scholarly journals Elemental state of the organism of workers and population as manifestation of adaptation to the technogenic effect of metals: new methodological approaches

2021 ◽  
Vol 26 (4) ◽  
pp. 174-180
Author(s):  
I.М.  Andrusyshyna
Keyword(s):  
Diabetes Mellitus ◽  
Heavy Metals ◽  
Human Body ◽  
Autoimmune Thyroiditis ◽  
Chemical Elements ◽  
Physiological State ◽  
Endocrine System ◽  
Type Ii Diabetes Mellitus ◽  
The Body ◽  
Professional Contact

The problem of adaptive, prepathological and pathological reactions of the body to the action of exogenous chemicals is closely intersected with the assessment of the norm and its fluctuations. The imbalance of chemical elements in the human body directly affects the functioning of almost all organs and systems, causing significant stress of adaptation mechanisms. In this article we study the elemental state of the human body depending on the physiological state (endocrine pathology and professional contact with heavy metals), analyze the correlation between macro- and microelements and assess the degree of adaptability of the body. In the work the elemental state of the human body, taking into account not only the absolute values of the concentrations of elements in the hair and whole blood was studied, the adaptability of the body according to the indicators of elemental imbalance in the blood and hair of volunteers, individuals with endocrine pathology (autoimmune thyroiditis and type II diabetes mellitus) and for those working in conditions of contact with heavy metals (for jewelers, welders and batterymen) is analyzed. The results of the study indicate that various non-specific adaptation reactions are accompanied by changes in the elemental state of a person. Under the prevailing pathology of the endocrine system (diabetes mellitus or autoimmune thyroiditis), the adaptation of the body was determined as a stage of tension and is associated with the duration of the disease. In persons exposed to professional contact with heavy metals (Mn, Cr, Pb, Ag), adaptation depended on the nature and duration of professional contact with them: the highest tension of adaptation processes was found in jewelers, and the least in welders and batterymen, which is associated with the duration of professional contact with these metals. The high number of connections between the elements indicates the tension of adaptive reactions in people with endocrine pathology and especially in jewelry workers. Adaptation to the high content of metals in the air of welders and batteries due to the longer experience of these workers and adaptation to production conditions with a decrease in the number of correlations between the elements, as a means of reliable operation.

scholarly journals Some Considerations Regarding the Presence of Heavy Metals in Soil and the Human Body

2020 ◽  
pp. 39-46
Author(s):  
Simona Anițaș ◽  
Mirela Coman ◽  
Bogdan-Vasile Cioruța
Keyword(s):  
Heavy Metals ◽  
Environmental Factors ◽  
Human Body ◽  
Chemical Elements ◽  
The Body ◽  
Earth’S Crust ◽  
Strong Impact ◽  
Trophic Networks ◽  
Trophic Chains ◽  
Earth's Crust

Until now, there have been laborious researches regarding the presence of heavy metals in environmental factors but their effects have been studied less in the bio-geo-chemical circuits, respectively within the local trophic chains and the regional trophic networks. Naturally, the metals existing in the earth's crust enter the bio-geo-chemical cycles. In the cells of higher organisms, as we know, there is a fragile balance between the amounts of metals needed for catalytic processes and toxic doses to organisms. However, this balance is dependent not only on the concentration and variety of metals in the Earth's crust but also on the microbiological activity of environmental factors, responsible for the transformation of these metals into complex chemical substances that affect more or less the organisms, respectively their enzymatic activity. The vital-necessary, but also the non-vital mineral substances in their mobile forms, which may at one time be toxic to organisms, are significantly pushed out by anthropic activities into trophic chains. They are present in environmental factors such as soil, air, water, reach the body of plants and the body of animals. Plants and animals can bioaccumulate and concentrate in their bodies several chemical elements in the environment, regardless of their origin, which is then easily transferred through food circuits into the human body. Thus, through local trophic chains, respectively through regional trophic networks, contamination of the human body takes place. This requires the need for a measure of most likely high complexity to mitigate the effects with a strong impact on the health status, including that of the human psychic. In severe cases of contamination, behavioral manifestations, especially among the vulnerable population, are proven.

