scholarly journals Degree of Pulmonary Hypertension in Patients of COPD Attending a Tertiary Care Hospital

2021 ◽  
Vol 6 (05) ◽  
pp. 312-315
Author(s):  
Afshan Ali Shaik ◽  
Durga Lawande
Keyword(s):  
Pulmonary Hypertension ◽  
Tertiary Care ◽  
Systolic Pressure ◽  
Biomass Fuel ◽  
Pulmonary Artery Systolic Pressure ◽  
Chronic Obstructive ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Copd Patients ◽  
Increased Risk

Introduction: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality in India. The development of pulmonary hypertension (PH) in COPD adversely affects survival and exercise capacity and is associated with an increased risk of severe acute exacerbation. Aims and Objectives: Present study aimed to describe the distribution of echocardiographically assessed pulmonary artery systolic pressure in the COPD patients attending pulmonary medicine OPD, to estimate the proportion of PH among such patients and to identify associated factors. Methodology: This Cross sectional study was done on 145 patients of COPD fulfilling the inclusion criteria were included in this study. These patients were evaluated for the presence of PH using chest X-ray, 2D-Echocrdiography and electrocardiogram. Results: Pulmonary hypertension was present in 17 (29.8%) patients with moderate, 36 (60%) with severe and 18 (72%) with very severe COPD. Mild PH was seen in 52(73%), moderate in 11(15.4%) and severe in 8(11.2%) patients. Patient exposed to both smoking and biomass fuel smoke had more frequent occurrence of PH (56.8%) as compared to exposure to single risk factor of either tobacco smoke (47.1%) or biomass fuel (52.4%). Thus overall proportion of PH among reported cases of COPD patients was 48.6% in our study. Conclusion: With the increase in severity of COPD the proportion of PH rises. This study emphasizes the early detection of COPD and the importance of screening for PH through clinical assessment and non- invasive techniques 2-D Echocardiography.

scholarly journals A cross sectional study of clinical profile and evaluation of pulmonary hypertension in Chronic Obstructive Pulmonary Disease patients in a tertiary care hospital of Mangalore, India

2019 ◽  
Vol 6 (2) ◽  
pp. 330
Author(s):  
Kshama S. Ramesh ◽  
Devdas B. Rai ◽  
Shayma Sheikh Abdulla ◽  
Jyothsna B. K.
Keyword(s):  
Pulmonary Hypertension ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Cardiac Complications ◽  
Chronic Obstructive ◽  
Close Monitoring ◽  
Care Hospital ◽  
Cross Sectional ◽  
Copd Patients ◽  
Significant Difference

Background: The objectives was to study the clinical profile of COPD patients and to evaluate pulmonary hypertension in COPD patients by non-invasive methods.Methods: A prospective observational study of patients who satisfy all inclusion and exclusion criteria in OPD or admitted in medical wards of AJIMS Mangalore. The study was conducted from October 2017 to October 2018 with the sample size of 90 subjectsResults: Out of 90 subjects 53 (58.8%) of them had pulmonary hypertension. Among the subjects who had pulmonary hypertension 29 (54.72%) of them had moderate pulmonary hypertension, 17 (32.08%) of them had severe pulmonary hypertension and 7 (13.20%) of them had mild pulmonary hypertension. Mean age among the subjects who had pulmonary hypertension was 64.24+7.62yrs and mean age among the subjects who didn’t had pulmonary hypertension was 51.87+8.97yrs. There was a statistically significant difference found between mean age and pulmonary hypertension. Mean duration of diseases among the subjects who had pulmonary hypertension was 8.13+1.74yrs and Mean duration of diseases among the subjects who didn’t had pulmonary hypertension was 5.36+1.98yrs. There was a statistically significant difference found between mean duration of disease and pulmonary hypertension.Conclusions: Due to high prevalence of pulmonary hypertension we suggest screening for the all COPD patients for cardiac complications. This will help in identifying the individual who requires close monitoring and also in reducing the mortality.

scholarly journals Assessment of Prescription Pattern Among COPD Patients in Departments of General Medicine Ward and Pulmonology in Tertiary Care Hospitals of Khammam Region

2020 ◽  
Vol 11 (2) ◽  
pp. 1798-1806
Author(s):  
Sai Lakshmi Srikala T ◽  
Saika V ◽  
Raveendra Babu K ◽  
Chinna Eswaraiah M
Keyword(s):  
Tertiary Care ◽  
General Medicine ◽  
Symptomatic Treatment ◽  
Chronic Obstructive ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Copd Patients ◽  
Co Morbidity ◽  
Study Population

