scholarly journals Perfil epidemiológico da sífilis gestacional e congênita no Brasil – período de 2007 a 2016 / Epidemiological profile of gestational and congenital syphilis in Brazil – from 2007 to 2016

Author(s):  
Beatriz Raia Bottura ◽  
Laís Matuda ◽  
Priscila Simão Serrano Rodrigues ◽  
Cássia Maria Carvalho Abrantes do Amaral ◽  
Lene Garcia Barbosa

Objetivo: Descrever a ocorrência dos casos notificados de sífilis congênita e materna nas regiões do Brasil, considerando o perfil epidemiológico das mães. Métodos: Estudo transversal constituído pelos casos notificados de sífilis gestacional e congênita no Brasil, no período de 2007 a 2016. Os dados foram coletados no SINAN (Sistema de Informação de Agravos de Notificação). Resultados: Houve um aumento dos casos de sífilis gestacional e congênita, no período analisado. O perfil das gestantes com sífilis foi semelhante em todas as regiões do país, com idade 20 a 29 anos e ensino fundamental incompleto. O diagnóstico de sífilis gestacional foi predominantemente realizado durante o pré-natal e o de sífilis congênita no período neonatal. O pré-natal foi realizado em 80% dos casos. O tratamento inadequado da sífilis materna obteve valores extremamente baixos, devido ao não tratamento dos parceiros. Conclusão: Ao longo dos anos houve aumento do número de casos de sífilis gestacional e congênita evidenciando a necessidade de ações efetivas para tratamento correto e prevenção.Descritores: Sífilis congênita, Sífilis, Perfil de saúde, Prevalência, Doenças sexualmente transmissíveis, Estudos epidemiológicosABSTRACTObjective: To describe the occurrence of reported cases of congenital and maternal syphilis in Brazilian regions, considering the epidemiological profile of the mothers. Methods: A cross-sectional study of reported cases of gestational and congenital syphilis in Brazil, from 2007 to 2016. Data were collected at SINAN (Notification of Injury Information System). Results: There was an increase in gestational and congenital syphilis in the analyzed period. The profile of pregnant women with syphilis was similar in all regions of the country, aged 20 to 29 years and incomplete elementary school. The diagnosis of gestational syphilis was predominantly performed during prenatal and congenital syphilis in the neonatal period. Prenatal care was performed in 80% of the cases. The inadequate treatment of maternal syphilis obtained extremely low values due to the non-treatment of the partners. Conclusion: Over the years there was an increase in the number of cases of congenital and gestational syphilis evidencing the need for effective actions for correct treatment and prevention. Keywords: Syphilis, congenital; Syphilis, Health profile, Prevalence, Sexually transmitted diseases, Epidemiological studies

Author(s):  
Laryssa Cristina Alves da Silva ◽  
Bruno Batista Pereira da Paz ◽  
Matheus Santos Duarte ◽  
Carlos Dornels Freire de Souza ◽  
Túlio Romério Lopes Quirino ◽  
...  

<p><span class="fontstyle0">This article sought to describe the profile of congenital syphilis (CS) cases in Pernambuco and to evaluate government responses from 2008 to 2017. This is a cross-sectional study, with data obtained from the Department of Chronic Conditions and Sexually Transmitted Infections / MS. A trend analysis was conducted with the Joinpoint program and the following variables were adopted: maternal age group, maternal race / color, maternal education, moment of diagnosis of maternal syphilis, maternal treatment scheme, treatment of the mother’s partner and performance of prenatal. From 2008 to 2017, 9866 cases of congenital syphilis were registered in the state of Pernambuco, the numbers of cases showed an increasing trend over the time line. Out of the total, 75% (n = 7405) of women with a notified outcome of CS performed prenatal care. But only 36.9% (n = 3642) of cases of syphilis during pregnancy were diagnosed. As for the treatment performed, 57% (n = 6551) were done inappropriately. The data reflect the need for adjustments in prenatal care in Pernambuco, as well as the strengthening of actions aimed at controlling this indicator</span> <br /><br /></p>


