scholarly journals Differences of Misoprostol and Oxytocin Effect on Cervical Ripening

2020 ◽  
Vol 3 (2) ◽  
pp. 112-115
Author(s):  
Imelda Yunitra ◽  
Putri Sri Lasmini ◽  
Hafni Bachtiar
Keyword(s):  
Experimental Study ◽  
Folic Acid ◽  
Normal Pregnancy ◽  
Cervical Ripening ◽  
Control Group ◽  
Bishop Score ◽  
Dependent Variables ◽  
The Difference ◽  
Secondary Hospital ◽  
Dent Variable

Many studies has been done to determine the effectiveness of misoprostol and oxytocin even comparing the use of them for the induction of labor. Based on those studies, there seems to be a different effect of misoprostol and oxytocin on different phase of parturition, start from cervical ripening, uterine contrac- tion and successful labor. Compared to oxytocin as cervical ripening agent, misoprostol is more avail- able, cheaper, and effective. This study was an experimental study using pre-post control group to eval- uate the difference of misoprostol and oxytocin effect on cervical ripening. This study was conducted at RSUP DR. M. Djamil Padang and Secondary Hospital in periode of January-October 2014. Indepen- dent variable was cervical ripening using misoprostol 25 µg and oxytocin drip. Dependent variables are the event of cervical ripening and the increase of Bishop score. The average of cervical ripening using misoprostol was higher than oxytocin with 7,0968 ± 2,11904, compared to 2,5806±3,36427. This difference was significantly different with p > 0.05. It can be concluded that misoprostol is a better cer- vical ripening agent than oxytocin. Oxytocin is better given to ripe cervixKeywords: severe preeclampsia, folic acid, normal pregnancy

scholarly journals The role of oral mifepristone in pre-induction cervical ripening at term

2019 ◽  
Vol 8 (11) ◽  
pp. 4337
Author(s):  
Uma H. Chourasia ◽  
Mudita Kamlesh Jain ◽  
Juzar I. Fidvi
Keyword(s):  
Placebo Group ◽  
Labor Induction ◽  
Cervical Ripening ◽  
Controlled Study ◽  
Control Group ◽  
Study Group ◽  
Bishop Score ◽  
The Difference ◽  
Pg E2 ◽  
To Receive

Background: Planned induction of labor is an established part of modern obstetrics and is used as a definite form of treatment where continuation of pregnancy would be detrimental to the health of mother or fetus. The objective of this study was to evaluate the effect of mifepristone in pre-induction cervical ripening and labor induction.Methods: A total of 200 pregnant women at term with Bishop Score 4 or less were selected for this prospective randomized placebo-controlled study. The sample was equally divided into study group to receive 200 mg of mifepristone and control group to receive placebo orally for 2 days. Bishop score was assessed at every 24 hours interval till patient entered in spontaneous labor or 72 hours after 1st dose. Women who did not enter labor spontaneously, labor induction was planned with per vaginal insertion of prostaglandin (PG) E2 analogue, Dinoprostone gel 2.5 mg or PGE1 analogue Tab. Misoprostol 25 µg.Results: Ninety-six subjects in the study group and eighty-one in the control achieved successful ripening of cervix and the difference was statistically significant. Sixty-eight of study group and thirty-nine of placebo group entered in spontaneous active labor within 72 hours. Requirement of oxytocin as adjuvant treatment was significantly lower in the study group. Nineteen women of study group and fifteen of control group delivered within 24 hours, and eighty-one of study group and sixty-two of placebo delivered in 48 hours. The mean induction delivery interval was 35.53±13.67 hours in the study group, whereas it was significantly prolonged in the placebo group 50.49±20.92 hours. Eighty-two subjects of study group and seventy-eight of the control group delivered vaginally, the differences were statistically not significant.Conclusions: Mifepristone was found to be an effective agent for cervical priming prior to labor induction in women at term and significantly reduces the induction delivery interval compared with placebo.

