Bioactive compounds and antioxidant properties of dried apricot

Dried apricot was extracted using two different solvents: 80% ethanol and hexane. The contents of total phenolics, flavonoids and anthocyanins were determined in ethanol apricot extract (EAE), while the carotenoid content was determined in hexane apricot extracts (HAE) by spectrophotometric method. The detected amounts of bioactive compounds in dried apricot were: phenolics 498.13 ? 12.04 mg GAE/100g DA, flavonoids 218.45 ? 14.14 mg R/100g DA and anthocyanins 3.08 ? 0.40 mg CGE/100g DA. In dried apricot the ?-carotene was present in the amount of 0.56 ? 0.03 mg/100g DA. Some individual phenolic compounds in EAE were determined by HPLC analysis and the most dominant compound was gallic acid (35.02 ? 1.65 mg/100g DA). Free radical scavenging activities of EAE and HAE were tested spectrophotometrically using stable DPPH radicals and reducing power method. The EC50 value for EAE was 2.05 ? 0.06 mg/ml and for HAE was 6.28 ? 0.01 mg/ml. The RP0.5 values determined by reducing power method were 6.11 ? 0.01 mg/ml for EAE and 62.04 ? 0.03 mg/ml for HAE. The results indicate that dried apricot can be a valuable source of natural antioxidants and can be used as a functional food ingredient in the food industry.

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Composition, color and antioxidant properties of cocoa shell at different roasting temperatures

Food Research ◽

10.26656/fr.2017.4(3).251 ◽

2019 ◽

Vol 4 (3) ◽

pp. 585-593

Author(s):

R. Fakhlaei ◽

Rozzamri A. ◽

N. Hussain

Keyword(s):

Antioxidant Activity ◽

Radical Scavenging Activity ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Ethanolic Extract ◽

Natural Antioxidants ◽

Food Ingredient ◽

Cocoa Products ◽

Cocoa Shell ◽

L Value

Cocoa shell is underexploited and is considered as waste. However, roasting cocoa is a fundamental step in producing cocoa products. Composition of the cocoa shell depends on the origin whereas cocoa processing involves fermentation, drying and roasting. However, scarce research has been conducted to analyze the composition of Malaysian cocoa shells at different roasting temperatures. Therefore, this research aims to determine the effect of different roasting temperatures (110, 120, 130, 140 and 150°C) on the proximate composition, colour and antioxidant activity of cocoa shell. Changes in antioxidant activity and polyphenol content were recorded. Fiber and moisture content were significantly (p<0.05) higher in unroasted cocoa shell. However, the protein was found to decrease significantly (p<0.05) after roasting at 150°C (10.93%). Fat content was found higher in roasted cocoa shell at 150°C (6.82%) compared to the unroasted cocoa shell (6.09%). The colour (L value) recorded significantly (p<0.05). the highest for unroasted cocoa shell (51.28) and the lowest at 150°C (47.93), DPPH radical scavenging activity of ethanolic extract of cocoa shell was significantly (p<0.05) higher in 0% ethanol concentration compared to other ethanol concentrations (20, 50, 80 and 100%). The roasted cocoa shell may be considered as a source of natural antioxidants for functional food development and intermediate food ingredient.

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Antioxidant Potential of Chestnut (Castanea sativa L.) and Almond (Prunus dulcis L.) By-products

Food Science and Technology International ◽

10.1177/1082013209353983 ◽

2010 ◽

Vol 16 (3) ◽

pp. 209-216 ◽

Cited By ~ 25

Author(s):

J.C.M. Barreira ◽

I.C.F.R. Ferreira ◽

M.B.P.P. Oliveira ◽

J.A. Pereira

Keyword(s):

Lipid Peroxidation ◽

Bioactive Compounds ◽

Radical Scavenging Activity ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Reducing Power ◽

