scholarly journals Aflatoxin in feedstuffs and raw milk in Republic of North Macedonia, occurrence and assessment

2021 ◽  
Vol 26 (6) ◽  
pp. 3015-3021
Author(s):  
DUSHICA SANTA ◽  
SONJA SRBINOVSKA ◽  
SREKJKO GJORGJIEVSKI ◽  
VIKTORIJA GRUEVSKA ◽  
FROSINA ARSOVSKA
Keyword(s):  
Climate Changes ◽  
Animal Feed ◽  
Adult Population ◽  
Hazard Index ◽  
Raw Milk ◽  
Aflatoxin M1 ◽  
Low Levels ◽  
Favorable Conditions ◽  
Significant Health ◽  
Raw Cow’S Milk

The main objective of this research is to estimate the situation of occurance of aflatoxins in feedstuffs and aflatoxin M1 raw cow`s milk in Republic of North Macedonia. Detected average concentrations of total aflatoxins in the examined period 2014-2017 were below legal prescribed level. Within the official monitoring programme in the country, 1718 samples of raw cow's milk have been analyzed during 2017 and 2018. Comparison of the data showed that the number of examined samples with values for aflatoxin M1 above the allowed limits, according to the regulation is in 2018 (10 samples) and 2017 (5 samples). Additionally, the calculation of exposure assessment of the human population in North Macedonia demonstrated that the exposure to AFM1 of the adult population in N. Macedonia for 2017 is 0.0563 ng/kg bw/daily, and for 2018 is 0.0824 ng/kg bw/daily. The calculated hazard index (HI) In both years, was lower than one, which means that there are no significant health risks for the consumers. It is important to have continuously low levels of aflatoxins in animal feed and nutrition, especially that the climate changes create more favorable conditions for the development of moulds of Aspergillus.

scholarly journals Occurrence and seasonal variation of aflatoxin M1 in raw cow milk collected from different regions of Algeria

2020 ◽  
Vol 13 (3) ◽  
pp. 433-439 ◽  
Author(s):  
Sarah Mohammedi-Ameur ◽  
Mohammedi Dahmane ◽  
Carlo Brera ◽  
Moustafa Kardjadj ◽  
Meriem Hind Ben-Mahdi
Keyword(s):  
Animal Feed ◽  
Control Program ◽  
Raw Milk ◽  
Aflatoxin Contamination ◽  
Cow Milk ◽  
Aflatoxin M1 ◽  
Enzyme Linked Immunosorbent Assay ◽  
Survey Period ◽  
Lactating Cows ◽  
The Usa

Background and Aim: Aflatoxins are metabolites of molds that exert potentially toxic effect on animals and humans. This study aimed to investigate the occurrence of aflatoxin M1 (AFM1) in raw cow milk collected during 1 year (2016-2017) from different regions of Algeria and risk factors associated with the contamination. Materials and Methods: During the survey period, 84 samples of raw milk were collected in three regions of Algeria (northeast, north center, and northwest) during four seasons. AFM1 levels were analyzed by competitive enzyme-linked immunosorbent assay. Results: AFM1 was detected in 39 (46.43%) samples (total mean concentration, 71.92 ng/L; range, 95.59-557.22 ng/L). However, the AFM1 levels exceeded the maximum tolerance limit set by the Food and Drug Administration in the USA (500 ng/L) in only 1 sample (1.19%). Statistical analysis revealed significant differences (p<0.005) between AFM1 levels in milk samples collected in the spring and autumn. The mean AFM1 levels in samples collected in the spring were significantly higher than those in samples collected in autumn. Conclusion: The survey indicates that farmers involved in milk production should be made aware of the adverse effects of aflatoxin contamination in animal feed. A systematic control program of supplementary feedstuff for lactating cows should be introduced by the public health authorities.