Chronic obstructive pulmonary disease is a common preventable and treatable disease. It has been a leading cause of morbidity and mortality in industrialized and developing countries. Drug utilization research promotes the rational use of drugs and decreases adverse drug reactions in the population. The present study is aimed to analyze and evaluate the trends and patterns of prescribing drugs among COPD patients. A prospective observational study was conducted in 301 patients admitted in the general and pulmonary medicine departments over six months at a tertiary care hospital in Khammam region. Out of the 301 study population, male patients were more (81.39%).  The majority of the patients were from the age group of 51-60 years (30.56%). Smoking was found to be more prominent in the study population (63.6%). Bronchodilators (46.90%) were mostly prescribed class of drugs in the management of COPD followed by Systemic Corticosteroids (20.60%), Antibiotics (19.09%) Most common co-morbidity was found to be Hypertension (19.85%). The study concludes that symptomatic treatment was given to COPD patients in the hospital. The prescribing pattern was found to be in concordance with the current GOLD guidelines in the management of COPD patients

scholarly journals Assessment of nutritional status in chronic obstructive airways disease patients in a tertiary care hospital at Himachal Pradesh, India: a cross sectional study

2019 ◽  
Vol 6 (8) ◽  
pp. 3543
Author(s):  
Balbir Singh ◽  
Pramod Shridhar ◽  
Kamaljit Singh ◽  
Rajesh Garg ◽  
Herleen Pabla ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Copd Patients

Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortatlity worldwide. Malnourishment in COPD patients is very common and is a prognostic factor in its treatment. The present study has been conducted to assess nutritional status in COPD patients and its correlation with severity of disease.Methods: This institutional based analytical cross sectional study was conducted in the Department of Pulmonary Medicine at tertiary care hospital in Himachal Pradesh (India) from 1 Dec 2017 to 31st May 2018. A total of 52 COPD participants attending the pulmonary Medicine OPD and fulfilling the inclusion criteria were enrolled.Results: All participants reported being smoker since long with the mean years of smoking since 31 years and about 13.6 cigarettes being smoked per day. 22 (42%) of the participants were undernourished as per BMI criteria But when  compared with MUAC criteria, a large number 38 (73%) came out to be undernourished. haemoglobin and cholesterol levels were less in patients with severe diseases than mild and moderate category (76.9%).Conclusions: The malnourishment and severity of the disease has direct correlation. More the severity of COPD, more is the malnourishment. Biochemical parameters, although not deranged significantly in any group, but more on the lower side in patients with severe COPD. There is a need for regular nutritional assessment of every COPD patient and recommendation of supplementary food for them.

A Correlational study on quality of life and disease severity among Chronic Obstructive Pulmonary Disease (COPD) clients attending a pulmonary Medicine OPD of a Tertiary care hospital, Kolkata

2021 ◽  
pp. 528-532
Author(s):  
Uma Rani Adhikari ◽  
Soma Roy
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Disease Severity ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is recently the most common chronic lung disease and presents a serious medical, economic, and social problem for people. A correlational survey research was adopted to identify relationship between quality of life and disease severity among Chronic Obstructive Pulmonary Disease (COPD) clients attending Pulmonary Medicine OPD in a selected hospital, Kolkata with the objectives to assess the quality of life of Chronic Obstructive Pulmonary Disease (COPD) clients and to find out correlation between disease severity and quality of life among Chronic Obstructive Pulmonary Disease (COPD) clients. Purposive sampling technique was adapted to select 138 Chronic Obstructive Pulmonary Disease (COPD) clients attending Pulmonary Medicine OPD in a tertiary care hospital, Kolkata. The structured interview schedule was used to collect on demographic data and standardized WHO QOL BREF tool was used to assess Quality of Life. Standardized GOLD criteria were used to assess disease severity of COPD clients. Reliability of the demographic data collection tool was established by inter- rater method and r was 0.77. All the tools were tried out before final data collection. The finding of the study revealed statistically non-significant relationship between all the domain of QOL and disease severity of COPD patients. Total Quality of Life score is also not significantly related with COPD Disease severity score. The study results also showed that QOL is not associated with sociodemographic characteristics. The study concluded that, there is no correlation between quality of life and disease severity.

scholarly journals Assessment of Disease Knowledge, Medication Adherence, HRQOL in COPD Patients at a South Indian Tertiary Care Hospital

