scholarly journals AN AYURVEDIC REVIEW OF KARNANADA W.S.R. TINNITUS

2021 ◽  
Vol 9 (4) ◽  
pp. 794-798
Author(s):  
Anubha Jain ◽  
Mukesh Kumar Gupta
Keyword(s):  
Hearing Loss ◽  
Body Condition ◽  
Electronic Devices ◽  
Treatment Guideline ◽  
Modern Medicine ◽  
Whole Body ◽  
Tinnitus Patient ◽  
General Body ◽  
Different Types ◽  
Electro Magnetic

Karnanada considered as illness caused due to vitiated VataDosha in which a person hears different types of sound in absence of any relevant external stimulus. Now days, it can be considered as tinnitus, a disease with mul- tifactorial etiology. It may be concerned with unhealthy condition of only ear, ear with head disease, only head disease or may be associated with general body condition. In tinnitus patient got ringing, buzzing or other type of sound in one or both ears which might be constant and inconstant often associated with hearing loss. In Ayurveda it is described as preliminary symptoms of hearing loss, which without treatment or with incomplete or improper treatment will progress towards hearing loss. In present scenario of electronic devices which produces electro- magnetic waves (which are harmful to ear including whole body organs), number of such type of cases are in- creasing frequently worldwide. Causes of tinnitus according to modern medicine is unclear or having multiple etiologies therefore treatment guideline of tinnitus in modern practice is not definite hence prognosis of disease also remains uncertain. But in Ayurveda prognosis and line of treatment of Karnanada is mentioned and we can achieve good and satisfactory result. Keywords: Karnanada, Tinnitus, Ayurveda

Rheumatoid Arthritis: History, Stages, Epidemiology, Pathogenesis, Diagnosis and Treatment

2017 ◽  
Vol 9 (02) ◽  
Author(s):  
Abeer Fauzi Al-Rubaye ◽  
Mohanad Jawad Kadhim ◽  
Imad Hadi Hameed
Keyword(s):  
Rheumatoid Arthritis ◽  
Medicinal Plants ◽  
Systemic Disease ◽  
Modern Medicine ◽  
Whole Body ◽  
Internal Organs ◽  
Synthetic Drugs ◽  
Relieve Pain ◽  
Medicinal Treatment ◽  
Natural Drugs

The pharmacological mechanisms of the medicinal plants traditionally used for RA in Persian medicine are discussed in the current review. Further investigations are mandatory to focus on bioefficacy of these phytochemicals for finding novel natural drugs. Rheumatoid arthritis is chronic, progressive, disabling autoimmune disease characterized by systemic inflammation of joints, damaging cartilage and bone around the joints. It is a systemic disease which means that it can affect the whole body and internal organs such as lungs, heart and eyes. Although numbers of synthetic drugs are being used as standard treatment for rheumatoid arthritis but they have adverse effect that can compromise the therapeutic treatment. Unfortunately, there is still no effective known medicinal treatment that cures rheumatoid arthritis as the modern medicine can only treat the symptoms of this disease that means to relieve pain and inflammation of joints. It is possible to use the herbs and plants in various forms in order to relieve the pain and inflammation in the joints. There are so many medicinal plants that have shown anti rheumatoid arthritis properties. So the plants and plant product with significant advantages are used for the treatment of rheumatoid arthritis. The present review is focused on the medicinal plants having anti rheumatoid arthritis activity

scholarly journals A novel case of concurrent occurrence of demyelinating-polyneuropathy-causing PMP22 duplication and SOX10 gene mutation producing severe hypertrophic neuropathy

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nozomu Matsuda ◽  
Koushi Ootsuki ◽  
Shunsuke Kobayashi ◽  
Ayaka Nemoto ◽  
Hitoshi Kubo ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Neuromuscular Disorders ◽  
Whole Body ◽  
Congenital Hearing Loss ◽  
Severe Phenotype ◽  
Demyelinating Neuropathy ◽  
Magnetic Resonance Neurography ◽  
Peripheral Myelin Protein 22 ◽  
Hypertrophic Neuropathy

Abstract Background Hereditary motor and sensory neuropathy, also referred to as Charcot–Marie–Tooth disease (CMT), is most often caused by a duplication of the peripheral myelin protein 22 (PMP22) gene. This duplication causes CMT type 1A (CMT1A). CMT1A rarely occurs in combination with other hereditary neuromuscular disorders. However, such rare genetic coincidences produce a severe phenotype and have been reported in terms of “double trouble” overlapping syndrome. Waardenburg syndrome (WS) is the most common form of a hereditary syndromic deafness. It is primarily characterized by pigmentation anomalies and classified into four major phenotypes. A mutation in the SRY sex determining region Y-box 10 (SOX10) gene causes WS type 2 or 4 and peripheral demyelinating neuropathy, central dysmyelinating leukodystrophy, WS, and Hirschsprung disease. We describe a 11-year-old boy with extreme hypertrophic neuropathy because of a combination of CMT1A and WS type 2. This is the first published case on the co-occurrence of CMT1A and WS type 2. Case presentation The 11-year-old boy presented with motor developmental delay and a deterioration in unstable walking at 6 years of age. In addition, he had congenital hearing loss and heterochromia iridis. The neurological examination revealed weakness in the distal limbs with pes cavus. He was diagnosed with CMT1A by the fluorescence in situ hybridization method. His paternal pedigree had a history of CMT1A. However, no family member had congenital hearing loss. His clinical manifestation was apparently severe than those of his relatives with CMT1A. In addition, a whole-body magnetic resonance neurography revealed an extreme enlargement of his systemic cranial and spinal nerves. Subsequently, a genetic analysis revealed a heterozygous frameshift mutation c.876delT (p.F292Lfs*19) in the SOX10 gene. He was eventually diagnosed with WS type 2. Conclusions We described a patient with a genetically confirmed overlapping diagnoses of CMT1A and WS type 2. The double trouble with the genes created a significant impact on the peripheral nerves system. Severe phenotype in the proband can be attributed to the cumulative effect of mutations in both PMP22 and SOX10 genes, responsible for demyelinating neuropathy.

