scholarly journals Hypertensive crisis as cerebrovascular disease risk factor

2018 ◽  
Vol 15 (2) ◽  
pp. 60-64 ◽  
Author(s):  
M A Kravchenko ◽  
O S Andreeva ◽  
E V Gnedovskaya ◽  
A O Chechetkin ◽  
Yu Ya Varakin ◽  
...  

Objective. To assess main epidemiological indicators for hypertensive crises (HC) in the population of productive age and to study possible correlations of crisis associated arterial hypertension (AH) with clinical and instrumental phenomenon of chronic cerebrovascular diseases. Materials and methods. Data of several studies presented: cross-sectional studies of 726 people aged 35-64 and 415 people aged 40-59. Observational cohort study of 109 patients aged 57.4±5.8 with uncomplicated AH. For the detection of HC in anamnesis, there were used special criteria which widens standard HC definition for additional account of light and mild severity cases. Results. Overall AH prevalence was 45% (95% CI 41-51), in men - 48% (40.2-55.9), in women - 45% (38.4-51.6). History of HC in anamnesis was 11.8% (95% CI 9-15.2), in men 8.8% (5.4-14) and in women - 13.8% (10-18.7). Proportion of HC associated AH defined at the level of 25-30% of all AH cases. The most prevalence of HC associated AH was found in people with “high normal” (130-139/85-89) arterial pressure - 37%. Prevalence of the complaints on headaches, dizziness, poor memory and lower intellectual productivity was higher in people with HC. Chronic cerebrovascular disease was found 2-fold frequently in HC associated AH. But in generally analysis of possible correlations of HC with clinical and instrumental phenomenon of chronic cerebrovascular diseases didn’t revealed any statistically significant differences. Conclusion. HC burden for healthcare system is serious, because it is important risk factor for cerebrovascular diseases and associated with significant lowering of the quality of life. Prevalence of the HC cases with light and mild severity is underestimated. Despite that the study of the most prevalent forms of HC (rare, light and mild severity) didn’t find any associations with morphological or persistent clinical pathology, functional phenomenon were found statistically significant frequently.

Pulse ◽  
2016 ◽  
Vol 4 (1) ◽  
pp. 24-27 ◽  
Author(s):  
Thomas T. van Sloten ◽  
Coen D.A. Stehouwer

2014 ◽  
Vol 16 (4) ◽  
pp. e106
Author(s):  
Justin B Dickerson ◽  
Catherine J McNeal ◽  
Ginger Tsai ◽  
Cathleen M Rivera ◽  
Matthew Lee Smith ◽  
...  

1970 ◽  
Vol 9 (3) ◽  
pp. 143-149
Author(s):  
S Parvin ◽  
MM Hoque ◽  
N Sultana ◽  
Z Naoshin

Background: Non-HDL cholesterol is a potential newer risk factor for cerebrovascular diseases (CVD). Objective: To explore the association of non-HDL cholesterol with cerebrovascular disease. Methods: This case control study was carried out in the Department of Biochemistry, BSMMU, Dhaka during the period of January to December 2007 to evaluate the association of non-HDL cholesterol with CVD in Bangladeshi population. A total number of 135 subjects of both sexes were grouped as Group-I (CVD cases) and Group-II (Healthy controls). Group-I include 85 cases of which 59 were ischaemic cerebrovascular diseases (ICVD) and 26 were haemorrhagic cerebrovascular diseases (HCVD). By taking the history and doing clinical examination and laboratory investigations, diabetes mellitus, malignant disease, renal disease, liver disease and diuretic medication were excluded from study subjects. Serum non-HDL cholesterol was measured in all study subjects. Statistical analysis was performed by using SPSS for windows version 12.0. Mean values of the findings were compared between groups. One way ANOVA test and multiple comparison (Bonferroni‘t’) test were used to see the level of significance. Results: Serum non-HDL cholesterol found significantly increased in CVD, ICVD and HCVD cases in comparison to control subjects. But ICVD and HCVD cases did not differ with respect to serum non-HDLcholesterol. Conclusion: The result shows that elevated non-HDL cholesterol is associated with CVD. Prospective study with large sample size is required to evaluate the elevated Non-HDL cholesterol as a risk factor of CVD. Key words: Non-HDL cholesterol; Cerebrovascular disease; Ischaemic cerebrovascular disease; Haemorrhagic cerebrovascular disease. DOI: 10.3329/bjms.v9i3.6469Bangladesh Journal of Medical Science Vol.09 No.3 July 2010, pp.143-149


