Data linkage for public health research – the Fforestfach tyre fire

Background The Fforestfach tyre fire started on the 16th of June 2011 and continued to burn for 22 days. Smoke from tyre fires contain a number of chemicals that might cause health problems, especially for people who already have long-term health conditions. This research investigated whether people living close to the Fforestfach fire contacted their General Practice (GP) more often during the fire than they might have done otherwise. This is important both for the people living in the Fforestfach area and also for those living near similar fires in the future. Aim To use advances in mapping and data linkage techniques to assess associations between the Fforestfach fire incident and respiratory and cardiovascular health outcomes. The report focusses on the occurrence of respiratory and cardiovascular Read codes in patient’s GP records. Methods Using data linkage, information provided by the Met office was used to identify households likely to have been exposed to above threshold levels of pollution. Residents from these households were linked to their GP records via the Secure Anonymised Information Linkage (SAIL) databank. Logistic regression models tested associations between above-threshold exposure to a specific type of pollution (PM10) and an increase in GP contact. Results Regression modelling demonstrated a small but significant increase in GP contact for respiratory conditions in patients with pre-existing asthma. The models did not demonstrate any affect in the general population. Conclusion The study demonstrated the value of linking health and environmental data using advanced data linkage techniques. Findings support current health advice used in environmental incidents such as this, that individuals with certain chronic conditions may be more likely to experience symptoms when exposed to 24-hour mean concentrations of PM10 exceeding 50µg/m3; but the risk of significant symptoms as a result of such exposure in the general population is likely to be minimal.

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Abstract 37: The Association of Cardiorespiratory Fitness and Ideal Cardiovascular Health in the Aerobics Center Longitudinal Study

Circulation ◽

10.1161/circ.135.suppl_1.37 ◽

2017 ◽

Vol 135 (suppl_1) ◽

Author(s):

Leanna M Ross ◽

Jacob L Barber ◽

Xuemei Sui ◽

Steven N Blair ◽

Mark A Sarzynski

Keyword(s):

Longitudinal Study ◽

Cardiorespiratory Fitness ◽

Cardiovascular Health ◽

Smoking Status ◽

Cross Sectional ◽

Ideal Cardiovascular Health ◽

Logistic Regression Models ◽

Using Data ◽

Middle Aged Adults ◽

Aerobics Center Longitudinal Study

Purpose: To examine the cross-sectional association between cardiorespiratory fitness (CRF) and ideal cardiovascular health (CVH) in middle-aged adults. Methods: The association between CRF and ideal CVH score was examined in 11,590 adults (8,865 men, 2,725 women) from the Aerobics Center Longitudinal Study. CRF was measured as duration in minutes from a maximal treadmill test. The AHA’s ideal CVH score was calculated on a 14 point scale using data on smoking status, BMI, physical activity (MET-min/wk), healthy diet, total cholesterol, blood pressure, and fasting plasma glucose recorded between 1987 and 1999. Participants were grouped into categories of inadequate (0-4), average (5-9), and optimum (10-14) based on their CVH score. Three CRF groups were created from age- and sex-specific quintiles based on the previously established cutpoints of treadmill time: low, moderate, and high CRF. We used general linear and logistic regression models adjusted for age, sex, and year of examination to evaluate the association of CRF with ideal CVH score. Results: The mean CVH score for men was 8.4 ± 2.2 and 9.7 ± 2.0 for women. Approximately 33% of men and 57% of women had optimum CVH, while only a small proportion of participants had inadequate CVH (5.1% M, 1.4% F). Treadmill time was moderately correlated (p<0.0001) with CVH score in both men (r=0.56) and women (r=0.50). CRF explained 16% and sex 18% of the variance in CVH score (both p<0.0001). Our adjusted model found that participants in the optimum CVH category had 20% and 43% higher CRF levels than those in the average and inadequate CVH groups (p<0.0001), respectively ( Figure 1 ). The adjusted odds (95% CI) of having optimum CVH were 14.0 (11.0-17.8) and 3.1 (2.4-4.0) times greater for high CRF and moderate CRF, respectively, compared to low CRF (p<0.0001). Discussion: Higher levels of cardiorespiratory fitness are associated with better cardiovascular health profiles in both men and women. Thus, improving fitness represents a strategy to improve cardiovascular and public health.

