scholarly journals Relevance of the body mass index in the cognitive status of diabetic patients with different alcohol-drinking patterns

2014 ◽  
Vol 66 (1) ◽  
pp. 347-353
Author(s):  
Serban Lacramioara ◽  
Cristina Toarba ◽  
Simona Hogas ◽  
A. Covic ◽  
A. Ciobica ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Alcohol Consumption ◽  
Alcohol Drinking ◽  
The Body ◽  
Control Group ◽  
Diabetic Patients ◽  
Inverse Association ◽  
Drinking Patterns ◽  
Alcohol Drinking Patterns ◽  
The Relationship

Nowadays the general relevance of alcohol consumption in diabetes is extremely controversial. There are recent reports that alcohol consumption could result in a decreased incidence of diabetes, as well as other studies demonstrating a positive association between alcohol consumption and type 2 diabetes; there are also reports arguing for an inverse association between the two or for no correlation at all. The different results obtained in these studies could be explained by the existence of several confounders that could influence the outcome of the aforementioned studies. In this paper, we studied the possible relevance of BMI as a confounder in the relationship between alcohol consumption in diabetes and cognitive function, by analyzing the correlations between BMI values in diabetic patients with different alcohol drinking patterns and the subdomains from some main psychometric tests, such as MMSE (Mini-Mental State Examination) and MOCA (Montreal Cognitive Assessment). Our results provide evidence for BMI as a possible confounder of the relationship between alcohol consumption in diabetes and cognitive function. We found a significant increase (p<0.0001) in BMI values in patients with diabetes compared to our control group. Most importantly, significant correlations between BMI parameters in alcohol-consuming diabetic patients and most of the subdomains for psychometric testing.

scholarly journals Genome-wide association study of alcohol consumption in Russian population

2018 ◽  
Author(s):  
Igor Nizamutdinov ◽  
Yaroslav Popov ◽  
Dmitriy Romanov ◽  
Ekaterina Surkova ◽  
Valery Ilinsky ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Association Study ◽  
Alcohol Drinking ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Drinking Patterns ◽  
Genome Wide ◽  
A Genome ◽  
Alcohol Drinking Patterns ◽  
Nervous System Function

Liability to alcohol dependence is heritable, but little is known about its complex polygenic architecture. We performed a genome-wide association study (GWAS) of self-reported alcohol consumption in 1798 of Russian individuals. No SNP reached genome-wide significance for any alcohol drinking patterns: never drinking, everyday drinking, once per week drinking and once per month drinking. Polymorphisms in previously reported genes of KLB and AUTS2 were significant associated with everyday drinking and once per week drinking patterns, respectively. We also found associations of genes involved in nervous system function and mental disorders with some alcohol drinking patterns. This study identifies novel gene associations that should be the focus of future studies investigating the neurobiology of alcohol consumption.

scholarly journals Black–White Differences in the Relationship Between Alcohol Drinking Patterns and Mortality Among US Men and Women

2015 ◽  
Vol 105 (S3) ◽  
pp. S534-S543 ◽  
Author(s):  
Chandra L. Jackson ◽  
Frank B. Hu ◽  
Ichiro Kawachi ◽  
David R. Williams ◽  
Kenneth J. Mukamal ◽  
...  
Keyword(s):  
Alcohol Drinking ◽  
Drinking Patterns ◽  
Men And Women ◽  
Alcohol Drinking Patterns ◽  
The Relationship

scholarly journals Serum Iron and Risk of Diabetic Retinopathy

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2297
Author(s):  
Ying-Jen Chen ◽  
Jiann-Torng Chen ◽  
Ming-Cheng Tai ◽  
Chang-Min Liang ◽  
Yuan-Yuei Chen ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Iron Metabolism ◽  
Serum Iron ◽  
Cutoff Point ◽  
Fundus Photography ◽  
Control Group ◽  
Diabetic Patients ◽  
Inverse Association ◽  
Operating Characteristics ◽  
The Relationship

