scholarly journals Accidental Closantel Poisoning in Sheep in the State of Rio Grande do Sul - Brazil

2020 ◽  
Vol 48 ◽  
Author(s):  
Camila Blanco Pohl ◽  
Marina Paula Lorenzett ◽  
Bianca Santana de Cecco ◽  
Luan Cleber Henker ◽  
Welden Panziera ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Histopathological Examination ◽  
Safety Margin ◽  
Clinical Signs ◽  
Plexiform Layer ◽  
Rio Grande ◽  
Clinical History ◽  
Final Diagnosis ◽  
Rio Grande Do Sul ◽  
Photoreceptor Layer

Background: Verminosis is one of the major health problems in sheep flocks, and is one of the main causes of death in sheep worldwide. Closantel is an antiparasitic drug commonly used in sheep; however, its safety margin is narrow, and this drug may induce intoxication in animals submitted to high doses. Lesions occur mainly in the eyes, and are characterized by edema and compression of the optic nerve, retinopathy, and severe degeneration of ganglia cells. Clinical signs are pupil dilation, which often lead to permanent blindness. This work aims to report an outbreak of sheep mortality due to closantel intoxication, associated with inadequate anthelmintic administration practices.Case: An on-site visit was conducted to a sheep farm, located in the municipality of Osório, Rio Grande do Sul (RS), in which high mortality was reported. The flock consisted of approximately 300 Texel sheep, managed in an extensive grazing system. Lambs and adult animals were affected. According to the information provided by the farm owner, many animals presented clinical signs of haemonchosis, and a closantel dose of 20 mg / lamb was administered in all sheep, regardless of body weight. Lambs weighted on average 13 kg. After closantel administration, several sheep presented neurologic signs and died.  At the clinical examination, sheep presented pallor of ocular mucous membranes, as well as submandibular edema.  Also, 20 lambs showed signs of blindness, disorientation and bumping into objects, as well as hypothermia and lack of response to the menace reflex. Three 30 to 45-day-old male lambs that died spontaneously were submitted for necropsy. Grossly, only mild ascites was noted. Histopathological examination of the retina showed degeneration and fragmentation of photoreceptor layer as well as depletion of the inner nuclear layer, associated with pyknosis and karyorrhexis. There was also a reduction in the number of ganglia cells in the ganglion cell layer and atrophy and vacuolization in the outer plexiform layer. In the optic nerve, multifocal mild to moderate vacuolization was observed.  Diffuse perineural and perivascular edema were observed in the brain, predominantly in the grey matter. In the encephalon of one of the lambs, multifocal vacuolization was observed, which was also evidenced at the junction of the white and gray matter of the telencephalon, and in the white matter of the cerebellum. In the trigeminal ganglia, moderate multifocal vacuolization was noted in the perikaryon of neurons. Furthermore, the spinal cord had moderate multifocal vacuolization at the junction of white and gray matter.Discussion: The diagnosis of closantel intoxication in sheep was based on the clinical history and histopathological findings. The association of these data is crucial to suspect and confirm the diagnosis of this type of intoxication. Closantel is an anthelmintic drug widely used in sheep, and in correct doses may be very effective, but when used in doses higher than recommended may lead to irreversible lesions.  The optical damage is derived from edema which leads to degeneration of ganglia cells and injury to the optic nerve. Another proposed mechanism is related to optic nerve compression causing rupture and edema of retinal structures. Lesions tend to be dose related, and poisoning usually occurs when treating groups of animals based on the weight of the heaviest animal. Clinical signs of blindness and pupil dilatation are usually seen. There is no effective treatment for reversion of this condition; therefore, prevention based on correct calculation of anthelmintic dose is pivotal. The epidemiological examination, clinical signs and anatomopathological examination were extremely important to make the final diagnosis of this intoxication. 

scholarly journals Psoroptes ovis infestation of sheep in São Vicente do Sul, Rio Grande do Sul, Brazil

2020 ◽  
Vol 50 (10) ◽  
Author(s):  
José Osvaldo Jardim Filho ◽  
Gisane Lanes de Almeida ◽  
José Vitor Marcon Piazer ◽  
Luiza Jacondino Rodegheri ◽  
Nathálie Bonotto Ruivo ◽  
...  
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Histopathological Examination ◽  
Clinical Signs ◽  
Rio Grande ◽  
Skin Lesions ◽  
Rio Grande Do Sul ◽  
Psoroptes Ovis ◽  
Sheep Farm ◽  
Poor Nutritional Status