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Do interviewer attitudes to data linkage influence respondents’ consent to linkage? Analysis of Understanding Society

European Journal of Public Health ◽

10.1093/eurpub/ckaa142 ◽

2020 ◽

Author(s):

Lynsey Patterson ◽

Sharon M Cruise ◽

Chris R Cardwell ◽

Dermot O’Reilly

Keyword(s):

Logistic Regression ◽

Data Security ◽

Record Linkage ◽

Data Linkage ◽

Perceived Usefulness ◽

Logistic Regression Models ◽

The Us ◽

Linkage Information ◽

Multi Level ◽

Interviewer Training

Abstract Background Variable consent rates threaten the validity of linked datasets. One modifiable element is the interviewer–respondent relationship. We examine interviewer attitudes to consent to linkage and the effect on respondent consent. Methods Subjects were 27 380 respondents from the Wave 1 Understanding Society (US) survey in Great Britain and 449 interviewers who completed the US Interviewer Survey. Two types of consent were considered: (i) whether the interviewer would hypothetically agree to having their data linked if he/she was an US respondent and (ii) whether the respondent consented to have their data linked. Factors influencing the interviewer’s propensity to link data were examined using logistic regression. The association between interviewer consent and respondent consent to health record linkage was assessed using multi-level logistic regression models. Results The interviewer’s propensity to consent to data linkage was strongly positively associated with its perceived usefulness: those that found it somewhat useful were 57% less likely to consent [adjusted odds ratio (AOR) 0.43, 95% CI: 0.22–0.82] compared to those who thought it was very useful. Positive beliefs about data security and their ability to understand the data linkage information were also associated. Respondents were 17% less likely to consent when interviewed by an interviewer who would not consent to record linkage (AOR 0.83, 95% CI: 0.71–0.97). Conclusions The interviewer’s propensity to consent was influenced by their beliefs about data linkage, which in turn influenced respondent consent. We recommend using interviewer training to emphasize the usefulness of data linkage and the measures around data security.

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Occupational lifting and risk of hypertension, stratified by use of anti-hypertensives, physical activity and age - a prospective cohort study

10.21203/rs.3.rs-61037/v1 ◽

2020 ◽

Author(s):

Mette Korshøj ◽

Harald Hannerz ◽

Ruth Frikke-Schmidt ◽

Jacob Louis Marott ◽

Peter Schnohr ◽

...

Keyword(s):

Physical Activity ◽

General Population ◽

Population Study ◽

Cardiovascular Health ◽

Leisure Time Physical Activity ◽

Cross Sectional ◽

General Population Study ◽

Logistic Regression Models ◽

Prospective Association

Abstract Background Prevalence of hypertension varies across occupations, maybe due to differences in exposure to occupational lifting. This study investigated associations between occupational lifting and hypertension, stratified by use of anti-hypertensives, leisure time physical activity (LTPA), occupational physical activity (OPA) and age.Methods Data from the Copenhagen General Population Study were included. The Copenhagen General Population Study was approved by the local ethical committee (H-KF-01-144/01), and all participation were conducted in accordance with the declaration of Helsinki. Multivariable logistic regression models, adjusted for sex, age, BMI, smoking, school education, mental stress and baseline blood pressure (BP), were applied to estimate: the (i) cross-sectional association (n=67,363) between occupational lifting and hypertension (using anti-hypertensives or BP ≥140/≥90 mmHg), (ii) prospective association (n=7,020) between occupational lifting and risk of an above median change in systolic BP (baseline to follow-up) and/or a shift from no use to use of anti-hypertensives, among the included population and stratified by use of anti-hypertensives, LTPA, OPA and age.Results Cross-sectionally, heavy occupational lifting lowered hypertension risk. Mean baseline BP, showed that the higher the level of LTPA the lower mean BP across all levels of OPA were, but only among those not using anti-hypertensives. The prospective analysis showed occupational lifting to increase the risk of hypertension, among workers aged ≥ 50 years, or reporting light to moderate LTPA. Conclusions This study finds positive associations between occupational lifting and risk for hypertension among workers aged ≥ 50 years. Further research on the association between occupational lifting and precursors of cardiovascular disease are needed before recommendations for occupational lifting and cardiovascular health can be established.

