disease Outbreaks

2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Doret de Rooij ◽  
Evelien Belfroid ◽  
Renske Eilers ◽  
Dorothee Roßkamp ◽  
Corien Swaan ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Focus Group ◽  
Infectious Diseases ◽  
Group Discussion ◽  
Disease Outbreaks ◽  
Care Staff ◽  
Infectious Disease Outbreaks ◽  
High Resource ◽  
The World ◽  
Centralized Care

Background. As demonstrated during the global Ebola crisis of 2014–2016, healthcare institutions in high resource settings need support concerning preparedness during threats of infectious disease outbreaks. This study aimed to exploratively develop a standardized preparedness system to use during unfolding threats of severe infectious diseases. Methods. A qualitative three-step study among infectious disease prevention and control experts was performed. First, interviews (n=5) were conducted to identify which factors trigger preparedness activities during an unfolding threat. Second, these triggers informed the design of a phased preparedness system which was tested in a focus group discussion (n=11). Here preparedness activities per phase and per healthcare institution were identified. Third, the preparedness system was completed and verified in individual interviews (n=3). Interviews and the focus group were recorded, transcribed, and coded for emerging themes by two researchers independently. Data were analyzed using content analysis. Results. Four preparedness phases were identified: preparedness phase green is a situation without the presence of the infectious disease threat that requires centralized care, anywhere in the world. Phase yellow is an outbreak in the world with some likelihood of imported cases. Phase orange is a realistic chance of an unexpected case within the country, or unrest developing among population or staff; phase red is cases admitted to hospitals in the country, potentially causing a shortage of resources. Specific preparedness activities included infection prevention, diagnostics, patient care, staff, and communication. Consensus was reached on the need for the development of a preparedness system and national coordination during threats. Conclusions. In this study, we developed a standardized system to support institutional preparedness during an increasing threat. Use of this system by both curative healthcare institutions and the (municipal) public health service, could help to effectively communicate and align preparedness activities during future threats of severe infectious diseases.

scholarly journals Ivermectin the Promising Drug to Stave off the COVID-19 Crisis: A Review

2021 ◽  
Vol 7 (2) ◽  
pp. 95-98
Author(s):  
Zakia Jahan ◽  
Masudul Hassan
Keyword(s):  
Infectious Diseases ◽  
Specific Treatment ◽  
In Vitro Study ◽  
Antiviral Effect ◽  
Viral Particles ◽  
The World ◽  
Infected Cells ◽  
Almost All ◽  
First Time

The Coronavirus disease 2019 (COVID-19) outbreak, forcing us to face unprecedented moments in the world. The huge devastating impact of the world due to the covid-19 attack causes the brink of no return. However, there is no proven and specific treatment for Covid -19. Very few medications have received Emergency Use of Authorization. A recent in vitro study was the first time to find out and to assess the antiviral effect of Ivermectin on COVID-19. The study showed that Ivermectin was active against COVID- 19-infected cells, was able to kill effectively almost all viral particles within 48 h. In these moments of crisis, FDA-approved ivermectin is a ray of hope. Bangladesh Journal of Infectious Diseases 2020;7(2):95-98

scholarly journals THE CHYTRID BLINDERS 2.0: HOW ARE WE DOING?

2021 ◽  
Author(s):  
Amanda Duffus
Keyword(s):  
Population Dynamics ◽  
Environmental Factors ◽  
Infectious Diseases ◽  
Habitat Destruction ◽  
Emerging Infections ◽  
Amphibian Population ◽  
Amphibian Disease ◽  
The Past ◽  
The World ◽  
Pathogenic Agents

Amphibians are declining around the world and infectious diseases are thought to play a key role in these declines, along with habitat destruction and other environmental factors.  Since the late 1900s, several emerging infections have been identified in amphibians. The chytrids, of which there are two known to affect amphibians, Batrachochytrium dendtrobatids, and B. salamandrivorans; and ranaviruses are perhaps the most well-known and studied. There are also other, lesser known and studied pathogenic agents such as Perkinsea spp. and herpesviruses; that have emerged in approximately the same timeline, which may also be contributing to amphibian population dynamics. In this piece we examine the progress that has been made over the past decade in understanding ‘The Big Three’ and specifically how the emergence of B. salamandrivorans has brought together much of the amphibian disease world in the last half of the 2010s.

scholarly journals Communicable diseases common to man and animals – current state of the problem

