scholarly journals PHYTO-PHARMACOLOGICAL PROPERTIES OF SIDA CORDIFOLIA: A REVIEW OF FOLKLORE USE AND PHARMACOLOGICAL ACTIVITIES

Author(s):  
Navneet Khurana ◽  
Neha Sharma ◽  
Shailendra Patil ◽  
Asmita Gajbhiye

<p>ABSTRACT<br />Plants have been considered to be useful as a medicine for treating different ailments and improving health conditions, since ancient times. The<br />plants as herbal drugs lay down an important foundation of different, well recognized, ancient, and traditional healthcare systems in India as well as<br />other parts of the world. In India, plants constitute an important and indispensable role in different ancient healthcare systems such as Ayurveda,<br />Siddha, Unani, Naturopathy, and Homeopathy. In Ayurveda system of medicine, one of the Rasayana plants having a great medicinal importance is<br />Sida cordifolia belonging to the family Malvaceae. It is an annual undershrub found throughout the tropical and subtropical regions of India. It has<br />been used since ancient times for various ailments in Ayurveda system of medicine. It has numerous folklore uses in different pathological conditions.<br />The plant also reported to possess a number of important pharmacological activities. The present review focused on all these folklore use of this herb<br />along with its reported pharmacological activities.<br />Keywords: Sida cordifolia, Ayurveda, Parkinson’s disease, Analgesic, Anti-inflammatory.</p>

Author(s):  
Pushpa Anantrao Karale ◽  
Mahesh A Karale

  Calotropis procera and Gymnema sylvestre are a perennial shrub and woody climber, respectively, and belonging to the family Asclepiadaceae. They are commonly known as milkweed family herbs. The Calotropis commonly have two species, i.e., C. procera and C. gigantean. All parts of plant exude white milky latex when cut. It has been widely used in traditional medicine due to its pharmacological active compounds found in all parts of plants such as bark, roots, and leaves and especially its latex which exudes from damaged or broken stem and leaves. G. sylvestre an ayurvedic herb came to be known as “destroyer of sugar” because in ancient times Ayurveda physicians observed that chewing a few leaves of G. sylvestre suppressed the taste of sugar. It also reported to possess antidiabetic, antioxidant, and immunomodulatory, antiulcer, and anticancer potential. The gymnemic acid is the main constituent which is responsible for number of pharmacological activities. The present review assembles the data on pharmacognostic and pharmacological potential of C. procera and G. sylvestre.  


2021 ◽  
Author(s):  
Mohammed Ali

BACKGROUND cardiovascular diseases (CVDs) have become prevalent in the world. They cause millions of deaths globally with the World Health Organization putting the figure at 17.9 million people every year. These statistics indicate the need for healthcare systems to leverage contemporary advanced technology to detect and diagnose CVDs and provide appropriate and timely care to reduce mortality rates. OBJECTIVE To conduct a scoping review exploring individual use of smartwatches with self-monitoring ECG functionality for diagnosing arrhythmias. METHODS Source were selected from six credible bibliographic databases: PubMed, Medline, EMBASE, PsycInfo, CINAHL, and Google Scholar. Intervention-related terms were used to identify relevant sources. Additionally, a forward search strategy was used to search the databases and identify appropriate peer-reviewed journals. RESULTS The research returned 230 sources, out of which 40 met the inclusion criterion. The studies revealed that increased research, development, and adoption of smartwatches and other wearable devices have intensified in the past two decades. The studies showed that using smartwatches can detect cardiac arrhythmias although this depends on the algorithms and biometric sensors utilized in the smartwatches. Watches with advanced algorithms, PPG, and EKG functionalities exhibit high accuracy, sensitivity, and specificity, detecting AFib and other arrhythmias with high efficacy. Therefore, the best way for technology companies to improve their watches’ accuracy is to design and use advanced algorithms and combine PPG, EKG, activity, and biochemical sensors. Conclusion: The contemporary healthcare space is replete with wearable and non-wearable ¬systems and devices central to detecting health conditions and informing the relevant stakeholders to take corrective actions. Smartwatches are wearable devices used chiefly by patients, health, and fitness enthusiasts to detect and monitor a series of conditions, such as heart rate. Their use has fostered timely detection of cardiac arrhythmias, and therefore, caregivers and policy-makers should emphasize their use. CONCLUSIONS Technological systems have proliferated many human spaces in the last three decades, including education, healthcare, and entertainment. Their use has improved operational efficiency, reduced costs, saved lives, and increased organizations’ bottom lines. Healthcare systems use technological devices and appliances to diagnose patients, perform surgeries, improve pharmacy operations, and reduce medical errors. That way, most healthcare facilities provide quality care, attaining positive clinical outcomes. The contemporary healthcare space is replete with wearable and non-wearable ¬systems and devices central to detecting health conditions and informing the relevant stakeholders – caregivers, patients, and family members – to take corrective actions. Smartwatches are wearable devices used chiefly by patients, health, and fitness enthusiasts to detect and monitor a series of conditions, such as heart rate. They are highly effective in detecting cardiac arrhythmias, and therefore, caregivers and policy-makers should emphasize their use.


