Exponential growth impact of COVID-19 pandemic-world scenario, preventive measures and drug preferences (Preprint)

2020 ◽  
Author(s):  
Aneesh Kumar K V

BACKGROUND The World Health Organization (WHO) declared 2019-20 coronavirus outbreak as a Public Health Emergency of International Concern (PHEIC) on 30 January 2020 and pandemic on 11 March 2020. As of today, 17 May 2020 around 3,16,520 death and 47,99,266 coronavirus infected cases are reported worldwide. There is about 26,25,463 active cases are now under treatment and several lakhs of people are under quarantine. Therefore, an attempt has been made to explain briefly about the characteristics of the virus, current review, COVID-19 symptoms, precautions, available vaccines etc. In addition, a case study was also conducted to provide the dangerous picture of drastic growth of infected people around the world during the span of time. OBJECTIVE World Health Organization (WHO) has announced the COVID-19 outbreak as a global public health emergency and pandemic, spreading fast with an increasing number of infected patients worldwide. At present, no vaccines are available for the treatment of patients with COVID_19 disease. A case study was conducted to provide the dangerous picture of exponential growth of infected people around the world to inculcate the awareness of maintaining social distancing and hand hygiene. This effort is made in view of providing awareness to the public effectively to understand and deal with the novel coronavirus situation worldwide. It is also anticipated to provide a reference to future advances in medical anti-virus related studies. METHODS A case study was conducted to provide the dangerous picture of exponential growth of infected people around the globe. For our study, we preferred five most coronavirus effected countries in the world viz., China, Itali, USA, Spain, India in the month of February and March 2020, and later extended to 17 May 2020. Based on the current published evidence, we precisely summarize the disease, characteristics of the virus, current world scenario, available treatment options and preventive measures to be taken against COVID-19. RESULTS Effort is made in view of providing awareness to the public effectively to understand and deal with the novel coronavirus situation worldwide.The medicines like Remdesivir, Chloroquine and Hydroxychloroquine, Ritonavir/Lopinavir and combined with Interferon beta are the experimental treatments currently being researched. Treatment with Lopinavir and Ritonavir or Chloroquine should be recommended in older patients with serious symptoms. The main risk factor of COVID-19 is travel and exposure to the virus. Lockdown, quarantine and thereby maintaining the ‘social distancing’ are the suitable method for controlling the out spread of coronavirus. Moreover, it is individual’s responsibility to take prompt measures to control the fast spreading of this virus disease. CONCLUSIONS The COVID-19 disease is spreading fast uncontrolled with an increasing number of infected patients worldwide. Our case study details the dangerous picture of exponential growth of infected people around the globe. The exact source, characteristics of the virus is unknown and no suitable drugs have been developed as of today. Symptomatic treatments are available and the list is provided, no need to panic. Conclusion is to inculcate the awareness of maintaining social distancing and hand hygiene. Anticipated to provide a reference to future advances in medical antivirus related studies.

Author(s):  
Kunal Agrawal ◽  
Prakash Kute ◽  
Ashish Anjankar ◽  
Roshan Kumar Jha

SARS-CoV-2, also known as COVID-19, is a novel coronavirus that has spread from Wuhan, China to every continent except Antarctica. On March 11, 2020, the World Health Organization (WHO) changed the situation's classification from a public health emergency of international concern to a pandemic. To date (17 April 2021), the novel coronavirus — officially known as "severe acute respiratory syndrome coronavirus 2," or SARS-CoV-2 for short — has caused over 140 Million infections and approximately 3 Million deaths around the world. In INDIA, the virus has infected nearly 14.3 Million people, with nearly 1,74,000 of them dying. (April 17, 2021) We have conducted a literature search around pub Med, Medline, Scopus, WHO, and web of science to distinguish the effect of myth vs. truth about COVID 19. Present study concludes Citizens' consciousness and the avoidance of misconceptions play a critical role in managing the pandemic, and as a result of this awareness, India's fatality rate is at 3.3 percent, with a recovery rate of 12.02 percent, according to the Health Ministry of India. The extraordinary effort to attain widespread vaccination coverage has been greeted with an assault of incorrect and misleading information. Misinformation has the potential to harm vaccination uptake. Debunking misleading claims is a prominent way of combating vaccination misinformation. As a result, dealing with COVID-19 vaccination disinformation involves proactive measures to “immunise the public against misinformation.”


