scholarly journals Harlequin fetus in a twin sibling: a rare case report

2021 ◽  
Vol 29 ◽  
Author(s):  
Rabia Merve Palalıoğlu ◽  
Halil Ibrahim Erbıyık ◽  
Aytakin Mahammadaliyeva ◽  
Batuhan Palalıoğlu ◽  
Rojda Bayar

Objective: Ichthyosis is a heterogeneous group of disorders characterized by hereditary keratinization of the skin. Ichthyosis means “fish skin.” There are at least 20 different types of ichthyosis. Among these, Harlequin-type ichthyosis is a rare, but often fatal, special form of congenital ichthyosis. Rates are higher in certain populations with higher probability of inbreeding. Babies are born with parchment-paper-like transparent membrane covering the whole body. Complications such as dehydration, prematurity, sepsis, electrolyte imbalance, and pneumonia could occur, adversely affecting survival. Case(s): We presented an ichthyosis case born from a dizygotic pregnancy of a Syrian woman living as a refugee in Turkey. Despite all the medical procedures performed in the neonatal intensive care unit, the baby who was diagnosed with Harlequin type ichthyosis died on the second postpartum day. Conclusion: Few cases of ichthyosis in twins have been reported. It is very important to benefit from prenatal screening and genetic counseling in the early diagnosis of such inherited, rare and fatal diseases.

2021 ◽  
Vol 35 (3) ◽  
pp. 406-414
Author(s):  
Yoko Satoh ◽  
Masami Kawamoto ◽  
Kazunori Kubota ◽  
Koji Murakami ◽  
Makoto Hosono ◽  
...  

AbstractBreast positron emission tomography (PET) has had insurance coverage when performed with conventional whole-body PET in Japan since 2013. Together with whole-body PET, accurate examination of breast cancer and diagnosis of metastatic disease are possible, and are expected to contribute significantly to its treatment planning. To facilitate a safer, smoother, and more appropriate examination, the Japanese Society of Nuclear Medicine published the first edition of practice guidelines for high-resolution breast PET in 2013. Subsequently, new types of breast PET have been developed and their clinical usefulness clarified. Therefore, the guidelines for breast PET were revised in 2019. This article updates readers as to what is new in the second edition. This edition supports two different types of breast PET depending on the placement of the detector: the opposite-type (positron emission mammography; PEM) and the ring-shaped type (dedicated breast PET; dbPET), providing an overview of these scanners and appropriate imaging methods, their clinical applications, and future prospects. The name “dedicated breast PET” from the first edition is widely used to refer to ring-shaped type breast PET. In this edition, “breast PET” has been defined as a term that refers to both opposite- and ring-shaped devices. Up-to-date breast PET practice guidelines would help provide useful information for evidence-based breast imaging.


Genes ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 506
Author(s):  
Alexander Ereskovsky ◽  
Ilya E. Borisenko ◽  
Fyodor V. Bolshakov ◽  
Andrey I. Lavrov

While virtually all animals show certain abilities for regeneration after an injury, these abilities vary greatly among metazoans. Porifera (Sponges) is basal metazoans characterized by a wide variety of different regenerative processes, including whole-body regeneration (WBR). Considering phylogenetic position and unique body organization, sponges are highly promising models, as they can shed light on the origin and early evolution of regeneration in general and WBR in particular. The present review summarizes available data on the morphogenetic and cellular mechanisms accompanying different types of WBR in sponges. Sponges show a high diversity of WBR, which principally could be divided into (1) WBR from a body fragment and (2) WBR by aggregation of dissociated cells. Sponges belonging to different phylogenetic clades and even to different species and/or differing in the anatomical structure undergo different morphogeneses after similar operations. A common characteristic feature of WBR in sponges is the instability of the main body axis: a change of the organism polarity is described during all types of WBR. The cellular mechanisms of WBR are different across sponge classes, while cell dedifferentiations and transdifferentiations are involved in regeneration processes in all sponges. Data considering molecular regulation of WBR in sponges are extremely scarce. However, the possibility to achieve various types of WBR ensured by common morphogenetic and cellular basis in a single species makes sponges highly accessible for future comprehensive physiological, biochemical, and molecular studies of regeneration processes.


Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 636 ◽  
Author(s):  
Rossella Cianci ◽  
Laura Franza ◽  
Maria Grazia Massaro ◽  
Raffaele Borriello ◽  
Francesco De Vito ◽  
...  

Vaccinations are among the most effective medical procedures and have had an incredible impact on almost everyone’s life. One of the populations that can benefit the most from them are elderly people. Unfortunately, in this group, vaccines are less effective than in other groups, due to immunosenescence. The immune system ages like the whole body and becomes less effective in responding to infections and vaccinations. At the same time, immunosenescence also favors an inflammatory microenvironment, which is linked to many conditions typical of the geriatrics population. The microbiota is one of the key actors in modulating the immune response and, in this review, we discuss the current evidence on the role of microbiota in regulating the immune response to vaccines, particularly in elderly people.


Author(s):  
Hyoung-gon (Frank) Ryou ◽  
Peter W Johnson

A number of studies have shown an association between whole-body vibration (WBV) exposure and the onset and development of low back pain among professional vehicle operators. This study measured WBV exposures from 12 drivers who operated four different types of solid waste collecting trucks during part of their regular work shift. The daily average weighted A(8), vibration dose value VDV(8), and vector sum A(8) and VDV(8) exposures were analyzed and compared across the solid waste collecting trucks. Study result showed that the majority of A(8) and all of the VDV(8) predominant axis exposures were above International Organization for Standardization (ISO) daily vibration action limit (A(8) = 0.5 m/s2, VDV(8) = 9.1 m/s1.75). Based on the predominant axis and vector sum exposures, most of the trucks reached the daily vibration action limits before 8-hours. When compared to the predominant axis A(8) exposures, the predominant axis VDV(8) exposures reduced the acceptable solid waste collecting truck operating times on average by over 4 hours. Our study results demonstrated that these solid waste collecting truck operators were exposed to high levels of both continuous and impulsive WBV exposures, with the impulsive WBV exposures indicating that they may pose a greater risk to the driver’s health.


