Conspectus of Phytoconstituents and Pharmacological activities of Barleria lupulina Lindl.: A Review

2020 ◽  
Vol 06 ◽  
Author(s):  
Sabyasachi Banerjee ◽  
Subhasis Banerjee ◽  
Gaurab Kumar Jha ◽  
Sankhadip Bose
Keyword(s):  
Traditional Medicine ◽  
Folk Medicine ◽  
Immunomodulatory Activity ◽  
Traditional Medicines ◽  
Novel Drugs ◽  
The Family ◽  
Pharmacological Studies ◽  
Abundance And Diversity ◽  
Clinical Conditions ◽  
Body Ache

Folk medicine system served the mankind as remedy of several clinical conditions since antiquity. Abundance and diversity of synthetic medicaments eclipse the implementation of traditional medicines for some times but the adverse reactions of synthetic medicaments have shifted people to traditional medicine system again to retrieve its position. Over a duration of time advancement in research and technology on traditional medicine systems attracted people to start believing in the safety aspects of natural products. This review illustrates the diverse pharmacological benefits of numerous phytoconstituents of a magical plant, Barleria lupulina Lindl., belonging to the family Acanthaceaec, native to East Africa (Mauritius), Eastern India, Bangladesh; apart from that it is also cultured in some places like Sri Lanka. It is commonly known as hophead Philippine violet, Lal-tarokh, etc. Traditionally the plant leaves are utilized to medicate in snakebites, dog bites, swelling, boils, sexual disorder, cough, fever, body ache, eczema, itches, bleeding wounds and rheumatism. The other pharmacological properties include antibacterial, anti-inflammatory, antidiabetic, antiulcer, antimitotic, diuretic, saluretic, kaliuretic, antiarthritic, antiviral, psychopharmacological, anticancer, analgesic, antioxidant and immunomodulatory activity. Till date, diversified phytoconstituents were isolated and structurally elucidated, in which saponins, glycosides, resins, steroids, phenolic compounds, alkaloids, tannins and flavonoids are the predominant one. With this ample information, the herb can be considered for isolating biomarkers to develop new lead which eventually leads to the making of novel drugs. In an attempt to illuminate the importance of B. lupulina, this review has been developed upon contemplating its traditional, morphological, ecological, phytochemical, and pharmacological studies though few information is available in the web.

An overview on therapeutic potential of Iris Persica

2020 ◽  
Vol 06 ◽  
Author(s):  
Faiq H. S. Hussain ◽  
Hawraz Ibrahim M. Amin ◽  
Dinesh kumar Patel ◽  
Omji Porwal
Keyword(s):  
Therapeutic Potential ◽  
Biological Activities ◽  
Folk Medicine ◽  
Underground Storage ◽  
Kurdistan Region ◽  
Traditional Medicines ◽  
The Family ◽  
Storage Organs ◽  
Radical Generation ◽  
Perennial Herbs

: The family Iridaceae contains 92 genera and more than 1800 species, mostly perennial herbs with underground storage organs called rhizomes (bulbs). Some genera are important in traditional medicines, especially Iris and Gladiolus. The genus Iris belongs to this family and comprises about hundreds species among them, 12 species are found in Iraq. It has been widely used various medicines worldwide especially Iris persica is used in folk medicine in the Kurdistan region of Iraq as an effective treatment against tumours, antibacterial, antifungal and treating inflammation. Earlier finding confirmed that Iris persica and its constituents play role in the scavenging of free radical generation and prevention of disease pathogenesis. Each part of the Iris persica herb has some medicinal property. This review gives a eagle eye view mainly on the biological activities of the Iris persica and some of their compounds isolated, pharmacological actions of the Iris persica extracts and products, and plausible medicinal and therapeutically applications.

Therapeutic and Pharmaceutical Potential of Cinnamon

2022 ◽  
pp. 698-710
Author(s):  
Neha Mishra ◽  
Rashmi Srivastava
Keyword(s):  
Wide Spectrum ◽  
Folk Medicine ◽  
Common Species ◽  
New Drugs ◽  
Bioactive Constituents ◽  
Rheumatic Arthritis ◽  
The Family ◽  
Pharmacological Studies ◽  
Therapeutic Properties ◽  
The Himalaya