2020 ◽  
Vol 3 (3) ◽  
pp. 01-02
Author(s):  
Khadiga Ismail

COVID-19 has high transmissibility and infectivity among human. On January 30, 2020, the World Health Organization (WHO) in an effort to slow down the global spread of the virus declared the outbreak, “A global public health emergency of international concern". The skin manifestations of the novel coronavirus COVID-19 were not recognized at the early stages of the pandemic but have received much recent attention in scientific journals. Reported manifestations range from pseudo-chilblains to a morbilliform (measles-like) exanthem, urticaria, vesicular eruptions, a dengue-like petechial rash and ovate scaling macules, and plaques mimicking pityriasis rosea.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Ghassane Benrhmach ◽  
Khalil Namir ◽  
Jamal Bouyaghroumni

The World Health Organization declared that the total number of confirmed cases tested positive for SARS‐CoV‐2, affecting 210 countries, exceeded 3 million on 29 April 2020, with more than 207,973 deaths. In order to end the global COVID‐19 pandemic, public authorities have put in place multiple strategies like testing, contact tracing, and social distancing. Predictive mathematical models for epidemics are fundamental to understand the development of the epidemic and to plan effective control strategies. Some hosts may carry SARS‐CoV‐2 and transmit it to others, yet display no symptoms themselves. We propose applying a model (SELIAHRD) taking in consideration the number of asymptomatic infected people. The SELIAHRD model consists of eight stages: Susceptible, Exposed, Latent, Symptomatic Infected, Asymptomatic Infected, Hospitalized, Recovered, and Dead. The asymptomatic carriers contribute to the spread of disease, but go largely undetected and can therefore undermine efforts to control transmission. The simulation of possible scenarios of the implementation of social distancing shows that if we rigorously follow the social distancing rule then the healthcare system will not be overloaded.


2020 ◽  
Vol 8 ◽  
Author(s):  
Xuanzhen Cen ◽  
Dong Sun ◽  
Ming Rong ◽  
Gusztáv Fekete ◽  
Julien S. Baker ◽  
...  

Recently, an unprecedented coronavirus pandemic has emerged and has spread around the world. The novel coronavirus termed COVID-19 by the World Health Organization has posed a huge threat to human safety and social development. This mini review aimed to summarize the online education mode and plans for schools to resume full-time campus study in China during COVID-19. Chinese schools have made significant contributions to the prevention and control of the transmission of COVID-19 by adopting online learning from home. However, normal opening and classroom teaching have been affected. For education systems at all levels, online education may be an effective way to make up for the lack of classroom teaching during the epidemic. To protect staff and students from COVID-19, the timing of students returning to full-time campus study needs to be considered carefully. Reviewing and summarizing of the Chinese education system's response to the virus would be of great value not only in developing educational policy but also in guiding other countries to formulate educational countermeasures.


Author(s):  
Ugbomah Lucy Ohoreorovwori ◽  
Stanley Catherine Nonyelum ◽  
Stanley Princewill Chukwuemeka

Background: Coronavirus disease (COVID-19) is a highly infectious disease caused by a novel coronavirus strain. The virus is believed to spread mainly by respiratory droplets where the infected people breathe, cough or sneeze and expel little droplets of moisture that contain the virus.Older people and people with pre-existing medical conditions are mostly affected. Method: Relevant literatures were reviewed from the internet, electronic and print media, World Health Organization and Center for Disease Control documentation. Results: The coronavirus has brought difficult situations for citizens across the world. Refugees and irregular migrants who find themselves in difficult situations are more vulnerable to the effect of the virus and the social difficulties associated with it. Conclusion: The spread of the virus can be slowed or suppressed through social distancing, natural immunity, and observance of optimal hygiene practice and near compulsory use of face masks, particularly while dealing with the public.


Author(s):  
Renée Belliveau

After the World Health Organization declared the spread of the novel coronavirus (COVID-19) a global pandemic in March 2020, they cautioned of another outbreak: an “infodemic.” This study examines how online search engines are influencing the global spread of immunization information about COVID-19. It aims to address the various ways in which search technology is shaping users’ perceptions of the pandemic and to measure the credibility of the sources they provide.


2020 ◽  
Author(s):  
Amina A. Kamar ◽  
Noel Maalouf ◽  
Eveline Hitti ◽  
Ghada El Eid ◽  
Hussain A Ismaeel ◽  
...  

