Evaluating Mortality Rate and Associated Parameters in Patients with Acute Coronary Syndrome

Author(s):  
Alireza Gheini ◽  
Ali Pooria ◽  
Afsoun Pourya

Background: Acute coronary syndrome (ACS) is one of the leading causes of mortality worldwide and is characterized by unstable angina or acute myocardial infarction. The aim of this study is to evaluate the clinical characteristics of patients who died of ACS. Methods: In this cross-sectional study, 1000 patients presenting ACS were included. Data and records of these patients were evaluated for parameters such as; deceased status, age, gender, diagnosis, ECG, common complaints, associated risk factors, Killip class, pulse, blood pressure, geographic setup (urban or rural), complications and season in which the disease was presented. Statistical analysis was performed on the data obtained using SPSS-win software. Results: The mortality rate among ACS patients in our study was 7.1%. Of these patients, AMI was the most prevalent diagnosis and chest pain was the most common complaint. Furthermore, low blood pressure, advanced age, increased pulse rate and fall/winter season were associated with the increased risk of mortality. ST deviation was the most seen ECG finding and most of the mortalities were within the 24 hours of admission. Conclusion: Our study reports risk factors associated with mortality in ACS patients. Advanced and timely therapeutic measurements are likely to reduce the incidence of mortality in these patients.

2020 ◽  
Vol 7 (2) ◽  
pp. 92-100
Author(s):  
Ni Luh Sri Wahyuni ◽  
Tina Handayani Nasution ◽  
Edy Widjajanto

The prevalence of Acute Coronary Syndrome (ACS) is increasing in both developed and developing countries. Uncontrolled risk factors such as smoking, hypertension, and fewer activities are the main causes of ACS recurrence within 30 days after the acute presentation. This study aims to analyze risk factors related to the recurrence rate of ACS patients in Pakraman and non-Pakraman villages in Buleleng Regency, Bali Province. Observational analytics with Cross-Sectional Study are used in this study involving 130 patients within 1 month. Data is collected through two (2) stages using a questionnaire. The bivariate analysis shows that both smoking groups (p = 0.003 and p = 0.008) and hypertension groups (p = 0.02 and p = 0.01) are associated with ACS recurrence, while physical activity groups are not related (p = 0.455 and p = 0.565). Logistic regression results show that smoking (5.633) is highly associated with ACS recurrence in Pakraman villages, while hypertension (4.784) is highly associated with ACS recurrence in non-Pakraman villages. ACS handling is important in the acute period and in the long-term to prevent the risk of recurrence.


2020 ◽  
Vol 58 (224) ◽  
Author(s):  
Sahadeb Prasad Dhungana ◽  
Arun Kumar Mahato ◽  
Rinku Ghimire ◽  
Rupesh Kumar Shreewastav

Introduction: Dyslipidemia is one of the major risk factors for acute coronary syndrome. Dyslipidemiawith an increase in total cholesterol, low-density lipoprotein cholesterol, triglycerides and decrease inhigh-density lipoprotein cholesterol is one of the major risk factors for the acute coronary syndromeand alone account for more than 50% of population attributable risk. This study was conducted tofind out the prevalence of dyslipidemia. Methods: This descriptive cross-sectional study was conducted in 105 patients admitted at thetertiary care center with a diagnosis of acute coronary syndrome from July 2018 to March 2019 afterapproval from the institutional review committee (Ref no. 205/2018). Fasting serum lipid profilewas obtained within 24 hours of hospitalization with the convenient sampling method. Data wereanalyzed with the help of the Statistical Package for Social Sciences version 20. Point estimation at95% Confidence interval was calculated along with frequency and proportion for binary data. Results: Out of 105 people, dyslipidemia was present in 51 (48.6%). The mean age of the participantswas 59.19±12.69 years. The majority 81 (77.1%) were male. The mean total cholesterol, triglycerides,low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol were 183.43±35.9 mg/dl, 140.59±46.83 mg/dl, 109.9±26.38 mg/dl and 41.17±4.78 mg/dl respectively. High total cholesteroland triglyceride were found in 34 (32.4%) each, low high-density lipoprotein in 31 (29.5%) and highlow-density lipoprotein in 22 (21%).  Conclusions: Dyslipidemia is a significant risk factor in patients with acute coronary syndromeand commonly associated with other risk factors. Careful attention to its management may help toreduce further events.