scholarly journals Clinical practice guidelines for high-resolution breast PET, 2019 edition

2021 ◽  
Vol 35 (3) ◽  
pp. 406-414
Author(s):  
Yoko Satoh ◽  
Masami Kawamoto ◽  
Kazunori Kubota ◽  
Koji Murakami ◽  
Makoto Hosono ◽  
...  
Keyword(s):  
High Resolution ◽  
Practice Guidelines ◽  
Breast Imaging ◽  
Japanese Society ◽  
Insurance Coverage ◽  
Whole Body ◽  
Positron Emission Mammography ◽  
Dedicated Breast Pet ◽  
Positron Emission ◽  
Different Types

AbstractBreast positron emission tomography (PET) has had insurance coverage when performed with conventional whole-body PET in Japan since 2013. Together with whole-body PET, accurate examination of breast cancer and diagnosis of metastatic disease are possible, and are expected to contribute significantly to its treatment planning. To facilitate a safer, smoother, and more appropriate examination, the Japanese Society of Nuclear Medicine published the first edition of practice guidelines for high-resolution breast PET in 2013. Subsequently, new types of breast PET have been developed and their clinical usefulness clarified. Therefore, the guidelines for breast PET were revised in 2019. This article updates readers as to what is new in the second edition. This edition supports two different types of breast PET depending on the placement of the detector: the opposite-type (positron emission mammography; PEM) and the ring-shaped type (dedicated breast PET; dbPET), providing an overview of these scanners and appropriate imaging methods, their clinical applications, and future prospects. The name “dedicated breast PET” from the first edition is widely used to refer to ring-shaped type breast PET. In this edition, “breast PET” has been defined as a term that refers to both opposite- and ring-shaped devices. Up-to-date breast PET practice guidelines would help provide useful information for evidence-based breast imaging.

scholarly journals Whole-Body Regeneration in Sponges: Diversity, Fine Mechanisms, and Future Prospects

Genes ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 506
Author(s):  
Alexander Ereskovsky ◽  
Ilya E. Borisenko ◽  
Fyodor V. Bolshakov ◽  
Andrey I. Lavrov
Keyword(s):  
Single Species ◽  
Whole Body ◽  
Phylogenetic Position ◽  
Main Body ◽  
Regenerative Processes ◽  
Cellular Mechanisms ◽  
Different Types ◽  
Dissociated Cells ◽  
Shed Light ◽  
Regeneration Processes

While virtually all animals show certain abilities for regeneration after an injury, these abilities vary greatly among metazoans. Porifera (Sponges) is basal metazoans characterized by a wide variety of different regenerative processes, including whole-body regeneration (WBR). Considering phylogenetic position and unique body organization, sponges are highly promising models, as they can shed light on the origin and early evolution of regeneration in general and WBR in particular. The present review summarizes available data on the morphogenetic and cellular mechanisms accompanying different types of WBR in sponges. Sponges show a high diversity of WBR, which principally could be divided into (1) WBR from a body fragment and (2) WBR by aggregation of dissociated cells. Sponges belonging to different phylogenetic clades and even to different species and/or differing in the anatomical structure undergo different morphogeneses after similar operations. A common characteristic feature of WBR in sponges is the instability of the main body axis: a change of the organism polarity is described during all types of WBR. The cellular mechanisms of WBR are different across sponge classes, while cell dedifferentiations and transdifferentiations are involved in regeneration processes in all sponges. Data considering molecular regulation of WBR in sponges are extremely scarce. However, the possibility to achieve various types of WBR ensured by common morphogenetic and cellular basis in a single species makes sponges highly accessible for future comprehensive physiological, biochemical, and molecular studies of regeneration processes.

scholarly journals “Trividh Pariksha-Ayurvedic and Modern Perspective.”

