scholarly journals THE RELATIONSHIP BETWEEN CEREBROSPINAL FLUID PRESSURE AND ATHEROGENIC INDEX OF PLASMA IN IDIOPATIC INTRACRANIAL HYPERTENSION PATIENTS

2022 ◽  
Vol 8 (1) ◽  
pp. 11-15
Author(s):  
Fatma Şimşek ◽  
Recep Yevgi ◽  
Yıldız Dağcı

Background: Idiopathic intracranial hypertension (IIH) is a disease thought to be associated with obesity and rapid weight gain. There is no objective parameter with practical use in its follow-up and treatment other than optical coherence tomography. Objective: The aim of our study is to investigate the relationship between atherogenic index of plasma (AIP) and cerebrospinal fluid (CSF) pressure. Methods: Serum vitamin B12, vitamin D, homocysteine, folic acid, triglyceride (TG), high density lipoprotein cholesterol (HDL-C) levels, CSF pressure, CSF microprotein levels were recorded from the file data of patients diagnosed with IIH. AIP was calculated by dividing the TG level logarithmically by HDL-C. Height (kg) and weight (kg) data of the patients were used to calculate the body mass index (BMI). Results: File data of 64 patients were examined. 8 patients with secondary intracranial hypertension were excluded from the study. 80.36% of the patients were overweight, 16.07% were obese, 3.57% were with normal weight. There was no significant correlation between vitamin B12, vitamin D, homocysteine, HDL-C and CSF microprotein levels and CSF pressure level in patients with a diagnosis of IIH. There was a negative correlation between folic acid level and CSF pressure level, and a positive correlation between BMI, TG, AIP and CSF pressure level. Conclusion: Using folic acid supplements and drugs that reduce TG levels can contribute positively to the course of the disease.

2019 ◽  
Vol 10 (1) ◽  
pp. 2
Author(s):  
Magdalena Nowaczewska ◽  
Henryk Kaźmierczak

Headaches attributed to low cerebrospinal fluid (CSF) pressure are described as orthostatic headaches caused by spontaneous or secondary low CSF pressure or CSF leakages. Regardless of the cause, CFS leaks may lead to intracranial hypotension (IH) and influence cerebral blood flow (CBF). When CSF volume decreases, a compensative increase in intracranial blood volume and cerebral vasodilatation occurs. Sinking of the brain and traction on pain-sensitive structures are thought to be the causes of orthostatic headaches. Although there are many studies concerning CBF during intracranial hypertension, little is known about CBF characteristics during low intracranial pressure. The aim of this review is to examine the relationship between CBF, CSF, and intracranial pressure in headaches assigned to low CSF pressure.


Author(s):  
Habibesadat Shakeri ◽  
Amir Azimian ◽  
Hamed Ghasemzadeh‐Moghaddam ◽  
Mohammadreza Safdari ◽  
Mehdi Haresabadi ◽  
...  

PEDIATRICS ◽  
1972 ◽  
Vol 50 (4) ◽  
pp. 584-589
Author(s):  
Ambadas Pathak ◽  
Herman A. Godwin ◽  
Luis M. Prudent

The relationship of serum vitamin B12 and folic acid was studied in 24 premature infants. In 14 of the 24, low serum vitamin B12 values were found around 40 days of age. Serum folic acid concentrations were less frequently depressed and were usually associated with normal red cell folate values. No correlation between hematocrits and vitamin B12 or folate levels was found. It is suggested that low concentrations of serum folate and vitamin B12 result from low dietary intake coupled with increased demand by the prematurely born infant.


Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 337 ◽  
Author(s):  
Rondanelli ◽  
Faliva ◽  
Gasparri ◽  
Peroni ◽  
Naso ◽  
...  

Background and objective: Often micronutrient deficiencies cannot be detected when patient is already following a long-term gluten-free diet with good compliance (LTGFDWGC). The aim of this narrative review is to evaluate the most recent literature that considers blood micronutrient deficiencies in LTGFDWGC subjects, in order to prepare dietary supplementation advice (DSA). Materials and methods: A research strategy was planned on PubMed by defining the following keywords: celiac disease, vitamin B12, iron, folic acid, and vitamin D. Results: This review included 73 studies. The few studies on micronutrient circulating levels in long-term gluten-free diet (LTGFD) patients over 2 years with good compliance demonstrated that deficiency was detected in up to: 30% of subjects for vitamin B12 (DSA: 1000 mcg/day until level is normal, then 500 mcg), 40% for iron (325 mg/day), 20% for folic acid (1 mg/day for 3 months, followed by 400–800 mcg/day), 25% for vitamin D (1000 UI/day or more-based serum level or 50,000 UI/week if level is <20 ng/mL), 40% for zinc (25–40 mg/day), 3.6% of children for calcium (1000–1500 mg/day), 20% for magnesium (200–300 mg/day); no data is available in adults for magnesium. Conclusions: If integration with diet is not enough, starting with supplements may be the correct way, after evaluating the initial blood level to determine the right dosage of supplementation.


2020 ◽  
pp. 10.1212/CPJ.0000000000001022
Author(s):  
Mattia Sansone ◽  
Michelangelo De Angelis ◽  
Leonilda Bilo ◽  
Vincenzo Bonavita ◽  
Roberto De Simone

The intracranial pressure (ICP) show large daily fluctuation, mainly due to postural changes and physical activity (e.g. it goes up to 470 mmH2O under Valsalva manoeuvre1). Consequently, the dural sinus must be sufficiently rigid in order to avoid its collapse during cerebrospinal fluid (CSF) pressure peaks. Hereby, we describe a patient with collapsible dural sinus associated with an intracranial hypertension syndrome without a detectable raised ICP, suggesting that a number of crucial assumptions on idiopathic intracranial hypertension with (IIH) or without papilledema (IIHWOP) might be discussed.


Cornea ◽  
2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Mehmet Gökhan Aslan ◽  
Hüseyin Fındık ◽  
Murat Okutucu ◽  
Emre Aydın ◽  
Yavuz Oruç ◽  
...  

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