scholarly journals To Study the Prevalence of Osteopenia and Osteoporosis in Patients with COPD and to Correlate Severity of COPD with Prevalence of Osteopenia and Osteoporosis

2021 ◽  
Vol 08 (02) ◽  
pp. 1-5
Author(s):  
Pratap Singh ◽  
Keyword(s):  
Risk Factors ◽  
Tertiary Care ◽  
Pulmonary Complications ◽  
Stage Iii ◽  
Smoking History ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Mineral Density ◽  
Bone Mass Loss ◽  
Copd Patients

Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory airway disease characterized by both pulmonary and systemic inflammatory response and associated extra-pulmonary complications. Female gender, age and smoking are common pathogenic risk factors for both COPD and osteoporosis. Many other factors like low daily physical activity, chronic malnutrition, hypogonadism, vitamin D deficiency and chronic steroid therapy are risk factors for osteoporosis. Objectives: The study was done to evaluate the prevalence of osteopenia and osteoporosis in patients of COPD and to correlate the severity of COPD with osteopenia/ osteoporosis. Material & Method: The study was conducted at a tertiary care hospital in Delhi after ethical clearance from institutional review board. Total of 76 patients of both genders were taken. COPD diagnosis and staging was done as per Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. Bone mineral density (BMD) was evaluated by DEXA scan in all patients. All data was entered in preformed data sheets. Statistical analysis for association of COPD with osteoporosis was done by chi-square test. Result: Mostly patients were having either osteopenia or osteoporosis, only 6% patients were having normal BMD. COPD stage III-IV were having significant bone mass loss. Those having long smoking history were more osteoporotic as compared to others. Conclusion: There is a very high prevalence of osteopenia and osteoporosis in COPD patients especially those with prolonged smoking history, GOLD stage III-IV. 35.5% of COPD patients had osteopenia and 57.9 % had osteoporosis.

Prevalence and risk factors of osteoporosis in Chronic Obstructive Pulmonary Disease (COPD) patients from Central India.

2017 ◽  
Vol 6 (04) ◽  
pp. 5350
Author(s):  
Sonali Trivedi ◽  
Hetal Rudani ◽  
Subodh K. Kirolokar
Keyword(s):  
Risk Factors ◽  
Tertiary Care Hospital ◽  
Univariate Analysis ◽  
Tertiary Care ◽  
Central India ◽  
Whole Body ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Severity Of Disease ◽  
Copd Patients

The prevalence of osteoporosis in patients with COPD is high and potentially essential. To study prevalence and various risk factors contributing to osteoporosis in COPD patients. The present study is prospective cross sectional study carried out on 80 stable COPD patients attending tertiary care hospital in central India. After taking written consent & detailed clinical history consisting questionnaire about the risk factors, spirometry was done to stage the severity of COPD. DEXA scan of whole body was performed using fan beam X-ray bone densitometer to determine osteoporosis. Chi-square test was used to determine the association between COPD and osteoporosis. Univariate logistic regression was used to analyze the risk factors for developing osteoporosis. In the present study, the overall prevalence of low BMD was found to be 92.5% in COPD patients showing equal prevalence (46.25%) for osteoporosis and osteopenia. The duration & severity of disease along with steroid intake were found to be risk factors of osteoporosis in univariate analysis with risk ratio of 1.32 (95% CI 1.06-1.64), 1.75 (1.11-2.75) and 1.40 (1.00-1.97) respectively (p value <0.05). The prevalence of low BMD was very high in COPD patients at a tertiary care hospital of central India. Duration & severity of disease along with steroid intake were found to be risk factor for osteoporosis in univariate analysis.

scholarly journals Recurrent Emergency Department Users: Two Categories with Different Risk Profiles

2019 ◽  
Vol 8 (3) ◽  
pp. 333 ◽  
Author(s):  
Ksenija Slankamenac ◽  
Meret Zehnder ◽  
Tim Langner ◽  
Kathrin Krähenmann ◽  
Dagmar Keller
Keyword(s):  
Risk Factors ◽  
Emergency Department ◽  
Emergency Services ◽  
Hospital Admissions ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Co Morbidity ◽  
Ed Visits ◽  
Morbidity Index

