scholarly journals Sanation of carious and periapical foci in young athletes with impairment of cardiovascular adaptation

2014 ◽  
Vol 21 (2) ◽  
pp. 50-52
Author(s):  
I. I. Belyaev ◽  
G. A. Hatskevich
Keyword(s):  
Cardiovascular System ◽  
Clinical Signs ◽  
Exercise Stress ◽  
Young Athletes ◽  
System Adaptation ◽  
Optimal Period ◽  
Odontogenic Foci ◽  
The Impact ◽  
Sports Activities ◽  
Adaptation To Exercise

The aim of this study was to evaluate the impact of sanation of oral cavity in young athletes on the course of adaptation of the cardiovascular system to the condition of sports activities. According to the research results, it was revealed that the optimal period for sanation of periapical odontogenic foci in athletes with clinical signs of impairment (dysfunction) of cardiovascular system adaptation to exercise stress was a preparatory training period, while carious lesion sanation required preparatory or postcompetition periods.

scholarly journals Cardiovascular Adjustments during Graded Exercise Stress

2018 ◽  
Vol 1 (84) ◽  
Author(s):  
Jonas Poderys ◽  
Alfonsas Buliuolis ◽  
Vilma Papievienė
Keyword(s):  
Cardiovascular System ◽  
Exercise Stress ◽  
Bicycle Ergometry ◽  
Graded Exercise ◽  
System Adaptation ◽  
Cardiac Muscles ◽  
Adequate Blood Supply ◽  
Exercise Type ◽  
The Difference ◽  
Study Participants

Research background and hypothesis. Cardiac function provides an adequate blood supply to all organs thus changes in the performance and functional state of cardiac muscles during exercising are very important.Research aim. The aim of the study was to find out the peculiarities in adjustment of cardiovascular system in dependence on the type of adaptation to physical loads during graded stress.Research  methods.  The  study  participants,  17  non-athletes,  23  endurance,  19  sprint  and    21  combat  sport athletes, underwent a bicycle ergometry of incremental increase in provocative workload (graded stress). A 12-lead ECG was reordered and a computerized program allowed to measure ECG parameter, the ratio of JT/RR intervals and the velocity of adaptation of cardiovascular system to exercising (V Ad ), by calculating the difference between the relative changes of JT interval and RR interval as a difference: V Ad . = (JTi/JT0) 100% – (RRi/RR0) 100%.Research results. No significant functional ischemia was found in endurance cohort during the graded stress while it was expressed in non-athletes’ cohort and slightly smaller in sprint and combat cohorts. Maximal values of other ECG or ABP parameters registered during graded stress did not reveal significant differences between cohorts.Discussion  and  conclusions.  Functional  ischemia  is  an  important  factor  limiting  muscular  and  cardiac performance during the graded exercise stress. The exercise type plays a significant role in developing the velocity of adaptation of cardiovascular system at onset of exercising. Faster adaptation at onset of exercise is more characteristic of sprint and combat sports than representatives of endurance or non-athletes.Keywords: cardiovascular system, adaptation, functional ischemia.

scholarly journals Impact of connective tissue dysplasia on heart adaptation to exercise stress in young athletes

2020 ◽  
Vol 22 ◽  
pp. 02019
Author(s):  
Varvara Timokhina ◽  
Kamiliia Mekhdieva ◽  
Yulia Zinovieva ◽  
Vasily Chestukhin ◽  
Felix Blyakhman
Keyword(s):  
Connective Tissue ◽  
Stress Test ◽  
Exercise Stress ◽  
Regional Function ◽  
Young Athletes ◽  
Global Function ◽  
Connective Tissue Dysplasia ◽  
High Level ◽  
High Degree ◽  
Adaptation To Exercise

This study addresses the contribution of connective tissue dysplasia (CTD) to the cardiac function in young athletes. Thirty-three cross-country skiers aged 15 underwent maximum stress-ECG and TTE before and immediately after stress-test. Global and regional function of LV was evaluated with the use of further image processing. We found that 87.9 % of athletes had phenotypic markers of CTD ranged from 12 to 26 score points. Parameters of LV global function at rest in all studied athletes corresponded to normal age-gender values but markers of regional function showed high degree of mechanical asynchrony that depended on extent of CTD. All athletes passed stress-test successfully and demonstrated a high level of exercise performance. Meanwhile, the variables of LV pump-function and mechanical asynchrony close correlated with CTD extent. Obtained results imply that the increase of CTD extent was accompanied by the decrease of scale of heart adaptation to physical loads.

