scholarly journals Can antimalarial, antiviral and anti-respiratory infections Cameroonian medicinal plants be used as one of the potential ways to cure COVID-19? Pharmacological and ethnomedicinal proof

2020 ◽  
pp. 61-85
Author(s):  
Tsobou Roger ◽  
Hamawa Yougouda ◽  
Fawa Guidawa ◽  
Tatsimo Ndendoung Simplice Joël ◽  
Avana Tientcheu Marie-Louise ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Viral Infections ◽  
Respiratory Infections ◽  
Curcuma Longa ◽  
Research Work ◽  
Zingiber Officinale ◽  
Traditional Healers ◽  
Global Public Health ◽  
Tract Infections

COVID-19 is a severe acute respiratory syndrome-related corona-virus SARS-CoV-2, that constitutes a pandemic threat to global public health. Unfortunately, there are no specific available therapies. This research work presents the findings of an investigation on traditional Cameroonian remedies of respiratory tract infections, malaria and viral infections, and also recipes that could serve as a baseline for the prevention, alleviate symptoms, treatment and perhaps may help for the anti-COVID-19 drugs discovery. Data on the medicinal plants were collected from traditional healers, Cameroonian medicinal plants books, the internet, and in addition to our personal experience as researchers and herbalists. Details of 85 plant species used to manage these three mentioned diseases in Cameroon and their pharmacological properties are recorded. Due to their ethnomedicinal uses and pharmacological activities, twenty-eight (28) plant species and 13 recipes are suggested for COVID-19 prevention, alleviate symptoms, treatment and baseline for anti-COVID-19 drug discovery. Amongst the proposed plants we have the following, Curcuma longa, Azadirachta indica, Zingiber officinale, Allium sativum and Ocimum gratissimum which were reported to possess certain inhibition properties against COVID-19 protease.

scholarly journals Candidate Anti-COVID-19 Medicinal Plants from Ethiopia: A Review of Plants Traditionally Used to Treat Viral Diseases

2021 ◽  
Vol 2021 ◽  
pp. 1-20
Author(s):  
Dires Tegen ◽  
Kindalem Dessie ◽  
Destaw Damtie
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Viral Infections ◽  
Epigallocatechin Gallate ◽  
Viral Diseases ◽  
Chemical Components ◽  
Ethnobotanical Study ◽  
Global Public Health ◽  
Active Components ◽  
Antiviral Activities

Background. Emerging viral infections are among the major global public health concerns. The pandemic COVID-19 is a contagious respiratory and vascular disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There are no medicines that can treat SARS-CoV-2 except the vaccines. Therefore, searching for plant-originated therapeutics for the treatment of COVID-19 is required. Consequently, reviewing medicinal plants used to treat different viral infections is mandatory. This review article aims to review the ethnobotanical knowledge of medicinal plants traditionally used to treat different viral diseases by the Ethiopian people and suggests those plants as candidates to fight COVID-19. Methods. Articles written in English were searched from online public databases using searching terms like “Traditional Medicine,” “Ethnobotanical study,” “Active components,” “Antiviral activities,” and “Ethiopia.” Ethnobotanical data were analyzed using the Excel statistical software program. Result. From the 46 articles reviewed, a total of 111 plant species were claimed to treat viral infections. Fifty-six (50.4%) of the plant species had reported to have antiviral active components that are promising to treat COVID-19. Lycorine, gingerol shogaol, resveratrol, rhoifolin, oleanolic acid, kaempferol, rosmarinic acid, almond oil, ursolic acid, hederagenin, nigellidine, α-hederin, apigenin, nobiletin, tangeretin, chalcone, hesperidin, epigallocatechin gallate, allicin, diallyl trisulfide, ajoene, aloenin, artemisinin, glucobrassicin, curcumin, piperine, flavonoids, anthraquinone, hydroxychloroquine, and jensenone were some of them. Conclusion. The Ethiopian traditional knowledge applies a lot of medicinal plants to treat different viral infections. Reports of the chemical components of many of them confirm that they can be promising to fight COVID-19.

scholarly journals Review of Antiviral Medicinal Plants used in Taraba State Nigeria: A Possible Source for COVID-19 Drug Discovery