2019 ◽  
Vol 16 (2) ◽  
pp. 63-67
Author(s):  
Navaraj Paudel ◽  
Abhishek Maskey ◽  
Dipesh Karki ◽  
Sushant Katwal ◽  
Namrata Thapa

Background and Aims: Microalbuminuria (MA) (urinary albumin excretion of 30-299 mg/d in a 24 hours collection or 30-299 μg/mg creatinine in a spot collection) is well accepted marker of micro and macrovascular damage in patients with diabetes mellitus and is considered as a surrogate marker for endothelial dysfunction in diabetic and non-diabetic patients. This study has been undertaken to investigate the prevalence of microalbuminuria among non-diabetic Acute Coronary Syndrome (ACS) patients. Methods: A hospital based cross-sectional study of 100 consecutive non-diabetic ACS patients was done. Traditional risk factors (like smoking, hypertension, dyslipidemia, obesity) of coronary artery disease were studied for the association with microalbuminuria in study subjects. Investigations were carried out in all the cases as per proforma and entered in the SPSS software for analysis. Results: The prevalence of microalbuminuria in non-diabetic ACS patients in the study was 73% which was statistically significant (p=0.04). A statistically significant higher prevalence of microalbuminuria was seen with different presentations of ACS; being highest (81.96%) in NSTEMI followed by STEMI (63.15%) and Unstable Angina (55%). It was found to be significant with the history of smoking (81.25%, p=0.013) and hypertension (82.25%, p=0.013). No significant association was found with age, body mass index (BMI) and dyslipidemia. A statistically significant higher prevalence of microalbuminuria was seen with increasing number of risk factors. Conclusion: There is increased prevalence of microalbuminuria in ACS patents. MA was associated with statistically higher number of cases with history of smoking and hypertension and presence of increasing number of risk factors.


2021 ◽  
pp. 105477382110401
Author(s):  
Audai A. Hayajneh ◽  
Mohammad Rababa ◽  
Sami Al-Rawashedeh

The prevalence of prehospital delay is high among older adults with acute coronary syndrome (ACS). The current study aimed to examine the associated factors of prehospital delay among patients with ACS during the COVID-19 pandemic. This cross-sectional study was conducted on a convenience sample of 300 older adults with ACS admitted to the emergency department in Jordan. Data were collected from June 1 to September 1, 2020. Bivariate and multivariate analyses were used to explore the predictors of prehospital delay. Being widowed, educational level, pain intensity, the gradual onset of ACS symptoms, symptoms lasting for more than 30 minutes, patients’ feeling anxious about their ACS symptoms, patients’ perceiving their symptoms to be particularly dangerous, history of myocardial infarction (MI), and mode of transportation were associated with the time taken before seeking emergency care. Significant predictors of time to seek help were chief complaint of chest pain or palpitations, abrupt onset of symptoms, the associated symptom of vertigo, and a higher number of chronic illnesses; they explained about 17.9% of the variance in the time to seek care. The average time to seek care among patients with ACS during the COVID-19 pandemic was found to be longer than the average time reported by studies conducted prior the pandemic. Improved understanding of the associations between prehospital delay is crucial for optimal ACS patient outcomes under the impacts of the COVID-19 pandemic.


Background: Exodontia is one of the most frequently carried out procedures by a dental surgeon, mostly on an outpatient department basis. The reasons for performing exodontia include non-restorable teeth, periodontal disease, dental trauma, impacted tooth, orthodontic treatment and toothache. Complications in dental extraction are a commonly encountered problem in dental clinics. This knowledge can help dental surgeons make extractions less invasive, traumatic and complicated, enabling quicker recovery of the socket. The aim of this study was to recognize types, frequency and risk factors for complications after exodontia. Methods: This cross-sectional study enrolled patients who had exodontia done from July- September 2019, visiting OPD of the Oral surgery department of Altamash Institute of Dental Medicine, Karachi. Risk factors included demographic data, general health, past medical and dental history. Spearman’s correlation test was used to establish any relationship of variables with complications. Results: The study patients (126) included 72 females (mean age 39.1±13.39) and 54 males (mean age 41.1±14.93). The overall complications rate was found to be 7.1%, mainly arising from maxillary and mandibular third molars. The most common complications encountered were Hemorrhage, Pain, and Trismus. Increasing age and specific teeth extracted were associated with an increased risk for complications. However, post-operative complications which were encountered most of them were minor and handled on an outpatient department basis. Conclusion: Frequency and risk factors for complications after exodontia were found low3 (37.5%). While age and teeth extracted cannot be directly altered, these factors maybe indirectly modified, resulting in a potential decrease of postoperative complications.


Author(s):  
Amir Hossein Goudarzian ◽  
Hamid Sharif Nia ◽  
Heydar Tavakoli ◽  
Mohammad Ali Soleimani ◽  
Ameneh Yaghoobzadeh ◽  
...  