Occurrence of Aflatoxins in Peanuts, Milk, and Animal Feed in Trinidad

2007 ◽  
Vol 70 (3) ◽  
pp. 771-775 ◽  
Author(s):  
NKECHI OFFIAH ◽  
ABIODUN ADESIYUN
Keyword(s):  
Animal Feed ◽  
Peanut Butter ◽  
Raw Milk ◽  
Aflatoxin M1 ◽  
Public Health Importance ◽  
Dairy Farmers ◽  
Pasteurized Milk ◽  
Milk Samples ◽  
Radioimmunoassay Method ◽  
Feed Samples

The prevalence of aflatoxin B1 (AFB1) in 186 peanut products (140 peanuts, 32 peanut butter, and 14 nut cakes) from supermarkets, road vendors, and sale outlets, and 40 feed samples from dairy farmers was determined using the radioimmunoassay method (Charm II) test for aflatoxins. The frequency of aflatoxin M1 (AFM1) was also determined in 175 raw milk samples from milk collection centers and 37 pasteurized milk samples obtained from supermarkets and sale outlets. Overall, from a total of 438 samples tested, 18 (4.1%) were positive for aflatoxin comprising 5 (2.2%) of 226 peanut products and feeds positive for AFB1, and 13 (6.1%) of 212 milk samples positive for AFM1. All 186 peanuts and peanut products were negative (0.0%) for AFB1 while 5 (7.4%) of 40 dairy feed samples were positive. Of the 175 raw milk samples tested, 13 (7.4%) were contaminated with AFM1 while all pasteurized milk samples were negative. The detection of AFB1 in feed and AFM1 in milk is of public health importance considering the practice of raw milk consumption by the farmers and their families in the country.

scholarly journals Aflatoxins in Milk and Dairy Products: Occurrence and Exposure Assessment for the Serbian Population

2020 ◽  
Vol 10 (21) ◽  
pp. 7420
Author(s):  
Ilija Djekic ◽  
Jelena Petrovic ◽  
Milica Jovetic ◽  
Azra Redzepovic-Djordjevic ◽  
Milica Stulic ◽  
...  
Keyword(s):  
Exposure Assessment ◽  
Dairy Products ◽  
Adult Population ◽  
Daily Intake ◽  
Raw Milk ◽  
Climatic Conditions ◽  
Aflatoxin M1 ◽  
Weather Extremes ◽  
Recall Methods ◽  
Milk And Dairy Products

The main objective of this study was to assess the exposure associated with aflatoxin M1 (AFM1) of the adult population in Serbia from consumption of milk and dairy products. This assessment was performed using concentration values of AFM1 in raw milk (385 samples) and dairy products (556 samples) based on the analyses conducted in the period between 2015 and 2018. In parallel, a dairy products consumption survey was completed during 2018 based on ‘one-day’ and ‘seven-day’ recall methods. In order to estimate the intake of AFM1 from the consumption of dairy products for both recall methods, a Monte Carlo simulation was conducted. The study revealed that pasteurized milk and yogurt are dairy products mostly consumed by the Serbian adult population. Estimated daily intake of AFM1 was in the range of 62–74 × 10−3 ng/kg bw/day, depending on the recall methods and scenarios employed. Although the results show moderate exposure risks compared to similar studies worldwide, climatic conditions and weather extremes that have occurred recently may have negatively influenced the contamination of feed and, consequently, AFM1 contamination of milk. As a result, it is justifiable to promote continuous monitoring in feed and dairy supply chains in Serbia and provide an update of exposure assessment.

scholarly journals DETERMINATION OF AFLATOXIN M1 IN RAW MILK PRODUCE AT YOBE STATE UNIVERSITY FARM DAMATURU, NIGERIA

2020 ◽  
Vol 4 (3) ◽  
pp. 457-463
Author(s):  
S. Gide ◽  
B. Muhammed ◽  
G. H. Galal ◽  
A. A. Iliyah ◽  
I. M. Mabu ◽  
...  
Keyword(s):  
High Performance ◽  
Hazard Index ◽  
Goat Milk ◽  
Raw Milk ◽  
Cow Milk ◽  
Aflatoxin M1 ◽  
State University ◽  
Analytical Strategy ◽  
Mean Convergence ◽  
Sheep Milk

