scholarly journals Viral spot exants in children

2021 ◽  
Vol 13 (3) ◽  
pp. 19-29
Author(s):  
R. A. Ravodin ◽  
V. B. Rovnyi ◽  
Yu. S. Ermolaeva
Keyword(s):  
Infectious Diseases ◽  
Clinical Manifestations ◽  
Personal Archives

The article analyzes the clinical manifestations of the most common viral infectious diseases in children, accompanied by spotty exanthema, provides brief data on the etiology, pathogenesis and epidemiology of these infections, shows photographs for each of the described nosological forms from the authors' personal archives.

Effect of Chronic Administration of Recombinant Bovine Tumor Necrosis Factor to Cattle

1989 ◽  
Vol 26 (6) ◽  
pp. 462-472 ◽  
Author(s):  
H. Bielefeldt Ohmann ◽  
M. Campos ◽  
M. Snider ◽  
N. Rapin ◽  
T. Beskorwayne ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Infectious Diseases ◽  
Tumor Necrosis ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Prolonged Treatment ◽  
Chronic Infections ◽  
Necrosis Factor Alpha ◽  
Fat Depots ◽  
Necrosis Factor

Cachectin/tumor necrosis factor-alpha (TNF), a protein produced by macrophages upon stimulation, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in chronic infectious diseases. In order to study further the potential role of TNF in infectious diseases, a homologous system was employed in which recombinant Escherichia coli (E. coli) derived bovine TNF (rBoTNF) was injected in cattle, either as a single bolus or in a repetitive treatment-regime. No clinical signs were observed, although changes occurred in hematologic and immunologic parameters when less than 0.5 mg of TNF/100 kg body weight was administered twice daily for 18 days. Prolonged treatment with 0.05–0.5 mg/100 kg induced histologic but no gross changes in the kidneys and liver. When doses were increased above 0.5 mg/100 kg, depression, anorexia, cachexia, and diarrhea appeared rapidly. Pathologic changes were apparent in various tissues including liver, kidneys, and lymphoid organs; body fat depots were depleted. Most of these changes appeared to be reversible; return to normal tissue-morphology occurred within 3 weeks of withdrawal of rBoTNF. The clinical and pathologic changes induced by prolonged rBoTNF administration resembled those observed in some chronic parasitic and viral infections of cattle in which macrophage-activation characteristically occur. Our finding may be relevant to the elucidation of the pathogenesis of these and other chronic infections.

scholarly journals PECULIARITIES OF CLINICAL MANIFESTATIONS OF CNS INFECTIONS IN CHILDREN

2018 ◽  
Vol 3 (4) ◽  
pp. 31-37
Author(s):  
T. S. Berezovskaya ◽  
N. A. Miromanova ◽  
A. M. Miromanov
Keyword(s):  
Central Nervous System ◽  
Septic Shock ◽  
Nervous System ◽  
Infectious Diseases ◽  
Cerebral Edema ◽  
Bacterial Infections ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Adverse Outcomes ◽  
Neck Stiffness

At present, the neuroinfections in children are a socially significant problem, as they can lead to disability and death.Aim. To reveal the patterns of clinical manifestations of neuroinfections in the children’s central nervous system.Materials and methods. We investigated 91 cases of neuroinfections in children. The children underwent treatment in the  Regional Infectious Diseases Hospital (Chita) between 2007 and  2014. Among 91 cases, 32 patients had viral neuroinfections and 59 had bacterial infections.Results. The young boys have bacterial neuroinfections more often. Headaches were found in 73.6 % of children; more often in children  with viral neuroinfections – in 87.5 %, and less frequent in children  with bacterial neuroinfections – in 66.1 %, p ˂ 0.01 The disease  often starts with fever and vomiting. The neck stiffness and the  Kernig symptom were often found in patients with bacterial  neuroinfections persisting for 5 ± 1.7 days and 4 ± 1.9 days  correspondingly, in children with viral neuroinfections – for 3 ± 1.4  and 3 ± 1.2 days, p ˂ 0.05. Pneumococcal etiology of the disease  underlies the most severe and protracted cases in the course of  neuroinfections. Pneumococcus causes the most severe and  protracted diseases of the nervous system. Most often the bacterial  neuroinfections cause cerebral edema and septic shock.Conclusions. Neuroinfections have typical clinical signs that need to be properly interpreted and evaluated by physicians to reduce adverse outcomes.

