scholarly journals NYERI PERUT BERULANG SAAT HAID, BERISIKO MANDUL?

2019 ◽  
Vol 19 (2) ◽  
Author(s):  
Mohd Andalas ◽  
Cut Rika Maharani ◽  
Rayhan Shafithri
Keyword(s):  
Abdominal Pain ◽  
Medical Therapy ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Daily Activities ◽  
Women Of Reproductive Age ◽  
Operative Laparoscopy ◽  
Infertile Women ◽  
Stomach Pain ◽  
Tissue Damages

Abstract. Stomach pain (dysmenorrhea) is abdominal cramps and pain during the menstrual period which can interfere with the daily activities of women of reproductive age. Dysmenorrhea is one of the symptoms that needs to be considered because it is often experienced by women and is an early sign of suffering from endometriosis. The presence of abdominal pain in women during menstruation, accompanied by pelvic pain, and infertility is a classic trias of symptoms used to diagnose endometriosis. Endometriosis occurs in almost 10% of women in the reproductive age period and more than 25-40% in infertile women. The risk of infertility is also linked because inflamed endometriosis tissue damages sperm and egg cells. Some treatments that can be done for patients with endometriosis are medical and surgical therapy. If medical therapy fails, operative laparoscopy can be alternative and hysterectomy can be considered for patients who no longer expect their reproductive function. Keywords: abdominal pain, endometriosis, infertility, dysmenorrhea. Abstrak. Nyeri Perut (dismenore) merupakan kram perut dan nyeri selama periode menstruasi yang dapat mengganggu aktivitas sehari-hari wanita usia reproduksi. Dismenore merupakan  salah satu gejala yang perlu dipertimbangkan karena kerap dialami wanita dan menjadi tanda awal  menderita endometriosis. Adanya nyeri perut pada wanita saat haid, disertai  nyeri panggul, dan infertilitas merupakan trias klasik gejala yang digunakan untuk mendiagnosis endometriosis. Endometriosis terjadi pada hampir 10% wanita dalam kurun  usia reproduksi dan lebih dari 25-40% pada wanita infertil (mandul). Risiko mandul juga dikaitkan karena jaringan endometriosis yang meradang merusak  sperma dan sel telur. Beberapa pengobatan yang dapat dilakukan pada penderita endometriosis adalah terapi medikamentosa dan pembedahan. Jika terapi medikamentosa gagal, laparoskopi operatif dapat menjadi altenatif dan histerektomi dapat dipertimbangkan pada pasien yang tidak mengharapkan fungsi reproduksi lagi. Kata Kunci: nyeri perut, endometriosis, infertilitas, dismenore.

scholarly journals Features of reproductive function in infertile women with hyperthyroidism

2021 ◽  
Vol 38 (1) ◽  
pp. 64-71
Author(s):  
L. M. Rzakulieva ◽  
A. E. Hajizade
Keyword(s):  
Thyroid Gland ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Control Group ◽  
Women Of Reproductive Age ◽  
Early Menopause ◽  
Ovarian Volume ◽  
Infertile Women ◽  
Group I ◽  
Toxic Goiter

Objective. The aim was to study the characteristics of reproductive function in women of fertile age with infertility and hyperfunction of the thyroid gland. Materials and methods. The object of the study was 148 women of fertile age. To compare the indicators obtained by special methods, the control group included the indicators of laboratory and instrumental examination of 30 non-pregnant women of reproductive age. Reproductive function was evaluated in 118 women with hyperthyroidism: 58 retrospectively (group I) and 60 prospectively (group II); the control group consisted of 30 healthy women of reproductive age. Hormonal studies were performed by radioimmune and enzyme immunoassay methods using the automatic analyzer "Cobb" ("Hoffmann La Roche", Switzerland), as well as DPS test systems the analyzer Immulite (USA). Ultrasound of the thyroid gland was performed by a linear sensor with a frequency of 7.5 MHz. The volume of the thyroid gland was calculated according to the Bruno formula. Results. For women of fertile age with hyperthyroidism, a decrease in ovarian reserve is characteristic that is manifested by a significant increase in FSH level (14.1 3.1 IU / L, p 0.05), and a decrease in inhibin B level (35.9 12,7 pg / ml, p 0.05). In 47.7 % of women of fertile age with hyperthyroidism, there is a decrease in ovarian volume and a significant reduction in the average number of antral follicles of normal size (4.34 1.56, p 0.05). Conclusions. Based on the results obtained, it can be assumed that in diffuse toxic goiter there are not only functional disorders (metabolism of hormones of the reproductive system), but also deep organic changes in the structure of the ovaries that leads to a rapid suppression of their functions. In cases of thyroid diseases, the clinical manifestation of these changes is premature and early menopause.

