Rheumatoid Arthritis: History, Stages, Epidemiology, Pathogenesis, Diagnosis and Treatment

Author(s):  
Abeer Fauzi Al-Rubaye ◽  
Mohanad Jawad Kadhim ◽  
Imad Hadi Hameed

The pharmacological mechanisms of the medicinal plants traditionally used for RA in Persian medicine are discussed in the current review. Further investigations are mandatory to focus on bioefficacy of these phytochemicals for finding novel natural drugs. Rheumatoid arthritis is chronic, progressive, disabling autoimmune disease characterized by systemic inflammation of joints, damaging cartilage and bone around the joints. It is a systemic disease which means that it can affect the whole body and internal organs such as lungs, heart and eyes. Although numbers of synthetic drugs are being used as standard treatment for rheumatoid arthritis but they have adverse effect that can compromise the therapeutic treatment. Unfortunately, there is still no effective known medicinal treatment that cures rheumatoid arthritis as the modern medicine can only treat the symptoms of this disease that means to relieve pain and inflammation of joints. It is possible to use the herbs and plants in various forms in order to relieve the pain and inflammation in the joints. There are so many medicinal plants that have shown anti rheumatoid arthritis properties. So the plants and plant product with significant advantages are used for the treatment of rheumatoid arthritis. The present review is focused on the medicinal plants having anti rheumatoid arthritis activity

2015 ◽  
Vol 21 (3) ◽  
pp. 228-234 ◽  
Author(s):  
Mahmoud Bahmani ◽  
Zohreh Eftekhari ◽  
Kourosh Saki ◽  
Ezatollah Fazeli-Moghadam ◽  
Mahyar Jelodari ◽  
...  

Obesity is an important disorders due to which 25 million deaths occur annually worldwide. Synthetic drugs for weight loss have low efficacy and high side effects. Apart from synthetic drugs in modern medicine, various other methods including the use of herbal medications are used to induce weight loss. Cambodia hoodia, green tea, Citrus aurantium, white beans, fenugreek, caffeine, ephedrine, capsaicin, yohimbine, chitosan, fitostreols, and guar gum have been studied in clinical trials and their effects have been confirmed. It seems necessary to study more to determine the effectiveness and safety of medicinal plants and herbal extracts as well as pharmaceutically active ingredients that may have the property of weight loss. In this article, we aimed to review recent knowledge about medicinal plants that are recommended for weight loss.


2019 ◽  
Vol 69 (4) ◽  
pp. 525-531 ◽  
Author(s):  
Željan Maleš ◽  
Daniela Ledić Drvar ◽  
Ivan Duka ◽  
Kristina Žužul

Abstract Treatment of skin conditions with medicinal plants has been an ongoing human activity lasting over thousands of years. The use of specific plant species developed regionally, based on local flora. Commonly used medicinal plants for dermatological complaints are: Phlebodium aureum (L.) J. Sm., Ginkgo biloba L., Rosmarinus officinalis L., Panax ginseng C.A.Mey., Allium cepa L., Aloe vera (L.) Burm.f., Capsicum annuum L., Berbe ris aquifolium Pursh, Camellia sinensis (L.) Kuntze, and Podophyllum peltatum L. The demand for complementary therapeutics is an emerging trend due to the awareness of potential side effects that synthetic drugs might cause. More scientific evidence and better documentation are needed before advising dermatologic patients on herbal medicinal treatment. Standardised extracts and formulations with proven clinical efficacy should be developed for this cause. Here provided review entails the use of herbal medicinal products in the treatment of frequent chronic skin diseases, such as vitiligo, alopecia, psoriasis and genital warts.


2016 ◽  
Vol 4 (6) ◽  
pp. 311-318
Author(s):  
Jyoti B. Wadekar ◽  
◽  
Ramesh L. Sawant ◽  
Unnati B. Patel ◽  
◽  
...  

Rheumatoid Arthritis (RA) is a chronic autoimmune disease of unknown aetiology that affects 0.5% of the population and can result in disability owing to joint destruction, characterized by joint synovial inflammation and progressive cartilage and bone destruction resulting in gradual immobility. The greatest disadvantage in the presently available potent synthetic drugs lies in their toxicity and reappearance of symptoms after discontinuation. With limitations of existing drug molecules herbal drugs are gaining interest among RA patients. Medicinal plants are plants containing inherent active ingredients used to cure disease or relieve symptoms of arthritis. The aim of this review is to update information on RA including causes, epidemiology, prevalence, symptoms and diagnosis, classification, medications, toxicities of allopathic anti-rheumatic drugs and importance of herbal drugs for the management of RA. The present review also focuses on the medicinal plants that interact with the mediators of inflammation and are used in the treatment of rheumatoid arthritis (RA).