Author(s):  
Cheng-Peng Sun ◽  
Zi-Li Jia ◽  
Xiao-Kui Huo ◽  
Xiang-Ge Tian ◽  
Lei Feng ◽  
...  

As a genus of the Asteraceae, Inula is widely distributed all over the world, and several of them are being used in traditional medicines. A number of metabolites were isolated from Inula species, and some of these have shown to possess ranges of pharmacological activities. The genus Inula contains abundant sesquiterpenoids, such as eudesmanes, xanthanes, and sesquiterpenoid dimers and trimers. In addition, other types of terpenoids, flavonoids, and lignins also exist in the genus Inula. Since 2010, more than 300 new secondary metabolites, including several known natural products that were isolated for the first time from the genus Inula. Most of them exhibited potential bioactivities in various diseases. The review aimed to summarize the advance of recent researches (2010–2020) on phytochemical constituents, biosynthesis, and pharmacological properties of the genus Inula for providing a scientific basis and supporting its application and exploitation for new drug development.


2022 ◽  
pp. 179-194
Author(s):  
Sandeep Kumar ◽  
Ahmad Hussain ◽  
Manish Singh Sansi ◽  
Daraksha Iram ◽  
Priyanka ◽  
...  

The medicinal plants have been used by humans since ancient times, and the great civilizations of the world in ancient times were well aware of the benefits brought by the use of medicinal plants. This chapter provides important information regarding medicinal plants that have a wide variety of antioxidative agents ranging from bitter compounds that stimulate digestion system, phenolic compounds for antioxidant and numerous other pharmacological properties, antibacterial, and antifungal to tannins that act as natural antibiotics, diuretic substances, alkaloids, and so forth.


2021 ◽  
Vol 12 (2) ◽  
pp. 1496-1505
Author(s):  
Hartati R ◽  
Insanu M ◽  
Mudrika S. N. ◽  
Fidrianny I

The lemon plant (Citrus limon L.) is a species from the Rutaceae family that spread from Southeast Asia and spread to all countries in the world. Lemon has been used traditionally since ancient times to treat various diseases and has been tested for various pharmacological activities. The literature review was carried out to study the phytochemical compounds and pharmacological activities of lemon plants. The literature compiled by a minimum of 50 scientific articles using search engines such as Science Direct, Pubmed, and Google Scholar, published for a maximum of the last 10 years, includes a minimum of 20 articles in the last 2 years, has a DOI, and the quality of the journal index is reviewed using Scimago. Lemon is very rich in phytochemical compounds, including flavanones such as hesperidin, eriocytrin, naringin, narirutin, didymin; flavones such as apigenin, luteolin, and diosmin; flavonols such as routine, quercetin, mirisetin, isositrol, limositrol, and limositrin; terpenoids such as limonene, limonoids, and carotenoids. Various kinds of in vivo and in vitro studies provide results of various pharmacological activities such as antioxidants, anticancer, neuroprotective, antimicrobial, antidiabetic, anti-inflammatory, antihyperlipidemic, antiurolithiasis, and antiplasmodial. It is necessary to develop further research on the pharmacological activity of lemon plants in the future.


Author(s):  
Pragati Khare ◽  
Kamal Kishore ◽  
Dinesh Kumar Sharma

Objective: In today’s scenario, the herbal medicines are much efficient for the treatment of various disorders as they have minimal side effects incomparison to the allopathic medicines. Bauhinia variegata L. (Mountain Ebony), commonly called Kachnar, belongs to the family Leguminosae.It is a medium-sized tree, mostly found at an altitude of 1300 m in the Himalayas. The objectives of the present study are to investigate variouspharmacognostic, phytochemical analysis, and pharmacological properties of B. variegata.Methods: The powdered drug was used for estimating the loss on drying, ash values, fluorescence studies, chemical tests, and extractive values.Macroscopic and microscopic studies were also performed.Results: The leaf microscopy revealed the presence of upper and lower epidermis, palisade tissue, well-developed vascular bundle. The fluorescencecharacteristics of leaf powder were studied both in visible light and ultraviolet light (254 nm and 365 nm) after treatment with various reagents.Kachnar is composed of carbohydrates, tannins, alkaloids, flavonoids, amino acid. It was reported that the total ash value was 8.15%. The acidinsoluble ash value was 5.5%.Conclusion: The main pharmacological activities of B. variegata are anthelmintic, antiulcer, antitumor, antimicrobial, antidiabetic, anti-inflammatory, antigoitrogenic, and hepatoprotective. The present investigation provides the information on its pharmacognostic, phytochemical analysis, andpharmacological properties.Keywords: Flavonoids, Kachnar, Alkaloids, Antioxidant, Leguminosae.