Cardiac depression is one of the most common psychological reactions of patients with acute coronary syndrome (ACS). This study aimed to determine the prevalence of cardiac depression and its related factors among patients with ACS. This cross-sectional study was conducted during 2016 in patients with ACS who were admitted to hospitals affiliated to the Mazandaran University of Medical Sciences, Iran. In the present study, 407 patients completed the Cardiac Depression Scale (CDS) within two months (March - June). The data were analyzed by a chi-square test and a general linear model multivariate analysis. According to the results, the mean cardiac depression score in patients with ACS was 109.00 ± 16.49 (CI95: 107.39 to 110.60). Among the participants, 37 (9.1%), 72 (17.7%), and 298 (73.2%) patients had mild, moderate, and severe levels of depression, respectively. Although the two-way ANOVA was not significant, but there was a difference between cardiac depression score of a type of ACS. Given the high prevalence of cardiac depression among these patients, it is necessary to develop measures for routine screening in cardiac treatment units.


Author(s):  
Chidinma Ifeyinwa Mmaju ◽  
Peter Osezele Okonudo ◽  
Gladys Ahaneku ◽  
Ufoaroh Chinyelu Uchenna

Background: Hypertension is a major modifiable risk factor for cardiovascular diseases and research studies done in Nigeria observed prevalence rate of hypertension to range from 26.4% to 36.9%. Aim: This study aimed to evaluate the sociodemographic, clinical, behavioral and cardiovascular risk factors associated with hypertension in Awka, South East, Nigeria. Methods: Cross-sectional study was used.391 participants aged from 18 years above were recruited for this study. Structured questionnaires were constructed in line with World Health Organization Step approach was utilized for data collection. Hypertension was defined as systolic blood pressure ≥ 140 mmHg and Diastolic blood pressure ≥ 90 mmHg. Chi-square and independent sample T test were used to test comparison between two groups. Results: The mean age of the subjects was 45.87±17. 49.33.7% of retired subjects has the highest prevalence was statistically associated with hypertension in occupational status of the subjects, marital status was statically significant with hypertension and prevalence of hypertension among the subjects were 81.1%, 8.5%, 8.6% for married, single and divorcee respectively, (P<0.001) and also no association was observed between hypertension and subjects that occasionally use high salt often(x2=0.341, P>0.001). Conclusion: The study showed that age, family history of hypertension, consistent increase in blood pressure, occupational and marital status are associated risk factors of hypertension in Awka, South East, Nigeria. There is need to create awareness on the risk factors and encourage changes in sedentary life style.


Author(s):  
Anika Boitchia ◽  
Shabnam Naher ◽  
Sabbir Pervez ◽  
Moyazzem Hossainc

Abstract The purpose of this cross-sectional quantitative study was to identify the prevalence and associated risk factors of hypertension among rural women. Data collection was carried out between March to June 2019 among 380 women in Kumarkhali Upazila, Kushtia, Bangladesh. Participants were interviewed with a structured questionnaire including background characteristics, anthropometric measurements, prevalence, and risk factors of hypertension. IBM SPSS version 25 was used for analyzing the data. The prevalence of hypertension and prehypertension among the total participants was 21.3% and 17.1%, respectively. The mean systolic and diastolic blood pressure was 126.65 (±19.31) mmHg and 77.21 (±12.51) mmHg. Association was found between the prevalence of hypertension and participant’s age, marital status, educational level, body mass index, intake of raw salt, secondary smoking, stress, and diabetes (p<0.05). Among the diabetic women, prehypertension and hypertension prevailed as 26.3% and 55.3% respectively. The lowest risk of hypertension was found with limited raw salt (aOR: 1.42) and red meat (aOR: 0.05) consumption. Hypertension was more likely to affect overweight (aOR: 3.98) and women aged 55 to 64 years (aOR: 13.44). Thus, effective and integrated intervention agendas are required for women, which can improve the rate of diagnosis and prevent uncontrolled hypertension in Bangladesh. Keywords: Prevalence, hypertension, women, blood pressure, risk factor, Bangladesh


2021 ◽  
pp. 39-40
Author(s):  
Avtar Singh Dhanju ◽  
Deepshikha Singla ◽  
Pashaura Singh ◽  
Ajay Chhabra ◽  
Sukhraj Kaur

Aim: The present study was undertaken with the aim to evaluate serum Gamma Glutamyl Transferase (GGT) levels in patients of acute coronary syndrome. Methodology: This cross-sectional study was conducted on 50 cases with acute coronary syndrome (Group A) and 50 healthy control subjects (Group B) meeting inclusion and exclusion criteria. Results: There is signicant rise in serum GGT levels in patients presenting with ACS in Group A as compared to Group B. Conclusion: Higher levels of GGT in ACS patients with risk factors such as hypertension, dyslipidemia and smoking may serve as biomarker to predict the occurrence of ACS.


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