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MODEL UNTUK MENILAI KESIAPAN PEMDA “DKI JAKARTA” DALAM PENGEMBANGAN WILAYAH BERBASIS DUNIA USAHA

Jurnal Sains dan Teknologi Indonesia ◽

10.29122/jsti.v11i1.816 ◽

2012 ◽

Vol 11 (1) ◽

Author(s):

Puguh Suharso

Keyword(s):

Data Gathering ◽

Business Environment ◽

Standard Of Living ◽

Achievement Level ◽

Global Competitiveness ◽

The People ◽

Frame Work ◽

Using Data ◽

Level Of Effort ◽

Research Analysis

Globalisation era is surely passed on and to lead the people of the world into social interactive one another and also economical competitiveness. How far is DKI Jakarta Government preparing to be up against the global competitiveness in the frame-work to manifest improving the standard of living like advanced of society. There are some of indicators to be used as well as criterion to measure an achievement level of effort to be advanced of society, i.e infrastructure which needed by entrepreneur like : permission, taxation, laboract, traffic road, customs and harbor, publics infrastructure servicing, landuse, security condition, business financial access, and business environment condition. It was the research analysis be done by using data gathering from entrepreneur opinion at the operational area. The aim of research analysis is to measure how level of each indicator value has DKI Jakarta Government prepared to be up against the global competitiveness ? The research conclusion says that : DKI Jakarta Government has well enough prepared to be up against the global competitiveness. The weakness indicator is just taxation because its category included in bad (goodless) while the other indicators are well enough. The measuring parameters due to weakness taxationare time necessity for servicing to arrange tax, amount and various of region retribution, amount and various of region tax, and clarity of tax arrangement prucedure.

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Self-selection in a population-based cohort study: impact on health service use and survival for bowel and lung cancer assessed using data linkage

BMC Medical Research Methodology ◽

10.1186/s12874-018-0537-3 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 9

Author(s):

Nicola Creighton ◽

Stuart Purdie ◽

Matthew Soeberg ◽

Richard Walton ◽

Deborah Baker ◽

...

Keyword(s):

Lung Cancer ◽

Cohort Study ◽

Health Service ◽

Service Use ◽

Data Linkage ◽

Population Based ◽

Health Service Use ◽

Self Selection ◽

Using Data

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Logistic regression models for predicting occurrence of terrestrial molluscs in southern Sweden - importance of environmental data quality and model complexity

Ecography ◽

10.1111/j.0906-7590.2004.03553.x ◽

2004 ◽

Vol 27 (1) ◽

pp. 83-93 ◽

Cited By ~ 26

Author(s):

Åke Berg ◽

Ulf Gärdenfors ◽

Ted von Proschwitz

Keyword(s):

Logistic Regression ◽

Data Quality ◽

Regression Models ◽

Environmental Data ◽

Model Complexity ◽

Southern Sweden ◽

Logistic Regression Models

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Bringing the lab to the people: Experimental pain testing in the general population

Scandinavian Journal of Pain ◽

10.1016/j.sjpain.2016.09.010 ◽

2016 ◽

Vol 13 (1) ◽

pp. 142-143

Author(s):

Christopher Sivert Nielsen

Keyword(s):

General Population ◽

Experimental Pain ◽

The People ◽

Pain Testing

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Support for cigarette filter waste policies among US adults

Tobacco Control ◽

10.1136/tobaccocontrol-2020-056451 ◽

2021 ◽

pp. tobaccocontrol-2020-056451

Author(s):

Minal Patel ◽

Alison F Cuccia ◽

Shanell Folger ◽

Adam F Benson ◽

Donna Vallone ◽

...

Keyword(s):