ABSTRACT: Sheep psoroptic mange is a form of highly itchy and contagious dermatitis caused by the mite Psoroptes ovis. Here, we reporteda case of sheep psoroptic mange outbreak at a property in São Vicente do Sul, Rio Grande do Sul (RS), Brazil. Poor nutritional status, restless behavior, pruritus, wool fall, yellowish crusted skin lesions with edge exudate, erythema surrounding the lesions and presence of wool trapped between the teeth were observed in the herd. Complete blood count test showed marked eosinophilia, and parasitological examination of a skin scrape revealed P. ovis. Histopathological examination of a skin biopsy sample revealed eosinophilic pustular dermatitis. The treatment consisted of two administrations of 1% ivermectin at 1 mL/33 kg of body weight subcutaneously over an interval of 10 days. To the best of our knowledge, this is the first report of the occurrence of psoroptic mange at a sheep farm of RS with description of the clinical signs and laboratory and histopathological findings.

scholarly journals Clinical, pathological and epidemiological aspects of outbreaks of bluetongue disease in sheep in the central region of Rio Grande do Sul

2017 ◽  
Vol 37 (12) ◽  
pp. 1443-1452
Author(s):  
Ronaldo M. Bianchi ◽  
Welden Panziera ◽  
Tatiane C. Faccin ◽  
Gisane L. de Almeida ◽  
Juliana F. Cargnelutti ◽  
...  
Keyword(s):  
Central Region ◽  
Striated Muscle ◽  
Clinical Signs ◽  
Rio Grande ◽  
Nasal Discharge ◽  
Rio Grande Do Sul ◽  
Sample Collection ◽  
Area At Risk ◽  
Tissue Samples ◽  
Facial Swelling

ABSTRACT: This article describes the clinical, pathological and epidemiological aspects of 17 outbreaks of bluetongue (BT) disease in sheep occurring between December 2014 and July 2015 in the central region of Rio Grande do Sul state (RS), southern Brazil. Affected farms were visited for clinical examination, necropsy, sample collection and epidemiological investigation. The outbreaks were seasonal and occurred during the summer and autumn. A total of 180 sheep (20.4%) out of 884 in 17 small herds were affected. All ages of Texel and mixed breed sheep were affected. However, lambs (younger than one year) had higher morbidity than adult sheep. The most frequent clinical signs were anorexia, lethargy, loss of body condition, facial swelling mainly involving the lips, and greenish seromucous or mucous nasal discharge. Pulmonary lesions characterized by edema were the most prevalent findings; however, erosive and ulcerative lesions in the upper gastrointestinal tract, as well as cardiac, skeletal muscle and esophageal striated muscle necrosis, and hemorrhage in the pulmonary artery were also frequent. The bluetongue virus (BTV) genome was detected by RT-PCR in blood and tissue samples (spleen and lungs) of 21 animals from 17 outbreaks. The virus involved in the outbreak 3 was subsequently isolated and shown to belong to serotype 17, for the first time reported in Brazil. In summary, our data support the BTV genotype 17 as the etiological agent of the outbreaks and indicate that the central region of RS is an area at risk for BT in sheep, a disease previously not recognized in the region.

scholarly journals Poisoning by Senecio brasiliensis in Horses in Northern Rio Grande do Sul

2019 ◽  
Vol 47 ◽  
Author(s):  
Stéfano Leite Dau ◽  
Tanise Policarpo Machado ◽  
Ezequiel Davi Dos Santos ◽  
Diorges Henrique Setim ◽  
Eduardo Rebelato Sakis ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Weight Loss ◽  
Pyrrolizidine Alkaloid ◽  
Clinical Signs ◽  
Rio Grande ◽  
Type Ii ◽  
Post Mortem ◽  
Rio Grande Do Sul ◽  
Proprioceptive Deficit ◽  
Northern Rio Grande