2020 ◽  
Vol 1 (2) ◽  
pp. 1-23
Author(s):  
Cletus Anes Ukwubile ◽  
Troy Silvia Malgwi ◽  
Alexander Ezekiel Angyu ◽  
Otalu Otalu ◽  
Mathias Simon Bingari
Keyword(s):  
Medicinal Plants ◽  
Allium Sativum ◽  
Viral Infections ◽  
Curcuma Longa ◽  
Antiviral Agents ◽  
Zingiber Officinale ◽  
Human Influenza Virus ◽  
Infectious Bronchitis ◽  
The Usa ◽  
Ocimum Tenuiflorum

Purpose: Coronavirus also known as COVID-19 is a viral infection that has been tagged as the greatest pandemic since the existence of humans by the WHO, resulting in the deaths of thousands of people globally; with the USA one of the highest. The full biology of the virus is yet to be known. This study reviews sixteen natural antiviral plants used in Taraba State to manage viral infections locally. Subjects and Methods: Sixteen medicinal plants popularly used as antiviral agents in Taraba State, Nigeria were surveyed based on a field-trip experience with herbal medicine practitioners in the three zones of the state. Plants that were in both zones were counted as the same. The plants that are majorly used for various viral infections are Allium sativum, Zingiber officinale, Camellia sinensis, Hibiscus sabdariffa, Cirus lemon, Azardirachta indica, Ocimum tenuiflorum, Curcuma longa, Haematostaphis barteri, Olea europaea, Melastomastrum capitatum, Astragalus canadensis, Carissa edulis, Spondias venulosa, Vitellaria paradoxa, and Euphorbia hirta. Results: Of the sixteen plants, ten have been reported to have antiviral properties against at least one of these viruses avian or bird flu, human influenza virus, infectious bronchitis virus (a type of coronavirus), herpes virus, hepatitis C virus and HIV. Conclusion: The study revealed that further research on these antiviral plants used traditionally might pave the way for the discovery of potent antiviral drugs against COVID-19.

scholarly journals Ethnomedicinal uses of plants by Santal Tribal peoples at Nawabganj upazila of Dinajpur district, Bangladesh

2019 ◽  
Vol 26 (1) ◽  
pp. 117-126 ◽  
Author(s):  
Most. Rojuba Khatun ◽  
A.H.M. Mahbubur Rahman
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Traditional Healers ◽  
Field Trips ◽  
Age Group ◽  
Traditional Medicinal Plants ◽  
Whole Plant ◽  
Ethnomedicinal Uses ◽  
Herbal Formulations ◽  
Scientific Name

Ethnobotanical investigation on traditional medicinal plants used by Santal tribal people of Nawabganj upazila of Dinajpur district, Bangladesh was documented. Frequent field trips were made during January to December 2018 to record ethnobotanical data by interviewing Santals of various age group, mostly ranging between 20-76 years, including the traditional healers. A total of 105 plant species under 97 genera belonging to 57 families were recorded which are used by the Santals for the treatment of 67 ailments. Out of these plant species 44% belonged to herbs, 28% trees, 18% shrubs, 10% climbers. In herbal formulations, leaves were found to be mostly used (29%) followed by roots (12%), fruits (12%), whole plant (10%), seeds (9%), barks (9%), stems (5%), flowers (4%), latex (2%), rhizomes (2%), petioles (2%), gums (2%), bulbs (1%), tubers (1%), pods (1%) and buds (1%). The Santal medicinal wealth have been presented with scientific name, family, Bangla name, Santal name, part(s) used, ailments to be treated and formulations. This study also provides data on diversity, distribution and habitats for conservation and prioritization of the medicinal plants.

TRADITIONAL PHYTOTHERAPY USED BY BHUTIA COMMUNITY OF UTTARKASHI DISTRICT OF UTTARAKHAND FOR DERMATOLOGICAL DISORDERS

2021 ◽  
pp. 77-82
Author(s):  
Arun K. Agrawal ◽  
Usha Devi ◽  
S.K. Kuriyal
Keyword(s):  
Medicinal Plants ◽  
Indigenous Knowledge ◽  
Plant Species ◽  
Primary Healthcare ◽  
Skin Diseases ◽  
Practical Knowledge ◽  
Traditional Healers ◽  
Tribal Community ◽  
Tribal People ◽  
Dermatological Disorders

