scholarly journals Efficacy of Albendazole Against Strongylus sp. and Hematology Changes on Equine in Yogyakarta Special Region

2021 ◽  
Vol 39 (2) ◽  
pp. 130
Author(s):  
Yuriadi Yuriadi ◽  
Ida Tjahajati ◽  
Guntari Titik Mulyani ◽  
Kelviano Muqit ◽  
Aidah Rahmanita

The infestation of Strongylus sp. in horses can cause losses to horse breeders, including anorexia, anemia, gastrointestinal diseases and can cause death and decrease the horse population in DIY. Albendazole was a Benzimidazole preparation that is often used to treat worms in ruminants. This study also aims to determine the effect of Albendazole on blood images before and after treatment. The material used in this study were 10 horses with male and female sex,  over 3 years old, and infected with Strongylus sp. with an infestation rate of 200 EPG in faeces. Before treatment of drug was carried out, the faeces was examined with Mc Master method. After treatment with Albendazole, the worm eggs were examined three times at intervals of three days. Routine examination of worm eggs and blood was carried out at the Laboratory of the Department of Internal Medicine, Faculty of Veterinary Medicine, Universitas Gadjah Mada. The results showed that the EPG number decreased from the 0th, 3rd, 6th and 9th day of examinations. The average number of EPG on the 0th day was 990 eggs/gram, and the examination on the 9th day showed the number of eggs was 0 eggs/gram. The results of the hematology examination also showed no significant difference except for the high number of eosinophils on the 12th day after drug administration. The conclusion from this research is that Albendazole as a worm medicine can kill Srongylus sp. however, it does not affect the horse's hematology and health status.

Logopedija ◽  
2018 ◽  
Vol 8 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Anđela Bučević ◽  
Ana Bonetti ◽  
Luka Bonetti

The aim of this research paper was to examine the voice quality of sports coaches using the objective (acoustic) method. A total of 28 sports coaches (mean age 28.58, SD=5.08), from the City of Zagreb participated in this research. Recordings of the phonation of the vowel /a/ before and after one training session were obtained and analyzed using the PRAAT Program. Mean, minimal and maximal values of fundamental frequency, shimmer, jitter and harmonics-to-noise ratio were observed. The statistical analyses showed no statistically significant difference in acoustic voice quality of male and female coaches before and after the training session, or between male and female coaches. However, intra-individual differences among participants were observed, which may be significant in terms of their potential to affect the quality of their voices in the future.


2008 ◽  
Vol 20 (3) ◽  
Author(s):  
Samuel Setiawan ◽  
Edeh Rolleta Haroen ◽  
Dede Hadidjah

In administering fluoride through drinking water there is the risk of overdose, higher cost and inadequate availability of drinking water containing fluoride in developing countries like Indonesia. A safe fluoride source is contained in toothpaste. The purpose of this research was to obtain data concerning difference in saliva pH before and after brushing with toothpaste containing fluoride and without toothpaste. The research method used was the quasi-experimental method. Samples were collected by the way of purposive sampling, conducted on 43 male and female research subjects. The data were analyzed by statistical analysis using the t test at 95% confidence level. In this research a control group consisting of 43 people was used. Research results indicated that the average saliva pH before brushing was 7.174; after brushing with fluoride containing toothpaste salivary pH was 7.593. Result research of brushing without toothpaste showed an average saliva of 7.163 before brushing and 7.379 after brushing without toothpaste. The average changes in saliva pH before and after brushing using fluoride containing toothpaste was 0.216. The conclusion of this research was that there was significant difference in saliva pH before and after brushing with toothpaste containing fluoride; there was significant difference in saliva pH before and after brushing without toothpaste, and there was significant difference in saliva pH before and after brushing with toothpaste containing fluoride and without toothpaste.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Rahele Hassanpour Moghaddam ◽  
Fatemeh Nazemian ◽  
Sedigheh Rastaghi ◽  
Mostafa Rad

