scholarly journals Effect of Ciprofloxacin on Recovery and Conception Rate in infectious Repeat Breeder Crossbred Cows

2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Sudarshan K. ◽  
Anavil Bhardwaz ◽  
S. P. Nema ◽  
Daljeet Chabbra ◽  
Supriya Shukla ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Animal Husbandry ◽  
Bacterial Count ◽  
Treated Group ◽  
Conception Rate ◽  
Control Group ◽  
Veterinary Science ◽  
Crossbred Cows ◽  
White Side ◽  
Repeat Breeder

The present study was undertaken to evaluate the therapeutic efficacy of Ciprofloxacinin in 20 infectious repeat breeder crossbred cows brought to the AI centre of Department of Veterinary Gynaecology and Obstetrics, College of Veterinary Science and Animal Husbandry, Mhow and nearby Government AI centers. Animals were divided into two groups ten in each .The animals in first group were treated with Ciprofloxacin Hydrochloride @ 4 mg/kg BW IU. The animals in control group were infused with 30 ml saline IU. Bacterial count, total Cellular count and PMNs values were reduced highly significantly (P Lass Than 0.01) in Ciprofloxacin treated group than in control group. 90.00 % cows under Ciprofloxacin treatment became negative to White side test. An overall conception rate of 70.00 per cent was found in Ciprofloxacin treated repeat breeder cross bred cows.

scholarly journals Immunomodulatory effect of Neem (Azadiracta indica) Extract on Recovery and Conception Rate in Infectious Repeat Breeder Crossbred Cows

2018 ◽  
Vol 14 (3) ◽  
Author(s):  
Sudarshan Kumar ◽  
Anavil Bhardwaz ◽  
S.P. Nema ◽  
S.S. Mahour ◽  
Daljeet Chabbra ◽  
...  
Keyword(s):  
Recovery Rate ◽  
Therapeutic Efficacy ◽  
Bacterial Count ◽  
Conception Rate ◽  
Control Group ◽  
Neem Extract ◽  
Crossbred Cows ◽  
Group A ◽  
Uterine Flushing ◽  
Repeat Breeder

The study was undertaken to evaluate the therapeutic efficacy of Neem (Azadiracta indica) extract in 20 infectious repeat breeder crossbred cows. Animals were divided into two groups of ten in each. The animals in first group were treated with 15% concentration of Neem extract w/v dissolved in saline to make 30 ml, Intra Uterine at 24 hrs intervals for 7 days, while the animals in control group were infused with 30 ml saline for 7 days. Bacterial count in uterine flushing declined significantly (p less than 0.05) after treatment in Neem group. A significant increase (p less than 0.05) in total cellular count and PMNs % was found in Neem group than in control group. An overall recovery rate of 80% vs 20% and conception rate of 50% vs 10% was found in Neem treated cows over control group proving its efficacy in infectious repeat breeder cows.

Effect of Garlic (Allium sativum) Extract on Recovery and Conception Rate in Infectious Repeat Breeder Crossbred Cows

2018 ◽  
Vol 14 (2) ◽  
Author(s):  
Anavil Bhardwaz ◽  
S. P. Nema ◽  
S. S. Mahour ◽  
Daljeet Chabbra ◽  
N. Rajput ◽  
...  
Keyword(s):  
Placebo Group ◽  
Recovery Rate ◽  
Allium Sativum ◽  
Bacterial Count ◽  
Conception Rate ◽  
Control Group ◽  
Crossbred Cows ◽  
Group A ◽  
Uterine Flushing ◽  
Repeat Breeder

The study was undertaken to evaluate the therapeutic efficacy of Garlic (Allium sativum) extract in 20 infectious repeat breeder crossbred cows. Animals were divided into two groups of ten in each. The animals in first group were treated intrauterine with 30 ml 15% Garlic extract w/v dissolved in saline at 24 hrs interval for 7 days, while the animals in control group were infused with 30 ml saline for 7 days. Bacterial count in uterine flushing declined significantly (p less than 0.05) after treatment in Garlic group. A significant increase (p less than 0.05) in total cellular count and PMNs % was found in Garlic group than in control group. An overall recovery rate of 80 vs 20 % and conception rate of 60 vs 10 % was found in Garlic treated cows over control placebo group proving its efficacy in infectious repeat breeders.