Implantation capacity of endometry of veteran women, with contusion in anamnesis, with unrealized reproductive function

2020 ◽  
pp. 44-49
Author(s):  
V.V. Kaminskiy ◽  
◽  
L.V. Suslikova ◽  
A.V. Serbeniuk ◽  
◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Reproductive Health ◽  
Military Service ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Operative Laparoscopy ◽  
Post Concussion Syndrome ◽  
Civilian Women

The objective: improving the efficiency of diagnosis and treatment of pathology and implantation ability of the endometrium in women of reproductive age who took part in hostilities and received concussions. Materials and methods. The study of endometrial pinopodia was carried out in 35 women of reproductive age who took part in hostilities and received concussions, who on the 21st day of the MC underwent operative laparoscopy and hysteroscopy with endometrial sampling for histological examination and scanning electron microscopy. Of these women, 22 patients – a comparison group – of reproductive age with a history of trauma without post-concussion syndrome and 13 in the main group, women of reproductive age, have the consequences of contusion in the form of post-concussion syndrome. Served as control 10 samples of endometrium from civilian women of reproductive age. The average age of the surveyed was 27.08±4.23 years. The period of stay in the combat zone was 29.34±9.21 months, the time from the moment of receiving a slight traumatic brain injury (contusion) was 18.8±9.2 months. Results. In combatant-women with contusion in history, there are disturbances in the receptivity of the endometrium, manifested by abnormalities in the development of pinopodia and their microvilli during the implantation window: areas without pinopodia in 47.50% of cases (p<0.006), pinopodia of sizes – in 77.50% (p<0.01) and abundant microvilli – in 37.50% (p<0.02); a decrease in the frequency of the presence of developed pinopodia by 2.12 times (p<0.01), large pinopodia by 2.29 (p<0.01), and a small number of microvilli by 4.00 (p<0.0001), an increase in the occurrence of medium-sized pinopodia by 3.00 (p<0.02) times, and a moderate number of microvilli by 4.00 (p<0.0001). A characteristic feature of endometrial pinopodia in the above patients is the presence of mosaicism of their shape (65.00%) and size (67.50%). Conclusions. Women in the military who have been injured in combat are diagnosed with reproductive health problems caused by both the traumatic brain injury itself and the stressors associated with military service. Keywords: reproductive health, female veterans, post-contusion syndrome, receptive endometrial enlargement, office hysteroscopy.

scholarly journals Bleeding

2020 ◽  
Author(s):  
Kizito Omona
Keyword(s):  
Quality Of Life ◽  
At Risk ◽  
Abdominal Pain ◽  
Sexual Intercourse ◽  
Pelvic Pain ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Abnormal Bleeding ◽  
Monthly Period

Fibroid, also called leiomyomas, is common tumor of the uterus. Usually, women of reproductive age are at risk of getting it. However, majority of these women develop fibroid (s) by the age of 50 years. This condition usually causes painful and unpleasant symptoms such as; heavy bleeding, prolonged periods, inter-menstrual bleeding, abdominal pain and cramps, anemia, pelvic pain and pain during sexual intercourse, among others. Abnormal bleeding, such as bleeding that occurs with fibroids and heavy periods, often lasts more than 10 days per month. This fibroid symptom involves persistent bleeding between cycles, which can severely impact one’s quality of life. Abnormal bleeding, especially in fibroids, can be taken as missing three or more periods in a woman who had been having regular monthly period, or periods that last less than 21 days or more than 35 days apart from each other. Another indication of an abnormal period is bleeding through multiple pads and tampons in a short amount of time.