Plants are used as a potential source of medicines since the prehistoric period. Medicinal plants are the richest bio-resource of drugs of a number of traditional systems of medicines. Medicinal plants can also be used as nutraceuticals, food supplements, folk medicines, pharmaceutical intermediates, and chemical entities for synthetic drugs. A good number of researches on medicinal plants have enriched the science of modern medicine over the last decades. Leea macrophylla (Leeaceae) locally known as ‘Hastikarna palasa’ is a shrub that has been used in herbal medicine as a cure for a number of disorders. Several studies have proven that the plant possesses potential antimicrobial, anti-oxidant, anti-inflammatory, analgesic, neuropharmacological and anti-diabetic activities. Tribal communities used the plant parts as a remedy for a number of ailments as well as nutritional products. Established in-vitro and in-vivo studies were conducted to get evidence of pharmacological activities of the plant parts. This review paper focuses on the phytopharmacological activities and traditional uses of the plant which may help further research activities on L. macrophylla by giving up-to-date information about the plant.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Raviraja Shetty G. ◽  
Harsha R.

Medicinal plants are considered as an effective source of traditional and modern medicine. In 20th and 21st century due to side effects of synthetic drugs, there is an increasing interest in Ayurvedic proprietary medicines. In India, about 80% of the rural population depends on medicinal herbs and/or indigenous system of medicine for primary health care. Adulterants and substitutes are the common malpractices in herbal raw material trade. Adulteration is considered as an intentional addition of foreign substances to increase the weight of the product or to decrease its cost. It may be due to Confusion in vernacular names, Lack of knowledge about authentic plants, Non availability, Similarity in morphology, activity, aroma, Careless collection and other unknown reasons. So, understanding of all the ways of adulteration and substitution is necessary to rectify this illegal act and maximizing consumer's safety.


2019 ◽  
Vol 2 (19) ◽  
pp. 11-18
Author(s):  
E. A. Korabelnikova ◽  
Al. B. Danilov

Therapy with medicinal herbs in the complex of therapeutic actions for insomnia occupies a special place. The main advantage of phytotherapy of sleep disorders is their high therapeutic efficacy in the absence of side effects, except in cases of individual sensitivity to individual components of the drug. Unlike synthetic drugs, drugs, which are based on vegetable raw materials, have a rapid effect on the extracellular and intracellular metabolic processes. Therefore, the therapeutic effect of medicinal plants is persistent and prolonged. The method of phytotherapy is an alternative and highly effective method of treatment of insomnia, and it should not reject, but significantly complement other methods of modern medicine.


Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
F Rahman ◽  
S Hossan ◽  
AH Mollik ◽  
R Jahan ◽  
M Rahmatullah

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
AH Mollik ◽  
S Hossan ◽  
T Islam ◽  
R Jahan ◽  
M Rahmatullah

2017 ◽  
pp. 122-127
Author(s):  
Thi Luu Nguyen ◽  
Thi Tan Nguyen

Objectives: To assess the effect of electronic acupuncture combined with “Tam ty thang” remedy in the treatment of rheumatoid arthritis by wind-cold-damp. Materials and methods: prospective study, comparing before and after treatment, including 43 patients who were diagnosed with rheumatoid arthritis by wind-cold-damp according to traditional medicine. Results: good level occupied 69,8%, and fair good level occupied 30,2%.The improved motor function accounted for 95.3%, to relieve pain up to 95,3%, reducing inflammation of VSS in 1 hour at the moment No 31,65, N28 17,88. The improvement in the level of activity of the hand reached 48,8% for good level. Conclusions: The method of electronic acupuncture combined with “Tam ty thang” remedy have a good effect in the treatment of rheumatoid arthritis by wind-cold-damp and it didn’t cause significantly side effects in clinic. Key words: rheumatoid arthritis, electronic acupuncture, “Tam ty thang” remedy


2019 ◽  
Vol 18 (2) ◽  
pp. 92-102 ◽  
Author(s):  
Fatma Tuğçe Gürağaç Dereli ◽  
Mert Ilhan ◽  
Esra Küpeli Akkol

Background & Objective: Depression, a risk factor for several serious diseases, is a highly prevalent and life-threatening psychiatric disorder. It can affect the individual’s position in life and reduce the living standards. The research on the use of medicinal plants in treating this disease has increased enormously because of the possible low rehabilitation rate and side effects of available synthetic drugs, such as sexual dysfunction, nausea, fatigue, insomnia, hypersomnia, and weight gain.Conclusion:Therefore, this review aimed to draw attention to the antidepressant effects of culinary herbs and traditional medicinal plants and their active components, thereby promoting their use in the development of more potent antidepressants with improved side effect profile.


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