Ophthalmic Manifestations of Neurologic, Rheumatologic, and Infectious Diseases in the Context of the novel Coronavirus Disease 2019 Pandemic: A Case Series

2021 ◽  
Keyword(s):  
Infectious Diseases ◽  
Clinical Manifestations ◽  
Case Series ◽  
Clinical Findings ◽  
The Novel ◽  
Altered Level ◽  
Multiple Systems ◽  
Ocular Manifestations ◽  
Ophthalmic Manifestations ◽  
Novel Coronavirus

The novel Coronavirus Disease 2019 (COVID-19) is known to present with a broad range of clinical manifestations. While symptoms such as fever, cough, dyspnea, myalgias, diarrhea, anosmia, and ageusia predominate, less common manifestations involving multiple systems have also been described. Some reported ocular manifestations include symptoms associated with keratoconjunctivitis, such as chemosis, ocular pain, photophobia, dry eye and tearing [1]. Neurological symptoms in addition to smell and taste dysfunction have been commonly described as well, and include headache, ataxia, dizziness, altered level of consciousness, and stroke [2]. Whether these neuro-ophthalmologic findings reflect direct involvement of these systems or a more generalized response to SARS-CoV-2 infection remains uncertain. Many other neurologic, rheumatologic, and infectious diseases also present with similar clinical findings as those described in COVID-19, further complicating the diagnostic picture. In this case series, we examine several patients presenting with unusual neuro-ophthalmological manifestations and discuss similarities of these findings with those seen in SARS-CoV-2 infection, and review current literature describing possible mechanisms underlying similar findings in patients with confirmed COVID-19.

Urinary tract infections in obstetrics and gynecology

2015 ◽  
Vol 64 (6) ◽  
pp. 91-104 ◽  
Author(s):  
Elena Vasilyevna Shipitsyna ◽  
Tatyana Alekseyevna Khusnutdinova ◽  
Alevtina Mikhailovna Savicheva ◽  
Tatyana Aykovna Ayvazyan
Keyword(s):  
Urinary Tract ◽  
Antimicrobial Resistance ◽  
Infectious Diseases ◽  
Urinary Tract Infections ◽  
Clinical Manifestations ◽  
Clinical Importance ◽  
Infectious Complications ◽  
Obstetrics And Gynecology ◽  
Tract Infections ◽  
In Pregnancy

Urinary tract infections (UTIs) are among the most common infectious diseases in women, and are the most frequent cause of infectious complications of pregnancy. This paper reviews current scientific and methodical literature on UTIs in obstetrics and gynecology. Aspects of clinical importance of UTIs (epidemiology, clinical manifestations, complications), their etiology, antimicrobial resistance of UTIs agents were discussed, and current recommendations on diagnostics and treatment of UTIs were summarized. Special attention was paid to UTIs in pregnancy.

Current parasitic and infectious diseases of horses

2020 ◽  
Author(s):  
Vladislav Belimenko ◽  
Pavel Hristianovskiy ◽  
Aleksey Gulyukin ◽  
Svetlana Alekseenkova ◽  
Aleksey Laishevcev
Keyword(s):  
Veterinary Medicine ◽  
Infectious Diseases ◽  
Clinical Manifestations ◽  
Biological Features ◽  
Treatment And Prevention ◽  
Wide Range ◽  
Modern Methods

The main infectious diseases of ungulates caused by helminths, ticks, insects, protozoa, bacteria and viruses are considered. The questions of etiology, biological features and resistance of pathogens, distribution and clinical manifestations of diseases are highlighted. Attention is paid to modern methods of diagnosis, treatment and prevention of infectious diseases of horses. Part 1 is written by Professor P. I. Khristianovsky, V. V. Belimenko, A. M. Gulyukin, A. I. Laishevtsev and E. V. Novosad; part 2 is written by Professor K. P. Yurov and S. V. Alekseenkova. It is intended for students studying in the specialty "veterinary medicine", practical veterinarians and a wide range of horse lovers.

scholarly journals The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: Clinical Practice Guidelines by the Infectious Diseases Society of America

2006 ◽  
Vol 43 (9) ◽  
pp. 1089-1134 ◽  
Author(s):  
Gary P. Wormser ◽  
Raymond J. Dattwyler ◽  
Eugene D. Shapiro ◽  
John J. Halperin ◽  
Allen C. Steere ◽  
...  
Keyword(s):  
Lyme Disease ◽  
Infectious Diseases ◽  
Health Care Providers ◽  
Treatment Guidelines ◽  
Clinical Manifestations ◽  
Previous Treatment ◽  
Care Providers ◽  
Human Granulocytic Anaplasmosis ◽  
Treatment And Prevention ◽  
Granulocytic Anaplasmosis

