scholarly journals Progressive Disseminated Superficial Actinic Porokeratosis: a Case Report with a Family History in Three Generations

2013 ◽  
Vol 5 (3) ◽  
pp. 131-140
Author(s):  
Milica Stepanović ◽  
Mirjana Paravina ◽  
Danica Janjić Spasić

Abstract Disseminated superficial actinic porokeratosis is the most common form of porokeratosis in adults, which develops in the third or fourth decade of life, but may also occur later or earlier, more frequently in females, particularly in countries with high sun exposure. Lesions are numerous, uniform, superficial with central atrophy, demarcated by a distinct peripheral ridge, and usually found on sun exposed areas or elsewhere. The disease is inherited as an autosomal dominant condition. We present a 57-year-old retired woman. Her initial skin changes, affecting the face, developed in her thirties, and they have not changed their features since. In the following years, changes developed on the extensor surface of her arms and legs, with more prominent erythema, and then also on other parts of the body, including palms and soles, presenting as dark brown pigmented patches. Her mother had similar changes, and her daughter, who lives abroad, also has them. On examination, the patient presented with facial lesions, patches 2-3 mm wide, with peripheral hyperpigmentation and a pale center. There were multiple, 2-3 mm wide, dark brown lesions on the extremities and trunk. The lesions were either flat or with atrophic center with darker filiform corneal rim. Pathohistolgical examination revealed a "cornoid lamella", which is pathognomonic for the diagnosis of porokeratosis. Auxiliary diagnostic methods were also used - dermoscopy and Gentian violet staining. The patient was advised to avoid sun exposure and to apply photoprotective sunscreens. In conclusion, this is a case report of a disseminated superficial actinic porokeratosis that affected three generations of a family. Our patient developed lesions on palms and soles as well. A review of available world literature shows that this is the second case report of disseminated superficial actinic porokeratosis with palmoplantar involvement.

2020 ◽  
Vol 16 (3) ◽  
pp. 320-324
Author(s):  
Lesya Besh ◽  
◽  
Oksana Matsyura ◽  
Olesya Besh ◽  
Olga Troyanovska ◽  
...  

Eczema herpeticum is a chronic dermatosis with erosive and ulcerative lesions of the skin in children of a predominantly young age. The clinical case presented in this article shows the severe course of herpesvirus infection combined with atopic dermatitis in a 5-month infant. A rash in the form of vesicles and pustules throughout the body with a predominant localisation on the skin of the face, the scalp, neck, and chest was found in the course of the examination of the child. Influence of infections on the course of allergic processes is an ambiguous and complicated issue. It has been proved that an infection can contribute to the development of allergies and exacerbate the course of already existing allergic inflammation. In recent years, an increasing number of studies have shown the preventive effect of infection on the development of allergic pathology in children, especially during the first years of life.


2017 ◽  
Vol 22 (2) ◽  
pp. 229-231 ◽  
Author(s):  
Bahman Sotoodian ◽  
Muhammad N. Mahmood ◽  
Thomas G. Salopek

Introduction: Porokeratosis is a benign hyperkeratotic skin tumour due to a clonal proliferation of keratinocytes and is characterised by a telltale annular threadlike configuration along the border of a skin-colored to erythematous papule that can expand centrifugally. Case Presentation: We are presenting a clinical and dermoscopic case of pigmented disseminated superficial actinic porokeratosis (DSAP) limited to the upper trunk of a white man with sun-damaged skin. Literature Review and Conclusion: A thorough review of PubMed failed to identify any previous reports on the dermoscopic appearance of pigmented porokeratosis. On dermoscopy, the presence of black dots limited to the periphery of the lesions is due to pigment incontinence and melanophages within the superficial papillary dermis limited to the area below the cornoid lamella. Pigmented DSAP is a unique morphological presentation of porokeratosis, and it is essential to be familiar with its clinical and dermoscopic presentation.


Author(s):  
Lilia Andreevna Garanina ◽  
Inna Vitalievna lyalina

The combination of speech therapy and dentistry is increasingly becoming a necessary tandem in identifying anomalies of the dentoalveolar system in the early stages of development of the speech apparatus. It is very important to pay attention to risk factors during pregnancy, because it is during the period of intrauterine development of the fetus that deviations from the normal structure of the body occur, leading to various anomalies. This is due to many factors. The main ones include the ecological situation, social status, quality of food and water, as well as the working conditions of a pregnant woman. According to statistics, the number of detected congenital maxillofacial anomalies has doubled over the past 40 years. According to the WHO, the frequency of such cases is 1.6 per 1000 newborns, ranking second after heart defects. Sometimes parents do not pay enough attention to such important aspects as the location of the tongue in the oral cavity, the degree of tension and involvement of the muscles of the face and neck, the length of the frenum in the child’s oral cavity, which directly affects the sound production, speech production, facial symmetry and aesthetics of a smile. This article presents the main methods of speech therapy in working with patients with dental anomalies, as well as additional diagnostic methods to identify concomitant pathologies. Due to the timely detection of various anomalies, a dentist surgeon, using the extensive capabilities of modern dentistry, is able to significantly improve the quality of life of a child. This is one of the provisions for the prevention of serious complications regarding the dentition, which can affect the general development and health of the child.