Is it Possible to Prevent Cleft Palate by Prenatal Administration of Folic Acid? An Experimental Study

2001 ◽  
Vol 38 (4) ◽  
pp. 393-398 ◽  
Author(s):  
Volker Bienengräber ◽  
Fathi A. Malek ◽  
Klaus-Uwe Möritz ◽  
Jochen Fanghänel ◽  
Karsten K. H. Gundlach ◽  
...  
Keyword(s):  
Experimental Study ◽  
Folic Acid ◽  
Cleft Palate ◽  
Cleft Lip ◽  
Caesarian Section ◽  
Control Group ◽  
Fetal Head ◽  
Pregnant Rats ◽  
Experimentally Induced

Objective: In this study, folic acid was tested for its antiteratogenic effects on experimentally induced cleft palate in animals. Design: Eleven pregnant Lew 1 A dams (75 fetuses) received 200 mg/kg procarbazine via gastric tubing on postconception (p.c.) day 14 to induce a cleft palate (CP); seven of the pregnant dams (45 fetuses) were additionally given 4 mg/kg folic acid subcutaneously from the 14th to the 17th day p.c. As a control group, three more pregnant dams (24 fetuses) were not treated with the drugs mentioned above. All fetuses were delivered by Caesarian section on day 20 p.c. Outcomes measured: All fetuses were weighed and examined macroscopically with a stereomicroscope. Each fetal head was cut into 35 frontal sections and scrutinized histologically. Results: None of the control fetuses (n = 24) exhibited a cleft. Without folate administration, 90% of the fetuses (27 of 30) that received procarbazine exhibited a CP. After additional prenatal folate administration, this rate remained virtually unchanged (91%; 41 of 45). However, the proportion of complete (total) CP (4%) was significantly (p < .0001) lower than in the group without folate (53%). Cleft-associated microgenia and microglossia were also significantly less frequent when folate was administered prenatally: microgenia was reduced by 22% (p = .029) and microglossia by 24% (p = .032). Conclusions: On the basis of these results, folate has a partial ameliorating effect on the teratogenicity of procarbazine given to pregnant rats. Additional studies are necessary on the effect of folate in different species, also taking cleft lip and CP into consideration.

scholarly journals EFFECTIVENESS ABOUT TECHNIQUES OF PUZZLE GAMES IN UNDERSTANDING THE CONCEPT WHEN LEARNING SOCIAL SCIENE AT JUNIOR HIGH SCHOOL OF 40 BANDUNG (Quasi Experimental Study at Junior High School of 40 Bandung)

2018 ◽  
Vol 2 (2) ◽  
pp. 63
Author(s):  
Yosefin Candra Erladini
Keyword(s):  
High School ◽  
Experimental Study ◽  
Junior High School ◽  
Junior High ◽  
Hypothesis Test ◽  
Control Group ◽  
Before And After ◽  
Quasi Experimental ◽  
The Difference ◽  
Puzzle Games

Abstract-The present study was motivated by the author’s eagerness to investigate the effectiveness about  techniques of puzzle games in understanding the concept when learning social sciene at Junior High School of 40 Bandung. This research was aimed to explain the ability of understanding the concept when learning social sciene before and after applying the techniques of puzzle games, explaining the effect from techniques of puzzle games when learning social sciene, and showing the effectiveness from techniques of puzzle games when learning social sciene. The study employed quasi experimental study with the design of pretest-posttest control group. According to hypothesis test showed the difference between the ability of understanding the concept social sciene at experimental class and the capability at controlled class, after the experimental class being given techniques of puzzle games treatment when learning social sciene. Consequently, it can be conclude that implementing the techniques of puzzle games was really effective to be used in understanding the concept when learning social sciene.Keywords: Techniques of puzzle games, The understanding of concept, Sosial sciene.

scholarly journals Impact evaluation of biomedical waste segregation among junior residents of a South Indian medical college: a quasi experimental study

2020 ◽  
Vol 7 (7) ◽  
pp. 2513
Author(s):  
Ranganath T. Sobagaiah ◽  
Karuna Siddappa Patange ◽  
Vishwanatha .
Keyword(s):  
Experimental Study ◽  
T Test ◽  
Control Group ◽  
Junior Doctors ◽  
Human Beings ◽  
Biomedical Waste ◽  
Quasi Experimental ◽  
Waste Segregation ◽  
The Difference ◽  
The Impact