scholarly journals EFEKTIVITAS KERASIONALAN PEMBERIAN ANTIDIABETIK PENGOBATAN ORAL PASIEN DIABETES MELLITUS PADA USIA 30-50 TAHUN TIPE 2 DI RAWAT INAP PENYAKIT DALAM RSUD DELI SERDANG LUBUK PAKAM TAHUN 2020

2021 ◽  
Vol 3 (2) ◽  
pp. 74-80
Author(s):  
Loraetta Brety Sebayang ◽  
Romauli Anna Teresia Marbun ◽  
Dewi Kartika
Keyword(s):  
Diabetes Mellitus ◽  
Oral Treatment ◽  
Type Ii Diabetes Mellitus ◽  
The Body ◽  
Quality Assurance Process ◽  
Experimental Type ◽  
Treatment Of Diabetes ◽  
Assurance Process ◽  
The Right

Background: Diabetes Mellitus is a chronic condition, which occurs because the body cannot produce insulin, normally or insulin cannot work effectively. Objective: To determine the effectiveness of the rational administration of antidiabetic, oral treatment of diabetes mellitus patients at the age of 30-50 years type 2 in Deli Serdang Hospital, lubuk pakam in 2020. Method: This study is a non-experimental type of research using descriptive methods. Results: Shows that from 72 samples of Type II Diabetes Mellitus patients at Deli Serdang General Hospital, April-July Period 2020. With the number (52.8%) of male sex patients and the number (47.2%) of type patients  female genitalia and antidiabetic drugs most widely used by patients, in the period of April-July 2020, namely (20.8%) glycionion + metformin and (20.8%) insulin drugs.  the use of DM drugs with the right rational indication (65.3%), Rational with the right medicine (100%), rational with the right dosage (100%), the right rational patient (100%) and the rational way of administration (100:%). Conclusion: Evaluation of drug use is a structured quality assurance process that is carried out continuously to ensure that the drugs used are appropriate, safe, and efficient.

Establishing the limits of the permissible content of chemical elements in the wool of representatives of the family Hamster Cricetidae using centile scales

2020 ◽  
Vol 1 (9) ◽  
pp. 72-77
Author(s):  
M. V. Stepanova ◽  
◽  
V. A. Ostapenko ◽  
Keyword(s):  
Heavy Metals ◽  
Copper Content ◽  
Chemical Elements ◽  
Federal District ◽  
The Body ◽  
Average Content ◽  
Absorption Method ◽  
Opposite Trend ◽  
The Family ◽  
Heavy Metals And Arsenic

The aim of the study was to study the content of some heavy metals and arsenic in members of the Cricetidae family of hamsters and to develop centile scales for assessing the level of accumulation of these elements for the Central Federal District. In 2018–2020, hamster`s wool was studied for the accumulation of zinc, copper, iron, lead, cadmium and arsenic by the atomic absorption method. The data on the characteristics of the content of chemical elements in different sexes of animals are given. In the course of the study, it was found that, according to the value of the average content in the wool of animals of the family, the studied elements form the following decreasing series: Fe> Zn> Pb> Cu> Cd> As. When studying the features of the accumulation of chemical elements by different sexes, a significant increase in the concentration of zinc, iron, cadmium and arsenic in the wool of males was established, compared with females, depending on the species, from 1,38 to 3,98; from 1,28 to 1,52; from 2,00 to 304,00 times, respectively. With regard to the accumulation of copper in the body, the opposite trend is observed. In females, its concentration is 1,5–3,19 times higher. In the studied sample of animals, an increase in copper content was revealed in 44,83% of individuals and a decrease in cadmium in 44,82%.

The Research Progress of Heavy Metals in PM2.5

2014 ◽  
Vol 955-959 ◽  
pp. 1397-1404 ◽  
Author(s):  
Li Na Shi ◽  
Xun Xu ◽  
Xiao Yan Dou ◽  
Xu Dong Zhao
Keyword(s):  
Heavy Metals ◽  
Air Pollution ◽  
Human Health ◽  
Human Body ◽  
Chemical Form ◽  
The Body ◽  
Detection Methods ◽  
Research Progress ◽  
Depth Study