2018 ◽  
Vol 7 (2) ◽  
pp. 236-248
Author(s):  
Luana Rosso ◽  
Mariá Vaz Franco Martins ◽  
Maria Tereza Soratto ◽  
Ivanir Prá da Silva Thomé ◽  
Rozilda Lopes de Souza

A sífilis é uma doença infecciosa sistêmica de evolução crônica e muitas vezes assintomática, transmitida principalmente por via sexual e vertical. O estudo em questão trata-se de um estudo de corte transversal, retrospectivo, descritivo de natureza quantitativa e documental, a coleta de dados se deu no Programa de Atenção Municipal as DST/HIV/AIDS (PAMDHA) do município de Criciúma, através de pesquisa documental com base nos dados da Vigilância Epidemiológico do SINAN com o objetivo de investigar os casos de sífilis congênita no município. Através da pesquisa pode-se perceber que entre os anos de 2015 e 2016 constatou 3,7% do total de casos pesquisados chegaram a óbito, dos RN nascidos com sífilis 51,9% foram assintomáticos e 3,8% sintomáticos, os demais não apresentaram características. Do total de gestantes, 66,6% realizou pré-natal e foram diagnosticadas a partir do mesmo, possibilitando o tratamento. Para que haja uma menor prevalência de casos de sífilis é necessário que os profissionais da saúde adotem, além das políticas públicas já disponíveis outros hábitos que levem ao alcance de todas as classes de gestantes, para evitar mais casos de sífilis.Palavras-chave: Gestantes. Sífilis Congênita. Recém-Nascidos. Infecções Sexualmente Transmissíveis. CONGENITAL SYPHILIS: AN ANALYSIS OF THE EPIDEMIOLOGICAL PROFILE IN THE CITY OF CRICIÚMA ABSTRACT: Syphilis is a systemic infectious disease of chronic evolution and often asymptomatic, transmitted mainly through sexual and vertical. The study in question it is a cross-sectional study, retrospective, descriptive quantitative and documentary nature, data collection took place in the Attention the Municipal STD/HIV/AIDS (PAMDHA) of the city of Criciúma, through documentary research based on Epidemiological Surveillance data from SINAN aiming to investigate the cases of congenital syphilis in the municipality. Through research you can notice that between the years 2015 and 2016 found 3.7% of total cases surveyed came to death, the RN born with syphilis 51.9% 3.8% were asymptomatic and symptomatic, the others did not show characteristics. Of the total of 66.6% pregnant women, prenatal and conducted were diagnosed from the same, allowing the treatment. So there is a lower prevalence of syphilis cases is necessary that health professionals adopt, in addition to the already available public policies other habits that lead to reach of all classes of pregnant women, to prevent more cases of syphilis.Keywords: Pregnant women. Congenital Syphilis. Newborns. Sexually Transmitted Infections.


2017 ◽  
Vol 49 (2) ◽  
pp. 322-342 ◽  
Author(s):  
Raquel Rodrigues dos Santos ◽  
Roberta Pereira Niquini ◽  
Francisco Inácio Bastos ◽  
Rosa Maria Soares Madeira Domingues

The study aimed to assess conformity with Brazil’s standard protocol for diagnostic and therapeutic practices in the management of congenital syphilis by pediatricians in public maternity hospitals. A cross-sectional study was conducted in 2015 with 41 pediatricians working in all the public maternity hospitals in Teresina, the capital of Piauí State, Northeast Brazil, through self-completed questionnaires. The study assessed the conformity of knowledge and practices according to the Brazilian Ministry of Health protocols. The study has made evident low access to training courses (54%) and insufficient knowledge of the case definition of congenital syphilis (42%) and rapid tests for syphilis (39%). Flaws were observed in the diagnostic workup and treatment of newborns. Requesting VDRL (88%) and correct treatment of neurosyphilis (88%) were the practices that showed the highest conformity with standard protocols. Low conformity with protocols leads to missed opportunities for identifying and adequately treating congenital syphilis. Based on the barriers identified in the study, better access to diagnostic and treatment protocols, improved recording on prenatal cards and hospital patient charts, availability of tests and medicines, and educational work with pregnant women should be urgently implemented, aiming to reverse the currently inadequate management of congenital syphilis and to curb its spread.