2020 ◽  
Vol 30 (4) ◽  
Author(s):  
Woro Riyadina ◽  
Ekowati Rahajeng ◽  
Srilaning Driyah

One of the adverse effect of prolonged patients with diabetes mellitus (DM), coronary heart disease (CHD), and stroke was the emerge of chronic kidney disease (CKD) and it would be burden of the economic. The prognosis of CKD in new cases of DM, CHD, and stroke during followed up in Cohort Study Noncommunicable Disease Risk Factor in Bogor was not yet known. Aim to study was to obtain to CKD profile in DM, CHD, stroke, and comorbid incidences during Cohort Study Noncommunicable Disease Risk Factor. This article has been result of cross sectional further analysis of secondary data on 370 new cases of DM, CHD, and stroke that who were examined for blood creatinine levels and calculated eGFR on 2018 and 2019. DM was diagnosed from fasting glucose ≥126 mg/dl or post prandial glucose ≥200mg/dl. CHD was diagnosed by ECG examination and validated by cardiologist and stroke was diagnosed by anamnesis by a neurologist. The main variable is eGFR as an indicator of CKD which is the result of CKP-epi calculation based on creatinine levels in the blood. Other variables are age, sex, type of disease (DM, CHD, and stroke). Data were analyzed using chi-square test. The results showed that average age patients with CKD on new cases of DM, CHD, stroke, and comorbid in Bogor were 48.2 ± 8.6 years old. Proportions CKD on new cases of DM, CHD, strok and comorbid were 59.5%, 56.7%, 66.7% and 50.0%. CKD was higher in older woman than others. The prevalence of CKD was found very high in subjects with stroke, DM, CHD, and comorbid. So, it is necessary to prevent complications by early diagnosis of NCD with regular monitoring of kidney function by creatinine level test and avoid using drugs that caused kidney damage. Abstrak Salah satu komplikasi buruk dari penderita diabetes melitus (DM), penyakit jantung koroner (PJK), dan strok yang berkepanjangan adalah munculnya gangguan fungsi ginjal dan akan membebani ekonomi bagi penderitanya. Gambaran prognosis gangguan fungsi ginjal pada insiden DM, PJK, dan strok selama pemantauan Studi Kohor Faktor Risiko PTM (FRPTM) Bogor belum diketahui. Tujuan penelitian untuk mendapatkan gambaran gangguan fungsi ginjal pada kasus baru DM, PJK, dan strok yang muncul selama pemantauan Studi Kohor FRPTM. Artikel ini merupakan hasil analisis lanjut secara potong lintang dari data sekunder kasus baru (insiden) DM, PJK, dan strok pada Studi Kohor FRPTM sebanyak 370 subjek yang diperiksa kadar kreatinin darah dan dihitung eLFG pada tahun 2018 dan 2019. DM didiagnosis dari kadar gula darah puasa ≥126 mg/dl atau post prandial ≥200mg/dl. PJK dari hasil pemeriksaan EKG dan validasi dokter spesialis jantung dan strok hasil anamnesis oleh spesialis saraf dan sudah mengalami rawat jalan. Variabel utama adalah eLFG merupakan indikator terjadinya gangguan fungsi ginjal yang merupakan hasil hitung kadar kreatinin dalam darah dengan CKD-epi. Variabel lain adalah umur, jenis kelamin, jenis penyakit (DM, PJK, dan strok). Data dianalisis dengan uji chi-square. Hasil menunjukkan temuan gangguan fungsi ginjal pada penderita DM, PJK, strok, dan komorbid di Bogor berumur 48,2 ± 8,6 tahun dan proporsi masing-masing 59,5%, 56,7%, 66,7%, dan 50%. Subjek yang mengalami gangguan fungsi ginjal menunjukkan lebih banyak pada umur lebih tua dan perempuan. Tingginya proporsi gangguan fungsi ginjal pada penderita strok, DM, PJK, dan komorbid diperlukan pencegahan komplikasi sejak awal terdiagnosis PTM dengan memantau fungsi ginjal dengan pemeriksaan kadar kreatinin secara teratur, serta menghindari penggunaan obat yang menimbulkan kerusakan ginjal.