2021 ◽  
Vol 16 (12) ◽  
pp. 150-160
Author(s):  
T. Sharma ◽  
V. Khandelwal

Ever since ancient times, medicinal plants served as a great source of herbal formulations which can confer human civilization with preferential quality of life. Among them, some plants secured their position in mythologies, also highlighting Anthocephalus cadamba, a religious medicinal plant, belonging to the family Rubiaceae, mostly cultivated in tropical regions. Conventional medicinal system of India provides evidences regarding folk medicinal uses for the treatment of various ailments like inflammation, skin diseases, uterine complaints, blood disease and diarrhea etc. Phytochemical investigations revealed the presence of some biologically active compounds like flavonoids, alkaloids, coumarins, terpenoids, diterpenoids, triterpenes, glycosides, sterols, amides and fatty acids and these compounds were found to be accountable for various pharmacological activities such as antimicrobial, antipyretic, anti-inflammatory, analgesic, anticancerous, antidibetic, hypolipidemic, antihepatotoxic, antidiarrhoel, diuretic, laxative, antioxidant, immunomodulatory, wound healing etc.


Author(s):  
LALITA BATTASE ◽  
DAKSHA ATTARDE

Lantana camara is a plant from the family - Verbenaceae. It is found in many states of India, mostly in Jammu-Kashmir, Himachal Pradesh, Tamil Nadu, South India, Uttar Pradesh, and several parts of Maharashtra and other countries also. Mainly in disturbed areas, including roadside, railway tracks, and canals. It is an ornamental plant but, in ancient times, it was used traditionally. The plant having various traditional uses. Parts of plant extracts are used traditionally such as the healing of wounds, cuts, skin itches, and eczema. The plant containing many more phytoconstituents such as alkaloids, glycosides, saponins, steroids, terpenoids, carbohydrates, flavonoids, and coumarins. It has various pharmacological activities antioxidant, antimicrobial, antibacterial, antifungal, antiulcerogenic, anthelmintic, anti-hyperglycemic, anti-inflammatory, analgesic, anticancer, antitubercular, etc. It also having mosquito larvicidal activity. This review article was written by the study of many research and review articles from 1956 to March 2021 in which 72 articles were cited. This article reviewed different phytochemicals present in L. camara. The review draws attention to the traditional uses, analytical work, pharmacological activities, and toxicology of this plant and also the potential uses of this plant.


2021 ◽  
Vol 24 (12) ◽  
pp. 2085-2088
Author(s):  
G.F. Kontagora ◽  
N. Lawal ◽  
D.A. Adebote ◽  
B. Kamba ◽  
M.I. Nafiu ◽  
...  

Borreria vertcillata is a woody perennial shrub with false-button weedy herb belonging to the family (Rubiaceae), used for treating/curing various forms of diseases across the world since ancient times. Qualitative phytochemical screening of Borreria vertcillata pulverized whole plant was carried out using four different solvent extracts (N-hexane, chloroform, ethyl-acetate and methanol). The phytochemicals screeened contained alkaloids, triterpenes, flavonoids, glycosides, tannins, saponnins, anthraquinones and steroids. The extracts were then screened for the presence of some phytochemicals such as alkaloids, anthraquinones, saponnins, steroids, terpenes, flavonoids, tannins and glycosides. All the extracts contained alkaloids, triterpenes and glycosides present but flavonoids, saponnins and tannins only present in ethyl acetate and methanol while anthraquinones and steroids were totally absent from the extracts .Of all the extracts Ethyl acetate extracts had the most influential effects on pathogenic organisms such as Culex quinquefasciatus, Staphylococcus aureus, Escherichia coli and Candidas albican


2019 ◽  
Vol 17 (2) ◽  
pp. 97-130
Author(s):  
Miljana Djordjevic ◽  
Niko Radulovic

This review summarizes current knowledge concerning the isolation, structural elucidation, biological/pharmacological activities, and total synthesis of halogen-containing secondary metabolites isolated from ascidians of the family Didemnidae. Overall, 81 compounds are presented, displaying great structural diversity and possessing a number of significant biological/pharmacological properties. In addition to the most numerous brominated compounds, chlorinated and iodinated ones were also found. The most prolific genus in regard to the number of published papers and isolated molecules is the genus Didemnum, which was treated separately from the rest of the genera of the ascidian family. The structural complexity of the isolated metabolites prompted a number of synthetic endeavors that not only provided conclusive proof of the structure of the metabolites but also enabled the biological tests and the possible application of these metabolites.


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