Background: Diabetic retinopathy (DR) is indicated as a major cause of blindness in the world. Emerging evidence supports the interaction of iron metabolism with diabetes. However, little research is available concerning the relationship between iron metabolism and DR. The intent of this paper is to describe the correlation between serum iron and the occurrence of DR. Methods: A total of 5321 participants who underwent related examinations as part of the National Health and Nutrition Examination Survey (2005–2008) were included. DR was defined by the criteria of the Early Treatment for Diabetic Retinopathy Study based on nonmydriatic fundus photography. The cutoff point of serum iron for DR was explored by the receiver operating characteristics curve. The relationship of serum iron with the occurrence of DR was explored by multivariate logistic regression models. Results: Participants with DR had significantly lower serum iron than the control group. Serum iron was negatively correlated with the occurrence of DR after the adjustment of pertinent variables (an odds ratio (OR) of 0.995 (95% CI: 0.992–0.999)). After dividing serum iron into quartiles, the third quartile was associated with DR with an OR of 0.601 (95% CI: 0.418–0.863). Furthermore, the cutoff point of serum iron had an inverse relationship for the occurrence of DR with an OR of 0.766 (95% CI: 0.597–0.984). Conclusion: Serum iron has an inverse association with the occurrence of DR in diabetic adults. The assessment of serum iron levels might be a part of follow-up visits with diabetic patients.

scholarly journals Association of Alcohol Drinking Patterns with Metabolic Syndrome and Its Components in Korean Adults: The Korea National Health and Nutrition Examination Survey 2016–2018

2021 ◽  
Vol 18 (12) ◽  
pp. 6433
Author(s):  
Seung Won Lee ◽  
Sung-In Jang
Keyword(s):  
Metabolic Syndrome ◽  
Binge Drinking ◽  
Alcohol Drinking ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Drinking Patterns ◽  
Cross Sectional ◽  
Korean Adults ◽  
Alcohol Drinking Patterns ◽  
Drinking Frequency

This study examined the association of alcohol drinking patterns with metabolic syndrome (MetS) and its components in a nationally representative sample of South Korean adults. The cross-sectional study included 12,830 current drinkers (6438 men and 6392 women) who were at least 20 years old. Measures of alcohol drinking patterns included average drinking frequency, usual quantity, and binge drinking frequency over the past year. Multivariate logistic regression was performed to estimate odds ratios and 95% confidence intervals for MetS and its components according to alcohol drinking patterns, and also to examine linear trends in these relationships. The prevalence of MetS was 1822 (26.2%) in men and 1313 (17.5%) in women. After adjusting for potential confounding factors, drinking quantity and binge drinking frequency were positively associated with MetS in both sexes. Regarding components of MetS, while the risk of low HDL cholesterol decreased as drinking frequency increased, other MetS components (abdominal obesity, high blood pressure, and impaired fasting glucose) worsened. Our results suggest that separate management of each component of MetS will be required to protect cardio-metabolic health, and a healthy drinking culture that refrains from binge drinking should be established in the context of public health.

scholarly journals Alcohol Consumption at Any Level Increases Risk of Injury Caused by Others: Data from the Study on Global AGEing and Adult Health

2015 ◽  
Vol 9s2 ◽  
pp. SART.S23549 ◽  
Author(s):  
Thomas Clausen ◽  
Priscilla Martinez ◽  
Andy Towers ◽  
Thomas Greenfield ◽  
Paul Kowal
Keyword(s):  
High Risk ◽  
Alcohol Use ◽  
Older Adult ◽  
Emerging Economies ◽  
Alcohol Drinking ◽  
Adult Health ◽  
Drinking Patterns ◽  
Risk Of Injury ◽  
Alcohol Drinking Patterns ◽  
Global Ageing

Background Alcohol use is a well-known risk factor for injury. However, information is needed about alcohol drinking patterns and the risk of injury among older adults in low- and middle-income countries as this population grows. We aimed to examine the influence of drinking patterns on the burden of injury and investigate factors associated with different types of injury in older populations in six emerging economies. Methods Data from more than 37,0 adults aged 50 years and older were included from the Study on Global AGEing and Adult Health (SAGE) Wave 1 conducted in six emerging economies, namely, China, Ghana, India, Mexico, Russia, and South Africa. We investigated past-year reported injuries from falls, traffic accidents, and being hit or stabbed. Alcohol drinking patterns were measured as lifetime abstinence, ever but not past- week use, and gender-specific past-week low-risk and high-risk use. We stratified by gender and used logistic regression models to observe the association between alcohol drinking pattern and risk of injury by controlling for other factors. Results During the year prior to interview, 627 (2.2%) subjects reported bodily injury resulting from a car accident, 1,156 (4.2%) from a fall, and 339 (.9%) from being hit or stabbed during the past year. For women, only being a high-risk drinker increased the risk of being hit or stabbed, whereas for men, all levels of drinking were associated with an increased risk of being hit or stabbed. We observed a higher risk of being hit or stabbed from past-week high-risk drinking among women (odds ratio [OR] = 6.09, P < 0.01) than among men (OR = 3.57, P < 0.01). We observed no association between alcohol drinking pattern and injury due to car accidents for either women or men. Conclusions The risk of experiencing injury due to violence increased with level of alcohol exposure of the victim. The increase in alcohol use in emerging economies calls for further study into the consequences of alcohol use and for public health initiatives to reduce the risk of violence in older adult populations, with special attention to the experience of older adult women.