Background: The present study aimed to evaluate the effect of cold dialysis solution on the sexual dysfunction of patients with chronic renal failure undergoing hemodialysis. Methods: This randomized clinical trial was conducted with a before and after parallel design among 60 hemodialysis patients diagnosed with sexual dysfunction. The selected subjects were randomly allocated to the two groups of experimental and control (30 per each). Patients in the experimental and control groups underwent hemodialysis for one month using 35.5°C and 37°C dialysis solutions, respectively. Following the procedure, male and female sexual function was assessed in the study groups. Data were collected using the International Index of Erectile Functions, the female sexual function index (FSFI), and a demographic questionnaire. Data analysis was performed using Chi-square, Fisher's exact test, Mann-Whitney U test, t-test, paired t-test, and Wilcoxon test at 95% confidence interval. Results: No significant difference was observed between the experimental and control groups regarding male sexual function before and after the intervention (P > 0.05). However, the Mann-Whitney U test indicated a significant difference in the female subjects’ arousal in the experimental group before (3.68 ± 0.38) and after the intervention (3.98 ± 0.46; z = 2.216; P = 0.027). Conclusions: Cold dialysis solution could only increase the sexual arousal of the women in the experimental group, and no changes were observed in other sexual function domains of the male and female patients. Given the short duration of our intervention, it is recommended that further longitudinal studies be performed on larger cohorts of patients in different geographical regions.


2021 ◽  
pp. 10-10
Author(s):  
Mario Ostovic ◽  
Tomislav Mikus ◽  
Velimir Susic ◽  
Kristina Matkovic ◽  
Zeljko Pavicic ◽  
...  

Research into the veterinary perception of animal welfare is becoming ever more relevant. Following previous studies on Croatian veterinary students? attitudes and opinions towards farm animal and pet welfare, the present study assessed their attitudes towards sheep and goat welfare, focusing on the year of veterinary medicine study and area of student residence. The questionnaire survey involved students of all six years of the integrated undergraduate and graduate study programme at the Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia. First-year students filled out the questionnaire twice, before and after having attended the animal welfare subject. The questionnaire consisted of two sections. The first section included questions on student demographic and experiential characteristics, whereas the second section asked them to define the level of cognition, sentience and welfare compromise in sheep and goats through five-point Likert scale questions. Study results revealed that students agreed that sheep and goats have cognitive abilities and feelings, but they neither agreed nor disagreed about their welfare compromise. There was no significant difference in student responses according to years of study or between first-year student responses before and after having attended the animal welfare subject or according to areas of student residence. These results could suggest poor student interaction with small ruminants and, therefore, help expand the respective curriculum.


2020 ◽  
Vol 51 (3) ◽  
pp. 281-292
Author(s):  
Magdalena Palić ◽  
Vesna Matijatko ◽  
Filip Kajin ◽  
Iva Šmit ◽  
Marin Torti ◽  
...  

Hypoadrenocorticism arises from insufficient adrenal gland function and is also known as Addison’s disease, a rarely occurring disease (0.1%) in dogs. Due to its oscillatory course and overall nonspecific symptoms, it is a diagnostic challenge for clinicians, and is often misdiagnosed or unattended among other differentials. There are two forms of hypoadrenocorticism: primary and secondary. The aim of this study was to analyse the data of dogs suffering from Addison’s disease, treated at the Clinic for Internal Medicine, Faculty of Veterinary Medicine, University of Zagreb, Croatia and to compare them with data from similar institutions worldwide. The archive of Clinic for Internal Medicine, Faculty of Veterinary Medicine, Zagreb, Croatia was searched to investigate and statistically analyse signalment, clinical and laboratory data, and the duration of symptoms, treatment protocols and outcome of canine hypoadrenocorticism. The study group included 14 dogs (36% male and 64% female) diagnosed with hypoadrenocorticism. All dogs had a history of gastrointestinal symptoms, i.e. vomiting in 100%, diarrhoea in 64% and melena in 7%. Hypovolemic shock was noted in 57%, hypothermia in 64% and bradycardia in 29% of cases. The most frequently observed laboratory abnormalities were an increase in BUN (86%), creatinine (57%) and potassium concentration (79%), and a decrease in sodium (71%), Na/K ratio (86%), cholesterol (21%) and glucose concentration (21%). Duration of symptoms (till ACTH stimulation test performance) was broad, from 2 – 2190 days (median 90±1195.5 days). The outcome was favourable in 100% cases after initiation of adequate treatment.