scholarly journals Morphofunctional features and physical fitness of boys 6 - 9 years old under the influence of various physical activity

2020 ◽  
Vol 26 ◽  
pp. 00014
Author(s):  
Tamara Abramova ◽  
Tatyana Nikitina ◽  
Anastasia Polfuntikova ◽  
Kristina Oblog ◽  
Faina Iordanskaya
Keyword(s):  
Physical Activity ◽  
Physical Fitness ◽  
Cardiovascular System ◽  
Physical Development ◽  
Growing Up ◽  
Young Athletes ◽  
Start Date ◽  
Positive Effect ◽  
Sports Activities

The aim of this research was to investigate morphofunctional features and physical fitness of boys 6 - 9 years old under the influence of various physical activity. The research performed in 2020 comprised 246 boys of 6 - 9 years old with different physical activity (121 children who are not involved in sports; 79 martial artists and 46 gymnasts with experience of 8 months and 4 years old). It was found that systematic sports activities of 6 - 9 years old boys have a positive effect on physical fitness and optimize morphofunctional indicators of physical development. The effect of the sport on the physical development and fitness of the boys depends on the start date and time of training sessions: a higher level of young gymnasts physical fitness is accompanied by a more intense adaptation of the cardiovascular system relative to martial artists. Differences in morphofunctional state and physical fitness between boys who are not involved in sports and young athletes are least significant in 6 year old boys, intensifying as growing up and increasing sport experience. It is more typical for gymnasts.

IDENTIFICATION AND ASSESSMENT OF RISK FACTORS ROLE IN MYOCARDIAL INFARCTION DEVELOPMENT

2019 ◽  
Vol 72 (5) ◽  
pp. 779-783
Author(s):  
Victor A. Ognev ◽  
Anna A. Podpriadova ◽  
Anna V. Lisova
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Cardiovascular System ◽  
Control Group ◽  
Biological Factors ◽  
Prevention And Treatment ◽  
High Level ◽  
Social Importance ◽  
The Impact

Introduction:The high level of morbidity and mortality from cardiovascular disease is largely due toinsufficient influence on the main risk factors that contribute to the development of myocardial infarction.Therefore, a detailed study and assessment of risk factors is among the most important problems of medical and social importance. The aim: To study and evaluate the impact of biological, social and hygienic, social and economic, psychological, natural and climatic risk factors on the development of myocardial infarction. Materials and methods: A sociological survey was conducted in 500 people aged 34 to 85. They were divided into two groups. The main group consisted of 310 patients with myocardial infarction. The control group consisted of 190 practically healthy people, identical by age, gender and other parameters, without diseases of the cardiovascular system. Results: It was defined that 30 factors have a significant impact on the development of myocardial infarction.Data analysis revealed that the leading risk factors for myocardial infarction were biological and socio-hygienic. The main biological factors were: hypertension and hypercholesterolemia. The man socio-hygienic factor was smoking. Conclusions: Identification of risk factors provides new opportunities for the development of more effective approaches for the prevention and treatment of myocardial infarction.

scholarly journals The Impact of Fluid Loss and Carbohydrate Consumption during Exercise, on Young Cyclists’ Fatigue Perception in Relation to Training Load Level

2021 ◽  
Vol 18 (6) ◽  
pp. 3282
Author(s):  
Leonardo Cesanelli ◽  
Berta Ylaitė ◽  
Giuseppe Messina ◽  
Daniele Zangla ◽  
Stefania Cataldi ◽  
...  
Keyword(s):  
Perceived Exertion ◽  
Wide Spectrum ◽  
Load Level ◽  
Training Load ◽  
Fluid Loss ◽  
Young Athletes ◽  
Carbohydrate Consumption ◽  
Significant Difference ◽  
Training Impulse ◽  
The Impact

High-level young athletes need to face a wide spectrum of stressors on their journey to élite categories. The aims of the present study are (i) to evaluate session rate of perceived exertion (sRPE) at different training impulse (TRIMP) categories and the correlations between these two variables and, (ii) evaluate the correlations between sRPE, fluid loss, and carbohydrate consumption during exercise. Data on Edward’s TRIMP, sRPE, body mass loss pre- and post- exercise (∆), and carbohydrate consumption (CHO/h) during exercise have been acquired from eight male junior cyclists during a competitive season. One-way ANOVA and correlation analysis with linear regression have been performed on acquired data. sRPE resulted in a significant difference in the three TRIMP categories (p < 0.001). sRPE resulted in being very largely positively associated with TRIMP values (p < 0.001; R = 0.71). ∆ as well as CHO/h was largely negatively related with sRPE in all TRIMP categories (p < 0.001). The results confirmed the role of fluid balance and carbohydrate consumption on the perception of fatigue and fatigue accumulation dynamics independently from the training load. Young athletes’ training load monitoring and nutritional-hydration support represent important aspects in athlete’s exercise-induced fatigue management.