Background: Biomedical waste is any waste generated during the diagnosis, treatment or immunization of human beings or animals. The quantity of solid waste generated in Bangalore hospitals is from ½ to 4 kg per bed per day. But segregation is done in only 30%. Health care workers have an important responsibility to segregate the biomedical waste and dispose them. Hence this study was undertaken with the objective of assessing the impact of intervention on Biomedical waste segregation knowledge among junior doctors.  Methods: The study design employed is a quasi experimental study with control and intervention design. The junior doctors were selected randomly. After written informed consent the participants were divided as two group of intervention and control group with 74 in each group. Data of pre-test was collected using self-administered and validated questionnaire. After a week of pre-test, training using WHO modules 3 on training of biomedical waste segregation based on IHWM was done only for the intervention group. After a period of 3 months post test was conducted for both the intervention and the control group using a pre tested self-administered questionnaire with questions very similar to the pre-test.Results: The difference is found to be with t-test value of 1.434 and df of 37 with significant value 0.160 (>0.05) for the control group. The difference is found to be with t-test value of 3.241 and df of 35 with significant value 0.003 (<0.05) for the intervention group.Conclusions: The knowledge of biomedical waste management was found to increase after an intervention.

scholarly journals Effect of Antenatal Anaemia of the Mother on the Volume of the Placenta

1970 ◽  
Vol 2 (1) ◽  
pp. 22-25
Author(s):  
Mahamuda Begum ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Shamim Ara ◽  
Gul Newaz Begum
Keyword(s):  
Haemoglobin Concentration ◽  
Normal Pregnancy ◽  
Control Group ◽  
Water Displacement ◽  
College Hospital ◽  
Maternal Anaemia ◽  
Medical College ◽  
Group A ◽  
The Difference ◽  
A Prospective Study

In pregnancy, anaemia has a tremendous effect on the placenta. Maternal anaemia increases the volume of the placenta. Foetal hypoxaemia usually develops as a consequence of maternal anaemia, due to lower haemoglobin concentration, and stimulates placental growth. A prospective study was carried out in the Department of Obstetrics & Gynaecology, Dhaka Medical College Hospital and Maternal and Child Health Training Institute (widely known as Azimpur Maternity), Dhaka, Bangladesh, from August 2005 to June 2006 on 60 Bangladeshi women who were within 35-40 weeks of gestation. Among them, 20 had normal uncomplicated pregnancies (considered as control group or group A) and another 27 had pregnancies with mild anaemia (considered as group B1) and 13 had pregnancies with moderate anaemia (considered as group B2). Severe anaemic (considered as group B3) mother was not found during the period of collection of data for this study. The mothers were selected as who were suffering from antenatal anaemia i.e. having heamoglobin level <10 gm/dl (mild, if <10 gm/dl; moderate, if <8 gm/dl; and severe, if <6 gm/dl) and control i.e. having heamoglobin level ≥10 gm/dl. The placentae of the mothers were collected after delivery and their volume were measured by water displacement method and recorded. The present study showed that mean volume of placenta in group A, group B1 and group B2 were 444.00±38.37, 472.59±17.34 and 485.38±24.62 ml respectively. The difference between group A & B1, and A & B2 were found statistically significant. The volume of the placenta was found to increase with ascending grade of antenatal naemia of mothers in comparison to that of normal pregnancy. Key Words: Antenatal Anaemia; Maternal Anaemia; Volume of Placenta DOI: 10.3329/akmmcj.v2i1.7467 Anwer Khan Modern Medical College Journal 2011; 2(1): 22-25

scholarly journals Effects of Progressive Muscle Relaxation on Concentration and Performance Scores of 10m Shooters

2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Novrizal Achmad Novan ◽  
Nandya Indriana Adha Irianto ◽  
Komarudin Komarudin ◽  
Patriana Nurmansyah Awwaludin
Keyword(s):  
Performance Test ◽  
Muscle Relaxation ◽  
Self Control ◽  
Progressive Muscle Relaxation ◽  
Control Group ◽  
Training Methods ◽  
Main Effect ◽  
Dependent Variables ◽  
The Difference ◽  
And Performance