Recurrent emergency department (ED) visits are responsible for an increasing proportion of overcrowding. Therefore, our aim was to investigate the characteristics and prevalence of recurrent ED visitors as well as to determine risk factors associated with multiple ED visits. ED patients visiting the ED of a tertiary care hospital at least four times consecutively in 2015 were enrolled. Of 33,335 primary ED visits, 1921 ED visits (5.8%) were performed by 372 ED patients who presented in the ED at least four times within the one-year period. Two different categories of recurrent ED patients were identified: repeated ED users presenting always with the same symptoms and frequent ED visitors who were suffering from different symptoms on each ED visit. Repeated ED users had more ED visits (p < 0.001) and needed more hospital admissions (p < 0.010) compared to frequent ED users. Repeated ED users visited the ED more likely due to symptoms from chronic obstructive pulmonary diseases (p < 0.001) and mental disorders (p < 0.001). In contrast, frequent ED patients showed to be at risk for multiple ED visits when being disabled (p = 0.001), had an increased Charlson co-morbidity index (p = 0.004) or suffering from rheumatic diseases (p < 0.001). A small number of recurrent ED visitors determines a relevant number of ED visits with a relevance for and impact on patient centred care and emergency services. There are two categories of recurrent ED users with different risk factors for multiple ED visits: repeated and frequent. Therefore, multi-professional follow-up care models for recurrent ED patients are needed to improve patients’ needs, quality of life as well as emergency services.

scholarly journals Clinical characteristics and factors influencing the outcome of hospitalised COVID-19 patients in a semi-urban primary healthcare center

2021 ◽  
Vol 14 (2) ◽  
pp. 42-54
Author(s):  
Wasim Md Mohosin Ul Haque ◽  
Chinmay Saha Podder ◽  
Nandini Chowdhury ◽  
Md Mohim Ibne Sina ◽  
SKM Shameem Kawser ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adverse Outcome ◽  
Severe Disease ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Rt Pcr ◽  
District Health ◽  
Factors Associated ◽  
Negative Outcome

Background and objectives: Various new manifestations and risk factors for COVID-19 have been unveiled in the course of the current pandemic. Understanding the clinical spectrums as well as the risk factors associated with the adverse outcome of the disease is critical to combat this pandemic. This study was conducted to identify the clinical features, overall outcome and the factors associated with adverse outcome of the hospitalised COVID-19 patients in a semi-urban healthcare setting. Methods: This study was conducted at Debidwar Upazila (sub-district) Health Complex under the Cumilla district from April 2020 to October 2020. Reverse transcriptase-polymerase chain reaction (RT-PCR) positive COVID-19 patients, aged 18 years and above, admitted at the Health Complex were enrolled in the study. All patients were followed till their recovery, referral or death. The data were collected in a pre-designed semi-structured questionnaire that included demographic, epidemiological, clinical and laboratory parameters. Result: Out of 50 RT-PCR positiveCOVID-19 adult participants, 30 (60%) were males and 20 (40%) were females. Twenty-four percent, 36%, and 40% of the patients had mild, moderate and severe disease respectively. The most common clinical symptom was fever (96%), followed by cough (86%) and shortness of breath (60%). Hypertension (54%), diabetes mellitus (40%), bronchial asthma (20%) and chronic obstructive pulmonary disease (COPD, 14%) were the major co-morbid conditions. Of the total cases, 2 (4%) died and 8 (16%) required referral to tertiary care hospital while 40 (80%) recovered. COPD was associated with poor outcome (OR 19; 95% CI: 2.88, 125.31; p < 0.05). Smokers were 7 times more likely to exhibit the negative outcome than non-smokers (95% CI: 1.52, 32.33; p < 0.05). Conclusion: In this study, COPD was associated with a negative outcome. Further study with larger sample should be carried out to determine the spectrum of risk factors. Ibrahim Med. Coll. J. 2020; 14(2): 42-54

scholarly journals Assessment of Disease Knowledge, Medication Adherence, HRQOL in COPD Patients at a South Indian Tertiary Care Hospital

2021 ◽  
Vol 11 (5) ◽  
pp. 57-60
Author(s):  
S. Padmakar ◽  
R.B. Purandhar Chakravarthy ◽  
Prodduturu Sai Karthik ◽  
B.U. Charitha ◽  
T. Harini ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Obstructive Pulmonary Disease ◽  
Disease Knowledge ◽  
Adherence To Medication ◽  
South Indian ◽  
Copd Patients ◽  
Ethical Committee Approval