Therapeutic Efficacy of Garlic (Allium sativum), Turmeric (Curcuma longa) and Eucalyptus (Eucalyptus globules) Extracts in the Treatment of Bovine Endometritis

2021 ◽  
Author(s):  
D. Gopikrishnan ◽  
M. Selvaraju ◽  
M. Palanisamy ◽  
M. Periyannan ◽  
K. Ravikumar ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Curcuma Longa ◽  
Bacterial Load ◽  
Ethanolic Extract ◽  
Bacterial Count ◽  
Conception Rate ◽  
Treatment Result ◽  
Control Group ◽  
Group I ◽  
Group Ii

Background: Endometritis is one of the major causes of subfertility in bovines. The present study was conducted to evaluate the therapeutic efficacy of ethanolic extracts of garlic, turmeric and eucalyptus in the treatment of bovine endometritic as an alternative to antibiotics. Methods: Forty crossbred cows affected with endometritis were equally divided into 4 groups. Group I (control) cows were treated intrauterinely (i.u) with streptopenicillin 2.5 g + 30 ml normal saline for 3 days and group II, III and IV cows were treated (i.u) with 30-40 ml of ethanolic extract of garlic, turmeric and eucalyptus for 3 consecutive days. The animals were inseminated artificially on subsequent estrus after the treatment. Result: Bacterial count in uterine flushing declined significantly after treatment in all the four groups. The percentage of reduction in bacterial count was higher in garlic treated cows than in control and other treatment groups. A significant increase in percentage of PMNs was found after treatment in all the groups. The overall conception rate was 40% in control group, 50% in group II and 30% in group III and IV. It was concluded that ethanolic extract of garlic for the treatment of endometritis resulted in better conception rate and significantly higher percentage reduction of bacterial load than other treatment and control groups.

scholarly journals In vivo evaluation of a recombinant N-acylhomoserine lactonase formulated in a hydrogel using a murine model infected with MDR Pseudomonas aeruginosa clinical isolate, CCASUP2

AMB Express ◽  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Masarra M. Sakr ◽  
Walid F. Elkhatib ◽  
Khaled M. Aboshanab ◽  
Eman M. Mantawy ◽  
Mahmoud A. Yassien ◽  
...  
Keyword(s):  
Survival Rate ◽  
Murine Model ◽  
Histopathological Examination ◽  
Healing Process ◽  
Bacterial Count ◽  
Treated Group ◽  
Control Group ◽  
In Vivo Evaluation ◽  
Systemic Spread

AbstractFailure in the treatment of P. aeruginosa, due to its broad spectrum of resistance, has been associated with increased patient mortality. One alternative approach for infection control is quorum quenching which was found to decrease virulence of such pathogen. In this study, the efficiency of a recombinant Ahl-1 lactonase formulated as a hydrogel was investigated to control the infection of multidrug resistant (MDR) P. aeruginosa infected burn using a murine model. The recombinant N-acylhomoserine lactonase (Ahl-1) was formulated as a hydrogel. To test its ability to control the infection of MDR P. aeruginosa, a thermal injury model was used. Survival rate, and systemic spread of the infection were evaluated. Histopathological examination of the animal dorsal skin was also done for monitoring the healing and cellular changes at the site of infection. Survival rate in the treated group was 100% relative to 40% in the control group. A decrease of up to 3 logs of bacterial count in the blood samples of the treated animals relative to the control group and a decrease of up to 4 logs and 2.3 logs of bacteria in lung and liver samples, respectively were observed. Histopathological examination revealed more enhanced healing process in the treated group. Accordingly, by promoting healing of infected MDR P. aeruginosa burn and by reducing systemic spread of the infection as well as decreasing mortality rate, Ahl-1 hydrogel application is a promising strategy that can be used to combat and control P. aeruginosa burn infections.