Author(s):  
Garreth R. Dutton ◽  
Belinda L. Needham

Cross-sectional and longitudinal studies indicate a positive association between obesity and depression. While some evidence suggests that depression is a risk factor for obesity, other findings indicate that obesity is a risk factor for depression. Therefore the directionality of this relationship remains unclear. Alternatively, there may be common mediating biological or environmental contributors accounting for this association. Potential biological mediators include dysregulation of the HPA axis, leptin resistance, and inflammatory immune responses. Environmental and psychological mediators may include a history of abuse and binge eating. It is also possible that the association between obesity and depression is most pronounced among particular subsets of individuals (e.g., women, those with more severe obesity). A better understanding of this depression-obesity association is needed to guide treatment recommendations for obese clients with comorbid depression. Future research is also needed to determine who is most vulnerable to experiencing comorbid depression and obesity.


2018 ◽  
Vol 16 (3) ◽  
pp. 307-312
Author(s):  
Dipendra Kumar Yadav ◽  
Bhoopendra Sharma ◽  
Naveen Shrestha ◽  
Isha Karmacharya ◽  
Saroj Yadav

Background: The main aim of this study is to determine the prevalence of major Non communicable disease risk factors among higher secondary school students.Methods: A cross-sectional study was conducted among higher secondary students of grade 11 and 12 of Kaski district in Nepal. The study period was from July 2016 to June 2017. Total sample 640 higher secondary students were recruited through two-stage cluster sampling. Self-administrated questionnaire was used for the data collection tool along with other tools which were used such as UNICEF electronic weighing scale, stature meter and mechanical aneroid sphygmomanometer. Ethical approval was obtained from IRC, Pokhara University. Data were entered into EpiData software and analysis was performed with the help of the Statistical Package for Social Science (SPSS).Results:  The prevalence of smoking was 6.1% which was high in male (11.9%) than female (0.6%). Alcohol consumption practice among the adolescents was 18.9%. Family history of hypertension was seen higher than family history of diabetes.The prevalence of hypertension was 11.7%.High prevalence of abnormal values of systolic and diastolic BP was found in male than female students. Overweight was seen in 6.1% students. Prevalence of obesity was almost equal in both groups.Conclusions: There is high prevalence of smoking, alcoholism among adolescents. Hypertension was more common than diabetes among adolescents.


2018 ◽  
Vol 69 (10) ◽  
pp. 2652-2654
Author(s):  
Alina Ormenisan ◽  
Alexandra Balmos ◽  
Mihai Vlad Golu ◽  
Despina Bereczki Temistocle ◽  
Alina Baldean ◽  
...  

Obesity, a common metabolic disorder, is a condition for the development of chronic diseases, such as hypertension, diabetes mellitus, cardiovascular and cerebrovascular diseases. The present study evaluates the prevalence of periodontal diseases in Romania and their association with obesity, as a risk factor. This cross-sectional study included 170 subjects aged between 18-65, with healthy periodontal status, gingivitis, aggressive periodontitis and chronic periodontitis. All subjects completed the questionnaire with independent variables: age, education, socio-economic status, oral hygiene habits, smoking habit, the presence of any systemic diseases. Periodontal examination included: plaque index, gingival index, probing depth, clinical attachment level. Body mass index (BMI) and waist circumference (WC) were measured. Statistically significant correlations were found between periodontal diseases and BMI and WC: according to BMI 30.5% were obese, and 42.5% had high WC. 51.9% of obese participants had chronic periodontitis. Gingivitis and initial periodontitis do not influence BMI and WC, only the chronic periodontitis remained significantly associated with obesity. Our study suggests that there is an association between chronic periodontitis and BMI- defined obesity or WC, but further prospective studies should be carried on to establish the extent of it. The prevention and management of obesity may represent an approach to control periodontal health. Our study evaluates the prevalence of periodontal diseases in Romania and their association with obesity, as a risk factor.


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