Castanea Sativa ◽

Thiobarbituric Acid ◽

Waste Products ◽

By Products

The antioxidant properties of almond green husks (Cvs. Duro Italiano, Ferraduel, Ferranhês, Ferrastar and Orelha de Mula), chestnut skins and chestnut leaves (Cvs. Aveleira, Boa Ventura, Judia and Longal) were evaluated through several chemical and biochemical assays in order to provide a novel strategy to stimulate the application of waste products as new suppliers of useful bioactive compounds, namely antioxidants. All the assayed by-products revealed good antioxidant properties, with very low EC50 values (lower than 380 μg/mL), particularly for lipid peroxidation inhibition (lower than 140 μg/mL). The total phenols and flavonoids contents were also determined. The correlation between these bioactive compounds and DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity, reducing power, inhibition of β-carotene bleaching and inhibition of lipid peroxidation in pig brain tissue through formation of thiobarbituric acid reactive substances, was also obtained. Although, all the assayed by-products proved to have a high potential of application in new antioxidants formulations, chestnut skins and leaves demonstrated better results.

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Mechanism of Action against Food Spoilage Yeasts and Bioactivity of Tasmannia lanceolata, Backhousia citriodora and Syzygium anisatum Plant Solvent Extracts

Foods ◽

10.3390/foods7110179 ◽

2018 ◽

Vol 7 (11) ◽

pp. 179 ◽

Cited By ~ 3

Author(s):

Fahad Alderees ◽

Ram Mereddy ◽

Dennis Webber ◽

Nilesh Nirmal ◽

Yasmina Sultanbawa

Keyword(s):

Escherichia Coli ◽

Bioactive Compounds ◽

Mechanism Of Action ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Reducing Power ◽

Antimicrobial Activities ◽

Weak Acid ◽

Diffusion Method ◽

Agar Disc

Bioactive properties of solvent extracts of Tasmannia lanceolata, Backhousia citriodora and Syzygium anisatum investigated. The antimicrobial activities evaluated using agar disc diffusion method against two bacteria (Escherichia coli and Staphylococcus aureus) and six weak-acid resistant yeasts (Candida albicans, Candida krusei, Dekkera anomala, Rhodotorula mucilaginosa, Saccharomyces cerevisiae and Schizosaccharomyces pombe). The antioxidant activities determined using DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging and reducing power assays. Quantification of major active compounds using ultra-high performance liquid chromatography. Extracts showed broad-spectrum antifungal activity against weak-acid resistant yeasts in comparison to the standard antifungal agents, fluconazole and amphotericin B. Dekkera anomala being the most sensitive and strongly inhibited by all extracts, while Escherichia coli the least sensitive. Polygodial, citral and anethole are the major bioactive compounds identified in Tasmannia lanceolata, Backhousia citriodora and Syzygium anisatum, respectively. Hexane extracts contain the highest amount of bioactive compounds and demonstrate the strongest antimicrobial activities. Methanol and ethanol extracts reveal the highest phenolic content and antioxidant properties. Fluorescence microscopic results indicate the mechanism of action of Backhousia citriodora against yeast is due to damage of the yeast cell membrane through penetration causing swelling and lysis leading to cell death.

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Phenolic production and antioxidant properties of some Macedonian medicinal plants

Open Life Sciences ◽

10.2478/s11535-014-0322-1 ◽

2014 ◽

Vol 9 (9) ◽

pp. 888-900 ◽

Cited By ~ 12

Author(s):

Oliver Tusevski ◽

Aneta Kostovska ◽

Ana Iloska ◽

Ljubica Trajkovska ◽

Sonja Simic

Keyword(s):

Phenolic Compounds ◽

Medicinal Plants ◽

Antioxidant Capacity ◽

Total Phenolics ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Reducing Power ◽