PM2.5 is one of the most important components in air pollution. It is also the focus of the most closely watched at home and abroad. Based on its small size, complex components, and strongenvironmental activity, it can be used as a carrier for chemicals, heavy metals, bacteria, toxins and carcinogens into the body. Then, as a result, it will affect Human Body Health. Heavy metals are important components of PM2.5, and the long-term accumulation of heavy metals in PM2.5 poses a great threat on human health and the environment. This paper reviewed the sources, distribution methods,chemical form, detection methods, disposal way, research progress of heavy metals in PM2.5. As a result, it provided a reference for in-depth study on the future.

scholarly journals Gangguan Kesehatan Akibat Pencemaran Merkuri (Hg) pada Penambangan Emas Ilegal

2021 ◽  
Vol 12 (1) ◽  
pp. 8-15
Author(s):  
Masruddin Masruddin ◽  
Surahma Asti Mulasari
Keyword(s):  
Heavy Metals ◽  
Direct Contact ◽  
Gold Mining ◽  
Chemical Elements ◽  
Weather Conditions ◽  
Acute Poisoning ◽  
The Body ◽  
Cold Weather ◽  
Analysis Of Results ◽  
Hands And Feet

Gold mining activities can increase people's income and be detrimental if the correct processing process does not follow the implementation. This illegal gold mining and processing of gold ore use mercury. In the gold laundering process, who should carry out mercury with the correct procedures and knowledge. Still, in this illegal gold mining, the miners wash gold using mercury without using personal protective equipment so that the miners are in direct contact with the mercury used. Continuous, direct contact with heavy metals can cause an increase in chemical elements in the body caused by the bioaccumulation system. The purpose of this literature review is to determine the health problems caused by heavy metals in illegal gold mining. The database searches used are Garuda Portal and Google Scholar. There were 24 articles, and only ten were used, which were suitable through analysis of objectives, suitability of topics, analysis of results, and research locations. Based on the results of studies conducted, miners suffer from chronic and acute diseases. Chronic diseases suffered are liver dysfunction, decreased leukocytes, paralysis of limbs, numbness, and tremors. Symptoms felt by Parkinson's disease are constantly shaking hands and feet, facial muscles always moving involuntarily. Lips move unconsciously, lack passion for activities, difficulty sleeping, sometimes peaking emotions, poor memory, cramps during cold weather conditions, and often feel anxious. In contrast, the acute diseases that arise are acute poisoning, diarrhea, ARI, eye disease, vertigo, miscarriage, skin disease.

scholarly journals Processed and Unprocessed Red Meat Consumption and Risk for Type 2 Diabetes Mellitus: An Updated Meta-Analysis of Cohort Studies

2021 ◽  
Vol 18 (20) ◽  
pp. 10788
Author(s):  
Rui Zhang ◽  
Jialin Fu ◽  
Justin B. Moore ◽  
Lee Stoner ◽  
Rui Li
Keyword(s):  
Diabetes Mellitus ◽  
Cohort Studies ◽  
Fixed Effects ◽  
English Language ◽  
Meta Analysis ◽  
Meat Consumption ◽  
Type Ii Diabetes Mellitus ◽  
Red Meat ◽  
The Body ◽  
Cochrane Library

Type II diabetes mellitus (T2DM) is a metabolic disorder that occurs in the body because of decreased insulin activity and/or insulin secretion. The incidence of T2DM has rapidly increased over recent decades. The relation between consumption of different types of red meats and risk of T2DM remains uncertain. This meta-analysis was conducted to quantitatively assess the associations of processed red meat (PRM) and unprocessed red meat (URM) consumption with T2DM. We searched PubMed, Embase, Web of Science and The Cochrane Library for English-language cohort studies published before January 2021. Summary relative risks (RR) with 95% confidence interval (CI) were estimated using fixed effects and random effects. Additionally, dose–response relationships were explored using meta-regression. Fifteen studies (N = 682,963 participants, cases = 50,675) were identified. Compared with the lowest intake group, high consumption of PRM and URM increased T2DM risk by 27% (95% CI 1.15–1.40) and 15% (95% CI 1.08–1.23), respectively. These relationships were consistently strongest for U.S-based studies, though the effects of sex are inconclusive. In conclusion, PRM and URM are both positively associated with T2DM incidence, and these relationships are strongest in the U.S. reduction of red meat consumption should be explored as a target for T2DM prevention initiatives.

scholarly journals ОПТИМІЗАЦІЯ ПО КРИТЕРІЮ ПРОДУКТИВНОСТІ ДІАГНОСТИЧНО - ОЗДОРОВЧОГО КОМПЛЕКСУ «QUANTON»