scholarly journals SARS-CoV-2/DENV co-infection: a series of cases from the Federal District, Midwestern Brazil

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Heidi Luise Schulte ◽  
José Diego Brito-Sousa ◽  
Marcus Vinicius Guimarães Lacerda ◽  
Luciana Ansaneli Naves ◽  
Eliana Teles de Gois ◽  
...  
Keyword(s):  
Clinical Signs ◽  
Federal District ◽  
Therapeutic Interventions ◽  
Diagnostic Process ◽  
The Novel ◽  
Prevention Measures ◽  
Laboratory Findings ◽  
Novel Coronavirus ◽  
The Impact

Abstract Background Since the novel coronavirus disease outbreak, over 179.7 million people have been infected by SARS-CoV-2 worldwide, including the population living in dengue-endemic regions, particularly Latin America and Southeast Asia, raising concern about the impact of possible co-infections. Methods Thirteen SARS-CoV-2/DENV co-infection cases reported in Midwestern Brazil between April and September of 2020 are described. Information was gathered from hospital medical records regarding the most relevant clinical and laboratory findings, diagnostic process, therapeutic interventions, together with clinician-assessed outcomes and follow-up. Results Of the 13 cases, seven patients presented Acute Undifferentiated Febrile Syndrome and six had pre-existing co-morbidities, such as diabetes, hypertension and hypopituitarism. Two patients were pregnant. The most common symptoms and clinical signs reported at first evaluation were myalgia, fever and dyspnea. In six cases, the initial diagnosis was dengue fever, which delayed the diagnosis of concomitant infections. The most frequently applied therapeutic interventions were antibiotics and analgesics. In total, four patients were hospitalized. None of them were transferred to the intensive care unit or died. Clinical improvement was verified in all patients after a maximum of 21 days. Conclusions The cases reported here highlight the challenges in differential diagnosis and the importance of considering concomitant infections, especially to improve clinical management and possible prevention measures. Failure to consider a SARS-CoV-2/DENV co-infection may impact both individual and community levels, especially in endemic areas.

scholarly journals A 7-month inhalation toxicology study in C57BL/6 mice demonstrates reduced pulmonary inflammation and emphysematous changes following smoking cessation or switching to e-vapor products

2021 ◽  
Vol 5 ◽  
pp. 239784732199587
Author(s):  
Ashutosh Kumar ◽  
Ulrike Kogel ◽  
Marja Talikka ◽  
Celine Merg ◽  
Emmanuel Guedj ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Cigarette Smoke ◽  
Pulmonary Inflammation ◽  
Clinical Signs ◽  
Inhalation Study ◽  
Toxicology Study ◽  
Nasal Tissue ◽  
Product Switching ◽  
The Impact

Cigarette smoking causes serious diseases, including lung cancer, atherosclerotic coronary artery disease, peripheral vascular disease, chronic bronchitis, and emphysema. While cessation remains the most effective approach to minimize smoking-related disease, alternative non-combustible tobacco-derived nicotine-containing products may reduce disease risks among those unable or unwilling to quit. E-vapor aerosols typically contain significantly lower levels of smoke-related harmful and potentially harmful constituents; however, health risks of long-term inhalation exposures are unknown. We designed a 7-month inhalation study in C57BL/6 mice to evaluate long-term respiratory toxicity of e-vapor aerosols compared to cigarette smoke and to assess the impact of smoking cessation (Cessation group) or switching to an e-vapor product (Switching group) after 3 months of exposure to 3R4F cigarette smoke (CS). There were no significant changes in in-life observations (body weights, clinical signs) in e-vapor groups compared to the Sham Control. The 3R4F CS group showed reduced respiratory function during exposure and had lower body weight and showed transient signs of distress post-exposure. Following 7 months of exposure, e-vapor aerosols resulted in no or minimal increase in pulmonary inflammation, while exposure to 3R4F CS led to impairment of lung function and caused marked lung inflammation and emphysematous changes. Biological changes observed in the Switching group were similar to the Cessation group. 3R4F CS exposure dysregulated the lung and nasal tissue transcriptome, while these molecular effects were substantially lower in the e-vapor group. Results from this study demonstrate that in comparison with 3R4F CS, e-vapor aerosols induce substantially lower biological responses including pulmonary inflammation and emphysematous changes, and that complete switching from CS to e-vapor products significantly reduces biological changes associated with CS in C57BL/6 mice.