Natural Antioxidants ◽

Pharmaceutical Industries ◽

Promising Source

AbstractInvestigations have been made to study the production of phenolic compounds (total phenolics, flavonoids and phenylpropanoids) and total antioxidant capacity in 27 Macedonian traditional medicinal plants to improve its potential as a source of natural antioxidants. Antioxidant potential of plant extracts was analyzed by five different assays: cupric reducing antioxidant capacity (CUPRAC), phosphomolybdenum method (PM), reducing power (RP), 2,2-diphenyl-1-picrylhydrazyl (DPPH·) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS·+) radical scavenging activity. Origanum vulgare extract consistently exhibited the highest content of phenolic compounds and the strongest antioxidant capacity based on the tests performed, and can be proposed as a promising source of natural antioxidants. Melissa officinalis and Salvia ringens were also identified as valuable sources of antioxidant compounds. A positive linear correlation between antioxidant activity and total phenolics, flavonoids and phenylpropanoids indicates that these compounds are likely to be the main antioxidants contributing to the observed activities of evaluated plants. These findings suggest that the medicinal plants studied in this paper are good sources of bioactive compounds for the food and pharmaceutical industries.

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Evolution of antioxidant properties of orange beverage during storage: Effects of time and temperature

Acta Universitatis Cibiniensis Series E Food Technology ◽

10.2478/aucft-2021-0027 ◽

2021 ◽

Vol 25 (2) ◽

pp. 293-300

Author(s):

Ouahiba Soufi ◽

Mostapha Bachir-Bey ◽

Saida Kessi ◽

Djamila Gani ◽

Nourredine Touati

Keyword(s):

Bioactive Compounds ◽

Storage Temperature ◽

Antioxidant Activities ◽

Radical Scavenging Activity ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Reducing Power ◽

Duration Of Storage ◽

Antioxidant Parameters ◽

Storage Effects

Abstract Fruit beverages are the most consumed refreshing products worldwide. The quality of these drinks is not only influenced by the initial composition of the product but also by conditions and duration of storage. The purpose of the present investigation was to evaluate the incidence of two conservation parameters (temperature and time) on some bioactive compounds (phenolic, flavonoid, and carotenoid contents) and antioxidant capacity, measured by free radical scavenging activity (RSA) and ferric reducing power (FRP), on orange beverage during storage. The industrial drinking product freshly procured were subjected to storage under variable temperatures (5, 25, 35, and 45 °C) then analyses of bioactive compounds contents and antioxidant activity were performed periodically (0, 10, 20, and 30 days). The results showed that the initial orange beverage was endowed with interesting phenolic compound contents and considerable antioxidant potential. In the exception of 5 °C, which provided steady antioxidant parameters, all other temperatures induced decreases of analyzed phytochemicals and antioxidant activities proportionally with raising of storage temperature. The duration of storage for the temperatures 25, 35, and 45 °C also affected negatively antioxidant parameters in a proportional manner to time. The orange beverage was an interesting natural source of bioactive compounds but the duration of storage in relation to temperature must be chosen properly.

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Accelerated solvent extraction of bioactive compounds from carrot: Optimization of response surface methodology

Journal of the Serbian Chemical Society ◽

10.2298/jsc180531068s ◽

2018 ◽

Vol 83 (11) ◽

pp. 1223-1228 ◽

Cited By ~ 1

Author(s):

Vanja Seregelj ◽

Vesna Tumbas-Saponjac ◽

Anamarija Mandic ◽

Gordana Cetkovic ◽

Jasna Canadanovic-Brunet ◽

...

Keyword(s):

Response Surface Methodology ◽

Solvent Extraction ◽

Response Surface ◽

Bioactive Compounds ◽

Radical Scavenging ◽

Reducing Power ◽

Accelerated Solvent Extraction ◽

Carotenoid Content ◽

Extraction Temperature ◽

Significant Difference

Carrot is considered to be rich in bioactive antioxidants, both lipophilic (carotenoids) and hydrophilic (phenolic compounds). In the present study, the conditions for accelerated solvent extraction (ASE) of bioactive compounds from carrots (Daucus carota L.) were optimized using response surface methodology (RSM). Box?Behnken design was employed for the experimental design to obtain the optimized combination of extraction temperature, time, and number of extraction cycles. Total carotenoid content (TCar), total polyphenol content (TPh), free radical scavenging activity (SA) and reducing power (RP) of the obtained extracts were used as responses for the optimization. Considering the four quality indicators, the ideal extraction conditions were found to be: 120 ?C, 60 min and three extraction cycles. Under these conditions, predicted values of 28.84 mg ?-carotene/100 g for TCar; 530.81 mg GAE/100 g for TPh; 2572.29 ?mol TE/100 g for SA and 1336.26 ?mol TE/100 g for RP were obtained with high desirability (0.975) and no significant difference (p < 0.05) with the experimental values.