2021 ◽  
Vol 11 (5) ◽  
pp. 57-60
Author(s):  
S. Padmakar ◽  
R.B. Purandhar Chakravarthy ◽  
Prodduturu Sai Karthik ◽  
B.U. Charitha ◽  
T. Harini ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Obstructive Pulmonary Disease ◽  
Disease Knowledge ◽  
Adherence To Medication ◽  
South Indian ◽  
Copd Patients ◽  
Ethical Committee Approval

Introduction: Chronic obstructive pulmonary disease (COPD) is a progressive, life-threatening disease of the lungs, gradually causes breathlessness and predisposes to exacerbations and serious illness. The main objectives of the study are to evaluate disease knowledge, medication adherence, and health-related quality of life among COPD patients. Methodology: A Hospital-based, single-entered prospective observational study was conducted at a government general hospital, Andhra Pradesh. India after ethical committee approval. This study was conducted for 6 months with a sample size of 80 patients. Results: According to our study, the majority of the patients 36 (45%) don’t have disease knowledge, where a few numbers of patients 7 (8.75%) is having disease knowledge as per BCKQ score values. 11.25% of patients have the lowest MMAS scores whereas 58.75% were found to have higher MMAS scores and 37.5% of total patients have higher CAT scores, and 12.5% of patients have lower CAT scores. Conclusion: We found that majority of the patients have poor disease knowledge, lower adherence to medication regimens, and substandard HRQOL. Keywords: COPD knowledge, medication adherence, and HRQOL.

Effects of Sildenafil on spirometric pulmonary function parameters, pulmonary artery systolic pressure and BNP levels in patients with chronic obstructive pulmonary disease and erectile dysfunction

2021 ◽  
Vol 6 (4) ◽  
pp. 226-233
Author(s):  
Keski Hakan ◽  
Demirtunç Refik
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Erectile Dysfunction ◽  
Single Dose ◽  
Pulmonary Artery ◽  
Systolic Pressure ◽  
Pulmonary Artery Systolic Pressure ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Baseline Values

We aimed to investigate the effects of Sildenafil on pulmonary artery systolic pressure (PASP) as well as forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) and serum brain-type natriuretic peptide (BNP) levels in stable chronic obstructive pulmonary disease (COPD) patients with erectile dysfunction (ED). This was a prospective non-controlled interventional study that recruited COPD patients with ED between the ages of 49 and 79. International Index of Erectile Dysfunction Form (IIEF-5) was used for the evaluation of ED. Patients who had pulmonary artery systolic pressure >50 mmHg were included in the study. Single-dose Sildenafil 100 mg was administered orally to the patients. Before and after the drug ingestion, spirometry and echocardiographic measurements were performed, and serum BNP levels were measured as well. Forty-five male COPD patients with ED were included. Both percent predicted, and absolute FEV1 values increased significantly after the Sildenafil administration compared with baseline values (p<0.01). Similarly, the FEV1/FVC ratio also increased significantly with the Sildenafil administration compared to baseline values (p<0.01). Pulmonary artery systolic pressure significantly decreased from its baseline value with Sildenafil administration (p<0.01). Serum BNP values significantly reduced with Sildenafil administration compared to the pre-treatment values (p<0.01). This is the first study conducted in COPD patients with erectile dysfunction who had also pulmonary hypertension. The single-dose Sildenafil administration reduced PASP and serum BNP levels significantly. For the first time in the literature, we showed that the spirometric pulmonary function tests, namely FEV1 and FEV1/FVC ratio, improved significantly with the Sildenafil administration.

scholarly journals Prevalence of Pulmonary Hypertension in an Unselected Community-Based Population: A Retrospective Echocardiographic Study—RES-PH Study

2021 ◽  
Vol 11 (6) ◽  
pp. 489
Author(s):  
Egidio Imbalzano ◽  
Marco Vatrano ◽  
Alberto Lo Gullo ◽  
Luana Orlando ◽  
Alberto Mazza ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Systolic Dysfunction ◽  
Systolic Pressure ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Pulmonary Artery Systolic Pressure ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Equal Distribution ◽  
Ventricular Ejection Fraction