The study was carried out to determine the contamination of aflatoxin M1 (AFM1) in samples (n=66) of raw milk, from three distinctive animal species (cow, n = 30; goat, n = 20; sheep, n = 16) at Yobe State University farm Damaturu in 2018. The analytical strategy utilized was high-performance liquid chromatography (HPLC). Immunoaffinity columns were used to achieve clean–up step during HPLC and fluorometric determination. The outcomes demonstrated that 36 (54.54%) samples out of the 66 samples are debased with AFM1. The sullying rates of AFM1 in dairy animals, goat milk and sheep milk were 80.0%, 25.0% and 46.75% respectively. The mean concentration for the cow, goat and sheep milk was  0.1333µg/l, 0.0462µg/l and 0.0519µg/l respectively. The general mean convergence of AFM1 levels for positive samples from the three distinctive species was 0.0727 µg/l and there was no huge contrast (p = 0.3624) in fixation levels between the three species. The estimated intake (EDI) of AFM1 from consumption of cow milk products by teachers and the students was 0.00158g/kg b.w/day based on one-day recall methods, while hazard index was recorded to be 1.58 x10-4. The high levels of AFM1 concentration recorded in this study is an indication of contamination by the fungus during storage of feeds, this may have negative effects on the human and animal’s health since it’s proven to be carcinogenic, causes growth impairment and immune suppression. Measures should be enforced on the storage of feeds which will consequently decrease the odds of aflatoxin in milk of 

Estimation of Aflatoxin M1 Levels in Some Dairy Products Manufactured from Raw Milk Experimentally Inoculated with Toxin

2019 ◽  
Vol 43 (1) ◽  
pp. 50-58
Author(s):  
H. S. Alnaemi
Keyword(s):  
Dairy Products ◽  
Raw Milk ◽  
Aflatoxin M1 ◽  
Consumer Health ◽  
Goat’S Milk ◽  
White Cheese ◽  
Elisa Technique ◽  
Permissible Levels ◽  
Goat's Milk

     Fate of AflatoxinM1 in soft white cheese and its by-product (whey) and in yogurt locally made from raw sheep's and goat's milk experimentally inoculated with 0.05 and 0.5 µg/l AflatoxinM1 were investigated using ELISA technique. Results reported that AflatoxinM1 was concentrated in cheese at levels significantly higher than that recorded in the raw milk that used for its processing, with a significant decrease in AflatoxinM1 levels in its by-product (whey) comparable to the raw milk used in manufacturing at both inoculated levels. Yogurt produced from raw sheep's milk at second inoculated level exerted AflatoxinM1concentration significantly lower than that present in the milk. Significant differences in AflatoxinM1distribution in cheese and whey produced from sheep's milk comparable to their counterparts produced from goat's milk were recorded. Finally, results revealed the efficacious role of the various dairy manufacturing processes in AflatoxinM1 distribution and the necessity to issue of local legislations concerning the maximum permissible limits for AflatoxinM1 in milk in order to stay within the universal permissible levels for AflatoxinM1 in dairy products to provide greater protection for consumer health. 

scholarly journals Factors Associated with Clinician Adherence to USPSTF Diabetes Screening Recommendations

2021 ◽  
Vol 12 ◽  
pp. 215013272110165
Author(s):  
Elaine Seaton Banerjee ◽  
Kyle Shaak ◽  
Nicole Burgess ◽  
Melanie Johnson ◽  
Beth Careyva
Keyword(s):  
Gestational Diabetes ◽  
Adult Population ◽  
Correct Diagnosis ◽  
Retrospective Chart Review ◽  
Diabetes Screening ◽  
Factors Associated ◽  
The Us ◽  
History Of ◽  
Missed Diagnosis ◽  
Significant Health