scholarly journals New onset of atrial fibrillation in cardiogenic shock

2021 ◽  
Vol 10 (Supplement_1) ◽  
Author(s):  
H Santos ◽  
T Vieira ◽  
J Fernandes ◽  
AR Ferreira ◽  
M Rios ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cardiogenic Shock ◽  
Linear Regression Analysis ◽  
Clinical Signs ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Coronary Syndrome ◽  
The Impact ◽  
New Onset

Abstract Funding Acknowledgements Type of funding sources: None. Introduction The development of cardiogenic shock (CS) is associated with worse prognosis, and can produce several hemodynamic manifestations. Then, is not surprised the manifestation of new-onset atrial fibrillation (AF) in these patients. Purpose Evaluate the impact of cardiovascular previous history, clinical signs and diagnosis procedures at admission as predictors of new-onset of AF in CS. Methods Single-centre retrospective study, engaging patients hospitalized for CS between 1/01/2014-30/10/2018. 222 patients with CS are included, 40 of them presented new onset of AF. Chi-square test, T-student test and Mann-Whitney U test were used to compare categorical and continuous variables. Multiple linear regression analysis was performed to evaluate predictors of new-onset AF in CS patients. Results CS patients without AF had a mean age of 61.08 ± 13.77 years old, on the other hand new-onset of AF patients in the setting of CS had a mean age of 67.02 ± 14.21 years old (p = 0.016). Nevertheless, no differences between the two groups was detected regarding the sex cardiovascular history (namely arterial hypertension, diabetes, dyslipidemia, obesity, smoker status, alcohol intake, previous acute coronary syndrome, history of angina, previous cardiomyopathy), neoplasia history, cardiac arrest during the CS, clinical signs at admission (like heart rate, blood pressure, respiratory rate), blood results (hemoglobin, leukocytes, troponin, creatinine, C-Reactive protein), left ventricular ejection fraction and the culprit lesion. New-onset of AF in CS patient had not impact in mortality rates. Multiple logistic regression reveals that only age was a predictor of new onset of AF in CS patients (odds ratio 1.032, confident interval 1.004-1.060, p = 0.024). Conclusions Age was the best predictor of new-onset AF in CS patients. The presence of this arrhythmia can have a hemodynamic impact, however, seems not influenced the final outcome.

scholarly journals African Swine Fever Laboratory Diagnosis—Lessons Learned from Recent Animal Trials

Pathogens ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 177
Author(s):  
Jutta Pikalo ◽  
Paul Deutschmann ◽  
Melina Fischer ◽  
Hanna Roszyk ◽  
Martin Beer ◽  
...  
Keyword(s):  
African Swine Fever Virus ◽  
Clinical Signs ◽  
African Swine Fever ◽  
Laboratory Diagnosis ◽  
Lessons Learned ◽  
Hemorrhagic Disease ◽  
Passive Surveillance ◽  
Animal Trials ◽  
Fit For Purpose ◽  
The Impact

African swine fever virus (ASFV) causes a hemorrhagic disease in pigs with high socio-economic consequences. To lower the impact of disease incursions, early detection is crucial. In the context of experimental animal trials, we evaluated diagnostic workflows for a high sample throughput in active surveillance, alternative sample matrices for passive surveillance, and lateral flow devices (LFD) for rapid testing. We could demonstrate that EDTA blood is significantly better suited for early ASFV detection than serum. Tissues recommended by the respective diagnostic manuals were in general comparable in their performance, with spleen samples giving best results. Superficial lymph nodes, ear punches, and different blood swabs were also evaluated as potential alternatives. In summary, all matrices yielded positive results at the peak of clinical signs and could be fit for purpose in passive surveillance. However, weaknesses were discovered for some matrices when it comes to the early phase of infection or recovery. The antigen LFD showed variable results with best performance in the clinical phase. The antibody LFD was quite comparable with ELISA systems. Concluding, alternative approaches are feasible but have to be embedded in control strategies selecting test methods and sample materials following a “fit-for-purpose” approach.

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