Biochemical Profiles of Various Fresh Extracts of Gnaphalium polycaulon Pers

Author(s):  
Shanmugapriya K. ◽  
T. Murugan ◽  
Thayumanavan Tha

Medicinal plants plays a significant role in the pharmaceutical industry. In present scenario, the need is to explore, identify and utilize this new medicinal plant on one hand and, on the other, to help conserve the existing but threatened species of rare medicinal plant.This present research work was carry out for the first time in South India to analyse and estimate the biochemical profiles of various extracts of fresh parts of Gnaphalium polycaulon pers., plant. The biochemical composition such as total carbohydrates, total proteins, total lipids, total phenols, cholesterol, total chlorophylls and reducing sugar, sterols were estimated using the standard procedure in fresh plant material.The biochemical analysis of Gnaphalium polycaulon plant showed the presence of various phytochemicals. The results of the present study supplement the usage of the studied plant which possesses several bioactive compounds and used as food and also as medicine.The results of present studies demonstrated that Gnaphalium polycaulon plant could be a sourceof valuable information and a guideline for the scientists, researchers in India and also all over the world

2021 ◽  
Vol 21 (no 1) ◽  
Author(s):  
Shiva Sharma ◽  
Durg V Rai ◽  
Manisha Rastogi

Rudraksha bead or Elaeocarpus ganitrus (Roxb.) is a reverent plant based therapeutic agent with spiritual and holistic importance in traditional system of medicine since time immemorial. While multifarious pharmacological properties of Rudraksha beads have been reported against a range of chronic disorders, evidences about its compositional characteristics are highly superficial. The present study aims to quantify the biochemical, phytochemicals, functional groups, and elemental characteristics of three, four, and five Mukhi Rudraksha (3MR, 4MR, and 5MR) beads. Biochemical analysis encompasses quantification of total carbohydrates, total proteins, and crude fat content. Phytochemical analysis was performed to quantify alkaloids, saponins, flavonoids, phenolics, anthocyanins, ascorbic acid, tannins, and terpenoids. Identification of functional groups was carried out through Fourier transform infrared (FTIR) spectrophotometer and UV spectrophotometer. Elemental analysis was performed using CHNSO analyzer. One Way ANOVA with Posthoc Multiple Tukeys test was used for statistical analysis. Significant differences were obtained in all the biochemical, phytochemicals, functional groups, and elemental components among 3MR, 4MR, and 5MR. Future studies are warranted to identify the active biomarkers in different Mukhi Rudraksha that will add new therapeutic candidates in the ever-growing number


2014 ◽  
Vol 3 (3) ◽  
pp. 218-225
Author(s):  
R. G. Somkuwar ◽  
M. A. Bhange ◽  
A. K. Upadhyay ◽  
S. D. Ramteke

SauvignonBlanc wine grape was characterized for their various morphological, physiological and biochemical parameters grafted on different rootstocks. Significant differences were recorded for all the parameters studied. The studies on vegetative parameters revealed that the rootstock influences the vegetative growth thereby increasing the photosynthetic activities of a vine. The highest photosynthesis rate was recorded in 140-Ru grafted vine followed by Fercal whereas the lowest in Salt Creek rootstock grafted vines.The rootstock influenced the changes in biochemical constituents in the grafted vine thereby helping the plant to store enough food material. Significant differences were recorded for total carbohydrates, proteins, total phenols and reducing sugar. The vines grafted on1103-Pshowed highest carbohydrates and starch followed by 140-Ru,while the least amount of carbohydrates were recorded in 110-R and Salt Creek grafted vines respectively.Among the different rootstock graft combinations, Fercal showed highest amount of reducing sugar, proteins and phenols, followed by 1103-P and SO4, however, the lowest amount of reducing sugar, proteins and phenols were recorded with 110-R grafted vines.The vines grafted on different rootstocks showed changes in nutrient uptake. Considering this, the physico-biochemical characterization of grafted vine may help to identify particularrootstocks combination that could influence a desired trait in commercial wine grape varieties after grafting.


Metals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1079
Author(s):  
Victor Ciribeni ◽  
Juan M. Menéndez-Aguado ◽  
Regina Bertero ◽  
Andrea Tello ◽  
Enzo Avellá ◽  
...  

As a continuation of a previous research work carried out to estimate the Bond work index (wi) by using a simulator based on the cumulative kinetic model (CKM), a deeper analysis was carried out to determine the link between the kinetic and energy parameters in the case of metalliferous and non-metallic ore samples. The results evidenced a relationship between the CKM kinetic parameter k and the grindability index gbp; and also with the wi, obtained following the standard procedure. An excellent correlation was obtained in both cases, posing the definition of alternative work index estimation tests with the advantages of more straightforward and quicker laboratory procedures.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Gangadhar Ch ◽  
S. Jana ◽  
Sankararao Majji ◽  
Prathyusha Kuncha ◽  
Fantin Irudaya Raj E. ◽  
...  