Cinnamon has been used as a spice, condiment, and aromatic plant since centuries ago. Cinnamon is a small evergreen tree belonging to the genus Cinnamomum in the family Lauraceae. There are more than 250 species of cinnamon worldwide. In India, Cinnamomum verum and Cinnamomum cassia are the most common species grown in the Himalaya region. They have been used as folk medicine for the treatment of nausea, flatulent dyspepsia, coughs, diarrhea, malaria, gastric disorder, and to alleviate pain and inflammation in rheumatic arthritis. Therapeutic properties of cinnamon are due to the presence of bioactive constituents such as p-coumaric, cinnamaldehyde, cinnamic acid, and eugenol. Cinnamaldehyde and eugenol are the major active constituents responsible for its characteristic flavor, aroma, and therapeutic properties. Pharmacological studies found that it could be a promising candidate with potential for designing new drugs. This review is aimed to summarize the ethanomedicinal importance, phytochemistry, and wide spectrum of pharmacological and therapeutic applications of cinnamon.

scholarly journals Clinical Effects of Krachaidum (Kaempferia parviflora): A Systematic Review

2016 ◽  
Vol 22 (3) ◽  
pp. 413-428 ◽  
Author(s):  
Surasak Saokaew ◽  
Preyanate Wilairat ◽  
Paranya Raktanyakan ◽  
Piyameth Dilokthornsakul ◽  
Teerapon Dhippayom ◽  
...  
Keyword(s):  
Folk Medicine ◽  
Clinical Effects ◽  
Kaempferia Parviflora ◽  
Safety And Efficacy ◽  
Future Studies ◽  
Erotic Stimuli ◽  
Hand Grip ◽  
The Family ◽  
Pharmacological Studies ◽  
Harmful Effects

Kaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and summarize the clinical evidences of Krachaidum in all identified indications. Of 683 records identified, 7 studies were included. From current clinical trials, Krachaidum showed positive benefits but remained inconclusive since small studies were included. Even though results found that Krachaidum significantly increased hand grip strength and enhanced sexual erotic stimuli, these were based on only 2 studies and 1 study, respectively. With regard to harmful effects, we found no adverse events reported even when Krachaidum 1.35 g/day was used. Therefore, future studies of Krachaidum are needed with regards to both safety and efficacy outcomes.

scholarly journals Prospects of Traditionally important Apocynaceae plants of India in Cancer Remediation

2019 ◽  
Vol 9 (1) ◽  
pp. 293-302
Author(s):  
Nirmala Devi ◽  
Ajay Kumar Gupta ◽  
Sunil K. Prajapati
Keyword(s):  
Anticancer Activity ◽  
Antimalarial Activity ◽  
Mechanistic Study ◽  
Electronic Journals ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Lead Compounds ◽  
Medicinal Use ◽  
Novel Drugs ◽  
The Family

Objectives: Apocynaceae Family plants in India had wide array of traditional uses and practised since years ago. This review aims to report selected plants of this possessing anticancer activity. Selected literature compiled from the search of electronic journals, books and encyclopedias etc. using search engines viz. Google, PubMed, Sciencedirect, GoogleScholar and SciFinder for all periods. The Dogbane family is includes atleast 150 genera and 1700 species. Around 25 genera and 50 species of the family reviewed here possess anticancer activity. The reason for this potential is due to: a) phytoconstituents b) poisonous constituents c) antimalarial activity and d) abundance of literature in traditional medicinal use.  Folk medicinal uses and reported anticancer potential suggests that the Apocynaceae plants can be formulated or developed into lead compounds or novel drugs or multidrug complex for treatment of cancer. Detailed screening of each species has to be performed in 64 pannel cell lines, mechanistic study performed clearly and effectiveness of extracts, fractions or pure isolated compounds is to be compared. Keywords:  Apocynaceae; Traditional Medicines; cancer; anticancer plants.

Therapeutic and Pharmaceutical Potential of Cinnamon

2020 ◽  
pp. 124-136
Author(s):  
Neha Mishra ◽  
Rashmi Srivastava
Keyword(s):  
Wide Spectrum ◽  
Folk Medicine ◽  
Common Species ◽  
New Drugs ◽  
Bioactive Constituents ◽  
Rheumatic Arthritis ◽  
The Family ◽  
Pharmacological Studies ◽  
Therapeutic Properties ◽  
The Himalaya

Cinnamon has been used as a spice, condiment, and aromatic plant since centuries ago. Cinnamon is a small evergreen tree belonging to the genus Cinnamomum in the family Lauraceae. There are more than 250 species of cinnamon worldwide. In India, Cinnamomum verum and Cinnamomum cassia are the most common species grown in the Himalaya region. They have been used as folk medicine for the treatment of nausea, flatulent dyspepsia, coughs, diarrhea, malaria, gastric disorder, and to alleviate pain and inflammation in rheumatic arthritis. Therapeutic properties of cinnamon are due to the presence of bioactive constituents such as p-coumaric, cinnamaldehyde, cinnamic acid, and eugenol. Cinnamaldehyde and eugenol are the major active constituents responsible for its characteristic flavor, aroma, and therapeutic properties. Pharmacological studies found that it could be a promising candidate with potential for designing new drugs. This review is aimed to summarize the ethanomedicinal importance, phytochemistry, and wide spectrum of pharmacological and therapeutic applications of cinnamon.