Background: In various regions of Brazil, horses and cattle are considered the most susceptible animals to plant poisoning. The plants of the genus Senecio are the most important in Rio Grande do Sul because they have the active principle known as the pyrrolizidine alkaloid. Its diagnosis is made through epidemiology, clinical signs and histopathological analysis, either of the tissues obtained by biopsy or necropsy. The objective of this study was to report and characterize the epidemiological, clinical and anatomopathological findings of three cases of natural poisoning by Senecio brasiliensis in horses assisted at the Hospital Veterinário (HV) of the Universidade de Passo Fundo (UPF).Cases: Three traction horses, two males and one female, were admitted at the HV-UPF for clinical care. The animals were presenting anorexia, weight loss, dysmetria, proprioceptive deficit and signs suggestive of colic. The epidemiological study revealed that the sites where these animals were located were infested by Senecio brasiliensis. The support therapy used for equine colic in all three cases was unsuccessful. One of the animals died and the other two were euthanized, all three of them being reffered for necropsy. The post-mortem findings were mainly found in the liver, which showed accentuation of the lobular pattern and the appearance of nutmeg. During necropsy, fragments of organs from thoracic and abdominal cavities and central nervous system were collected and fixed in 10% buffered formalin. Subsequently, the samples were processed chemically, submitted to cuts of five micrometers of thickness and stained with hematoxylin and eosin for microscopic analysis. Microscopically, the liver of all three horses presented megalocytosis, fibrosis and bile ducts hyperplasia. In the central nervous system, spongiosis and the presence of Alzheimer type II astrocytes were observed. Thus, through the association of information, the diagnosis of poisoning by Senecio brasiliensis was achieved.Discussion: The diagnosis of natural poisoning by Senecio brasiliensis was obtained through the epidemiological survey that showed S. brasiliensis in pastures where all three horses were allocated.  Cases of intoxication by S. brasieliensis in cattle are more frequent than in equines, although both species are considered the most susceptible. In horses, the main clinical manifestations observed include neurological disorders, apathy, anorexia, dysphagia, weight loss, subcutaneous edema and icterus. The clinical signs presented by the equines suggested initial signs of colic syndrome, although anorexia, weight loss, dysmetria and proprioceptive deficit are commonly observed in pyrrolizidine alkaloid poisoning in the liver, both in cattle and horses. The pyrrolizidine alkaloids present in the genus Senecio that become toxic when biotransformed in the liver into a pyrrholic form highly reactive that inhibits cell mitosis and leads to the onset of megalocytosis, cell death and liver fibrosis. The necropsy findings and histopathology were characteristic of poisoning in equines, since the predominant macroscopic lesions in the liver were hepatomegaly and accentuation of lobular pattern, whereas microscopically, there was a predominance of hepatic fibrosis, megalocytosis, spongiosis and the incidence of Alzheimer's type II astrocytes in the brain. These lesions are observed both in natural and in experimental cases of poisoning in horses. Thus, through the ante-mortem and complete post-mortem evaluation of the three equines, it was possible to establish the occurrence of natural poisoning by Senecio brasiliensis in Northern Rio Grande do Sul, as well as to characterize the epidemiological, clinical and anatomopathological findings of poisoning in this species.

scholarly journals Postweaning multisystemic wasting syndrome in farmed wild boars (Sus scrofa) in Rio Grande do Sul

2006 ◽  
Vol 26 (3) ◽  
pp. 154-156 ◽  
Author(s):  
André Mendes Ribeiro Corrêa ◽  
Priscila Zlotowski ◽  
Daniela Bernadete Rozza ◽  
Mauro Riegert Borba ◽  
Juliano de Souza Leal ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Clinical Signs ◽  
Rio Grande ◽  
Postweaning Multisystemic Wasting Syndrome ◽  
Lymphoid Tissues ◽  
Rio Grande Do Sul ◽  
Wild Boars ◽  
Wasting Syndrome ◽  
Gross Lesions ◽  
Swine Disease

This report concerns an outbreak of postweaning multisystemic wasting syndrome in wild boars from commercial herds in Rio Grande do Sul, Brazil. The main clinical signs were progressive wasting, respiratory distress, diarrhea, and ocular discharges. Enhanced lymph nodes and spleens, ascites, hydrothorax, and non collapsed lungs were the principal gross lesions. Varying degrees of lymphohistiocytic infiltrates in lymph nodes, spleen, and intestines were the most significant microscopic changes. Although a total of 26 animals had showed clinical and pathological findings consistent with the disease, only in 11 of them it was possible to confirm a PMWS diagnosis through the association of specific lesions in lymphoid tissues with the presence of the viral antigen detected by immunohistochemistry. These findings were similar to those reported in the swine disease.

scholarly journals Prevalência de oxiuríase em equinos do Centro Hípico do 3º Regimento de Cavalaria de Guarda do Exército Brasileiro*