Smoking Status ◽

Population Based ◽

Tobacco Product ◽

Cross Sectional ◽

Cigarette Filter ◽

Logistic Regression Models ◽

Knowledge And Beliefs ◽

Cigarette Butts ◽

Using Data ◽

The Impact

IntroductionLittle is known on whether cigarette filter-related knowledge or beliefs are associated with support for policies to reduce their environmental impact.MethodsA cross-sectional, population-based sample of US adults aged 18–64 years (n=2979) was used to evaluate filter-related knowledge and beliefs by smoking status using data collected between 24 October 2018 and 17 December 2018. Multivariate logistic regression models explored whether these knowledge and belief items were associated with support for two policies, a US$0.75 litter fee and a ban on sales of filtered cigarettes, controlling for demographic characteristics and smoking status.ResultsRegardless of smoking status, 71% did not know plastic was a cigarette filter component and 20% believed filters were biodegradable. Overall, 23% believed filters reduce health harms and 60% believed filters make it easier to smoke; 90% believed cigarette butts are harmful to the environment. Individuals believing cigarette butts harmed the environment were more likely to support a litter fee (adjusted OR (aOR)=2.33, 95% CI: 1.71 to 3.17). Individuals believing that filters are not biodegradable had higher odds of supporting a litter fee (OR=1.47, 95% CI: 1.15 to 1.88). Respondents believing that filters do not make cigarettes less harmful were more likely to support a litter fee (aOR=1.50, 95% CI: 1.20 to 1.88) and filter ban (aOR=2.03, 95% CI: 1.64 to 2.50). Belief that filters make it easier to smoke was associated with decreased support for a filter ban (aOR=0.69, 95% CI: 0.58 to 0.83).ConclusionsComprehensive efforts are needed to educate the public about the impact of cigarette filters in order to build support for effective tobacco product waste policy.

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Trends in end-of- life (EOL) systemic oncologic treatment in contemporary clinical practice: Insights from real-world data.

Journal of Clinical Oncology ◽

10.1200/jco.2020.39.28_suppl.253 ◽

2021 ◽

Vol 39 (28_suppl) ◽

pp. 253-253

Author(s):

Maureen Canavan ◽

Xiaoliang Wang ◽

Mustafa Ascha ◽

Rebecca A. Miksad ◽

Timothy N Showalter ◽

...

Keyword(s):

Cancer Treatment ◽

End Of Life ◽

Real World ◽

Cost Of Care ◽

Real World Data ◽

Logistic Regression Models ◽

Oncolytic Therapy ◽

Immune Therapies ◽

Using Data ◽

Over Time

253 Background: Among patients with cancer, receipt of systemic oncolytic therapy near the end-of-life (EOL) does not improve outcomes and worsens patient and caregiver experience. Accordingly, the ASCO/NQF measure, Proportion Receiving Chemotherapy in the Last 14 Days of Life, was published in 2012. Over the last decade there has been exponential growth in high cost targeted and immune therapies which may be perceived as less toxic than traditional chemotherapy. In this study, we identified rates and types of EOL systemic therapy in today’s real-world practice; these can serve as benchmarks for cancer care organizations to drive improvement efforts. Methods: Using data from the nationwide Flatiron Health electronic health record (EHR)-derived de-identified database we included patients who died during 2015 through 2019, were diagnosed after 2011, and who had documented cancer treatment. We identified the use of aggressive EOL systemic treatment (including, chemotherapy, immunotherapy, and combinations thereof) at both 30 days and 14 days prior to death. We estimated standardized EOL rates using mixed-level logistic regression models adjusting for patient and practice-level factors. Year-specific adjusted rates were estimated in annualized stratified analysis. Results: We included 57,127 patients, 38% of whom had documentation of having received any type of systemic cancer treatment within 30 days of death (SD: 5%; range: 25% - 56%), and 17% within 14 days of death (SD: 3%; range: 10% - 30%). Chemotherapy alone was the most common EOL treatment received (18% at 30 days, 8% at 14 days), followed by immunotherapy (± other treatment) (11% at 30 days, 4% at 14 days). Overall rates of EOL treatment did not change over the study period: treatment within 30 days (39% in 2015 to 37% in 2019) and within 14 days (17% in 2015 to 17% in 2019) of death. However, the rates of chemotherapy alone within 30 days of death decreased from 24% to 14%, and within 14 days, from 10% to 6% during the study period. In comparison, rates for immunotherapy with chemotherapy (0%-6% for 30 days, 0% -2% for 14 days), and immunotherapy alone or with other treatment types (4%-13% for 30 days, 1%-4% for 14 days) increased over time for both 30 and 14 days. Conclusions: End of life systemic cancer treatment rates have not substantively changed over time despite national efforts and expert guidance. While rates of traditional chemotherapy have decreased, rates of costly immunotherapy and targeted therapy have increased, which has been associated with higher total cost of care and overall healthcare utilization. Future work should examine the drivers of end-of-life care in the era of immune-oncology.

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