The Role of Pratisarana Kshara in the management of External Abscess

2018 ◽  
Vol 3 (5) ◽  
Author(s):  
Dr. Savadi B. S. ◽  
Hiremath Sangameshwar ◽  
Dr. Aakash Kembhavi
Keyword(s):  
Salivary Gland ◽  
Clinical Features ◽  
Treatment Modality ◽  
The Body ◽  
Local Temperature ◽  
Incision And Drainage

Abscess is an acquired condition seen all over the body. The clinical features of abscess are swelling, pain, redness, local temperature and tenderness. Salivary gland infection complications are uncommon. Submandibular abscess is caused when a salivary gland infection is left untreated, pus can collect and cause an abscess. Here, the commonly used treatment is incision and drainage followed by antibiotics which may have chance of re-occurrences. Hence, incision and drainage followed by the use of Pratisarana Kshara was used as the treatment modality to cure submandibular abscess.

scholarly journals How Temperature Pharmacology Was Formed: History in Personalities

2020 ◽  
Vol 10 (4-s) ◽  
pp. 226-231
Author(s):  
Aleksandr L. Urakov
Keyword(s):  
Mechanism Of Action ◽  
The Body ◽  
Local Temperature ◽  
In Vitro Experiments ◽  
Isolated Mitochondria ◽  
Keywords History Of Science ◽  
History Of ◽  
New Ideas

It is shown that temperature pharmacology is a new scientific and practical direction in which the local interaction of drugs is considered taking into account the local temperature of selected parts of the body. It is indicated that the main provisions of this direction were formulated in Russia by 1988. Catalysts for the formation of a new direction were the results of in vitro experiments with isolated mitochondria at different local temperatures. The chronology of the resolution of contradictions between the existing public opinion and new ideas about the role of local temperature in the mechanism of action of drugs in hypoxia and ischemia is indicated.  Scientists, doctors and journalists who were the first to believe in the prospects of temperature pharmacology are listed. The first scientific articles and inventions that formed the basis of a new scientific direction are presented. The latest achievements and visible prospects for the development of temperature pharmacology in medicine, biology, pharmacology and pharmacy are indicated. Keywords: history of science, pharmacology, pharmacy, medicines, local temperature.

scholarly journals Epithelial-Mesenchymal Interactions in Embryogenesis and Head and Neck Tumors

2019 ◽  
Vol 2 (1) ◽  
pp. 01-08
Author(s):  
Lekshmy Jayan ◽  
R. Bharanidharan ◽  
Ramya Ramdas
Keyword(s):  
Salivary Gland ◽  
Epithelial Mesenchymal Transition ◽  
Pathological Process ◽  
The Body ◽  
Important Process ◽  
Mesenchymal Transition ◽  
Neck Tumors ◽  
Pathological Conditions ◽  
Organ Systems

Epithelial mesenchymal interactions are one of the most important process taking place in the body. It is an indispensable mechanism that mediates the development of numerous organs and organ systems especially tooth, salivary gland etc. It has been long implicated in the causation of numerous pathogenic processes especially cancer. The mechanism of epithelial mesenchymal interactions are a forerunner for epithelial mesenchymal transition, which is an important pathological process in the development of cancer. In this review, we have highlighted the role of epithelial mesenchymal interactions in normal embryogenesis as well in numerous pathological conditions.

The Role of Extracellular Matrix in the Morphogenesis and Differentiation of Salivary Glands

1990 ◽  
Vol 4 (1) ◽  
pp. 27-33 ◽  
Author(s):  
L.S. Cutler
Keyword(s):  
Extracellular Matrix ◽  
Salivary Gland ◽  
Type Iv Collagen ◽  
The Body ◽  
Secretory Cells ◽  
Type Iv ◽  
Preliminary Information ◽  
Extracellular Matrix Molecules ◽  
Gland Morphogenesis