Introduction: Chronic obstructive pulmonary disease (COPD) is a progressive, life-threatening disease of the lungs, gradually causes breathlessness and predisposes to exacerbations and serious illness. The main objectives of the study are to evaluate disease knowledge, medication adherence, and health-related quality of life among COPD patients. Methodology: A Hospital-based, single-entered prospective observational study was conducted at a government general hospital, Andhra Pradesh. India after ethical committee approval. This study was conducted for 6 months with a sample size of 80 patients. Results: According to our study, the majority of the patients 36 (45%) don’t have disease knowledge, where a few numbers of patients 7 (8.75%) is having disease knowledge as per BCKQ score values. 11.25% of patients have the lowest MMAS scores whereas 58.75% were found to have higher MMAS scores and 37.5% of total patients have higher CAT scores, and 12.5% of patients have lower CAT scores. Conclusion: We found that majority of the patients have poor disease knowledge, lower adherence to medication regimens, and substandard HRQOL. Keywords: COPD knowledge, medication adherence, and HRQOL.

scholarly journals Degree of Pulmonary Hypertension in Patients of COPD Attending a Tertiary Care Hospital

2021 ◽  
Vol 6 (05) ◽  
pp. 312-315
Author(s):  
Afshan Ali Shaik ◽  
Durga Lawande
Keyword(s):  
Pulmonary Hypertension ◽  
Tertiary Care ◽  
Systolic Pressure ◽  
Biomass Fuel ◽  
Pulmonary Artery Systolic Pressure ◽  
Chronic Obstructive ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Copd Patients ◽  
Increased Risk

Introduction: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality in India. The development of pulmonary hypertension (PH) in COPD adversely affects survival and exercise capacity and is associated with an increased risk of severe acute exacerbation. Aims and Objectives: Present study aimed to describe the distribution of echocardiographically assessed pulmonary artery systolic pressure in the COPD patients attending pulmonary medicine OPD, to estimate the proportion of PH among such patients and to identify associated factors. Methodology: This Cross sectional study was done on 145 patients of COPD fulfilling the inclusion criteria were included in this study. These patients were evaluated for the presence of PH using chest X-ray, 2D-Echocrdiography and electrocardiogram. Results: Pulmonary hypertension was present in 17 (29.8%) patients with moderate, 36 (60%) with severe and 18 (72%) with very severe COPD. Mild PH was seen in 52(73%), moderate in 11(15.4%) and severe in 8(11.2%) patients. Patient exposed to both smoking and biomass fuel smoke had more frequent occurrence of PH (56.8%) as compared to exposure to single risk factor of either tobacco smoke (47.1%) or biomass fuel (52.4%). Thus overall proportion of PH among reported cases of COPD patients was 48.6% in our study. Conclusion: With the increase in severity of COPD the proportion of PH rises. This study emphasizes the early detection of COPD and the importance of screening for PH through clinical assessment and non- invasive techniques 2-D Echocardiography.

scholarly journals A cross sectional study of clinical profile and evaluation of pulmonary hypertension in Chronic Obstructive Pulmonary Disease patients in a tertiary care hospital of Mangalore, India

2019 ◽  
Vol 6 (2) ◽  
pp. 330
Author(s):  
Kshama S. Ramesh ◽  
Devdas B. Rai ◽  
Shayma Sheikh Abdulla ◽  
Jyothsna B. K.
Keyword(s):  
Pulmonary Hypertension ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Cardiac Complications ◽  
Chronic Obstructive ◽  
Close Monitoring ◽  
Care Hospital ◽  
Cross Sectional ◽  
Copd Patients ◽  
Significant Difference

Background: The objectives was to study the clinical profile of COPD patients and to evaluate pulmonary hypertension in COPD patients by non-invasive methods.Methods: A prospective observational study of patients who satisfy all inclusion and exclusion criteria in OPD or admitted in medical wards of AJIMS Mangalore. The study was conducted from October 2017 to October 2018 with the sample size of 90 subjectsResults: Out of 90 subjects 53 (58.8%) of them had pulmonary hypertension. Among the subjects who had pulmonary hypertension 29 (54.72%) of them had moderate pulmonary hypertension, 17 (32.08%) of them had severe pulmonary hypertension and 7 (13.20%) of them had mild pulmonary hypertension. Mean age among the subjects who had pulmonary hypertension was 64.24+7.62yrs and mean age among the subjects who didn’t had pulmonary hypertension was 51.87+8.97yrs. There was a statistically significant difference found between mean age and pulmonary hypertension. Mean duration of diseases among the subjects who had pulmonary hypertension was 8.13+1.74yrs and Mean duration of diseases among the subjects who didn’t had pulmonary hypertension was 5.36+1.98yrs. There was a statistically significant difference found between mean duration of disease and pulmonary hypertension.Conclusions: Due to high prevalence of pulmonary hypertension we suggest screening for the all COPD patients for cardiac complications. This will help in identifying the individual who requires close monitoring and also in reducing the mortality.