2019 ◽  
pp. 36-45
Author(s):  
I. Subbotina ◽  
I. Andamov ◽  
B. Bakyev ◽  
I. Kuprijanov ◽  
Safar-zadeh Hamid Rafi k ogly
Keyword(s):  
Infectious Diseases ◽  
Key Words ◽  
Molecular Genetic ◽  
Zoonotic Diseases ◽  
Human Medicine ◽  
Current State ◽  
Comparative Aspect ◽  
The World ◽  
The Republic ◽  
Almost All

Оne of the signifi cant problems for the veterinary service and for human medicine workers around the world are infectious diseases (parasitic and infectious), common to humans and animals. In most countries, this group of diseases is called “zoonoses,” although in many countries and many researchers this term raises many questions and disagreements. In a number of countries, it is customary to strictly divide them into “zooanthroponoses” and “anthropozoonoses”. However, despite the diff erence in terminology, the importance of zoonotic diseases remains relevant for everyone. Of course, in countries with diff erent climatic, geographical, cultural and gastronomic characteristics, certain diseases will prevail, but their social and economic signifi cance, however, will be similar for everyone. In our work, we wanted in a comparative aspect to show the most signifi cant zoonoses and the dependence of their distribution on climatic, geographical, gastronomic, cultural and a number of other features of the countries. We have carried out work in such countries as the Republic of Belarus, Turkmenistan, Tajikistan and Azerbaijan. In our work, we identifi ed the most signifi cant zoonoses for the above countries and determined the main causes and factors contributing to the emergence and dissemination of these pathologies The studies were carried out using modern research methods, such as epizootological, virological, bacteriological, molecular genetic, statistical. As a result of the studies, it was found that a number of zoonotic diseases, such as rabies, pasteurellosis, tuberculosis, are quite widespread in almost all of these countries, while anthrax, brucellosis, echinococcosis, have a signifi cant diff erence in the intensity of spread, and the immediate causes of this diff erence are both climatic and geographical factors, and features of agriculture, and a number of others. Key words: zoonoses, infections, infestations, rabies, pasteurellosis, anthrax, brucellosis, tuberculosis, echinococcosis, cestodoses, trichinosis, ascariasis, cryptosporidiosis.

scholarly journals Essential facts about Covid-19: the disease, the responses, and an uncertain future. For South African learners, teachers, and the general public

2021 ◽  
Author(s):  
Keyword(s):  
South Africa ◽  
Infectious Diseases ◽  
Modern Medicine ◽  
Childhood Mortality ◽  
Modern World ◽  
Quality Healthcare ◽  
School Year ◽  
Almost Everywhere ◽  
The World ◽  
The Impact

The first cases of a new coronavirus (SARS-CoV-2) were identified toward the end of 2019 in Wuhan, China. Over the following months, this virus spread to everywhere in the world. By now no country has been spared the devastation from the loss of lives from the disease (Covid-19) and the economic and social impacts of responses to mitigate the impact of the virus. Our lives in South Africa have been turned upside down as we try to make the best of this bad situation. The 2020 school year was disrupted with closure and then reopening in a phased approach, as stipulated by the Department of Education. This booklet is a collective effort by academics who are Members of the Academy of Science of South Africa (ASSAf) and other invited scholars to help you appreciate some of the basic scientific facts that you need to know in order to understand the present crisis and the various options available to respond to it. We emphasise that the threat of infectious diseases is not an entirely new phenomenon that has sprung onto the stage out of nowhere. Infectious diseases and pandemics have been with us for centuries, in fact much longer. Scientists have warned us for years of the need to prepare for the next pandemic. Progress in medicine in the course of the 20th century has been formidable. Childhood mortality has greatly decreased almost everywhere in the world, thanks mainly, but not only, to the many vaccines that have been developed. Effective drugs now exist for many deadly diseases for which there were once no cures. For many of us, this progress has generated a false sense of security. It has caused us to believe that the likes of the 1918 ‘Spanish flu’ pandemic, which caused some 50 million deaths around the world within a span of a few months, could not be repeated in some form in today’s modern world. The Covid-19 pandemic reminds us that as new cures for old diseases are discovered, new diseases come along for which we are unprepared. And every hundred or so years one of these diseases wreaks havoc on the world and interferes severely with our usual ways of going about our lives. Today’s world has become increasingly interconnected and interdependent, through trade, migrations, and rapid air travel. This globalisation makes it easier for epidemics to spread, somewhat offsetting the power of modern medicine. In this booklet we have endeavoured to provide an historical perspective, and to enrich your knowledge with some of the basics of medicine, viruses, and epidemiology. Beyond the immediate Covid-19 crisis, South Africa faces a number of other major health challenges: highly unequal access to quality healthcare, widespread tuberculosis, HIV infection causing AIDS, a high prevalence of mental illness, and a low life expectancy, compared to what is possible with today’s medicine. It is essential that you, as young people, also learn about the nature of these new challenges, so that you may contribute to finding future solutions.