2019 ◽  
Vol 13 (3) ◽  
pp. 604
Author(s):  
Isadora Maria Delmiro Silva ◽  
Eliane Maria Medeiros Leal ◽  
Helder Freire Pacheco ◽  
José Gilmar de Souza Junior ◽  
Filipe Santana da Silva

RESUMOObjetivo: descrever o perfil epidemiológico dos casos de Sífilis Congênita (SC) notificados em um município nordestino. Método: trata-se de um estudo do tipo seccional, de caráter descritivo, de todos os casos de sífilis congênita notificados pelo Sistema de Informação de Agravos de Notificação (SINAN) e pelo Sistema de Informações sobre Nascidos Vivos (SINASC). Apresentam-se os resultados em forma de tabelas. Resultados: identificaram-se 57 casos, com taxa anual média de incidência de SC de 6,72 casos por mil nascidos vivos (NV), entre 2011-2015, variando de 11,20/1000 NV em 2012 a 3,77/1000 NV em 2015. Registrou-se no período uma diminuição de 7,4% nos casos, porém, ainda ultrapassando a meta do Ministério da Saúde de incidência menor ou igual a 1/1000 NV. Conclusão: aponta-se, pelo estudo, a necessidade de melhorias na qualidade da assistência pré-natal, pois, mesmo havendo a diminuição na incidência da SC, os indicadores mostram valores distantes da meta. Descritores: Sífilis Congênita; Nascimento Vivo; Nascimento; Gravidez; Perfil de Saúde; Vigilância; Epidemiologia.ABSTRACT Objective: to describe the epidemiological profile of Congenital Syphilis (CS) cases reported in a Northeastern municipality. Method: this is a cross-sectional study of all cases of congenital syphilis reported by the SINAN and the SINASC. The results are presented in the form of tables. Results: 57 cases were identified, with a mean annual incidence rate of SC of 6.72 cases per thousand live births (LB), between 2011-2015, ranging from 11.20 / 1000 LB in 2012 to 3.77 / 1000 LB in 2015. A reduction of 7.4% in cases was recorded in the period, however, still exceeding the target of the Ministry of Health of incidence less than or equal to 1/1000 LB. Conclusion: the study points to the need for improvements in the quality of prenatal care, since even though there is a decrease in the incidence of CS, the indicators show values that are distant from the goal. Descriptors: Congenital syphilis; Live Birth; Birth; Pregnancy; Health Profile; Surveillance; Epidemiology.RESUMENObjetivo: describir el perfil epidemiológico de los casos de Sífilis Congénita (SC) notificados en un municipio nordestino. Método: se trata de un estudio del tipo seccional, de carácter descriptivo, de todos los casos de sífilis congénita notificados por el Sistema de Información de Agravios de Notificación (SINAN) y por el Sistema de Información sobre Nacidos Vivos (SINASC). Se presentan los resultados en forma de tablas. Resultados: se identificaron 57 casos, con una tasa anual media de incidencia de SC de 6,72 casos por mil nacidos vivos (NV), entre 2011-2015, variando de 11,20 / 1000 NV en 2012 a 3,77 / 1000 NV en el año En el período se redujo un 7,4% en los casos, pero superando la meta del Ministerio de Salud de incidencia menor o igual a 1/1000 NV. Conclusión: se señala, por el estudio, la necesidad de mejoras en la calidad de la asistencia prenatal, pues, aun habiendo la disminución en la incidencia de la SC, los indicadores muestran valores distantes de la meta. Descriptores: Sífilis Congénita; Nacimiento Vivo; Nacimiento; Embarazo; Perfil de Salud; Vigilancia; Epidemiología.