2020 ◽  
Vol 4 (05) ◽  
Author(s):  
Dubey Shivanikumari Rajesh
Keyword(s):  
Physical Examination ◽  
Modern Medicine ◽  
History Taking ◽  
Important Place ◽  
Different Types ◽  
Factual Data ◽  
Radiological Examinations ◽  
Or History ◽  
Modern Perspective

The term Pariksha is used for the Examinations done on patient for appropriate diagnosis. The prime duty of any Physician is to diagnose the ailment of the patient. The diagnosis cannot be done just on basis of one type of examination. In Ayurveda different types of examinations have been mentioned which were and still are useful in diagnosing the various diseases in patients. Two basic processes. 1) Interrogation or history taking or anamnesis , 2)Physical examination [1]and at present time pathological and radiological examinations are the basic requirements  by which factual data of the diseases are collected. Ayurveda has mentioned in detail about the various Parikshas which have been categorized in Trividh , Panchvidh, Shadvidh , Ashtavidha Pariksha have been mentioned. Here Trividh Pariksha –Darshan, Sparshan and Prashna and its all aspects will be discussed in perspective of both Ayurveda and Modern medicine. These basic methods which are practiced today, with modern terminologies have one of the important place in Ayurvedic Nidan (diagnosis).

scholarly journals Vowel production of Mandarin-speaking hearing aid users with different types of hearing loss

PLoS ONE ◽  
2017 ◽  
Vol 12 (6) ◽  
pp. e0178588 ◽  
Author(s):  
Yu-Chen Hung ◽  
Ya-Jung Lee ◽  
Li-Chiun Tsai
Keyword(s):  
Hearing Loss ◽  
Hearing Aid ◽  
Vowel Production ◽  
Different Types

The Exchange of Labelled Sodium in the Larva of Aedes Aegypti L

1954 ◽  
Vol 31 (3) ◽  
pp. 386-401 ◽  
Author(s):  
JOHN E. TREHERNE
Keyword(s):  
Aedes Aegypti ◽  
Body Surface ◽  
External Medium ◽  
Whole Body ◽  
Effect Of Temperature ◽  
Potassium Ions ◽  
Distilled Water ◽  
General Body ◽  
Anal Papillae

1. The exchange of labelled sodium between the external medium and the haemolymph and whole body has been investigated in the larva of Aedes aegypti. The time for half exchange was of the order of 62 hr. 2. It was found that most of the exchange of labelled sodium occurred through the anal papillae, although smaller amounts enter the haemolymph through the gut and general body surface. Transfer constants have been used to describe the resultant turnover of labelled sodium in the whole system. 3. The rate of uptake of sodium was independent of the external concentrations used in these experiments. 4. Potassium ions do not compete with sodium for uptake, which suggests that separate mechanisms are responsible for the accumulation of these two ions. 5. Larvae were able to retain the sodium in the haemolymph, with relatively little loss, in glass-distilled water. 6. The effect of temperature on the rate of uptake of labelled sodium has been investigated.

4. Measurement in the life sciences, medicine, and health

2016 ◽  
pp. 60-72
Author(s):  
David J. Hand
Keyword(s):  
Biological Systems ◽  
Life Sciences ◽  
Modern Medicine ◽  
Pain Anxiety ◽  
Measurement Issues ◽  
Distribution Of Values ◽  
Different Types ◽  
Biological Domain ◽  
Medical Measurement ◽  
Biological Organisms

Biological systems pose particularly challenging measurement issues. This is partly because the biological domain is characterized by complexity and diversity. As a consequence, the results of measuring biological organisms will often result in a distribution of values. A further complication in medicine is that much measurement is of attributes or characteristics relating to internal or subjective phenomena such as of pain, anxiety, and dizziness. ‘Measurement in the life sciences, medicine, and health’ considers the scope of medical measurement, how to measure patients, and how to measure the health of populations. In modern medicine, there are many different reasons for taking a measurement, and hence many different types of measurement.

Comparison of auditory steady-state response and click-evoked auditory brain response in infants with different types and degrees of hearing loss

2019 ◽  
Vol 140 (2) ◽  
pp. 116-121
Author(s):  
Xiaoli Wang ◽  
Yangyang Cheng ◽  
Jing Shi ◽  
Xiangyun Sheng ◽  
Dan Wu ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Steady State ◽  
Steady State Response ◽  
Brain Response ◽  
State Response ◽  
Auditory Steady State Response ◽  
Different Types

scholarly journals Modeling Y-Linked Pedigrees through Branching Processes

Mathematics ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 256
Author(s):  
Miguel González ◽  
Cristina Gutiérrez ◽  
Rodrigo Martínez
Keyword(s):  
Hearing Loss ◽  
Asymptotic Behavior ◽  
Gibbs Sampler ◽  
Mutant Allele ◽  
Branching Process ◽  
Branching Processes ◽  
Dominant Allele ◽  
Linked Gene ◽  
Different Types ◽  
The Mean

A multidimensional two-sex branching process is introduced to model the evolution of a pedigree originating from the mutation of an allele of a Y-linked gene in a monogamous population. The study of the extinction of the mutant allele and the analysis of the dominant allele in the pedigree is addressed on the basis of the classical theory of multi-type branching processes. The asymptotic behavior of the number of couples of different types in the pedigree is also derived. Finally, using the estimates of the mean growth rates of the allele and its mutation provided by a Gibbs sampler, a real Y-linked pedigree associated with hearing loss is analyzed, concluding that this mutation will persist in the population although without dominating the pedigree.

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