Infectious diseases and prions

2021 ◽  
pp. 163-186
Author(s):  
Davidson H. Hamer ◽  
Amira Khan ◽  
Zulfiqar A. Bhutta
Keyword(s):  
Antimicrobial Resistance ◽  
Infectious Diseases ◽  
Respiratory Infections ◽  
Scale Up ◽  
Emerging Infections ◽  
Middle Income ◽  
Middle Income Countries ◽  
Disease Mortality ◽  
Causes Of Mortality ◽  
Parasitic Pathogens

Infectious diseases continue to contribute considerably to the global burden of morbidity, disability, and mortality, especially in low- and middle-income countries. Lower respiratory infections, diarrhoea, and tuberculosis remain among the top ten causes of mortality for all ages and sexes. Moreover, the emergence of many new viral, bacterial, fungal, and parasitic pathogens as well as rising antimicrobial resistance are current challenges. Despite a decline in infectious disease mortality, the growing dangers of antimicrobial resistance and emerging infections pose a critical threat to the health of millions. It is imperative, now more than ever, to scale up interventions for prevention and control of infectious diseases while promoting judicious use of antimicrobials.

Globalization and interconfessional communications

2001 ◽  
pp. 13-17
Author(s):  
Serhii Viktorovych Svystunov
Keyword(s):  
21St Century ◽  
Global Economy ◽  
Modern World ◽  
The World ◽  
Target Set ◽  
Almost All ◽  
Over Time ◽  
Rapid Appearance

In the 21st century, the world became a sign of globalization: global conflicts, global disasters, global economy, global Internet, etc. The Polish researcher Casimir Zhigulsky defines globalization as a kind of process, that is, the target set of characteristic changes that develop over time and occur in the modern world. These changes in general are reduced to mutual rapprochement, reduction of distances, the rapid appearance of a large number of different connections, contacts, exchanges, and to increase the dependence of society in almost all spheres of his life from what is happening in other, often very remote regions of the world.

From the Tower of London to the Thomas More Society of Buenos Aires: “Give me thy grace, good Lord, to set the world at nought”

Moreana ◽  
2005 ◽  
Vol 42 (Number 164) (4) ◽  
pp. 187-206
Author(s):  
Clare M. Murphy
Keyword(s):  
Buenos Aires ◽  
Short History ◽  
Thomas More ◽  
Tower Of London ◽  
Hebrew Poetry ◽  
Prayer Book ◽  
The World ◽  
History Of ◽  
Book Of Hours ◽  
Almost All

The Thomas More Society of Buenos Aires begins or ends almost all its events by reciting in both English and Spanish a prayer written by More in the margins of his Book of Hours probably while he was a prisoner in the Tower of London. After a short history of what is called Thomas More’s Prayer Book, the author studies the prayer as a poem written in the form of a psalm according to the structure of Hebrew poetry, and looks at the poem’s content as a psalm of lament.

Auto Markets in the World and Strategy of Japan’s Companies

2019 ◽  
Vol 10 (10) ◽  
pp. 1003-1008
Author(s):  
Hiroyuki Matsuoka ◽  
Keyword(s):  
Saudi Arabia ◽  
Electric Vehicle ◽  
New Technologies ◽  
Auto Industry ◽  
Domestic Market ◽  
Automatic Driving ◽  
The World ◽  
Almost All ◽  
Made In

In the world auto market, top three companies are VW(Volkswagen), Runault-Nissan-Mistubishi, and Toyota. About some selected countries and areas, China, England, Italy, Australia, Germany, Turkey, Russia, Sweden, USA, Brazil, UAE, Japan, Vietnam and Thailand are more competitive. However, the situation is different. Seeing monopolistic market countries and areas, Saudi Arabia, Taiwan, Korea, Malaysia, France, India, and Pakistan, in particular, the influence of Japan to Taiwan, India, and Pakistan is very big. But in Korea and France, their own companies’ brands occupy the market. In Japan domestic market, the overall situation is competitive. Almost all vehicles made in Japan are Japanese brand. From now on, we have to note the development of electric vehicle (EV) and other new technologies such as automatic driving and connected car. That is because they will give a great impact on the auto industry and market of Japan. Now Japan’s auto industry is going to be consolidated into three groups, Honda, Toyota group, and Renault-Nissan-Mitsubishi group for seeking the scale merit of economy. Therefore, I will pay attention to the worldwide development of EV and other new technologies and the reorganization of auto companies groups.

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