1984 ◽  
Vol 32 (1) ◽  
pp. 1-6 ◽  
Author(s):  
S Sjögren

Freeze-dried sagittal, whole-body sections of 10-day-old rats were incubated for lactic dehydrogenase (LDH) using different media in the presence of the inhibitors urea and fluoropyruvate. Phenazine methosulfate (PMS) and menadione, which are regularly used in current histochemical media and are believed to promote the demonstration of LDH activity, were also added and shown to be insufficient for the demonstration of total LDH activity, and PMS even seemed to have an inhibitory effect on LDH activity in oral epithelium. However, cumulated data from the different incubations show that the oral epithelium of developing rats may contain two different types of LDH, one in the basal cells with possibly aerobic characteristics, and another in the spinosum/granulosum cells with anaerobic characteristics.


Ból ◽  
2017 ◽  
Vol 18 (1) ◽  
pp. 37-43
Author(s):  
Kamil Krzyżanowski ◽  
Daniel Ślęzak ◽  
Andrzej Basiński ◽  
Przemysław Żuratyński ◽  
Paulina Buca

In last time major changes in the system of National Medical Rescue (Państwowe Ratownictwo Medyczne, PRM) occurred. Changes between the others concerned increasing permissions of medical rescuers. For a long time we discussed wide spectrum of actions and autonomy of this professional group and in latest term benefit package of this group was additionally expanded. Is such a varied list of medical procedures, in it pharmacotherapy, is a proper growth of system is subject at issue. Authors of the article decided to look into selected fragments of actions of the system of Medical Rescue and analyze one of import_ant elements of departure team actions, namely relieving pain of injured after the injury. Asking following questions is justified: Is increasing the pool of permissions caused by depleting previous therapeutical possibilities, or were there other reasons to add changes; Is releasing pain on prehospital level enough? Should the attention be focused on this subject and possibly implement repair procedures and educative? To define issues above, medical documentation of trustees of medical teams on the area of Pomeranian Voivodeship were analyzed. Among all provided documents, the ones in which reason of the call was injury were chosen. Tens of thousands cards with different types of injuries were obtained, insulated, multiple and generalized injuries. In how many cases, the procedure of pain relieving were applied was examined and what medicines were used the most. Unfortunately as seen on the presented statistics, only small percentage of cases there were tries of decreasing complaints of injured despite the wide amount available resources. These preliminary studies show the necessity of inputting repair procedures in terms of relieving the pain of injured after injuries by departure teams of Medical Rescue.


2021 ◽  
Vol 9 (4) ◽  
pp. 794-798
Author(s):  
Anubha Jain ◽  
Mukesh Kumar Gupta

Karnanada considered as illness caused due to vitiated VataDosha in which a person hears different types of sound in absence of any relevant external stimulus. Now days, it can be considered as tinnitus, a disease with mul- tifactorial etiology. It may be concerned with unhealthy condition of only ear, ear with head disease, only head disease or may be associated with general body condition. In tinnitus patient got ringing, buzzing or other type of sound in one or both ears which might be constant and inconstant often associated with hearing loss. In Ayurveda it is described as preliminary symptoms of hearing loss, which without treatment or with incomplete or improper treatment will progress towards hearing loss. In present scenario of electronic devices which produces electro- magnetic waves (which are harmful to ear including whole body organs), number of such type of cases are in- creasing frequently worldwide. Causes of tinnitus according to modern medicine is unclear or having multiple etiologies therefore treatment guideline of tinnitus in modern practice is not definite hence prognosis of disease also remains uncertain. But in Ayurveda prognosis and line of treatment of Karnanada is mentioned and we can achieve good and satisfactory result. Keywords: Karnanada, Tinnitus, Ayurveda


1994 ◽  
Vol 14 (1) ◽  
pp. 22-25 ◽  
Author(s):  
Patrizia Zaramella ◽  
Barbara Andreetta ◽  
Giovanni Franco Zanon ◽  
Luisa Murer ◽  
Giovanni Montini ◽  
...  

Objective To report the complications and outcome of 10 newborns affected by acute renal failure (ARF), treated by continuous peritoneal dialysis (CPD). Design All newborns admitted for tertiary treatment to the Neonatal Intensive Care Unit of the University of Padova, who underwent CPD between February 1986 and December 1990, were analyzed retrospectively. Patients Ten newborns (mean weight 2077 g, range 540–4930 g) received CPD, 6 of whom were preterm. All the survivors completed the study. Interventions A number 9,5 French Tenckhoff catheter was used, and a closed circuit was created by means of a modified continuous ambulatory peritoneal dialysis (CAPD) technique. The mean duration of dialytic therapy was 7 days. Results At the end of the dialytic period, 7 of the 10 patients had normal serum potassium and sodium values. CPD produced two different types of complications: leakage of the dialytic fluid in very low weight newborns and one episode of peritonitis during a chronic dialysis treatment. Six died of severe respiratory failure (in no case, however, was this attributable to ARF or CPD procedure). All but one of the survivors regained normal renal function. The only exception necessitated a kidney trans plant. Conclusion We believe that this technique, although invasive, improves the outcome of both preterm and low birth weight newborns affected by ARF.


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