2020 ◽  
Author(s):  
Ana Fatima Braga Rocha ◽  
Maria Alix Leite Araújo ◽  
Melanie M. Taylor ◽  
Edna O. Kara ◽  
Nathalie Jeanne Nicole Broutet

Abstract Background Between 2014 and 2016, Brazil experienced a severe shortage in penicillin supply, resulting in a lack of treatment among some pregnant women and newborns with syphilis and the use of non-evidence-based regimens. The aim of this study is to describe the different therapeutic regimens used in newborns with congenital syphilis during the period of penicillin shortage using a retrospective cross-sectional study design conducted in Fortaleza, Northeast Brazil. Methods Hospital medical records and case reporting forms of live births reported with congenital syphilis in 2015 and the associated maternal syphilis cases were reviewed during June 2017 to July 2018 from all public maternity hospitals in the city of Fortaleza. Results A total of 575 congenital syphilis cases were reported to the municipality of Fortaleza during 2015 and 469 (81.5%) were analyzed. Of these, only 210 (44.8%) were treated with a nationally-recommended treatment. As alternative therapeutic options, ceftriaxone was used in 65 (13.8%), Cefazolin in 15 (3.2%) and the combination of more than one drug in 179 (38.2%). Newborns with VDRL titers > 1:8 (p = 0.021), who had some clinical manifestation at birth (p = 0.003), who were born premature (p < 0.001), with low birth weight (p = 0.010), with jaundice indicative of the need for phototherapy (p = 0.019) and with hepatomegaly (p = 0.045) were more likely to be treated with penicillin according to national treatment guidelines compared to newborns treated with other regimens. Conclusion During the period of shortage of penicillin in Fortaleza, less than half of the infants with CS were treated with a nationally-recommended regimen, the remaining received treatment with medications available in the hospital of birth including drugs that are not part of nationally or internationally-recommended treatment recommendations.


2020 ◽  
Author(s):  
Xiaohui Zhang ◽  
PZ Zhao ◽  
WJ Ke ◽  
LY Wang ◽  
Lai Sze Tso ◽  
...  

Abstract Background: Mycoplasma genitalium (MG) causes urogenital tract infections and is associated with reproductive morbidity. Although MG has been reported across many regions and population groups, it is not yet routinely tested for in China. Our study contributes to current research by reporting the prevalence and correlates of MG infection in patients attending a sexually transmitted infection (STI) clinic in Guangdong from Jan 2017-May 2018.Methods: Urethral (from 489 men) and endo-cervical (from 189 women) samples, blood samples, and patient histories (via questionnaires) were collected. Doctors clinically diagnosed anogenital warts (GW) during the examination (n=678). The presence of MG was evaluated using an in-house via polymerase chain reaction protocol. We also tested all participants for herpes simplex virus-2 (HSV-2), Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), syphilis and HIV. Univariate and multivariate logistic regression were used to evaluate factors associated with MG.Results: MG was detected in 7.2% (49/678) of the patients (men, 7.4%; women, 6.9%). The MG positivity rate was 14.2% among symptomatic patients, and 5.6% for asymptomatic patients , respectively. Only 36.7% (18/49) Mg positive patients were symptomatic. Among the MG-infected patients, 10.2% were co-infected with CT, 6.1% with NG, 8.2% with HSV-2, 4.1% with syphilis and 22.4% with GW. Presentation with clinical symptoms was significantly associated with MG infection [OR=2.52 (2.03-3.13)]. In our analysis, MG was not associated with other STIs.Conclusions: MG is a relatively common infection among individuals attending an STI clinic in Guangdong Province. Routine testing of symptomatic patients may be necessary, and more epidemiological studies are needed to provide evidence for future testing guidelines,


Author(s):  
◽  

Objective: To analyze the epidemiological profile of congenital syphilis in the state of Alagoas from 2015 to 2019. Methods: Epidemiological study characterized as descriptive, observational, retrospective and cross-sectional, carried out based on data collected from the Information System for Notifiable Diseases (SINAN) and made available by the Department of Chronic Conditions and Sexually Transmitted Infections. Results and Discussions: When observing the cases of congenital syphilis, 2019 saw a significant drop in cases compared to the years 2015 to 2018. Conclusion: It is concluded that the epidemiological profile of DES demonstrates that the number of cases is higher among children under 7 days of age, the mother’s age range between 20 and 29 years, the mother’s education level from 5th to 8th grade incomplete and race / color of the mother, brown. This reflects for health professionals to seek more strategies to eradicate the disease in the state and in Brazil.