The processes of morphogenesis and cytodifferentiation are partially linked, independently regulated processes. The full expression of both processes is modulated or controlled, at least in part, by components of the extracellular matrix. This paper reviews the body of work that demonstrates a role for epithelial-mesenchymal interactions and various extracellular matrix molecules in the induction, control, and maintenance of salivary gland morphogenesis and cytodifferentiation. In addition, new, preliminary information which further elucidates the role of laminin and type IV collagen in the processes of morphogenesis and cytodifferentiation is presented. With regard to the role of extracellular matrix molecules in the regulation of salivary gland morphogenesis and cytodifferentiation, it appears that types I, III, and IV collagen, laminin, and chondroitin sulfate proteoglycan play roles in the control of glandular morphogenesis. With the exception of type IV collagen, these molecules do not appear to be involved in the regulation of cytodifferentiation of salivary gland secretory cells. On the other hand, of the extracellular matrix molecules tested so far, only type IV collagen appears to play a role in the regulation of salivary gland secretory cell differentiation.

MULTI-MODALITY IMAGING OF SALIVARY GLAND TUMORS

2021 ◽  
pp. 39-41
Author(s):  
Yashvant Singh ◽  
Namrita Sachdev ◽  
Akhila Prasad ◽  
Rushil Jain ◽  
Dinesh Sethi
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Cell Cancer ◽  
Myoepithelial Cells ◽  
The Body ◽  
Salivary Gland Tumors ◽  
Upper Aerodigestive Tract ◽  
Cross Sectional ◽  
Cross Sectional Imaging

Background: Imaging of salivary gland tumors is a challenge for the radiologist due to varied histological features and overlapping clinical presentation.The salivary glands have a glandular structure with tubules, secretory acini and myoepithelial cells to produce and secrete saliva. They are divided into two types: major and minor. Parotid, submandibular, and sublingual glands are the major paired salivary glands of the body. Multiple small minor salivary glands are distributed in the upper aerodigestive tract including PNS & parapharyngeal spaces. Objective: This study evaluates the role of different modalities used to assess salivary gland tumors. Results: 50 patients presenting with suspected salivary gland masses were evaluated. 22 males and 28 females were assessed with age ranging from 15 to 66 years (mean age of 52 years). 27 cases were of pleomorphic adenoma, 10 warthin tumors, 2 intraductal papilloma,1 lipoma, 1 oncocytoma,1 intra parotid paraganglioma, 2 hemangioma, 3 muco-epidermoid carcinoma, 2 adeno cystic cancer and 1 acinic cell cancer of salivary gland. 90% of patients (45 out of 50) presented with swelling / lump. 26% of patients had pain /discomfort and 4% of patients (2 out of 50) had facial nerve palsy. Conclusion: The conventional radiological evaluation was carried out using Xray and ultrasound with USG as rst line of investigation.. Cross sectional imaging with CT and MRI is useful in assessing for local extension , invasion of neighbouring structures as well as lymph nodal and systemic metastasis.MRI is superior to CT in assesing for extent and perineural spread.

scholarly journals Role of risk factors, clinical features and treatment modality in early detection and management of Buerger’s disease: a study from tertiary care centre Pondicherry

2020 ◽  
Vol 7 (6) ◽  
pp. 1718
Author(s):  
Krithika Kiruba ◽  
Himadra Koranga ◽  
Chandrasekaran Ramaraj ◽  
Anant A. Takalkar
Keyword(s):  
Risk Factors ◽  
Early Detection ◽  
Clinical Features ◽  
Lower Limb ◽  
Treatment Modality ◽  
Tertiary Care ◽  
Age Group ◽  
Buerger’S Disease ◽  
Buerger's Disease