Ethno-medicinal survey was undertaken from traditional healers of Bhutia tribal community of Urrarkashi district for the use of medicinal plants in the treatment of different skin diseases such as dog and insect bite, burns, eczema, abscesses, scabies, ringworm, cuts and wounds, boils, leprosy, blisters, allergy, itching, pimples, leucoderma, prickly heat, warts, septic ulcers, and other skin diseases during different season of March 2016 to May 2017. The indigenous knowledge of tribal traditional healers having practical knowledge of plants in medicine were interviewed in ve villages of Uttarkashi district of Uttarakhand and plants used for medicinal purposes were collected through questionnaire and personal interviews during eldtrips. A total of 60 plant species of 43 families are documented in this study. The medicinal plants used in the treatment of skin diseases by tribal's are listed with botanical name (in binomial form), family, local names, habit, availability, parts used, and mode of preparation. This study showed that Bhutia tribal people in the studied parts of Uttarkashi district continue to depend on the medicinal plants at least for the treatment of primary healthcare.

scholarly journals Ethnobotanical study of medicinal plants of Resunga hill used by Magar community of Badagaun VDC, Gulmi district, Nepal

2012 ◽  
Vol 10 (10) ◽  
pp. 54-65 ◽  
Author(s):  
Rajendra Acharya
Keyword(s):  
Medicinal Plants ◽  
Respiratory Tract ◽  
Plant Species ◽  
Stem Bark ◽  
Traditional Healers ◽  
Easy Access ◽  
Ethnobotanical Study ◽  
Young Generation ◽  
Plant Parts ◽  
Scientific World

Present study aims to explore the ethnobotanical information on medicinal plants used by Magar community of Badagaun VDC of Gulmi district. The study was carried out during different periods of the year 2010. Informations on plant and plant parts uses were collected interviewing key informants by using semi-structured open-ended questionnaire. Altogether 161 different plant species belonging to 87 familes and 144 genera were documented and majority of them are herbs. In terms of plant parts use, leaf and stem/bark are in top priorities. These plants are used to treat different ailments ranging from gastro-intestinal to headache and fever, respiratory tract related problems to dermatological problems, snake bite to ophthalmic and cuts and wounds. Easy access to modern medicines and less recognition of traditional healers are the main causes leading to decrease in interest of young generation in the use of traditional medicinal practices. Scientific World, Vol. 10, No. 10, July 2012 p54-65 DOI: http://dx.doi.org/10.3126/sw.v10i10.6863

scholarly journals Potential Neurocognitive Symptoms Due to Respiratory Syncytial Virus Infection

Pathogens ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 47
Author(s):  
Catalina A. Andrade ◽  
Alexis M. Kalergis ◽  
Karen Bohmwald
Keyword(s):  
Respiratory Syncytial Virus ◽  
Viral Infections ◽  
Respiratory Infections ◽  
The Elderly ◽  
Cell Types ◽  
Potential Effect ◽  
Viral Agent ◽  
Pulmonary Manifestations ◽  
Syncytial Virus ◽  
Tract Infections

Respiratory infections are among the major public health burdens, especially during winter. Along these lines, the human respiratory syncytial virus (hRSV) is the principal viral agent causing acute lower respiratory tract infections leading to hospitalization. The pulmonary manifestations due to hRSV infection are bronchiolitis and pneumonia, where the population most affected are infants and the elderly. However, recent evidence suggests that hRSV infection can impact the mother and fetus during pregnancy. Studies have indicated that hRSV can infect different cell types from the placenta and even cross the placenta barrier and infect the fetus. In addition, it is known that infections during the gestational period can lead to severe consequences for the development of the fetus due not only to a direct viral infection but also because of maternal immune activation (MIA). Furthermore, it has been described that the development of the central nervous system (CNS) of the fetus can be affected by the inflammatory environment of the uterus caused by viral infections. Increasing evidence supports the notion that hRSV could invade the CNS and infect nervous cells, such as microglia, neurons, and astrocytes, promoting neuroinflammation. Moreover, it has been described that the hRSV infection can provoke neurological manifestations, including cognitive impairment and behavioral alterations. Here, we will review the potential effect of hRSV in brain development and the potential long-term neurological sequelae.

scholarly journals Clinical-epidemiological peculiarities of acute respiratory infections in children from 3 to 12 years and evaluation of effectiveness of antivirus therapy

2019 ◽  
Vol 11 (3) ◽  
pp. 38-45
Author(s):  
S. A. Khmilevskaya ◽  
N. I. Zryachkin ◽  
V. E. Mikhailova
Keyword(s):  
Viral Infections ◽  
Respiratory Infections ◽  
Molecular Genetic ◽  
Respiratory Viruses ◽  
Acute Respiratory Infections ◽  
Age Group ◽  
Leading Role ◽  
Respiratory Viral Infections ◽  
Acute Respiratory Viral Infection ◽  
Tract Infections