2021 ◽  
Vol 15 (10) ◽  
pp. 1462-1470
Author(s):  
Carolina Matteussi Lino ◽  
Maria da Luz Rosário de Sousa ◽  
Marília Jesus Batista

Introduction: Syphilis is an infectious disease of bacterial nature, acting on organs and/or systems. The increase in the number of cases worldwide has been of concern and the infection has been considered a public health problem. Given this scenario, this study evaluates the epidemiological profile, spatial distribution, and time series of the cases of acquired syphilis, syphilis in pregnant women, and congenital syphilis in a Brazilian municipality. Methodology: This is a cross-sectional and descriptive study with second data of the notified cases. For the definition of the population universe, an initial survey of syphilis cases notified in the municipality was carried out, from January 1, 2013 to December 31, 2017. Results: There was an increase in the notified cases and the detection/incidence rates of syphilis. The epidemiological profile was composed of men (76.7%), adults (24.8%), white (60.4%), with eight or more years of study (53.7%) in addition to pregnant adolescents (36.7%) and young adults (26.0%), with inadequate treatment and untreated partners. A concentration of cases was identified in the regions with the lowest monthly income and the time series showed an increasing trend (p-value < 0.001). Conclusions: Health actions should continue to improve access to diagnosis and to notification, focusing on treatment, cure and health education actions to control and prevent new cases.


2010 ◽  
Vol 4 (4) ◽  
pp. 1801 ◽  
Author(s):  
Shirley Suely Soares Veras Maciel ◽  
Wamberto Vieira Maciel ◽  
Maria Cristina Andrade ◽  
Claúdia Emanuella Oliveira Santana ◽  
Roselene Menezes Aleluia ◽  
...  

ABSTRACTObjective: to describe the patterns of Aids morbimortality in Caruaru, Pernambuco, Brazil, along the period of January, 2000 to December, 2006, Method: this is about a descriptive cross-sectional study. The data on morbidity and mortality were obtained from the Sistema de Informação de Agravos de Notificação (SINAN - Information System on Disease Notification) and the Sistema de Informações sobre Mortalidade (SIM - Mortality Information System) available at the Health Minister’s website, Results: of the total number of notified Aids cases (318 cases), 32.7% resulted in death. The reduction of the mortality rate is more meaningful among males than females; however the sex ratio was observed every year, excepting 2006. Conclusion: in Caruaru city, Aids affects more heterosexual young black male, with not more than 11 years of schooling. The results in death occurs more among young white male with no more than 3 years of schooling, Descriptors: acquired immunodeficiency syndrome; health profile; sexually transmitted diseases; information systems.RESUMOObjetivo: descrever o padrão de morbimortalidade por Aids em Caruaru- PE no período de janeiro de 2000 a dezembro de 2006, Método: trata-se de um estudo transversal descritivo. Os dados sobre morbidade e mortalidade foram obtidos a partir das bases de dados do Sistema de Informação de Agravos de Notificação (Sinan) e Sistema de Informação sobre Mortalidade (SIM) disponibilizados no site do Ministério da Saúde. Resultados: do total de casos notificados por Aids (318 casos), 32,7% evoluíram para óbito. A redução da taxa de mortalidade é mais expressiva no sexo masculino do que no feminino, todavia, a razão de masculinidade foi observada em todos os anos do estudo, excetuando-se em 2006, Conclusão: em Caruaru a Aids acomete mais pessoas jovens, pardas, do sexo masculino, com até 11 anos de estudo e heterossexuais, sendo que leva mais a óbito pessoas jovens, brancas, do sexo masculino e com até 3 anos de estudo, Descritores: síndrome de imunodeficiência adquirida; perfil de saúde; doenças sexualmente transmissíveis; sistemas de informação.RESUMENObjetivo: describir la tendencia de morbimortalidad por SIDA en Caruaru, Pernambuco, Brasil, desde enero de 2000 hasta diciembre de 2006, Método: se trata de un estudio transversal descriptivo. Los datos sobre morbidez y mortalidad se obtuvieron desde las bases de datos del Sistema de Información de Agravios de Notificación (SINAN) y del Sistema de Información sobre Mortalidad (SIM) disponibles en el sitio web  del Ministerio de la Salud. Resultados: del total de casos notificados de SIDA (318 casos), el 32,7% resultó en óbito. La reducción de la tasa de mortalidad es más significativa en hombres que en mujeres, sin embargo, la razón de masculinidad se observó en todos los años del estudio, con excepción del 2006. Conclusión: en Caruaru, el SIDA afecta más a las personas jóvenes, negras, de sexo masculino, con hasta 11 años de estudio y heterosexuales. Y los números de óbitos son más grandes entre las personas jóvenes, blancas, de sexo masculino y con hasta 3 años de estudio. Descriptores: síndrome de inmunodeficiencia adquirida; perfil de salud; enfermedades sexualmente transmisibles; sistemas de información. 