scholarly journals Therapeutic Efficacy of Lugol’s Iodine (I2KI) in Infectious Repeat Breeder Crossbred Cows

2018 ◽  
Vol 7 (12) ◽  
pp. 648-654
Author(s):  
Anavil Bhardwaz ◽  
S.P. Nema ◽  
S.S. Mahour ◽  
Sreshti Bagati ◽  
Sudershan Kumar
Keyword(s):  
Therapeutic Efficacy ◽  
Crossbred Cows ◽  
Lugol’S Iodine ◽  
Repeat Breeder

Herbal Combo Therapy’ for Oestrus Induction in Postpartum Anoestrus Cows

2021 ◽  
Vol 10 (1) ◽  
pp. 19-21
Author(s):  
S Satheshkumar ◽  
◽  
N Punniamurthy ◽  
V Ranganathan ◽  
◽  
...  
Keyword(s):  
Moringa Oleifera ◽  
Aloe Vera ◽  
Follicular Development ◽  
Experimental Period ◽  
Conception Rate ◽  
Control Group ◽  
Treatment Schedule ◽  
Murraya Koenigii ◽  
Crossbred Cows ◽  
Sequential Administration

The research was aimed at studying the effect of a ‘Herbal combo therapy’ (HCT) on induction of oestrus and enhancement of fertility in postpartum anoestrus (PPA) in crossbred cows. Crossbred cows (n = 24) which were diagnosed for true anoestrus condition were utilized for the study. All the cows were dewormed and randomly divided into two groups (i) Control group (n = 10): No treatment schedule and (ii) Treatment group (n = 14): HCT involving a sequential administration of Raphanus sativus, Aloe vera, Moringa oleifera, Cissuss quadrangularisis and Murraya koenigii for a period of 20 days. The animals which expressed oestrus signs during the experimental period were inseminated and pregnancy was confirmed. Diameter of the largest follicle was documented on the initiation day of experiment and at the end of the experimental period or on the day of expression of induced oestrus. Perusal of the data revealed that 71.4 per cent of the PPA animals responded to the HCT by expressing oestrus signs within the experimental period as against 10.0 per cent in control group. The follicular diameter significantly increased in HCT group (11.8 + 2.4 mm) than the control group (9.6 + 0.8 mm). The overall conception rate among the PPA cows treated with HCT was much higher (57.1%) than the control group (10.0%). Steroidogenic activity, rich nutrient source and anti-inflammatory properties of HCT would have potentiated the follicular development and thereby induced oestrus and improved conception rate in anoestrus cows.

scholarly journals In Vivo Evaluation of a Recombinant N-acylhomoserine Lactonase Formulated in a Hydrogel Using a Murine Model Infected With Mdr Pseudomonas Aeruginosa Clinical Isolate, CCASUP2

2021 ◽  
Author(s):  
Masarra M. Sakr ◽  
Walid F. Elkhatib ◽  
Khaled Aboshanab ◽  
Eman M. Mantawy ◽  
Mahmoud A. Yassien ◽  
...  
Keyword(s):  
Survival Rate ◽  
Murine Model ◽  
Histopathological Examination ◽  
Healing Process ◽  
Bacterial Count ◽  
Treated Group ◽  
Control Group ◽  
In Vivo Evaluation ◽  
Systemic Spread