Biofeedback ◽  
2012 ◽  
Vol 40 (2) ◽  
pp. 57-61 ◽  
Author(s):  
Jeffrey E. Bolek

The treatment of muscle dysfunction in the muscles around the face is particularly challenging. In addition to being the most observable muscles in the body, the limited area with which to work, the high firing rate, and the increased risk of picking up crosstalk from muscles in close proximity all add to the challenge. This case report describes the treatment of a young child with seventh cranial nerve palsy of the face.


2017 ◽  
Vol 107 (2) ◽  
pp. 158-161
Author(s):  
Sanaz Lalehparvar ◽  
Ayesha Mohiuddin ◽  
Irene Labib

Cutaneous horns (cornu cutaneum) are chronic, dense, hyperkeratotic cutaneous lesions resembling the horn of an animal. These lesions are associated with a variety of benign, premalignant, and malignant cutaneous diseases. Cutaneous horns are often found on the upper parts of the body, such as the face, neck, and shoulders. These lesions rarely occur in areas with no sun exposure, such as the feet. We present the case of a 51-year-old man with two cutaneous horns on the lateral aspect of the third digit of the left foot. Treatment consisted of excision of the lesions and application of a full-thickness skin graft from the ipsilateral sinus tarsi.


Author(s):  
Małgorzata Braczkowska ◽  
Lidia Glinka ◽  
Marcin Mieszkowski ◽  
Bułat Tuyakov ◽  
Aleksandra Gutysz-Wojnicka

Introduction: Septic shock is defined as a life-threatening organ failure caused by an abnormal response of the body to infection. Urinary tract infections (UTIs) constitute about 10%–20% of all community-acquired infections and about 40%–50% of hospital-acquired infections. In patients with impaired immunity they may lead to sepsis. Strains of Klebsiella pneumoniae are often multidrug resistant, and therapeutic chances are limited where they occur. Aim: The aim of this paper is to discuss the most recent guidelines in diagnosing and treating sepsis, referring to a clinical case report. Case study: The study presents a case of septic shock in a 44-year-old female patient in a community-acquired UTI caused by K. pneumoniae extended-spectrum β-lactamases (ESBL+). Results and discussion: The course of septic shock proved fatal. As the stay in the intensive care unit (ICU) was short, this precluded implementing full diagnostic procedures and identifying the source of infection. A post mortem examination was performed to establish the cause of death and aetiology of the infection. Conclusions: K. pneumoniae ESBL+ has become a growing epidemiological problem in Poland and all over the world. This pathogen increasingly often leads to community-acquired infections and its multidrug resistance makes the applied therapies ineffective. Diabetes, one of the modern lifestyle diseases, impairs resistance and accelerates rapidly progressing septic shock with multiple organ failure. Late diagnosis of sepsis, because of considerable metabolic and cellular changes, brings about tragic results. Despite implementing new diagnostic methods and therapies, the mortality rate in sepsis still remains very high.


2010 ◽  
Vol 1 (2) ◽  
pp. 125-127
Author(s):  
Vikram Kulkarni ◽  
Vidisha Athanikar ◽  
Trupti Katti

Abstract Objective To report a rare case of angioleiomyoma with regard to size, type (variant) and location. Case report 45 years old male presented with painless swelling on the right side of the face since 2 years. On examination, the swelling was 4 cm × 3 cm in size, firm in consistency with well-defined margins. It was not adhering to overlying skin and underlying structures. The swelling was excised and sent for histopathological diagnosis. It was reported as solid variant of angioleiomyoma based on microscopic features. Conclusion According to the world literature, large angioleiomyoma on face is rare or not reported yet (usually less than 2 cm) and location (usually externar ear, tip of nose, lip). This case is presented for its uniqueness in size —large (4 cm x 3 cm); painlessness; variant; and location.


2021 ◽  
Vol 12 (1) ◽  
pp. 69-71
Author(s):  
Mancy Abdullah

Disseminated superficial actinic porokeratosis (DSAP) is the most common type of porokeratosis, occurring mainly on sun-exposed skin. Chronic sun exposure is one of the main risk factors, in addition to genetic susceptibility. Most published data concerning the relationship between vitiligo and its predisposition to nonmelanoma skin cancer suggests that patients with vitiligo show the same or even a lower incidence than other populations. Herein, we report a case of disseminated superficial actinic porokeratosis occurring in vitiligo in which chronic sun exposure was the main risk factor


2021 ◽  
Vol 20 (2) ◽  
pp. 94-99
Author(s):  
Sura Qais Mahmood Almaroof ◽  
◽  
Issam Tariq Abdul Wahaab

Background: Steven Johnson syndrome (SJS) is a rare disease that is characterized by acute cutaneous manifestation represented by eruptions of the skin and the mucosal membranes. SJS is an immune-mediated disease, a hypersensitive reaction, characterized by hyperpigmentation of the mucous membranes, rash on the skin and multiple bullae and erosions scattered all over the body especially the face, trunk, and the extremities. Many studies reported that the incidence rate of the SJS was about 1.2 – 6 cases/ million each year and it is more common among males while the toxic epidermal necrolysis (TEN) is more common among females. In addition to the cutaneous manifestations.SJS might show multiple systemic manifestations including the liver, lungs and kidneys. In this case we reported the development of Steven Johnson syndrome in relation to the use of lamotrigine antiepileptic drug.


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