Management of vitamin D deficiency in patients with dyshormonal combined proliferative diseases of the reproductive organs

2018 ◽  
pp. 14-18
Author(s):  
S.O. Shurpyak ◽  
Keyword(s):  
Vitamin D ◽  
Blood Serum ◽  
Vitamin D Deficiency ◽  
Reproductive Function ◽  
Reproductive Organs ◽  
Reproductive Age ◽  
Operative Laparoscopy ◽  
Differential Correction ◽  
Increased Risk ◽  
Preventive Examination

The lack of vitamin D, according to WHO, is a pandemic. Studies conducted in different countries show the problem of vitamin D deficiency regardless of geographical latitudes in people of different age, nationality, vitamin D intake with food, even in those countries where there is no shortage of sunny days. Low level of vitamin D is considered as an independent predictor of the formation and progression of obesity, insulin resistance, PCOS, increased risk of endometriosis, uterine leiomyoma. Along with the influence on many vital processes in the human body, vitamin D plays a very important role in regulating the reproductive function of women. D-hormone affects the reproductive organs both directly, by binding to receptors (VDR), and mediated, through stimulation of the synthesis of steroid hormones and other effects. The objective: to study the effectiveness of clinical management of vitamin D deficiency in women with combined dyshormonal proliferative diseases of the reproductive organs. Materials and methods. The study involved 350 women of active and late reproductive age, residents of the Lviv region, who applied for preventive examination or with complaints of menstrual irregularity, infertility, miscarriage, chronic pelvic pain. The complex examination included ultrasonographic screening of the pelvic organs, mammary glands, thyroid gland, for hysteroscopy, endometrial needle biopsy, diagnostic / operative laparoscopy. Level 25(OH)D in the serum was determined by the enzyme immunoassay. I group consisted of 50 women without gynecological and concomitant pathology at the time of enrollment, group II – 300 patients with dyshormonal proliferative pathology of the reproductive organs. Results. Level 25(OH)D in the blood serum averaged 33.8±2.5 ng/ml occurred in 62.0% of women without gynecological pathology and only in 21.6% of women with dyshormonal pathology of the reproductive organs, lack of vitamin D(25(OH)D 22.3±1.5 ng/ml) was detected in 24.0% and 37.7%, respectively. Deficiency of vitamin D(25(OH)D 13.8±4.6 ng/ml) in women without gynecological and somatic pathology was diagnosed in 5.0% of cases and in 36.3% of women with benign proliferative pathology of reproductive organs (p<0.0001), with a severe deficit of vitamin D(25(OH)D in the serum from 4 to 9 ng/ml occurred in 73.7% of the latter.) A differential correction of vitamin D deficiency and deficiency with the use of preventive and curative doses of cholecalciferol Сonclusion. The dose of cholecalciferol (vitamin D3) 2000 IU/day is a sufficient preventive dose with an initial adequate level of vitamin D, but insufficient to eliminate its deficiency. Admission cholecalciferol in a daily dose of 100 mcg (4000 IU) with vitamin D deficiency allows after 3 months to reach 25–28 ng/ml 25(OH)D in the blood serum, but does not result in the level of 25(OH)D 40–50 ng/ml. Admission of 6000 IU/day cholecalciferol with severe vitamin D deficiency allows to reach 25(OH)D 40–50 ng/ml on average after 2.8±1.2 months in the absence of undesirable effects. Key words: vitamin D, vitamin D deficiency, combined dyshormonal proliferative diseases of the reproductive organs, cholecalciferol.

scholarly journals Laparoscopic evaluation of female infertility in low socioeconomic status

2018 ◽  
Vol 7 (8) ◽  
pp. 3232
Author(s):  
Chesta Saini ◽  
Ashoo Gupta ◽  
Kishore Rajurkar ◽  
Kartik Saxena ◽  
Kanchan Saini ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Low Socioeconomic Status ◽  
Inflammatory Disease ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Low Socioeconomic ◽  
Infertile Women ◽  
Major Factors ◽  
Reproductive Age Group