Background: Thromboangiitis obliterans is a disease of unknown aetiology seen under 45 years of age with no form of treatment has been successful in offering the victims of this disease a cure nor even a long-term remission. Objective of the study was to study the role of different risk factors, clinical features and treatment modality in early detection and management of Buerger’s disease.Methods: This is an experimental study carried out in 50 cases of Buerger’s disease after obtaining a well-informed written consent in department of General Surgery in Aarupadai Veedu Medical College and Hospital. Period of study was from October 2015 to October 2017. Data was analysed with SPSS 23.0 version.Results: Majority were from 31-40 years age group i.e. 30 (60%). Left lower limb was involved in 52% subjects. 80% smoked more than 20 cigarettes per day. Signs of ischemia was present in all 50 patients. Gangrene of the limb was seen in 14 patients (28%). Out of 3 patients with recurrent pain, 2 (66.7%) were relieved. Ulcer healing occurred in 5 out of 6 patients i.e. 83.3% and intermittent claudication was relieved in 2 out of 7 patients i.e. 28.6%.Conclusions: Males are commonly involved in our study. Majority of patients were in age group 31-40 years. Smoking is an important and definite risk factor in relation with the development of Buerger’s disease. Lower limb is commonly involved. Majority of patients in our series were treated by conservative management.

scholarly journals Epithelial-Mesenchymal Interactions in Embryogenesis and Head and Neck Tumors

2019 ◽  
Vol 1 (2) ◽  
pp. 01-08
Author(s):  
Lekshmy Jayan
Keyword(s):  
Salivary Gland ◽  
Epithelial Mesenchymal Transition ◽  
Pathological Process ◽  
The Body ◽  
Important Process ◽  
Mesenchymal Transition ◽  
Neck Tumors ◽  
Pathological Conditions ◽  
Organ Systems

Epithelial mesenchymal interactions are one of the most important process taking place in the body. It is an indispensable mechanism that mediates the development of numerous organs and organ systems especially tooth, salivary gland etc. It has been long implicated in the causation of numerous pathogenic processes especially cancer. The mechanism of epithelial mesenchymal interactions are a forerunner for epithelial mesenchymal transition, which is an important pathological process in the development of cancer. In this review, we have highlighted the role of epithelial mesenchymal interactions in normal embryogenesis as well in numerous pathological conditions.

The Role of Polyphenols in the Modulation of Plasma Non-Enzymatic Antioxidant Capacity (NEAC)

2012 ◽  
Vol 82 (3) ◽  
pp. 228-232 ◽  
Author(s):  
Mauro Serafini ◽  
Giuseppa Morabito
Keyword(s):  
Antioxidant Capacity ◽  
Dietary Intervention ◽  
Ex Vivo ◽  
The Body ◽  
Dietary Polyphenols ◽  
Enzymatic Antioxidant ◽  
Endogenous Antioxidant

Dietary polyphenols have been shown to scavenge free radicals, modulating cellular redox transcription factors in different in vitro and ex vivo models. Dietary intervention studies have shown that consumption of plant foods modulates plasma Non-Enzymatic Antioxidant Capacity (NEAC), a biomarker of the endogenous antioxidant network, in human subjects. However, the identification of the molecules responsible for this effect are yet to be obtained and evidences of an antioxidant in vivo action of polyphenols are conflicting. There is a clear discrepancy between polyphenols (PP) concentration in body fluids and the extent of increase of plasma NEAC. The low degree of absorption and the extensive metabolism of PP within the body have raised questions about their contribution to the endogenous antioxidant network. This work will discuss the role of polyphenols from galenic preparation, food extracts, and selected dietary sources as modulators of plasma NEAC in humans.

The Role of Computer Modeling in Electrocardiography

1990 ◽  
Vol 29 (04) ◽  
pp. 282-288 ◽  
Author(s):  
A. van Oosterom
Keyword(s):  
Electrical Activity ◽  
Computer Modeling ◽  
Body Surface ◽  
Electrical Current ◽  
The Body ◽  
Volume Conductor ◽  
Current Generator ◽  
Cardiac Electrical Activity ◽  
Source Models

AbstractThis paper introduces some levels at which the computer has been incorporated in the research into the basis of electrocardiography. The emphasis lies on the modeling of the heart as an electrical current generator and of the properties of the body as a volume conductor, both playing a major role in the shaping of the electrocardiographic waveforms recorded at the body surface. It is claimed that the Forward-Problem of electrocardiography is no longer a problem. Several source models of cardiac electrical activity are considered, one of which can be directly interpreted in terms of the underlying electrophysiology (the depolarization sequence of the ventricles). The importance of using tailored rather than textbook geometry in inverse procedures is stressed.