2021 ◽  
Vol 10 (36) ◽  
pp. 203-205
Author(s):  
Debora Alves dos Santos Fernandes ◽  
Francisco José de Freitas

Background: In 1966, the Gaffrée and Guinle University Hospital – GGUH was incorporated into the Federal University of the State of Rio de Janeiro – UNIRIO. Since then the Homeopathy clinic has had it's service there. Since the creation of medical residency in Homeopathy in 2004, there has been a significant increase of treatment in the number of patients and also a significant increase in the inter-relationship with other specialists and hospital services. A wide variety of patients have been treated at the GGUH on a daily basis. Many patients have been examined and treated with homeopathy alone, while others were also examined in other specialties, making homeopathic treatment an adjunct to classical therapy and vice versa. Given the expressive number of medical consultations (around 2500/year), this outstanding result in our clinical and academic practice has created the relevance and need for the verification of the epidemiological profile of these patients. Epidemiological studies are needed to clearly show the population included in this hospital, which is considered to be a reference in the Brazilian Health System (SUS). Aims: To demonstrate the epidemiological and clinical homeopathic profile in the ambulatory of homeopathy at the Gaffrée and Guinle University Hospital (GGUH) of the Federal University of the Staate of Rio de Janeiro - UNIRIO, Brazil. Methodology: Cross-sectional study of 140 medical records randomly selected from the ambulatory of homeopathy at GGUH. The sample represents 50% of the monthly average of the clinical service from January to October 2009. The medical records incorrectly completed for the data analysis were excluded. Microsoft Office Excel 2007 used to data collection and analysis. Results and Discussion: A total of 100 records were selected for analysis (71.4%). Average age: 50 years old, 69% being between 41 and 80 years old. Gender: 79% women and 21% men. Marital status: 46% married, 36% single, 10% divorced and 8% widowed. Color: 61% white, 31% colored and 8% black. Education: Only 12% obtained an undergratuadion degree. Groups of diseases: Group-01 (48%) high prevalence: 19% respiratory, 15% osteoarticular and 14% psychiatric; Group-02 (45%) medium prevalence: 11% gastrointestinal, 9% cardiovascular, 8% genitourinary, 6% neurological, 6% dermatologic and 5% endocrine; Group-03 (7%) low prevalence: 3% otological, 2% immunological, 1% oncological and 1% ophtalmological. 82% of the patients were treated solely with homeopathy and 18% with homeopathy and allopathy. Clinical-homeopathic diagnosis: 53% functional, 38% lesional; 9% sensorial. Constitutional diagnoses: 31% sulfuric, 25% phosphoric, 22% carbonic, 22% mixed. Miasmatic / diathesic diagnosis: 47% sycotic, 28% psoric, 12.5% mixed, 9.5% tuberculinic, 3% syphilinic. Conclusion: This study demonstrated a higher prevalence of women over 50 years old with respiratory, osteoarticular and psychiatric diseases. Most of them had a sulfuric constitution and presented functional diseases of sycotic origin. Homeopathy was the most adopted treatment during the period studied. This knowledge led to the creation of the “Homeopathic Clinical Identification Summary” which is used in the GGUH ambulatory. Epidemiological and clinical data were extracted from this summary with the objective to construct clinical trials.


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