Abstract Evidence-based guidelines for the management of patients with Lyme disease, human granulocytic anaplasmosis (formerly known as human granulocytic ehrlichiosis), and babesiosis were prepared by an expert panel of the Infectious Diseases Society of America. These updated guidelines replace the previous treatment guidelines published in 2000 (Clin Infect Dis 2000; 31[Suppl 1]:1–14). The guidelines are intended for use by health care providers who care for patients who either have these infections or may be at risk for them. For each of these Ixodes tickborne infections, information is provided about prevention, epidemiology, clinical manifestations, diagnosis, and treatment. Tables list the doses and durations of antimicrobial therapy recommended for treatment and prevention of Lyme disease and provide a partial list of therapies to be avoided. A definition of post–Lyme disease syndrome is proposed.

scholarly journals Acute Schistosomiasis in Brazilian Traveler: The Importance of Tourism in The Epidemiology of Neglected Parasitic Diseases

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Diego Averaldo Guiguet Leal ◽  
Regina Maura Bueno Franco ◽  
Maria Francisca Neves ◽  
Luciana Franceschi Simões ◽  
Letícia Aparecida Duart Bastos ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Infectious Diseases ◽  
Primary Infection ◽  
Travel Medicine ◽  
Clinical Manifestations ◽  
Clinical History ◽  
Parasitic Diseases ◽  
Temporal Delay ◽  
Travel History ◽  
Detailed Clinical History

Parasitic infectious diseases acquired in tourist areas may pose a challenge to physicians and to travel medicine practitioners. Acute schistosomiasis may be seen in returning travelers and migrants after primary infection. This form of schistosomiasis is frequently misdiagnosed due to its temporal delay and its nonspecific presentation and might occur even in countries where the disease is endemic, such as in Brazil. The patient developed the acute phase of schistosomiasis with severe clinical manifestations. The quantitative analysis revealed the presence of 240 eggs per gram of stool. The treatment was administered with oxamniquine, and the control of cure of the patient was monitored and was favorable. The present paper aims to emphasize the importance of a detailed clinical history including information regarding travel history.

scholarly journals Overlapping clinical manifestations of COVID-19 with endemic infectious diseases in Pakistan: A looming threat of multiple lethal combinations

2021 ◽  
Vol 11 (1) ◽  
pp. 1873494
Author(s):  
Muhammad Suleman Rana ◽  
Muhammad Usman ◽  
Muhammad Masroor Alam ◽  
Aamer Ikram ◽  
Muhammad Salman
Keyword(s):  
Infectious Diseases ◽  
Clinical Manifestations

scholarly journals CLINICAL EFFICIENCY OF LEEVOFLOXACIN IN COMPLEX TREATMENT OF PATIENTS WITH NON-HOSPITAL PNEUMONIA

2018 ◽  
Keyword(s):  
Infectious Diseases ◽  
Respiratory Tract ◽  
Soft Tissues ◽  
Plasma Concentrations ◽  
Clinical Manifestations ◽  
Antibacterial Drug ◽  
Chronic Lung Diseases ◽  
The Creation ◽  
High Concentrations ◽  
Tract Infections

The results of the study, during which the effectiveness of levofloxacin in the treatment of patients with non-hospital pneumonia was assessed in the article. Levofloxacin, according to clinical studies, is indicated to patients for the treatment of respiratory tract infections (acute bronchitis, pneumonia, lung abscess, exacerbation of chronic lung diseases, etc.), infections of the kidneys and urinary system, uncomplicated infections of the skin and soft tissues, infections of bone tissue and joints, infectious diseases of the gastrointestinal tract, etc. The advantage of levofloxacin and other new fluoroquinolones is their improved activity against S. pneumoniae and high efficacy against most causative agents of infectious diseases of the lower respiratory tract. The action of this drug is associated with a wide distribution in the tissues and the creation of high concentrations in biological media that exceed plasma concentrations. Levofloxacin is characterized by minimal metabolism, good penetration and the creation of high concentrations in lung tissue, sputum, bronchial secretions, alveolar macrophages, which is very important in the treatment of patients with respiratory infections. All this was the basis for the use of levofloxacin as an etiotropic drug for the treatment of patients with non-hospital pneumonia (NP). In the work it was shown that levofloxacin (Abifloks) is a highly effective antibacterial drug for the treatment of NP with varying degrees of severity. Positive dynamics of the clinical manifestations of the disease was noted already on the 3rd day after the start of therapy. In addition, Abifloks has good therapeutic tolerance in patients with non-hospital pneumonia. The identified side effects were short-lived and did not require additional drug correction and discontinuation of the drug. The optimally chosen dosing regimen (500 mg intravenously once) allows maximum adherence to the intake regimen and maintaining the necessary concentration in the inflammatory focus, which affects the clinical and bacteriological effectiveness of the therapy.

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