2018 ◽  
Vol 26 (2) ◽  
pp. 280-287
Author(s):  
Elena V. Filatova ◽  
Khajimurat M. Malayev ◽  
Oleg E. Konovalov

Aim. To identify specificity of reaction of a male and female organism to galvanic mud application procedures in cervicalgia. Materials and Methods. 48 Patients (23 men and 25 women) with the diagnosis of cervicalgia who took a course of rehabilitation treatment in Republican Hospital of Rehabilitation Treatment of Makhachkala, were examined. The patients received medicinal treatment and medical massage. Galvanic mud therapy was conducted with the underlying standard therapy. The effectiveness and safety of the procedure were evaluated using visual analog scale (VAS), and also parameters of the arterial pressure and heart rate before and after the procedure, and also values of Kerdo vegetative index, body mass index, mobility of the cervical part of the spine, psychoemotional condition by WAM test. Results. Analysis of predomination and characteristics of pain syndrome revealed predomination of the damage to the upper cervical parts (in women – 62.0%, in men – 40.0%), and statistically more common cervicocranialgias in women (22.0% against 8.0% in men). Headaches associated with pain in the neck were reliably more common in women than in men (48.0% and 10.0%, respectively). A significant difference in the rate of complaints of pain irradiation to the upper limbs was recorded (20.0% of women against 10.0% of men). Intensity of pain syndrome determined by VAS test significantly differed in the compared groups before rehabilitation (5.25±1.64 points in men and 5.62±1.98 points in women, р<0.05); after rehabilitation treatment VAS parameters decreased in both groups: in men down to 1.62±0.83 points (р<0.05), in women – to 2.25±1.07 points (р<0.05), here, no significant differences between the groups were found. In women with cervicalgias the distance between the upper and lower cervical vertebrae was on average 14.0±0.1 cm, increment on bending before treatment was 2.43±0.75 cm and after treatment 2.75±0.11 cm which indicates a tendency to normalization of the condition of muscle tissue, but preservation of spastic component. Conclusion. Mud therapy in complex rehabilitation of patients positively influences recovery of the motor activity of the cervical part of the spine.


2018 ◽  
Vol 26 (2) ◽  
pp. 280-287
Author(s):  
Elena V. Filatova ◽  
Khajimurat M. Malayev ◽  
Oleg E. Konovalov

Aim. To identify specificity of reaction of a male and female organism to galvanic mud application procedures in cervicalgia. Materials and Methods. 48 Patients (23 men and 25 women) with the diagnosis of cervicalgia who took a course of rehabilitation treatment in Republican Hospital of Rehabilitation Treatment of Makhachkala, were examined. The patients received medicinal treatment and medical massage. Galvanic mud therapy was conducted with the underlying standard therapy. The effectiveness and safety of the procedure were evaluated using visual analog scale (VAS), and also parameters of the arterial pressure and heart rate before and after the procedure, and also values of Kerdo vegetative index, body mass index, mobility of the cervical part of the spine, psychoemotional condition by WAM test. Results. Analysis of predomination and characteristics of pain syndrome revealed predomination of the damage to the upper cervical parts (in women – 62.0%, in men – 40.0%), and statistically more common cervicocranialgias in women (22.0% against 8.0% in men). Headaches associated with pain in the neck were reliably more common in women than in men (48.0% and 10.0%, respectively). A significant difference in the rate of complaints of pain irradiation to the upper limbs was recorded (20.0% of women against 10.0% of men). Intensity of pain syndrome determined by VAS test significantly differed in the compared groups before rehabilitation (5.25±1.64 points in men and 5.62±1.98 points in women, р<0.05); after rehabilitation treatment VAS parameters decreased in both groups: in men down to 1.62±0.83 points (р<0.05), in women – to 2.25±1.07 points (р<0.05), here, no significant differences between the groups were found. In women with cervicalgias the distance between the upper and lower cervical vertebrae was on average 14.0±0.1 cm, increment on bending before treatment was 2.43±0.75 cm and after treatment 2.75±0.11 cm which indicates a tendency to normalization of the condition of muscle tissue, but preservation of spastic component. Conclusion. Mud therapy in complex rehabilitation of patients positively influences recovery of the motor activity of the cervical part of the spine.