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Punica granatum as a Source of Natural Antioxidant and Antimicrobial Agent; a Comprehensive Review on Related Investigations

Current Drug Discovery Technologies ◽

10.2174/1570163817666200430001822 ◽

2020 ◽

Vol 17 ◽

Author(s):

Atefeh Jalali ◽

Mohammadreza Kiafar ◽

Masih Seddigh ◽

Mohammad M. Zarshenas

Keyword(s):

Antioxidant Activities ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Natural Antioxidants ◽

Punica Granatum ◽

Antimicrobial Activities ◽

Natural Antioxidant ◽

Antiviral Activities ◽

Natural Foods

Background: The consumption of natural antioxidants is increasing due to the demand and tendency to natural foods. Punica granatum L. [Punicaceae] is a fruit with various bioactive ingredients. The effectiveness of this plant has been proved against various disorders such as hyperglycemia, hyperlipidemia, blood coagulation, infections, cancer, and dentistry. Among them, there are numerous researches on antimicrobial and antioxidant properties. Subsequently, the present study aimed to compile a review of those properties to outline this herb as a possible natural antioxidant and preservative. Methods: Synchronically, keywords "Punica granatum" with antimicrobial, or antibacterial, antifungal, antiviral, antioxidant and radical scavenging were searched through "Scopus" database up to 31st September 2019. Papers focusing on agriculture, genetics, chemistry, and environmental sciences were excluded and also related papers were collected. Results: Among 201 papers focusing on related activities, 111 papers have dealt with antioxidant activities focusing based on DPPH assay, 59 with antibacterial, on both gram+ and gram- bacteria, 24 with antifungal effects, mostly on Aspergillus niger and Candida albicans, and 7 papers with antiviral activities. There were about 50 papers focusing on in-vivo antioxidant activities of this plant. Conclusion: Taken together, botanical parts of P. granatum have possessed notable radical scavenging and antimicrobial activities that with these properties, this plant can be introduced as a natural safe source of preservative and antioxidant. Accordingly, P. granatum can be applied as excipient with the aforementioned properties in the pharmaceutical and food industries.

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Flavones and Their Analogues as Bioactive Compounds – An Overview

Mini-Reviews in Organic Chemistry ◽

10.2174/1570193x15666180418154510 ◽

2019 ◽

Vol 16 (4) ◽

pp. 377-391 ◽

Cited By ~ 1

Author(s):

B.S. Jayashree ◽

H. Venkatachalam ◽

Sanchari Basu Mallik

Keyword(s):

Biological Activity ◽

Free Radical ◽

Bioactive Compounds ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Cost Effective ◽

Free Radical Scavenging ◽

Polyphenolic Compounds ◽

Pharmacological Activities ◽

Poor Solubility

Flavonoids constitute a large group of polyphenolic compounds that are known to have antioxidant properties, through their free radical scavenging abilities. They possess a chromone (γ- benzopyrone) moiety, responsible for eliciting many pharmacological activities. Even though, natural flavonoids are highly potent, owing to their poor solubility, they are less used. Therefore, attempts have been made to improve their stability, solubility, efficacy and kinetics by introducing various substituents on the flavone ring. For nearly the last two decades, flavones were synthesized in our laboratory by simple, convenient and cost-effective methods, with the knowledge of both synthetic and semi-synthetic chemistry. In this direction, it was considered worthwhile to present an overview on the synthesized flavonoids. This review creates a platform for highlighting various modifications done on the flavone system along with their biological activity.