2020 ◽  
Vol 3 (4) ◽  
pp. 112-118
Author(s):  
Sybele Lima Mello ◽  
◽  
Sandra Márcia Tietz Marques ◽  
Carolina Rigotto Murari ◽  
Mary Jane Tweedie Mattos ◽  
...  
Keyword(s):  
Hair Loss ◽  
Clinical Signs ◽  
Rio Grande ◽  
Adhesive Tape ◽  
Rio Grande Do Sul ◽  
Perianal Region ◽  
Porto Alegre ◽  
The Third ◽  
Exercise Regimen ◽  
Tail Hair

The objective of this study was to determine the prevalence tax of Oxyuris equi and concomitant clinical signs in horses of the Equestrian Center of the Third Regiment of Guard Cavalry in Porto Alegre, Rio Grande do Sul. Between August and October of 2017, 93 sport horses were evaluated, of variable races, with individual stalls and exercise regimen with various intensities. The evaluated variables were: general condition of the fur coat and tail, of the perianal region and imprint of the perianal region with adhesive tape throughout Graham’s method. The prevalence tax was 25,81% (24/93) and it related to clinical signs of opaque fur coat and tail hair loss in 10,75% (10/93) and with the presence of egg masses of in 2,15% (2/93).

scholarly journals Epidemiological characterization of Leishmaniasis in the rural area of the western border region of Rio Grande do Sul, Brazil

2021 ◽  
Author(s):  
Gabriela Döwich Pradella ◽  
Claudia Acosta Duarte ◽  
Taiane Acunha Escobar ◽  
Luísa Zuravski ◽  
Geórgia Camargo Góss ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Rural Areas ◽  
Protective Factor ◽  
Descriptive Analysis ◽  
Clinical Signs ◽  
Rio Grande ◽  
Border Region ◽  
Rio Grande Do Sul ◽  
Western Border

Abstract Background: Leishmaniasis, zoonotic diseases, are in the top ten list of tropical neglected disease globally. The number of contaminated dogs in South America is estimated in millions of animals and correlated to the human’s cases, especially in Brazil. Equines became infected too and can play a role in the epidemiological chain. Thus, the aim of the present study was to evaluate risk factors to leishmaniasis in rural areas of the western border region of Rio Grande do Sul state, Brazil by Leishmania sp. protozoa molecular detection and serological evaluation (ELISA) in equine and canine blood samples. Methods: This work included nine farms around the city of Uruguaiana. It was collected epidemiologic information regarding farm characteristics and biologic material collection of canine and equine, totalizing 113 samples. The polymerase chain reaction (PCR) technique was used to detect Leishmania spp. in biological samples. Variables related to the farm were collected and evaluated through descriptive analysis followed by chi-square test and a logistic regression analysis.Results: Nineteen positive samples (19/113 – 16,81%) were detected, being 18 equines and 1 canine, in six of the nine farms included in the study. No animal showed clinical signs of the disease. According to the variables analyzed, when compared each characteristic separately, the presence of abundant vegetation and poor hygiene demonstrated to be risk factors to Leishmania infection in rural areas. The logistic regression showed that excellent general hygiene, proximity to the weir and trimmed grass were protective factors (p=0.038, p=0.001 and p=0.014, respectively). Having excellent hygiene represents a 70% lower chance of getting contaminated, keeping the grass cut protects the animal by more than 90% and the proximity of the weir represents a protective factor of 96%.Conclusions: The presence of leishmaniasis in the western border region of Rio Grande do Sul was 16,81% and it was influence by farm characteristics. The role of the excellent general hygiene as a protective factor is extremally relevant in the leishmaniosis prevention.

scholarly journals Outbreak of avian aspergillosis in colonial-bred chicks (Isa Brown) in southern Rio Grande do Sul - case report

2020 ◽  
Vol 72 (4) ◽  
pp. 1363-1368
Author(s):  
R. Zamboni ◽  
T.S. Alberti ◽  
H.V. Scheid ◽  
F.R. Venancio ◽  
C.B. Brunner ◽  
...  
Keyword(s):  
Clinical Signs ◽  
Rio Grande ◽  
Previous Treatment ◽  
Lung Parenchyma ◽  
Gallus Domesticus ◽  
Economic Losses ◽  
Gallus Gallus Domesticus ◽  
Rio Grande Do Sul ◽  
Avian Aspergillosis ◽  
Yellowish White