Anatomy, histochemistry and phytochemical profile of leaf and stem bark of Bathysa cuspidata (Rubiaceae)

2012 ◽  
Vol 60 (1) ◽  
pp. 49 ◽  
Author(s):  
Victor Peçanha de Miranda Coelho ◽  
João Paulo Viana Leite ◽  
Líria Granato Nunes ◽  
Marília Contin Ventrella
Keyword(s):  
Environmental Sustainability ◽  
High Performance ◽  
Folk Medicine ◽  
Stem Bark ◽  
Plant Parts ◽  
The Family ◽  
Pharmacological Studies ◽  
Phytochemical Profile ◽  
Microscopy Techniques ◽  
Layer Chromatography

Bathysa cuspidata (A. St. Hil.) Hook. f. ex K. Schum. is a species native to the Atlantic Rainforest of Brazil, with stem bark currently used in folk medicine. Uncontrolled bark collections cause problems of environmental sustainability, making it necessary to evaluate more abundant and renewable new sources of raw plant material, such as leaves. This work evaluated the anatomy, histochemistry and phytochemistry of leaves and stem bark of B. cuspidata, aiming to find similarities in the chemical composition between these plant parts and to provide anatomical data to supplement the quality control of this plant drug. Common light and scanning electron microscopy techniques were used in the anatomical and histochemical studies. Thin-layer chromatography and high-performance liquid chromatography were used for the phytochemistry analysis. The concentration of total phenolics was determined using the Folin–Ciocalteau method and the contents of proanthocyanidins using the vanillin reagent. The leaves and bark of B. cuspidata display morphoanatomical characters common to the family Rubiaceae. The histochemical and phytochemical results reveal similarities and differences between the leaves and bark of B. cuspidata, suggesting that the extracts of both parts should be considered and subjected to pharmacological studies in order to investigate the effectiveness of the therapeutic actions reported in folk medicine.

scholarly journals Medical Pluralism among the Tharus of Nepal: Legitimacy, Hierarchy and State Policy

2019 ◽  
Vol 13 ◽  
pp. 58-66 ◽  
Author(s):  
Bamdev Subedi
Keyword(s):  
Health Care ◽  
Traditional Medicine ◽  
Health Care System ◽  
Oral Tradition ◽  
Folk Medicine ◽  
State Regulation ◽  
Medical Pluralism ◽  
Traditional Medicines ◽  
Official Recognition ◽  
Care System

This paper offers an understanding of medical pluralism as practiced among the Tharus of Nepal, and makes a discussion on the indigenous medicine in relation to the state health policy and the ambivalence that exists regarding official recognition of indigenous healers. Field data were collected from a village cluster of Dang district following qualitative methods: observation of healing sessions, interview with healers, patients, and key informants. Tharu healing tradition consists of three main practices: shamanic, herbal, and midwifery; practiced mainly by three types of healers: guruwa, baidawa, and surenya who employ three major strategies of healing: mantra, medicine and massage. The knowledge of healing mantras, use of local herbal medicine, and traditional midwifery and massage are the most important features of the Tharu’s indigenous healing practices. Such practices, along with those of co-inhabited non-Tharu healers and healing practices form the universe of local folk medicine. The folk medicine, which represents an oral tradition, co-exists along with scholarly traditional medicine and biomedicine. In terms of official recognition and support, biomedicine is on the top followed by scholarly traditional medicine and folk medicine falls at the bottom of the hierarchy. The scope of medical pluralism has been widened with the inclusion of scholarly traditional medicine in the official health care system. However, many of the indigenous traditional medicines that indigenous ethnic communities continue to practice still fall outside the purview of state regulation. The legitimacy of indigenous healers remains in question. An expression of sceptical and ambivalence attitudes towards indigenous healers has been reflected in the policy and planning documents. There has been an insignificant and inconsistent efforts to link indigenous healers with the official health care system and a hesitation to legitimize indigenous traditional medicine. A serious reflection is needed to move ahead from this ambivalence and inaction towards a more inclusive and democratic medical pluralism.