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Hepatoprotective studies on methanolic extract fractions of Lindernia ciliata and development of qualitative analytical profile for the bioactive extract

Clinical Phytoscience ◽

10.1186/s40816-019-0123-1 ◽

2019 ◽

Vol 5 (1) ◽

Author(s):

Praneetha Pallerla ◽

Narsimha Reddy Yellu ◽

Ravi Kumar Bobbala

Keyword(s):

Methanolic Extract ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Liver Homogenate ◽

Reducing Power ◽

Hepatoprotective Activity ◽

Total Phenolic ◽

Effective Fraction

Abstract Background The objective of the study is to evaluate the hepatoprotective activity of methanolic extract fractions of Lindernia ciliata (LC) and development of qualitative analytical profile of the bioactive fraction using HPLC fingerprinting analysis. All the fractions of methanolic extract of Lindernia ciliata (LCME) are assessed for their total phenolic, flavonoid contents and in vitro antioxidant properties by using DPPH, superoxide, nitric oxide, hydroxyl radical scavenging activities and reducing power assay. Acute toxicity study was conducted for all the fractions and the two test doses 50 and 100 mg/kg were selected for the hepatoprotective study. Liver damage was induced in different groups of rats by administering 3 g/kg.b.w.p.o. paracetamol and the effect of fractions were tested for hepatoprotective potential by evaluating serum biochemical parameters and histology of liver of rats. The effective fraction was evaluated for its antihepatotoxic activity against D-Galactosamine (400 mg/kg b.w. i.p.) and in vivo antioxidant parameters viz., Glutathione (GSH), Melondialdehyde (MDA) and Catalase (CAT) levels are estimated using liver homogenate. Results Among all the fractions, butanone fraction of LCME, (BNF-LCME) has shown better hepatoprotective activity and hence it is selected to evaluate the antihepatotoxicity against D-GaIN. The activity of BNF-LCME is well supported in in vitro and in vivo antioxidant studies and may be attributed to flavonoidal, phenolic compounds present in the fraction. Hence, BNF-LCME was subjected to the development of qualitative analytical profile using HPLC finger printing analysis. Conclusions All the fractions of LCME exhibited significant hepatoprotective activity and BNF-LCME (50 mg/kg) was identified as the most effective fraction.

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New insights of phenolic compounds from optimized fruit extract of Ficus auriculata

Scientific Reports ◽

10.1038/s41598-021-91913-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

M. Shahinuzzaman ◽

Parul Akhtar ◽

N. Amin ◽

Yunus Ahmed ◽

Farah Hannan Anuar ◽

...

Keyword(s):

Antioxidant Activity ◽

Bioactive Compounds ◽

Total Phenolic Content ◽

Phenolic Content ◽

Radical Scavenging Activity ◽

Radical Scavenging ◽

Reducing Power ◽

Total Phenolic ◽

Fruit Extract ◽

Optimum Extraction

AbstractIn this study, the extraction conditions extracted maximize amounts of phenolic and bioactive compounds from the fruit extract of Ficus auriculata by using optimized response surface methodology. The antioxidant capacity was evaluated through the assay of radical scavenging ability on DPPH and ABTS as well as reducing power assays on total phenolic content (TPC). For the extraction purpose, the ultrasonic assisted extraction technique was employed. A second-order polynomial model satisfactorily fitted to the experimental findings concerning antioxidant activity (R2 = 0.968, P < 0.0001) and total phenolic content (R2 = 0.961, P < 0.0001), indicating a significant correlation between the experimental and expected value. The highest DPPH radical scavenging activity was achieved 85.20 ± 0.96% at the optimum extraction parameters of 52.5% ethanol (v/v), 40.0 °C temperature, and 22 min extraction time. Alternatively, the highest yield of total phenolic content was found 31.65 ± 0.94 mg GAE/g DF at the optimum extraction conditions. From the LC–ESI–MS profiling of the optimized extract, 18 bioactive compounds were tentatively identified, which may regulate the antioxidant activity of fruits of F. auriculata.

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