Abstract Failure in the treatment of P. aeruginosa, due to its broad spectrum of resistance, has been associated with increased patient mortality. One alternative approach for infection control is quorum quenching which was found to decrease virulence of such pathogen. In this study, the efficiency of a recombinant Ahl-1 lactonase formulated as a hydrogel was investigated to control the infection of multidrug resistant (MDR) P. aeruginosa infected burn using a murine model. The recombinant N-acylhomoserine lactonase (Ahl-1) was formulated as a hydrogel. To test its ability to control the infection of MDR P. aeruginosa, a thermal injury model was used. Survival rate, and systemic spread of the infection were evaluated. Histopathological examination of the animal dorsal skin was also done for monitoring the healing and cellular changes at the site of infection. Survival rate in the treated group was 100% relative to 40% in the control group. A decrease of up to 3 logs of bacterial count in the blood samples of the treated animals relative to the control group and a decrease of up to 4 logs and 2.3 logs of bacteria in lung and liver samples, respectively were observed. Histopathological examination revealed more enhanced healing process in the treated group. Accordingly, by promoting healing of infected MDR P. aeruginosa burn and by reducing systemic spread of the infection as well as decreasing mortality rate, Ahl-1 hydrogel application is a promising strategy that can be used to combat and control P. aeruginosa burn infections.

Tryptophan-Niacin Metabolism in Rat with Puromycin Aminonucleoside-Induced Nephrosis

2006 ◽  
Vol 76 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Yukari Egashira ◽  
Shin Nagaki ◽  
Hiroo Sanada
Keyword(s):  
Body Weight ◽  
Urinary Excretion ◽  
Enzyme Activities ◽  
Treated Group ◽  
Control Group ◽  
Puromycin Aminonucleoside ◽  
Low Level ◽  
Key Enzyme

We investigated the change of tryptophan-niacin metabolism in rats with puromycin aminonucleoside PAN-induced nephrosis, the mechanisms responsible for their change of urinary excretion of nicotinamide and its metabolites, and the role of the kidney in tryptophan-niacin conversion. PAN-treated rats were intraperitoneally injected once with a 1.0% (w/v) solution of PAN at a dose of 100 mg/kg body weight. The collection of 24-hour urine was conducted 8 days after PAN injection. Daily urinary excretion of nicotinamide and its metabolites, liver and blood NAD, and key enzyme activities of tryptophan-niacin metabolism were determined. In PAN-treated rats, the sum of urinary excretion of nicotinamide and its metabolites was significantly lower compared with controls. The kidneyα-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) activity in the PAN-treated group was significantly decreased by 50%, compared with the control group. Although kidney ACMSD activity was reduced, the conversion of tryptophan to niacin tended to be lower in the PAN-treated rats. A decrease in urinary excretion of niacin and the conversion of tryptophan to niacin in nephrotic rats may contribute to a low level of blood tryptophan. The role of kidney ACMSD activity may be minimal concerning tryptophan-niacin conversion under this experimental condition.

Haemostatic Clot Formation at Anastomosis of Synthetic Venous Graft in Defibrinogenated Dogs: A Scanning Electron Microscopic Study

1981 ◽  
Vol 45 (03) ◽  
pp. 276-281 ◽  
Author(s):  
S Ishimaru ◽  
E Berglin ◽  
H-A Hansson ◽  
A-C Teger-Nilsson ◽  
G William-Olsson
Keyword(s):  
Vena Cava ◽  
Treated Group ◽  
Control Group ◽  
Electron Microscopic ◽  
Scanning Electron Microscopic Study ◽  
Fibrin Network ◽  
Scanning Electron Microscopic ◽  
Expanded Polytetrafluoroethylene Graft ◽  
Morphological Differences ◽  
Scanning Electron

SummaryA segment of the inferior vena cava was replaced by an expanded polytetrafluoroethylene graft in 13 dogs. Five of them served as a control group, while the other 8 were moderately or severely defibrinogenated with subcutaneous batroxobin. Plasma fibrinogen decreased to extremely low values throughout the experiment in the defibrinogenated dogs except in the moderately treated group in which it temporarily rose to 0.72-0.87 g/1 on the first postoperative day.Scanning electron microscopic observations of the haemostatic clot formed at the anastomoses of the graft revealed no significant morphological differences in platelet adhesion and/or aggregation between the three groups. These findings confirmed that platelets play a key role in primary haemostasis during defibrinogenation.The fibrin network was slightly diminished and only short fibrin filaments could be seen in the moderately and severely defibrinogenated groups respectively. These differences in composition of the clots are discussed in relation to their haemostatic capacity.

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