Shooting skills are complex. Athletes often have to face a situation requiring one shot to get a perfect score and maintain concentration and the trigger pull. This study aimed to analyze the difference in progressive muscle relaxation (PMR) exercise on increasing concentration and performance scores of 10-meter shooting. A total of 12 athletes (seven female dan five males) in Purwakarta were recruited for this study. They were randomly assigned to the PMR group (n = 6) and the control group (n = 6). The instruments used were the Concentration Grid Test for measuring concentration and the scores of 60 shots of the 10-meter shooting of both men and women for a performance test. Data analysis using MANCOVA was performed using shooting and concentration scores as the dependent variables and covariates to determine their performance. They can be differentiated based on conventional training methods, progressive muscle relaxation, and the interaction of these factors. The results of the MANCOVA indicated a significant main effect for exercise methods. It was revealed that differences in exercise methods had a significant effect on concentration and shooting scores. When athletes face the demands of top performance, PMR training is an economical but efficient and effective strategy for dealing with the problems. It helps athletes to do the self-control and focus their attention during stressful situations. It also can be used to maintain physical, technical, and mental balances.

scholarly journals Efficacy and safety of oral mifepristone for cervical priming and induction of labor in term pregnancy

2018 ◽  
Vol 7 (7) ◽  
pp. 2766 ◽  
Author(s):  
Abhilasha Gupta ◽  
Aruna Verma ◽  
Iti Madan ◽  
Monika Kashyap
Keyword(s):  
Controlled Trial ◽  
Group Versus ◽  
Perinatal Outcomes ◽  
Active Phase ◽  
Cervical Ripening ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Bishop Score ◽  
Term Pregnancy

Background: The objectives of the study was to assess the efficacy of mifepristone in priming the cervix/inducing labor over next 96 hrs in term pregnancy.Methods: In this single blind randomized controlled trial 200 women with term pregnancy beyond 39 weeks and Bishop’ score <6 were randomly allocated into two groups. Tab Mifepristone 400 mg orally was given to women in study group (n=100) and no intervention in control group (n=100). On follow up one case was lost in control group. All women were observed for change in the bishop’s score or onset of labor in next 96 hrs. If Bishop’s score was <6, the choice of induction was left on the clinician/patient.Results: Mean induction to delivery interval, duration of active phase and improved Bishop score were 79.35±53.43 hr, 2.47±1.23 hr, 6.68±1.69 for study group versus 148±65.66 hr, 3.09±1.45 hr, 5.8±2.15  for control group (p value is <0.001) respectively.  Seventy one (71%) women in study group and 39 (39.3%) women in control group delivered vaginally within 96 hrs without any need of augmentation. There were 9 (9%) caesareans in study group and 24 (24.2%) caesareans in control group but no instrumental delivery in both groups. There was no statistically difference in perinatal outcomes between two groups.Conclusions: Mifepristone is an effective drug for cervical ripening and initiation of labor when given in term pregnancy beyond 39 weeks with poor Bishop’s score (<6) and appearing to reduce need for other agent for augmentation of labor.

Is It Possible to Enhance Intensity in Guided Imagery Exercises? An Experimental Study

2018 ◽  
Vol 32 (1) ◽  
pp. 38-48
Author(s):  
Laura Elise Seebauer ◽  
Eva Naumann ◽  
Anneke Jacobs ◽  
Myriam Thier ◽  
Gitta A. Jacob
Keyword(s):  
Experimental Study ◽  
Guided Imagery ◽  
Outcome Measure ◽  
Control Group ◽  
Emotional Intensity ◽  
Sympathetic Activation ◽  
Mental Images ◽  
Movie Clip ◽  
Dependent Variables ◽  
Healthy Participants

Objective:Guided imagery exercises can have a powerful impact on distressing mental images. Clinically, it is usually recommended to experience these exercises as intensely as possible. However, patients sometimes object to the related instructions. In this study, we tested whether typical clinical instructions aiming at increasing intensity led to a stronger effect of the exercise.Methods:Sixty-four healthy participants watched a trauma movie clip. Then they were pseudo-randomized into one of two strategies (intense, less intense) or a waiting control condition. Dependent variables were self-reported emotional intensity and psychophysiology measures.Results:Participants in the intense ImRS strategy did not experience the exercise as more intense than those in the less intense ImRS strategy on any outcome measure. Both ImRS strategies showed increased sympathetic activation compared to a decrease of activation in the waiting control group.Conclusions:Our results suggest that emotional intensity in guided imagery exercises may not depend very much on the therapist’s instructions.