Ever since the World Health Organization (WHO) declared the new coronavirus disease 2019 (COVID-19) as a pandemic, there has been a public health debate concerning medical resources and supplies including hospital beds, intensive care units (ICU), ventilators, and Protective Personal Equipment (PPE). Forecasting COVID-19 dissemination has played a key role in informing healthcare professionals and governments on how to manage overburdened healthcare systems. However, forecasting during the pandemic remained challenging and sometimes highly controversial. Here, we highlight this challenge by performing a comparative evaluation for the estimations obtained from three COVID-19 surge calculators under different social distancing approaches, taking Lebanon as a case study. Despite discrepancies in estimations, the three surge calculators used herein agree that there will be a relative shortage in the capacity of medical resources and a significant surge in PPE demand as the social distancing policy is removed. Our results underscore the importance of implementing containment interventions including social distancing in alleviating the demand for medical care during the COVID-19 pandemic in the absence of any medication or vaccine. It is said that ″All models are wrong, but some are useful″, in this paper we highlight that it is even more useful to employ several models.  


2020 ◽  
Vol 3 (2) ◽  
pp. 130
Author(s):  
Kelly Kelly ◽  
Lie Rebecca Yen Hwei ◽  
Gilbert Sterling Octavius

Since the beginning of 2020, the world has been affected by the novel coronavirus COVID-19 pandemic. The virus’ infectious nature pushed all sectors to implement social distancing measures in an effort to limit its transmission, including the education sector. We searched PubMed and Science Direct on June 12th and found 24 papers that are relevant to our review. After the World Health Organization announced that COVID-19 is a global threat, various countries took a variety of measures to limit the disease spread such as social distancing, self-quarantine, and closing public facilities that hold large gatherings, including universities and schools. Hospitals started to prioritize services for COVID-19 cases. Medical education programs are also affected by this disease, but not continuing in-person classes outweighs any benefit from traditional teaching methods. The previous Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) pandemics have shown ways to shift medical education to online platforms. In the current pandemic, online meetings are being used to hold lectures, classes, laboratory practices, and clinical skills classes. For clerkship students, online platforms might not be feasible because this eliminates patient-doctor relationships, but it appears for now to be the only option. Some institutions have involved medical students in the frontlines altogether. We encourage all parties to constantly evaluate, review, and improve the efforts of continuing medical education, especially during this pandemic. Further research is needed to evaluate students’ performance after adopting e-learning and to discover the best methods in medical education in general and clerkship education in particular.


2021 ◽  
Vol 24 (2) ◽  
pp. 173-177
Author(s):  
Abraham Cyril Issac

Abstract The world is battling out the pandemic of Covid-19. The World Health Organization (WHO) is jointly acting upon the same daily, which is evident from the ‘situation reports.’ The pandemic, which saw its origin in Wuhan, has spread across the world within a short span of under two months. While the pandemic has effectively instilled a situation of cordon sanitaire across the globe, the virus seems to show no respite. This study collates different sources and establishes the human tendency of knowledge hiding as the prime reason for the spread of such colossal magnitudes. The study underlines the notion by examining some of the critical cases and situations that have unfolded in the very recent past.


2020 ◽  
Vol 10 (3) ◽  
pp. 241-252
Author(s):  
Ruchi Jain ◽  
Nilesh Jain ◽  
Surendra Kumar Jain ◽  
Ram C Dhakar

The 2019-nCoV is officially called SARS-CoV-2 and the disease is named COVID-19. The Novel coronavirus (SARS-CoV-2) caused pneumonia in Wuhan, China in December 2019 is a highly contagious disease. The World Health Organization (WHO) has declared it as a global public health emergency. This is the third serious Coronavirus outbreak in less than 20 years, following SARS in 2002–2003 and MERS in 2012. Currently, the research on novel coronavirus is still in the primary stage. It is currently believed that this deadly Coronavirus strain originated from wild animals at the Huanan market in Wuhan by Bats, snakes and pangolins have been cited as potential carriers. On the basis of current published evidence, we systematically summarize the epidemiology, clinical characteristics, diagnosis, treatment and prevention of COVID-19. This review in the hope of helping the public effectively recognize and deal with the novel coronavirus (SARS-CoV-2) and providing a reference for future studies. Keywords: SARS-CoV-2, COVID-19, Coronavirus, pneumonia, Respiratory infection


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