Introduction/Objectives: Diabetes and prediabetes impact nearly half of the US adult population and are associated with significant health risks but may be underdiagnosed. Effective screening may improve diagnosis and give patients opportunity to manage their disease. The purpose of this study was to determine screening rates, identify characteristics predictive of screening, and evaluate correct diagnosis of diabetes and prediabetes. Methods: Retrospective chart review of 71 433 patients eligible for diabetes screening, defined by completing A1c test within the 3-year study period. Results: A total of 31.3% of eligible patients received diabetes screening. Factors associated with screening include older age, female sex, non-white race, Hispanic ethnicity, Medicare or Medicaid insurance, higher BMI, and having a medical comorbidity. History of prediabetes or gestational diabetes were the strongest predictors for diabetes screening, but history of gestational diabetes was under-documented. Of those screened, 10.4% had a result consistent with diabetes and 51.8% had a result consistent with prediabetes. However, 52.9% of these patients had a missed diagnosis. Conclusions: Findings of this study indicate the need for uniform coverage for diabetes screening for all insurances, increased documentation of gestational diabetes to improve screening for patients with this history, and improving accurate diagnosis after screening is completed.

Occurrence of aflatoxin M1 in raw milk in South Korea using an immunoaffinity column and liquid chromatography

Food Control ◽  
2009 ◽  
Vol 20 (2) ◽  
pp. 136-138 ◽  
Author(s):  
Ji Eun Lee ◽  
Byung-Man Kwak ◽  
Jang-Hyuk Ahn ◽  
Tae-Hong Jeon
Keyword(s):  
Liquid Chromatography ◽  
South Korea ◽  
Raw Milk ◽  
Aflatoxin M1 ◽  
Immunoaffinity Column

Determination of Aflatoxin M1 in Raw Milk by the ELISA Method in the Una-Sana Canton

2020 ◽  
pp. 260-267
Author(s):  
Huska Jukić ◽  
Samira Dedić ◽  
Miloš Rodić ◽  
Zlatko Jusufhodžić ◽  
Dinko Demirović
Keyword(s):  
Raw Milk ◽  
Aflatoxin M1 ◽  
Elisa Method

scholarly journals Mycotoxin Contamination in the Food Chain

2017 ◽  
Vol 26 (3) ◽  
pp. 115
Author(s):  
Eny Martindah ◽  
Sjamsul Bahri
Keyword(s):  
Food Chain ◽  
Animal Feed ◽  
Toxin Production ◽  
Aflatoxin M1 ◽  
Economic Losses ◽  
Mold Growth ◽  
Mould Growth ◽  
Mycotoxin Contamination ◽  
T2 Toxin

Mycotoxins contamination in animal feed is harmful to livestock and leads to residues, such as aflatoxin and its metabolites (aflatoxin M1, aflatoxicol, aflatoxin Q1 and aflatoxin P1) which are deposited in meat, milk, and eggs. The existence of mycotoxins has been widespread; and mycotoxin is the most important contaminant in the food chain because it has implications for human health. Mold growth and mycotoxin production mainly depend on the weather, such as warm temperatures (28-31°C) and high humidity (60-90%). Some types of mold can produce more than one type of mycotoxin and some mycotoxins can be produced by more than one species of fungi. Mycotoxins, especially aflatoxin, fumonisin, zearalenone, ochratoxin, deoxynivalenol, and T2 toxin present in feed and feedstuffs that have to be controlled. Mycotoxins are not only harmful to the health of consumers, but will also reduce the quality of the product that is contaminated, and cause economic losses. The risk of mycotoxin contamination in animal feed could be reduced by inhibiting the mould growth and toxin production, through crop rotation, using proper fungicides, and applying regulation of mycotoxins maximum limit in feed and food in order to prevent any danger to public health.

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