Is it possible to antagonize 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin- induced cleft palate by prenatal administration of folic acid? An experimental study

2010 ◽  
Vol 26 (5) ◽  
pp. 281-286 ◽  
Author(s):  
Cheng-hao Li ◽  
Bing Shi ◽  
Wei He ◽  
Tian Meng
Keyword(s):  
Experimental Study ◽  
Body Weight ◽  
Folic Acid ◽  
Cleft Palate ◽  
Sesame Oil ◽  
Control Group ◽  
Total Frequency ◽  
Fetal Mice ◽  
Tetrachlorodibenzo P Dioxin

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) can cause a high percentage of cleft palate in fetuses when administered during organogenesis in certain strains of mice including C57BL/6J. In this study, folic acid (FA) was tested for antiteratogenic effects on TCDD-induced cleft palate in fetal mice. The pregnant C57BL/6J mice were dosed with 24 µg TCDD/kg and/or 5 mg, 10 mg, 20 mg, 40 mg FA/kg body weight on gestation day (GD) 10. The control group mice received 50 mL sesame oil/kg body weight on GD10. The mice were sacrificed on GD12.5, GD13.5, GD14.5, GD15.5, and GD16.5. The harvested embryos were examined to detect the incidence of cleft palate and the developing palatal shelves on different phases were investigated morphologically and histologically among different groups. Total frequency of clefts was 55.56% in TCDD group and 17.50% (5 mg), 42.85% (10 mg), 42.10% (20 mg), 28.26% (40 mg) in TCDD + FA groups. FA (5 mg) reduced the incidence of the cleft palate from 55.56% to 17.50% (p = 0.005). There were no significant differences between the TCDD group and 10 mg, 20 mg, 40 mg TCDD + FA groups. Based on the these results, the present study suggests that FA can reduce the incidence of 2,3,7,8-TCDD-indued cleft palate in mice.

scholarly journals Effects of Preeclampsia on Perinatal Outcome- A Study Done in the Specialized Urban Hospital Set Up in Bangladesh

1970 ◽  
Vol 40 (1) ◽  
pp. 33-36 ◽  
Author(s):  
S Kishwara ◽  
S Tanira ◽  
E Omar ◽  
F Wazed ◽  
S Ara
Keyword(s):  
Normal Pregnancy ◽  
Fetal Outcome ◽  
Control Group ◽  
Urban Hospital ◽  
College Hospital ◽  
Related Disorder ◽  
Group A ◽  
The Mean ◽  
The Difference ◽  
Group B

Preeclampsia is a common pregnancy related disorder in Bangladesh that originates in the placenta and causes variable maternal and fetal problems. A prospective study was designed to see the associated maternal factors and fetal outcome in preeclampsia and to compare with that of normal pregnancy. The study was done in the Department of Obstetrics & Gynaecology, Dhaka Medical College Hospital and Mitford Hospital, Dhaka, from August 2005 to June 2006. Sixty Bangladeshi pregnant women were taken in this study, of which thirty were normal uncomplicated pregnancies (considered as control group or group A) and another thirty having pregnancies complicated by preeclampsia (considered as preeclampsia group or group B), where the patients were normotensive previously. Both the maternal and fetal outcomes were observed and recorded. The mean age of the mother was 26.53±5.26 years and 26.67±5.27 years in group A and group B respectively. The mean gestational age of the mother was 38.27±1.26 weeks and 36.90±1.03 weeks in group A and group B respectively and the difference in between two groups was statistically significant (p<0.001). The mean birth weight of the neonate was 2.80±0.27 kg. and 2.26±0.41 kg. in group A and group B respectively and the difference was significant (p<0.001). The mean APGAR score of the neonate at one minute was 9.00±1.02 and 8.40±0.93 in group A and group B respectively and the difference was significant (p<0.05). DOI: http://dx.doi.org/10.3329/bmj.v40i1.9960 BMJ 2011; 40(1): 33-36

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