ABSTRACT In this study we describe the epidemiology, clinical signs, and pathology of an outbreak of avian aspergillosis in alternative breeding in the southern region of Rio Grande do Sul, Brazil. Between the fifth and tenth day of life, 360 chicks from a flock of 4000 developed unspecific clinical signs and died. The birds were housed in a reused aviary litter, without previous treatment. In 11 six-day-old female ISA Brown chicks (Gallus gallus domesticus), necropsy revealed firm, yellowish-white, multinodular lesions extending from the pleura to the lung parenchyma. Histologically, a granulomatous, multifocal to coalescent pneumonia was observed. Granulomas were characterized by central necrosis, with heterophil and epithelioid macrophage infiltration and presence of countless Y-shaped intralesional septate hyphae morphologically compatible with Aspergillus spp. The diagnosis through isolation confirmed Aspergillus fumigatus. We highlight the importance of aspergillosis as a primary cause of diseases in the respiratory tract of young birds in alternative breeding. Measures to prevent aspergillosis mainly regarding the reuse of aviary litter are essential in poultry husbandry to prevent economic losses, reduce environmental contamination and mitigate the potential risk to public health.

scholarly journals Histopathological and immunohistochemical findings of swine with spontaneous influenza A infection in Brazil, 2009-2010

2012 ◽  
Vol 32 (11) ◽  
pp. 1148-1154 ◽  
Author(s):  
Tatiane T.N. Watanabe ◽  
Laura L. de Almeida ◽  
Flademir Wouters ◽  
Angelica T.B. Wouters ◽  
Priscila Zlotowski ◽  
...  
Keyword(s):  
Influenza A ◽  
Swine Influenza Virus ◽  
Clinical Signs ◽  
Swine Influenza ◽  
Rio Grande ◽  
Histological Evaluation ◽  
Respiratory Syndrome Virus ◽  
Rio Grande Do Sul ◽  
Herd Health ◽  
Mato Grosso

Swine influenza (SI) is caused by the type A swine influenza virus (SIV). It is a highly contagious disease with a rapid course and recovery. The major clinical signs and symptoms are cough, fever, anorexia and poor performance. The disease has been associated with other co-infections in many countries, but not in Brazil, where, however, the first outbreak has been reported in 2011. The main aim of this study was to characterize the histological features in association with the immunohistochemical (IHC) results for influenza A (IA), porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) in lung samples from 60 pigs submitted to Setor de Patologia Veterinária at the Universidade Federal do Rio Grande do Sul (SPV-UFRGS), Brazil, during 2009-2010. All of these lung samples had changes characterized by interstitial pneumonia with necrotizing bronchiolitis, never observed previously in the evaluation of swine lungs in our laboratory routine. Pigs in this study had showed clinical signs of a respiratory infection. Swine samples originated from Rio Grande do Sul 31 (52%), Santa Catarina 14 (23%), Paraná 11 (18%), and Mato Grosso do Sul 4 (7%). Positive anti-IA IHC labelling was observed in 45% of the cases, which were associated with necrotizing bronchiolitis, atelectasis, purulent bronchopneumonia and hyperemia. Moreover, type II pneumocyte hyperplasia, alveolar and bronchiolar polyp-like structures, bronchus-associated lymphoid tissue (BALT) hyperplasia and pleuritis were the significant features in negative anti-IA IHC, which were also associated with chronic lesions. There were only two cases with positive anti-PCV2 IHC and none to PRRSV. Therefore, SIV was the predominant infectious agent in the lung samples studied. The viral antigen is often absent due to the rapid progress of SI, which may explain the negative IHC results for IA (55%); therefore, IHC should be performed at the beginning of the disease. This study has shown how important a careful histological evaluation is for the diagnosis. Since 2009, a new histological feature of swine pneumonia in animals with respiratory clinical signs has been observed in samples from pigs with clinical respiratory disease submitted to SPV-UFRGS. In addition, the results proved the importance of histological evaluation for swine herd health management.

scholarly journals Lily Poisoning in Domestic Cats

2018 ◽  
Vol 47 ◽  
Author(s):  
Welden Panziera ◽  
Claiton Ismael Schwertz ◽  
Luan Cleber Henker ◽  
Guilherme Konradt ◽  
Daniele Mariath Bassuino ◽  
...  
Keyword(s):  
Renal Failure ◽  
Rural Areas ◽  
Ornamental Plants ◽  
Clinical Signs ◽  
Clinical History ◽  
Final Diagnosis ◽  
Ventral Surface ◽  
Pathological Findings ◽  
Cell Degeneration ◽  
Mixed Breed