The aim: to study the etiological structure of acute respiratory infections in children aged 3 to 12 hospitalized in the early stages of the disease in the department of respiratory infections of the children’s hospital, and to reveal the features of their clinical course and the timing of DNA / RNA elimination of respiratory viruses from nasal secretions, depending on the method of therapy. Materials and methods: 100 children with acute respiratory infections aged 3 to 12 years were monitored. The nasal secrets on the DNA / RNA of respiratory viruses were studied by PCR. Depending on the method of therapy, patients were divided into 2 groups: patients of group 1 (comparison) received basic treatment (without the use of antiviral drugs), in patients of the 2nd group (main), along with basal therapy, the drug was used umifenovir in a 5-day course at the ageappropriate dosage. Results: In the etiologic structure of ARVI in children from 3 to 12 years, the leading place was taken by rhinovirus, influenza and metapneumovirus infections (isolated – 18%, 19% and 20% respectively, in the form of a mixed infection – 11%). The main syndromic diagnosis at the height of the disease was rhinopharyngitis. Complications were observed in 42% of cases, as often as possible with flu – 53% of cases. Features of metapneumovirus infection in children of this age group were: predominance of non-severe forms of the disease in the form of acute fever with symptoms of rhinopharyngitis, as well as a small incidence of lower respiratory tract infections. The use of the drug umiphenovir in children with acute respiratory viral infections of various etiologies contributed to significantly faster elimination of viral DNA / RNA from the nasal secretion, which was accompanied by a ecrease in the duration of the main clinical and hematological symptoms of the disease, a decrease in the incidence of complications, and reduced the duration of stay in hospital. Conclusion: application of modern molecular genetic methods of diagnostics made it possible to identify the leading role of influenza, metapneumovirus and rhinovirus infections in the etiology of acute respiratory viral infection in patients aged 3 to 12 years, and to determine a number of clinical features characteristic of this age group. The results of the study testify to the effectiveness of umiphenovir in the treatment of children with acute respiratory viral infections of various etiologies and allow us to recommend this drug as an effective and safe etiotropic agent.

scholarly journals Medicinal Plants Used by Traditional Healers in Algeria: A Multiregional Ethnobotanical Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Khadidja Belhouala ◽  
Bachir Benarba
Keyword(s):  
Medicinal Plants ◽  
Zingiber Officinale ◽  
Traditional Healers ◽  
Bioactive Molecules ◽  
Ethnobotanical Study ◽  
Medicinal Species ◽  
Face To Face ◽  
New Therapeutic Approaches ◽  
Informant Consensus ◽  
Therapeutic Uses

Traditional medicine is the cornerstone that boosts scientific research to explore new therapeutic approaches. The study aimed to assess the traditional knowledge and use of medicinal plants to treat various ailments by Algerian traditional healers. Forty traditional healers were face-to-face interviewed in three different Algerian areas (West, Kabylia, and Sahara). The data collected were analyzed using quantitative indices such as fidelity level (FL) and informant consensus factor (FIC). A total of 167 species belonging to 70 families were recorded. Lamiaceae (13%), Asteraceae (13%), Apiaceae (7%), and Rosaceae and Fabaceae (5% each) were the most cited families. The survey revealed that leaves were the most used parts of the plants (29%). Furthermore, decoction (35%), raw (24%), and infusion (19%) were the common modes for the remedies’ preparation. Here, 15% of the total species were newly reported as medicinal plants. Besides, it was reported for the first time a total of 47 new therapeutic uses for 20 known plant species. Of 17 ailments categories, cancer was presented by 44 species, showing the highest FIC of 0.46. Marrubium vulgare L., Artemisia herba-alba Asso., Zingiber officinale Roscoe., and Juniperus phoenicea L. recorded the maximum fidelity value of 100%. Therefore, our study reveals strong ethnomedicinal knowledge shared by local populations living in the three regions studied. The medicinal species with a high FL could be promising candidates for identifying new bioactive molecules.

scholarly journals Identification and documentation of Ethno-veterinary remedies used by Afar Pastoralists for the treatment of Camel diseases in Ethiopia