Purpose For the first time in a decade, a new form of pneumonia virus, coronavirus, COVID-19, appeared in Wuhan, China. To date, it has affected millions of people, killed thousands and resulted in thousands of deaths around the world. To stop the spread of this virus, isolate the infected people. Computed tomography (CT) imaging is very accurate in revealing the details of the lungs and allows oncologists to detect COVID. However, the analysis of CT scans, which can include hundreds of images, may cause delays in hospitals. The use of artificial intelligence (AI) in radiology could help to COVID-19-positive cancer in this manner is the main purpose of the work. Design/methodology/approach CT scans are a medical imaging procedure that gives a three-dimensional (3D) representation of the lungs for clinical purposes. The volumetric 3D data sets can be regarded as axial, coronal and transverse data sets. By using AI, we can diagnose the virus presence. Findings The paper discusses the use of an AI for COVID-19, and CT classification issue and vaccination details of COVID-19 have been detailed in this paper. Originality/value Originality of the work is, all the data can be collected genuinely and did research work doneown methodology.


Author(s):  
Abou-eisha A ◽  
Adel E El-din

Objective: The aim of this study was to investigate, for the first time, the possible in vivo genotoxic and carcinogenic activity associated with exposure to norgestrel (NGT) drug through employing the very recently established and adjusted genotoxic and tumorigenic methods in Drosophila melanogaster.Methods: Two in vivo genotoxic test systems were used; one detects the somatic mutation and recombination effects (somatic mutation and recombination test [SMART] wing-spot test) and the other detects the primary DNA damage (the comet test) in the body cells of D. melanogaster. On the other hand, the warts (wts)-based SMART assay is a vital genetic examination in Drosophila used to identify and characterize cancer potential of compounds.Results: Four experimental doses of NGT were used (ranging from 0.24 μM to 16 μM). NGT was found to be non-genotoxic at all tested concentrations even at the highest dose level 16 μM and failed to increase the frequency of tumors in the somatic cells of D. melanogaster.Conclusion: Our results strengthen the hypothesis that steroidal drugs might act through a non-genotoxic carcinogen mechanism where the carcinogenic properties occur by direct stimulation of cellular proliferation through a steroid receptor-mediated mechanism. In addition, the results obtained in this research work may contribute to highlighting the importance of NGT as a potent neuroprotective antioxidant drug.


2019 ◽  
Vol 52 (1) ◽  
pp. 54-65
Author(s):  
M.M. Rashid ◽  
H. Khatun ◽  
M.F. Rayhan ◽  
M.E.A. Plabon ◽  
M.U. Hossain ◽  
...  

Abstract Fruits and vegetables are important sources of nutrients for mankind. Among the various fruits available in Bangladesh, mango occupies a vital place in the human nutrition for its delicious taste and higher nutritious value. In this study, five mango varieties, viz. Fazli, Amrupali, Langra, Gopalbogh and Misribogh, were tested to evaluate the quality of these mango varieties available in Northern Bangladesh. Physiochemical characteristics, including moisture, ash, total carbohydrates, total solids, total soluble solids (TSS), pH, acidity, total sugars and ascorbic acid contents were evaluated. The results showed that there were significant (p< 0.05) differences among mangoes of all varieties for physicochemical parameters. In case of proximate composition, the mango variety Amrupali showed the highest ash content (2.34±0.15) and fat content (1.18±0.13). Protein content (0.94±0.12) and total fiber (2.67%) content was shown to be the highest by Gopalbogh and Misribogh, respectively. The selected mango varieties contained TSS of 12.87~20.55oBrix, pH of 4.45~4.67, titrable acidity of 0.07~0.42%, reducing sugar of 8.40~15.43%, non-reducing sugar of 9.24~10.48%, and total sugarof 18.88~25.12%. The study findings would be helpful for the consumers, dietitian and industry policymakers.


2021 ◽  
Author(s):  
Mainak Bhattacharya

A hundred years since the first mention of the word empathy in the English language, scientists and philosophers have been unable to arrive at a common consensus on its precise definition. Common wisdom associates empathy with vicarious emotional arousal or altruism. This study conducts a systematic review of research work in business studies dealing with empathy. The method used comprises applying lower-level abstract taxonomy to empathy, for the first time, in external business stakeholder interaction situations of sales, marketing, and customer service. The measurement scales used in the studies are analyzed to showcase mental processes at stake during the act of empathy, the theorized functions, and expected business outcomes of empathy. Implications are drawn for various aspects of managerial decision making. The study suggests a novel framework to execute a more nuanced grade examination of processes involved in empathy and reducing subjectivity in conceptual definitions. The study also calls for overhauling empathy measurement scales, mainly to suit adaptations in empirical business studies.