Questions on the role of biofilms for the adaptation of microorganisms to unfavorable environmental factors by the example of P. aeruginosa

2020 ◽  
Vol 99 (4) ◽  
pp. 379-383
Author(s):  
Vasily N. Afonyushkin ◽  
N. A. Donchenko ◽  
Ju. N. Kozlova ◽  
N. A. Davidova ◽  
V. Yu. Koptev ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Environmental Factors ◽  
Barrier Function ◽  
Infectious Agent ◽  
Antagonistic Activity ◽  
The Body ◽  
Main Function ◽  
Pathogenic Potential ◽  
The Face

Pseudomonas aeruginosa is a widely represented species of bacteria possessing of a pathogenic potential. This infectious agent is causing wound infections, fibrotic cystitis, fibrosing pneumonia, bacterial sepsis, etc. The microorganism is highly resistant to antiseptics, disinfectants, immune system responses of the body. The responses of a quorum sense of this kind of bacteria ensure the inclusion of many pathogenicity factors. The analysis of the scientific literature made it possible to formulate four questions concerning the role of biofilms for the adaptation of P. aeruginosa to adverse environmental factors: Is another person appears to be predominantly of a source an etiological agent or the source of P. aeruginosa infection in the environment? Does the formation of biofilms influence on the antibiotic resistance? How the antagonistic activity of microorganisms is realized in biofilm form? What is the main function of biofilms in the functioning of bacteria? A hypothesis has been put forward the effect of biofilms on the increase of antibiotic resistance of bacteria and, in particular, P. aeruginosa to be secondary in charcter. It is more likely a biofilmboth to fulfill the function of storing nutrients and provide topical competition in the face of food scarcity. In connection with the incompatibility of the molecular radii of most antibiotics and pores in biofilm, biofilm is doubtful to be capable of performing a barrier function for protecting against antibiotics. However, with respect to antibodies and immunocompetent cells, the barrier function is beyond doubt. The biofilm is more likely to fulfill the function of storing nutrients and providing topical competition in conditions of scarcity of food resources.

Receptions of the Past: Commemoration, Racism, Desire

Somatechnics ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 288-303
Author(s):  
Michael Connors Jackman
Keyword(s):  
Critical Point ◽  
Social Relations ◽  
White Privilege ◽  
Body Politic ◽  
The Body ◽  
Race And Racism ◽  
Lesbian And Gay ◽  
The Past ◽  
History Of

This article investigates the ways in which the work of The Body Politic (TBP), the first major lesbian and gay newspaper in Canada, comes to be commemorated in queer publics and how it figures in the memories of those who were involved in producing the paper. In revisiting a critical point in the history of TBP from 1985 when controversy erupted over race and racism within the editorial collective, this discussion considers the role of memory in the reproduction of whiteness and in the rupture of standard narratives about the past. As the controversy continues to haunt contemporary queer activism in Canada, the productive work of memory must be considered an essential aspect of how, when and for what reasons the work of TBP comes to be commemorated. By revisiting the events of 1985 and by sifting through interviews with individuals who contributed to the work of TBP, this article complicates the narrative of TBP as a bluntly racist endeavour whilst questioning the white privilege and racially-charged demands that undergird its commemoration. The work of producing and preserving queer history is a vital means of challenging the intentional and strategic erasure of queer existence, but those who engage in such efforts must remain attentive to the unequal terrain of social relations within which remembering forms its objects.

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