scholarly journals Exercise and dietary program-induced weight reduction is associated with cognitive function among obese adolescents: a longitudinal study

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3286 ◽  
Author(s):  
Chun Xie ◽  
Xiaochun Wang ◽  
Chenglin Zhou ◽  
Chang Xu ◽  
Yu-Kai Chang
Keyword(s):  
Executive Function ◽  
Cognitive Function ◽  
Weight Status ◽  
Flanker Task ◽  
Control Group ◽  
Obese Adolescents ◽  
School Activities ◽  
Combined Exercise ◽  
Quasi Experimental ◽  
The Relationship

Objective The present study was to determine the effect of a combined exercise and dietary program on cognitive function as well as the relationship between the program-induced weight change and cognitive function alterations. Design The study applies a quasi-experimental design. Methods Fifty-eight adolescents with obese status (body mass index, BMI >28 kg/m2) were assigned to either an experiment (n = 30) or control group (n = 28). Participants in the experiment group received a scheduled program with a specific exercise protocol (two sessions per day, six days per week) and diet plan for four consecutive weeks; the control group was instructed to maintain their normal school activities. The primary outcome measures were anthropometric data and flanker task performance. Results The combined program led to reduced BMI with maintenance of the incongruent accuracy in the experiment group, but the incongruent accuracy decreased in the control group after the four-week period. Additionally, the change in weight status between post- and pre-test measurements was inversely correlated with the change in incongruent accuracy. Conclusion The combined exercise and dietary program resulted in decreased weight and enhanced executive function in the obese adolescents, and the weight alteration may be considered the mediator between the intervention and executive function.

scholarly journals Echocardiographic evaluation of ventricular septal defect haemodynamics

2007 ◽  
Vol 135 (9-10) ◽  
pp. 541-546
Author(s):  
Vesna Miranovic
Keyword(s):  
Ventricular Septal Defect ◽  
Pulmonary Artery ◽  
Body Surface ◽  
Septal Defect ◽  
Left Ventricular ◽  
The Body ◽  
Control Group ◽  
Healthy Children ◽  
And Control ◽  
The Relationship

Introduction Ventricular septal defect (VSD) is an opening in the interventricular septum. 30-50% of patients with congenital heart disease have VSD. Objective The aim of the study was to determine the dependence of the left ventricular diastolic dimension (LVD), left ventricular systolic dimension (LVS), shortening fraction (SF), left atrium (LA), pulmonary artery truncus (TPA) on the body surface and compare their values among experimental, control and a group of healthy children. Values of maximal systolic gradient pressure (Pvsd) of VSD were compared with children from one experimental and control group. Method Children were divided into three groups: experimental (32 children with VSD that were to go to surgery), control (20 children with VSD who did not require surgery) and 40 healthy children. Measurements of LVD, LVS, SF, LA, TPA were performed in accordance to recommendations of the American Echocardiographic Association. The value of Pvsd was calculated from the maximal flow velocity (V) in VSD using the following formula: Pvsd=4xV? (mm Hg). Results For children from the experimental group, the relationship between the body surface and the variability of the LVD was explained with 56.85%, LVS with 66.15%, SF with 4.9%, TPA with 58.92%. For children from the control group, the relationship between the body surface and the variability of LVD was explained with 88.8%, LVS with 72.5%, SF with 0.42%, PA with 58.92%. For healthy children, the relationship between the body surface and the variabilitiy of the LVD was explained with 88.8%, LVS with 88.78%, SF with 5.25% and PA with 84.75%. There was a significant statistical difference between average values of Pvsd in the experimental and control group (p<0.02). Conclusion The presence of the large VSD has an influence on the enlargement of LVD, LVS, SF, TPA. The enlargement of the size of the pulmonary artery depends on the presence of VSD and there is a direct variation in the magnitude of the shunt. There is a relationship and significant dependence of the LVS and LVD on the body surface. There is no statistically significant dependence between SF and body surface.

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