Background: Infertility is a multidimensional health issue which is rising dramatically. The common causes include ovarian, uterine, tubal disorders, hormonal imbalance, age-related factors and lifestyle factors. The low economic strata poses a subset of problems like difficulty in seeking healthcare, treatment costs and poor compliance. Authors sought to evaluate the factors for primary and secondary infertility in women of reproductive age group who belong to low socio-economic strata using laparoscopy.Methods: A prospective observational study was conducted in the obstetrics and gynaecology department at Sanjay Gandhi memorial hospital, Delhi comprising 50 infertile women of reproductive age group belonging to low socioeconomic class for a period of 2 years from June 2015 onwards.Results: Among primary infertility, tuberculosis (27.02%), ovarian cyst (16.22%), adhesions (10.81%), polycystic ovaries (10.81%) and Pelvic inflammatory disease (10.81%) were the major findings whereas in secondary infertility Pelvic inflammatory disease (23.07%), tuberculosis (15.38%), adhesions (15.38%) and endometriosis (7.69%) were the major factors seen in the study.Conclusions: Tuberculosis and pelvic inflammatory disease were the major factors seen in infertile women of low socioeconomic status thus, they should be kept high on the list of differential diagnosis even if the investigative work up is negative.

COMPLICATIONS OF PREGNANCY IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME

2011 ◽  
Vol 22 (3) ◽  
pp. 188-206
Author(s):  
MALLIKA AZIZIA ◽  
PAUL HARDIMAN
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Polycystic Ovaries ◽  
Women Of Reproductive Age ◽  
Ovary Syndrome ◽  
Ovarian Syndrome

Polycystic ovary syndrome (PCOS) is a common hormonal disorder affecting around 5–8% of women of reproductive age. It has a variable clinical spectrum including hyperandrogenism, menstrual abnormalities, polycystic ovaries and metabolic features like diabetes mellitus, obesity and dyslipidaemia. The manifestation of PCOS and its impact especially on reproductive function and pregnancy are profoundly affected by associated features of obesity/raised body mass index and metabolic syndrome.

scholarly journals Indicators of the reproductive function after endoscopic surgical treatment of uterine myomas

2020 ◽  
Vol 13 (4) ◽  
pp. 297-304
Author(s):  
M. M. Vysotskiy ◽  
I. I. Kuranov ◽  
O. B. Nevzorov
Keyword(s):  
Reproductive Function ◽  
Reproductive Age ◽  
Control Group ◽  
Women Of Reproductive Age ◽  
Hormone Production ◽  
Degree Of Malignancy ◽  
Main Factors ◽  
Group 2 ◽  
Almost All ◽  
Group 1

Aim: to characterize the function of the reproductive system in women after organ-preserving surgery for uterine myoma: hysteroresectoscopic (HRS) myomectomy and laparoscopic (LS) myomectomy.Materials and methods. Forty one patients were examined and divided into 2 groups: Group 1 – 18 patients after HRS myomectomy and Group 2 – 23 patients after LS myomectomy. The control group included 20 healthy women of reproductive age.Results. The HRS operation led to a significant decrease in the production of anti-Mullerian hormone (AMH), estradiol and progesterone, while the levels of luteinizing (LH) and follicle-stimulating (FSH) hormones increased. After myomectomy performed by the laparoscopic access, the levels of estradiol, progesterone, and AMH decreased but the levels of both LH and FSH increased so that the ratio LH/FSH remained unchanged. Almost all indices of gonadotropic and steroid hormone production became normalized over 6 months of the postoperative period.Conclusion. The main factors of unfavorable prognosis in patients with ovarian tecoma are tumor necrosis, degree of malignancy and mitotic activity.

scholarly journals Specific Aspects of Life Quality Estimation and Ways of Rehabilitation in Women Who Underwent Uterine Surgery

2016 ◽  
Vol 23 (3) ◽  
Author(s):  
H. M. Havrylyuk ◽  
O. M. Makarchuk
Keyword(s):  
Blood Supply ◽  
Ovarian Function ◽  
Internal Iliac Artery ◽  
Life Quality ◽  
Uterine Fibroids ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Internal Iliac