Background: Cases of plant intoxication in small animals are observed frequently in the domestic environment, mainly because most dogs and cats live in households and occasionally have access to streets and rural areas. Among such toxic agents, ornamental plants of the genus Lilium and Hemerocallis, which are potentially nephrotoxic to the feline species, are highlighted. Affected cats start presenting clinical signs 1-6 h after plant ingestion. Renal failure takes place in 12-72 h, and death may occur in an interval ranging from three to seven days. The objective of this article is to describe the epidemiological, clinical and pathological findings of lily (Lilium sp.) poisoning in two cats.Case: The aspects of lily poisoning in two cats are described (cat #1 and cat #2). Cat #1 was a 3-year-old, mixed breed female cat, which presented a clinical history of anorexia, apathy, drooling, vomiting and polydipsia. Serum biochemical analysis revealed creatinine elevation (21.2 mg/dL), as well as hyperphosphatemia (19 mg/dL). Seventy-two h after the onset of clinical signs, renal failure progressed to anuria, followed by death. The second animal of this report (cat #2) was a 2-year-old, mixed-breed male cat. The animal was found dead by the owner without displaying any previous clinical signs.  Cats #1 and #2 ingested leaves of lily, which were present in their households as ornamental plants. At necropsy, the kidneys of both cats presented mild enlargement. Moderate perirenal edema was also noted. Cat #1 showed morphologic extrarenal uremic lesions, characterized by ulcers in the oral mucosa and in the margin of the tongue ventral surface. Microscopic lesions observed in both cases were similar and compatible with acute toxic nephropathy. Histologically, severe epithelial cell degeneration and necrosis of proximal and distal convoluted tubules were noted. Other renal microscopic findings included hyaline and granular casts, tubule regeneration and occasional birefringent oxalate crystals. Cat #1 also presented moderate white matter vacuolation in the telencephalon and cerebellum.Discussion: The epidemiologic, clinical and pathological findings reported in the present study are similar to previous descriptions of lily poisoning in cats. Lily poisoning has been described in both males and females, without breed and age predisposition, similarly to what has been found in the present study. Kidney metabolite excretion, including the elimination of molecules such as creatinine, urea, and phosphorus is usually compromised in these cases, which was noted in cat #1. The same animal showed extrarenal manifestations of renal failure, leading to a clinical presentation of uremic syndrome, which is not frequent in these intoxications. Animals intoxicated by lily usually die from renal failure and anuria. In most cases, lesions are restricted to the kidneys. In the reported cases, the microscopical lesions consisted of tubule epithelial cells degenerative changes and necrosis. Acute lily intoxication in cats must be differentiated from other conditions, such as intoxications due to aminoglycoside antibiotics, heavy metals, nonsteroidal anti-inflammatory drugs, antifungal agents, chemotherapeutic drugs, and ethylene glycol. The knowledge regarding the toxic potential of ornamental plants is fundamental in order to prevent such events of intoxication, as well as to reach the final diagnosis. Epidemiological, clinical and pathological findings were essential to conclude the final diagnosis.

scholarly journals Rabies outbreak in buffaloes in Rio Grande do Sul, Brazil

2017 ◽  
Vol 47 (4) ◽  
Author(s):  
Ronaldo Michel Bianchi ◽  
◽  
Welden Panziera ◽  
Glauco José Nogueira de Galiza ◽  
Glaucia Denise Kommers ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Inclusion Bodies ◽  
Fluorescent Antibody ◽  
Clinical Signs ◽  
Rio Grande ◽  
Antibody Test ◽  
Definitive Diagnosis ◽  
Rio Grande Do Sul ◽  
Viral Antigens ◽  
Eosinophilic Inclusion

ABSTRACT: This report aimed to describe the clinical, epidemiological and pathological aspects of an outbreak of rabies in buffaloes in Rio Grande do Sul (RS), Brazil. Seven out of 41 buffaloes from the same farm became fatally ill; they showed the clinical signs of ataxia, ascending paresis, and paralysis of the limbs. During necropsy, marked hyperemia of the leptomeningeal vessels, and severe distention of the urinary bladder were noted. Histologically, there were indications of nonsuppurative meningoencephalitis and ganglioneuritis with intracytoplasmic and eosinophilic inclusion bodies in the neurons. The fluorescent antibody test was positive for rabies. Viral antigens were also detected by immunohistochemistry (IHC) in sections of the cerebellum. These results allowed for the definitive diagnosis of rabies, which is uncommonly reported in buffaloes.

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