scholarly journals Osteoporosis in Chronic obstructive Pulmonary Disease (COPD) Patients

2018 ◽  
Vol 19 (2) ◽  
pp. 114-118
Author(s):  
Md Khairul Islam ◽  
Fahima Sharmin Hossain ◽  
Mostofa Kamal Chowdhury ◽  
Prodip Kumar Biswas
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Complete Blood Count ◽  
Demographic Data ◽  
Smoking History ◽  
Chronic Obstructive ◽  
Mineral Density ◽  
Obstructive Pulmonary Disease ◽  
X Ray ◽  
Copd Patients

Background: Osteoporosis is one of the most common systemic features of Chronic obstructive pulmonary disease (COPD). But there had been no data regarding osteoporosis in COPD patients in Bangladesh. Objectives: To determine the frequency of osteoporosis in COPD patients.Materials & Methods: This was a cross sectional observational study. COPD patients were recruited from Sarkari kormachari hospital. Patients were excluded if they had asthma, any disease affecting bones and calcium homeostasis or were receiving drugs related to bone metabolism. Demographic data were collected including age, smoking history, inhaled corticosteroid use, body mass index, treatment history hospital admission. Chest x-ray was done to exclude any infection or malignancy. Blood was obtained for complete blood count, renal function test, CRP. Bone mineral density (BMD; g/cm2) was conducted by using dual energy x-ray absorptiometry scan (DXA scan) at second to fourth lumbar spines (L2-4) and femoral neck.Results: The overall prevalence of osteoporosis according to the lowest T-score at either L2-4 or femoral neck were 56.7%. This is very high than other country. BMI and CRP were significantly associated with osteoporosis.Conclusion: The frequency of osteoporosis in Bangladeshi COPD patients was higher than others. Osteoporosis was associated with low BMI and high level of CRP.J MEDICINE JUL 2018; 19 (2) : 114-118

Study on Utilization Pattern of Pulmonary Inhalers in Inpatient at Tertiary Care Teaching Hospital, Coimbatore, India

2021 ◽  
Vol 15 (5) ◽  
pp. 1285-1288
Author(s):  
Askari Mirzaei ◽  
Chitra Bhojan
Keyword(s):  
Teaching Hospital ◽  
Tertiary Care ◽  
Pharmacist Intervention ◽  
Inhalation Technique ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Copd Patients ◽  
12 Steps

Objective: Aim of the study was to assess medication adherence to understand various determinants of medication non-adherence in inpatients at a tertiary care hospital, Coimbatore, India. Methodology: It is a prospective observational study conducted in the inpatient department at a Tertiary Care Teaching Hospital. Asthma or COPD patients were randomly recruited over six months from the ward's clinics. The inhalation technique was assed utilizing the questionnaires there were 11 steps for MDI and 12 steps for MDI + spacer each correct technique conveyed a score of 1 and the wrong technic conveyed 0. The adherence to the inhaler technique was assessed utilizing the recipe correct dose/incorrect dose*100 and the purposes behind nonadherence were additionally noted. Result: In our study out of 120 patients 53.3% were diagnosed with COPD and 46.7% were asthmatic, and 10.8% asthmatics and 20% COPD patients were endorsed with budesonide MDI. About 10% of asthmatics and 9.1 COPD patients have endorsed with budesonide MDI+ spacer. About 4.1% asthmatics and 2.5% COPD patients were endorsed with salbutamol MDI. About 17% asthmatics and 10% COPD patients were endorsed with MDI ipratropium and 8% asthmatics and 12.5% COPD patients were recommended with ipratropium MDI+ spacer. At the point when the knowledge concerning the use of inhalers was surveyed utilizing standard questionnaire, which had 11 steps for MDI and 12 steps for MDI+ spacer every questionnaire had scoring of 0 addressing not playing out the progression, 1 addressing following the progression the scores were high after pharmacist intervention when contrasted with before pharmacist intervention Conclusion: The current outcomes feature the requirement for pharmacist interventions pointed toward improving adherence to inhalers in COPD and asthmatic patients. Keywords: adherence, chronic obstructive pulmonary disease, Inhalers, Asthma

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