Recently, it has been noticed a great number of uterine fibroids in women with unrealized reproductive function; moreover, the number of combined forms of hyperplastic processes of the reproductive system in 20-25% of women under 30 years of age and 60% of women over 40 years of age is constantly growing creating a favourable background for cancer. It is also known that women with hyperplastic processes suffer from psycho-emotional disorders both before surgeries and after surgical recovery; many of them are diagnosed with adjustment disorder. As many researches note, the main psychotherapeutic aspects include passive view of life, increased anxiety, tendency to dependent behaviour, rejection of own body, protective behaviour and problems with self-assessment. It should also be noted that a comprehensive study of clinical and laboratory data and subjective criteria of life quality is essential in assessment of the feasibility of hysterectomy in women of reproductive age, even if they do not plan to bear children in the future. The objective of the research was to estimate life quality as well as to improve the system of dispensary observation and rehabilitation of women who underwent uterine surgery.Materials and methods. There was performed a comprehensive examination and surgical treatment of 60 women of reproductive age with uterine fibroid who underwent hysterectomy with preservation of appendages. We used modern high quality endocrinological and instrumental techniques. The assessment of the received data was made immediately after surgery, 6 and 2 months, 3 and 5 years after surgery. Quality of life was studied on the basis of a comprehensive assessment using the modified scale of the Nottingham Health Profile and the study of such important indicators as energy, sleep, emotional reactions, social isolation, physical activity, pain. All statistical analysis was performed using a standard package “Statistica for Windows – 6.0”.Results and discussion. On the basis of anamnestic data of patients we revealed health deterioration with high rates of liver and gastrointestinal tract disorders, metabolic disturbances (obesity, hypertensive disorders, fibrocystic breast disease), metabolic-endocrine changes and surgery. Reproductive health in women with uterine fibroid was characterized by long establishment of regular menstrual cycle, its breach in the period of puberty, inflammatory diseases of the genital organs, benign ovarian tumours and their surgical removal, inadequate reproductive behaviour with absent or delayed implementation of reproductive function and induced abortion. 12 months and especially 5 years after surgery there was noticed a progressive deterioration of the ovarian function, which was reflected as the reduction in their volume due to the reduction in the number and size of follicles, deterioration of blood supply to the ovaries, decreased blood flow in the internal iliac artery basin. It should also be noted the progressive hypestrogenism; in addition, there was a clear correlation with the age of the woman, who underwent surgical operation. Changes in life quality of patients with hyperplastic processes of the uterus were manifested in the postoperative period as follows: a decrease in physical activity (43.33% of cases), increased sexual dysfunction (36.66%), inhibition of mental state, conflict-orientated social behaviour, weakening of role functions and subjective deterioration of health and life quality (51.66% of cases).Conclusions. Thus, surgery on uterine fibroids with total or subtotal hysterectomy contributes to interference in a complex neuroendocrine interaction between hypothalamus, pituitary, ovaries, adrenal cortex, thyroid gland and affects the blood supply, innervation, and lymph efflux in the pelvic floor; therefore, postoperative syndromes are polyglandular and polysystemic. Long-term effects after surgery are accompanied by progressive hypestrogenism, decrease in the ovarian function (the reduction in their volume observed during ultrasound examination), reduction in the number and size of follicles, deterioration of blood supply to the ovaries, low blood supply to the internal iliac artery basin.

scholarly journals Restoring Reproductive Function In Overweight And Obese Women Of Childbearing Age

2020 ◽  
Vol 2 (08) ◽  
pp. 77-81
Author(s):  
Hamdamova M. T. ◽  
Jurakulova Z. A
Keyword(s):  
Negative Impact ◽  
Reproductive Function ◽  
Diet Therapy ◽  
Overweight And Obesity ◽  
Reproductive Age ◽  
Obese Women ◽  
Childbearing Age ◽  
Women Of Reproductive Age ◽  
Pregnancy And Childbirth ◽  
Group 2

The prevalence of overweight and obesity among women in Uzbekistan is 31.7 %. There is an annual increase in people with obesity. The facts of the negative impact of fat mass on the hormonal system and, as a result, a decrease in fertility in women are not in doubt. The purpose of this study was to evaluate the results of Metformin use in overweight and obese women of reproductive age. The study included 45 women of reproductive age who could not reduce weight with diet therapy. All patients were divided into three groups: group 1-planning pregnancy (n = 15), group 2 – having abnormal weight gain after childbirth (n = 15), group 3 – having overweight and obesity not related to pregnancy and childbirth (n = 15). Weight loss while taking Metformin increases fertility and should be performed in obese women as pre-gravidar training.

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