2021 ◽  
Author(s):  
Fikadu Gutema ◽  
Weldegebrial G.Aregawi ◽  
Juhar Tesfaye Bekele ◽  
Abel sorsa Geletu
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Animal Health ◽  
Traditional Healers ◽  
Herbal Remedies ◽  
Phytochemical Analysis ◽  
Ethnoveterinary Medicine ◽  
Plant Parts ◽  
Afar Region ◽  
Plant Nursery

Abstract Background: Ethnoveterinary medicine is a scientific term for traditional animal health care that encompasses knowledge, belief, practice and skill of the community used for curing diseases and maintaining health of animals. A cross-sectional study was conducted using semi-structured questionnaires from September 2016 to August 2017 to gather information on the knowledge, practice and skill of the pastoralists and traditional healers about the importance and application of Ethno-veterinary medicine. Moreover, this study was conducted with the objectives of identification and documentation of major ethno-veterinary medicinal plants commonly used to treat camel aliments in Afar region.Result: A total of 146 traditional healers and pastoralists were interviewed for baseline and reliable information about Ethno-veterinary medicinal practice in Afar region. Accordingly, 99.3% of the respondents were men in which 66.44% of them were in the age range of 45-60. Majorities (76.02%) of the information’s concerning EVM were obtained from the elders among which 84.93% responded that the overall EVM practice and status in pastoral society of Afar is decreasing. A total of 710 plant species supposed to have medicinal property were recommended by pastoralists to be used for the treatment of 49 different animal diseases. Among 64 plants specimen collected, Balanites aegyptia, Cissus rotundifolia (Forssk.) Vahl, Cadaba rotundifolia Forssk, Solanum sp, Acalypha indica L and Tamarix aphylla (L.) Karsts were the commonly used plant species with high fidelity value. Concerned with plant parts used, leaf (20.5%) was the most frequently used plant parts followed by root (19.4%), fruit (14.4%), seed (10.8%) and entire plant (8.8%). These herbal remedies were administered orally, nasally, ocular and topically.Conclusion: pastoralists and traditional healers in Afar region have immense indigenous knowledge and practices of treating sick animals which should be supported by scientific techniques for analyzing the active ingredients contained in each plant species and for evaluating the safety, efficacy and dosage of the commonly used medicinal plants. In addition, on station establishment of commonly used medicinal plant nursery for conservation purpose and to conduct in-depth phytochemical analysis is paramount important.

scholarly journals The diversity and ethnobotanical study of medicinal plants in the southern slope of Mount Merapi, Yogyakarta, Indonesia

2019 ◽  
Vol 20 (8) ◽  
Author(s):  
MAIZER SAID NAHDI ◽  
ARDYAN PRAMUDYA KURNIAWAN
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Local Knowledge ◽  
Quantitative Methods ◽  
Curcuma Longa ◽  
Structured Interview ◽  
Piper Betle ◽  
Ethnobotanical Study ◽  
Southern Slope ◽  
Importance Value

Abstract. Nahdi MS, Kurniawan AP. 2019. The diversity and ethnobotanical study of medicinal plants in the southern slope of Mount Merapi, Yogyakarta, Indonesia. Biodiversitas 20: 2279-2287. Medicinal plants have been widely used by local communities in Indonesia due to its effectiveness as medicine and its low cost. In addition, the scientific and technological development of medicinal plants has been developed rapidly. This research aims to conduct inventory of medicinal plants recorded in the ecosystem of the southern slope of Mount Merapi, Yogyakarta and to reveal the local knowledge on their uses and traditional healing method applied. We used a combination of qualitative and quantitative methods. The data of local knowledge on medicinal plants and traditional medical practices when using them were collected through in-depth and semi-structured interview with local informants selected through purposive and snowball sampling. The results showed that the abundance of medicinal plant species at the study area was very high during the rainy season, while during the dry season, some of the plant species were found in the yard and open land. A total of 82 species from 40 families were identified as medicinal plants and used by the community through various processing and for various medical treatments. The information was inherited from previous generations through counseling and training. The most favorable way to use medicinal plants was by consuming the leaf directly. Among all identified medicinal plants, betel leaves (Piper betle L) had the highest importance value (43.6%), followed by turmeric (Curcuma longa L) (38.5%), and soursop (Annona muricata L) (33.3%). Kelor (Moringa pterygosperma, Gaertn) had the most significant usage value (0,6), followed by lemongrass (Cymbopogon citratus (DC) Stapf) and ginger (Curcuma xanthorrhiza Roxb) with the same value (0.3). The medicinal plants had also co-benefits including to encourage communication as well as to building relationship among community members.

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