scholarly journals The GenusSpilanthesEthnopharmacology, Phytochemistry, and Pharmacological Properties: A Review

2013 ◽  
Vol 2013 ◽  
pp. 1-22 ◽  
Author(s):  
Jayaraj Paulraj ◽  
Raghavan Govindarajan ◽  
Pushpangadan Palpu
Keyword(s):  
Traditional Medicine ◽  
Biological Activities ◽  
Mechanisms Of Action ◽  
Biologically Active ◽  
The Internet ◽  
Pharmacological Properties ◽  
Pharmacological Effects ◽  
Over The Counter ◽  
Traditional Medicines ◽  
Pharmacological Studies

Spilanthesspp. are popular, over-the-counter remedies; they are sold over the internet under various names and are widely used in traditional medicine in various cultures. This review will summarize the important reports on the ethnopharmacology, botany, phytochemistry, and pharmacological properties as described in the literature from recent years (1920 to 2013).Spilanthesspp. are used for more than 60 types of disorders. They are reported to contain a number of biologically active phytochemicals, although a large number of ethnopharmacological uses have been documented; only a few of these species have been investigated for their chemical and biological activities. The studies are carried out mainly onSpilanthesextracts and a few metabolites substantiate the uses of these plants in traditional medicine. Well-conducted pharmacological studies are still needed for several traditional indications, and the mechanisms of action by which the plant extracts and the active compounds exert their pharmacological effects remain to be studied. They are predominantly used as extracts in personal care products, traditional medicines, and the pharmaceutical and culinary areas. Suggestions are made regarding some of the possible mechanisms of action as to how the known compounds may exert their biological activity.

scholarly journals Phytochemical and Pharmacological Studies on the GenusPsoralea: A Mini Review

2016 ◽  
Vol 2016 ◽  
pp. 1-17 ◽  
Author(s):  
Cong-Cong Li ◽  
Teng-Long Wang ◽  
Zhong-Qun Zhang ◽  
Wen-Qiang Yang ◽  
Yue-Fei Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Cardiovascular Diseases ◽  
Traditional Chinese Medicine ◽  
Skin Diseases ◽  
Folk Medicine ◽  
Psoralea Corylifolia ◽  
The Past ◽  
The Family ◽  
Pharmacological Studies ◽  
The World

The genusPsoralea, which belongs to the family Fabaceae, comprisesca.130 species distributed all over the world, and some of the plants are used as folk medicine to treat various diseases.Psoralea corylifoliais a typical example, whose seeds have been widely used in many traditional Chinese medicine formulas for the treatment of various diseases such as leucoderma and other skin diseases, cardiovascular diseases, nephritis, osteoporosis, and cancer. So, the chemical and pharmacological studies on this genus were performed in the past decades. Here, we give a mini review on this genus about its phytochemical and pharmacological studies from 1910 to 2015.

Level of use and public awareness in consumption of traditional medicines in work area of Health Center Gombong I

2020 ◽  
Vol 1 (3) ◽  
pp. 26-31
Author(s):  
Naelaz Zukhruf Wakhidatul Kiromah ◽  
Tri Cahyani Widiastuti
Keyword(s):  
Traditional Medicine ◽  
Urban Communities ◽  
Health Center ◽  
Public Awareness ◽  
Modern Medicine ◽  
Traditional Medicines ◽  
Rural And Urban ◽  
Work Area ◽  
Level Of Use ◽  
Minor Ailments

Indonesia has 20,000 types of plants where 300 species have been used as traditional medicines. The use of traditional medicine as an alternative treatment in Indonesia that has been used by both rural and urban communities. The use of traditional medicine is considered safer than modern medicine. The purpose of this study was to identify the level of use of traditional medicine and public awareness in the use of traditional medicine in work area of  Health Center Gombong 1 which consists of 5 villages. This research is a non-experimental and descriptive research that uses a questionnaire. Respondents who participated in this study were 140 people. The characteristics of respondents who participated in this study were the majority of men (50,71%), last educated of elementary school (41,43%), as housewives (27,86%). The majority of people in work area of Health Center Gombong choose treatment with modern medicine (64,29%). In addition there are 35,71% using traditional medicine and the majority use rhizome species (46%) for the treatment of minor ailments. In this study also showed that the majority of people do not know the safety of traditional medicines (50%) due to lack of information so that information is needed on the benefits and safety and the use of good and appropriate traditional medicines.

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