Author(s):  
Hande Peynirci

Background: The prevalence of obesity is gradually increasing worldwide and reaches an epidemic extent. Currently, treatment of obesity with pharmacological options has gained importance due to the frequent failure of lifestyle changes. Anti-obesity medications have an unfortunate history that make many clinicians uncomfortable with their prescription. In this study, we aimed to examine the effect of orlistat on weight loss and glycaemic parameters.Methods: Forty patients under orlistat treatment between November 2017 to October 2018 were recruited and their weight, body mass index (BMI), glucose, insulin, and the homeostatic model assessment of insulin resistance (HOMA-IR) values were recorded before and after treatment. Patients aged >18 years with BMI≥40 kg/m2 were enrolled to the study while having the diagnosis of diabetes mellitus, those with gastrointestinal diseases, who were pregnant or in lactation period, using drugs that have an effect on weight, and who did not come their follow-up after 12 weeks were excluded.Results: Thirty-four patients were female, 6 were male, and the mean age was 42.75±10.60 years. The mean height found as 161.10±8.98 cm. Before treatment, the mean weight was 120.62±16.56 kg, BMI was 46.43±4.61 kg/m2, and HOMA-IR was 5.84±3.58. After 12 weeks, it was observed that the mean weight decreased to 112.67±16.21 kg, BMI to 43.35±4.55 kg/m2, and HOMA-IR to 3.73±2.38. There was a statistically significant difference in these parameters compared to the pre-treatment values.Conclusions: Given the lack of non-surgical treatments, orlistat can provide significant benefits in the current clinical practice when combined with the appropriate diet.


2020 ◽  
Vol 13 (Suppl_1) ◽  
Author(s):  
Jordan L Gavin ◽  
Elizabeth Walters ◽  
Kevin J O'Leary

Background: Collaboration between cardiologists and internists is essential to providing safe, effective, and patient-centered cardiovascular care. The objective of this study was to determine the quality of collaboration between these clinicians during inpatient consultations and identify areas for improvement. Methods: We surveyed hospitalists, general internal medicine faculty, and resident physicians from inpatient general medicine services and consulting cardiology attendings and fellows at a large tertiary care hospital over a two month period. Respondents were asked to rate each other’s level of collaboration on a 5-point ordinal response scale and answer multiple choice and free-response questions on consultation practices and personal preferences. Results: Overall, 92 of 155 (59%) eligible hospitalists, general internal medicine faculty, and resident physicians completed the primary survey. Collaboration with cardiology consultants was rated as high or very high quality by 72% of respondents. There was no significant difference between ratings of collaboration quality based on respondents’ level of training. Internists identified resistance or disagreement with indication for consultation, difficulty receiving a timely response, and poor follow-up communication as the largest barriers to high quality collaboration. Most internists preferred receiving recommendations by page, phone, or written in a consult note, rather than in person. Internists appreciated close communication throughout the consultation process. For longitudinal consultations, internists preferred when an intention to sign-off was communicated by page or wrote in that day’s consult note. In total, 9 cardiology attendings and fellows completed the specialty survey. Cardiologists reported providing recommendations the same day for routine consultations, or within 2-3 hours when urgent. Most consultants communicated their recommendations thru page, phone conversations, or written consult note. Providing recommendations in person was rare. Half of cardiology attendings and fellows rated collaboration with internists as high or very high quality. There was no significant difference between their ratings of collaboration with hospitalists and residents. Cardiologists appreciated when outside hospital records had already been obtained. They identified receiving an unclear reason for consult, consulting prior to initial work-up, late in the day, or when an outpatient appointment was more appropriate as the largest barriers to high quality collaboration. Conclusions: While cardiologists and internists appear to agree on modes of communication, they have different perceptions of timeliness and disagreements on appropriateness of consultations. Further research is needed to design and study interventions that address these barriers to high quality collaboration.


Author(s):  
R. F. Bils ◽  
W. F. Diller ◽  
F. Huth

Phosgene still plays an important role as a toxic substance in the chemical industry. Thiess (1968) recently reported observations on numerous cases of phosgene poisoning. A serious difficulty in the clinical handling of phosgene poisoning cases is a relatively long latent period, up to 12 hours, with no obvious signs of severity. At about 12 hours heavy lung edema appears suddenly, however changes can be seen in routine X-rays taken after only a few hours' exposure (Diller et al., 1969). This study was undertaken to correlate these early changes seen by the roengenologist with morphological alterations in the lungs seen in the'light and electron microscopes.Forty-two adult male and female Beagle dogs were selected for these exposure experiments. Treated animals were exposed to 94.5-107-5 ppm phosgene for 10 min. in a 15 m3 chamber. Roentgenograms were made of the thorax of each animal before and after exposure, up to 24 hrs.


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