Introduction. The actual prevalence of pulmonary hypertension (PH) in Italy is unknown. Echocardiography is useful in the screening of patients with suspected PH by estimation of the pulmonary artery systolic pressure (PASP) from the regurgitant tricuspid flow velocity evaluation, according to the simplified Bernoulli equation. Objectives. We aimed to evaluate the frequency of suspected PH among unselected patients. Methods. We conducted a retrospective cross-sectional database search of 7005 patients, who underwent echocardiography, to estimate the prevalence of PH, between January 2013 and December 2014. Medical and echocardiographic data were collected from a stratified etiological group of PH, using criteria of the European Society of Cardiology classifications. Results. The mean age of the study population was 57.1 ± 20.5 years, of which 55.3% were male. The prevalence of intermediate probability of PH was 8.6%, with nearly equal distribution between men and women (51.3 vs. 48.7%; p = 0.873). The prevalence of high probability of PH was 4.3%, with slightly but not significant higher prevalence in female patients (43.2 vs. 56.8%; p = 0.671). PH is predominant in patients with chronic obstructive pulmonary disease (COPD) or left ventricle (LV) systolic dysfunction and related with age. PASP was significantly linked with left atrial increase and left ventricular ejection fraction. In addition, an increased PASP was related to an enlargement of the right heart chamber. Conclusions. PH has a frequency of 4.3% in our unselected population, but the prevalence may be more relevant in specific subgroups. A larger epidemiological registry could be an adequate strategy to increase quality control and identify weak points in the evaluation and treatment of these patients.

scholarly journals Aspergillus spp. infection as a cause of acute exacerbations of chronic obstructive pulmonary disease: a prospective observational study

2019 ◽  
Vol 7 (5) ◽  
pp. 1604
Author(s):  
Lashmipriya S. ◽  
Ravindran Chetambath ◽  
Amitha Sunny ◽  
Sanjeev Shivashankaran ◽  
Muhammed Aslam
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Obstructive Pulmonary Disease ◽  
Aspergillus Infection ◽  
Acute Exacerbations

Background: Majority of exacerbations of COPD (AECOPD) are due to infections. Usual agents causing AECOPD are gram negative bacteria, but rarely viruses and fungi are also implicated. However, the role of fungal infection, especially Aspergillus spp. in the clinical deterioration of COPD still remains unclear. This prospective observational study looks at the prevalence of aspergillus infection in AECOPD. The Objectives of this study were to analyse the prevalence and risk factors associated with Aspergillus infection in AECOPD, and to investigate the clinical outcomes.Methods: Patients admitted with AECOPD for a period of 3 months from 1st October 2017 to 31st December 2017 were prospectively included from ICU and general ward of Pulmonary Medicine department of a tertiary care hospital. Clinical, radiological and microbiological data were collected at admission and during the hospital stay. Clinical course and outcome are recorded.Results: There were 104 cases of AECOPD during the study period out of which 96 were males and 8 were females. 17 patients had evidence of aspergillus infection and diabetes was found to be an independent risk factor for aspergillus infection.Conclusions: Aspergillus infection is an important cause of COPD exacerbation and this is directly related to diabetes mellitus.

scholarly journals A Predictive Model for Dilated Cardiomyopathy With Pulmonary Hypertension

2021 ◽  
Author(s):  
Jiahua Liang ◽  
Ruochen Zhu ◽  
Yi Yang ◽  
Rong Li ◽  
Chuangxiong Hong ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Dilated Cardiomyopathy ◽  
Predictive Model ◽  
External Validation ◽  
Systolic Pressure ◽  
Vital Signs ◽  
Left Ventricular ◽  
Pulmonary Artery Systolic Pressure ◽  
Chronic Obstructive ◽  
The Impact

Abstract Background: Dilated cardiomyopathy (DCM) is defined as a serious cardiac disorder caused by the presence of left ventricular dilatation and contractile dysfunction in the absence of severe coronary artery disease and abnormal loading conditions. The incidence of cardiac death is markedly higher in patients with DCM with pulmonary hypertension (PH) than in DCM patients without PH. However, no previous studies have constructed a predictive model to predict PH in patients with DCM.Methods: Data from 218 DCM patients were collected. The diagnostic criterion for PH by echocardiography was a pulmonary artery systolic pressure (PASP) ≥ 40 mmHg. Basic information, vital signs, comorbidities and biochemical data of each patient were determined. The impact of each parameter on PH was analysed by univariable and multivariable analyses, the data from which were employed to establish a predictive model. Finally, the discriminability, calibration ability, and clinical efficacy of the model were verified for both the modelling group and the external validation group.Results: We successfully applied a history of chronic obstructive pulmonary disease (COPD) or chronic bronchitis, systolic murmur (SM) at the tricuspid area, SM at the apex and brain natriuretic peptide (BNP) level to establish a model for predicting PH in DCM. The model was proven to have high accuracy and good discriminability, calibration ability, and clinical application value.Conclusions: A model for predicting PH in patients with DCM was successfully established. The new model is reliable for predicting DCM with PH and has good clinical applicability.

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