2015 ◽  
Vol 38 (2) ◽  
pp. 181-184
Author(s):  
V. Kumar

Crotalaria paniculata Willd. is reported for the first time from Kerala although it is commonly found in all the other three states of South India. Further, discussion is made about its questionable occurrence in Java (Indonesia) and opined here that it is endemic to South India. C. paniculata var. nagarjunakondensis Thoth. is raised to the specific level based on cordate cuspidate bract, absence of stipules, length of calyx teeth as well as 2-seeded pods.


1989 ◽  
Vol 44 (7-8) ◽  
pp. 597-608 ◽  
Author(s):  
Helen J. Stavrakakis ◽  
Sofia K. Mastronicolis

The total lipids of the commercial land snail Eobania vermiculata (Gastropoda, Pulm onata, Stylom m atophora) are found to constitute a small percentage (0.8% ) of the wet tissue, which is comparable to that reported for other gastropods. Polar lipid components comprise 61.4% of the total lipids. The individual lipid classes obtained by column chromatographic fractionation were purified by preparative TLC or by column chromatography and their structure was confirmed by a combination of chromatographic and analytical determinations before and after mild alkaline hydrolysis and/or (dry) acid methanolysis and by IR analysis. Neutral lipids represent 36.4% of total lipids, containing cholesterol, cholesterol esters and triglycerides as their major components (26.2% , 29.1% and 25.5% respectively). They contain also a significant amount (14%) of free glyceryl ethers, which are found in a mollusc for the first time. The overall composition of the polar lipids (mol/100 mol lipid-P) was found as follows: Cardiolipin, 2.9; phosphatidylethanolamine, 24.9 (of which 19.8% plasmalogen analog); phosphatidylcholine, 49.2 (of which 45.6% glycerylether analog); ceramide aminoethylphosphonate, 7.5 plus 0.01 (another three minor species); diglyceride-am noethylphosphonate, 6.3; Sphingoethanolamine 1.65 (for the first time found and structurally studied in a land gastropod); and phosphatidic acid 1.1. Unsaturated fatty acyl groups represent about 72.6 and 44.1 respectively in phosphatidylethanolamine and phosphatidylcholine. A significant amount (70.5% ) of unsaturated fatty acids is concentrated in neutral lipids. The C16:0 alk-1-enyl chain was found to predominate (55.6% ) in the side chains of ethanolamine plasmalogen. Batyl alcohol was found as the main glycerylether bound to choline phosphate (97.5% ). Saturated fatty acyl groups with 16 carbon atoms were main components (54%) of the major ceramide aminoethylphosphonate species.


2015 ◽  
Vol 73 (3) ◽  
pp. 897-909 ◽  
Author(s):  
J. Strahl ◽  
D. S. Francis ◽  
J. Doyle ◽  
C. Humphrey ◽  
K. E. Fabricius

AbstractAt two natural volcanic seeps in Papua New Guinea, the partial pressure of carbon dioxide (pCO2) in the seawater is consistent with projections for 2100. Here, the cover of massive scleractinian corals Porites spp. is twice as high at elevated compared with ambient pCO2, while that of branching corals such as Acropora millepora is greater than twofold reduced. To assess the underlying mechanisms for such community shifts under long-term exposure to elevated pCO2, biochemical parameters related to tissue biomass, energy storage, pigmentation, cell protection, and cell damage were compared between Porites spp. and A. millepora from control (mean pHtotal = 8.1, pCO2 = 323 µatm) and CO2 seep sites (mean pHtotal = 7.8, pCO2 = 803 µatm) each at two reefs. In Porites spp., only one of the biochemical parameters investigated (the ratio of photoprotective to light-harvesting pigments) responded to pCO2, while tissue biomass, total lipids, total proteins, and some pigments differed between the two reefs, possibly reflecting differences in food availability. Furthermore, some fatty acids showed pCO2 –reef interactions. In A. millepora, most pigments investigated were reduced at elevated pCO2, while other parameters (e.g. tissue biomass, total proteins, total lipids, protein carbonyls, some fatty acids and pigments) differed between reefs or showed pCO2–reef interactions. Tissue biomass, total lipids, and cell-protective capacities were distinctly higher in Porites spp. than in A. millepora, indicating higher resistance to environmental stress in massive Porites. However, our data suggest that important biochemical measures remain relatively unaffected in these two coral species in response to elevated pCO2 up to 800 µatm, with most responses being smaller than differences between species and locations, and also when compared with responses to other environmental stressors such as ocean warming.


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