2019 ◽  
pp. 137-146
Author(s):  
Ігор Миколайович Огородник ◽  
Олена Володимирівна Висоцька ◽  
Олег Васильович Крутов
Keyword(s):  
Human Body ◽  
Physiological State ◽  
Work Organization ◽  
Performance Criterion ◽  
Wave Action ◽  
The Body ◽  
Diagnostic Process ◽  
Physical Parameters ◽  
General Process ◽  
Resonance Effects

The object of the research is the computerized health-improving complex “Quanton” and the process of its optimization by the performance criterion. This complex is designed for quick non-invasive diagnostics of the man and restoration of their functional and physiological state using quantum-wave action. It allows the human body to independently determine the characteristics of this action. The principle of operation of this complex is based on the identified fundamental laws of the reactions of the human body to certain electro-wave bio-resonance effects. These patterns are manifested in the form of changes in the values of individual physical parameters of the body, which can be objectively measured and used to determine the desired characteristics of healing effects. One of the most problematic issues of the existing samples of the complex is an insufficient performance, mainly by the consistent principle of work organization and using the manual method of obtaining and processing a significant amount of information when performing the diagnostic process. At the same time, the functionality of this complex can be realized with the help of various at the level of technicalization of the element base and various parametric solutions.The method of complex structural-parametric optimization was used. Optimization is made according to the general process of diagnosis and the normalization of the body. At the same time, many typical ways to manage the performance of technical objects were used. Increased productivity of the computerized health and fitness complex “Quanton” was achieved due to:- minimization of the initial scope of work based on the results of an integrated assessment of the radiation spectrum of the body;- improving the speed of preparatory work by automating the process of finding and using multi-contact sensors;- minimizing the time of the test signals;- the use of information markers, the content of which is based on the principle of hierarchical information subordination;- minimization of the duration of the main wave action due to the body's independent choice of this duration;- minimizing the number of sessions.According to the results of applying these techniques, the possibility of increasing the performance of the “Quanton” complex up to 8.7 times was established.

GEOECOLOGICAL ASSESSMENT OF THE MODERN ZINC CONTENT IN THE SOIL COVER OF THE URBANIZED TERRITORIES OF THE SOUTH OF RUSSIA

2021 ◽  
Vol 82 (3) ◽  
pp. 115-120
Author(s):  
SINTSOV ALEXANDER V. ◽  
◽  
BARMIN ALEXANDER N. ◽  
ZIMOVETS PETR A. ◽  
VALOV MICHAIL V. ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Maximum Permissible Concentration ◽  
Soil Cover ◽  
Chemical Elements ◽  
Zinc Content ◽  
Soil Samples ◽  
The Body ◽  
Urbanized Area ◽  
The Impact ◽  
The City

Anthropogenic and technogenic processes in the urban environment significantly change the chemical composition of the soil cover. One of such processes influencing the state of the urban soil is the process of soil cover pollution with heavy metals. Heavy metals are biochemically active and highly toxic; they are found in various components of the natural environment, as well as in systems of anthropogenic and technogenic origin. They have the property of accumulation in the body of living beings and have a negative effect on their condition. This group of chemical elements includes lead, zinc, chromium, mercury, copper, iron and other metals. Exceeding the permissible concentration of heavy metals in the soil of an urbanized area and their toxic effects pose a significant danger to humans. Contamination of the soil cover of an urbanized area with heavy metals is associated with the impact of a large number of sources of anthropogenic and technogenic origin, namely, energy and industrial facilities, city infrastructure support systems, zones of construction activities and storage of materials or waste. One of the main highly toxic chemical pollutants of the soil cover of the urbanized territory belonging to the group of heavy metals is zinc «Zincum-Zn». The article describes the results of a 2020 study of the current zinc content in the soil cover of the city of Astrakhan. The relevance of the work lies in the geochemical analysis of the content of heavy metals in the soil of the city of Astrakhan. The aim of the work was to study the modern process of soil contamination of the city of Astrakhan with zinc. The work was based on the task of determining the degree of exceeding the hygienic standards of the maximum permissible concentration of zinc in soil samples. Methods of geographical and ecological research were used in the work, soil samples were collected, followed by determination of the concentration of a substance in each of the soil samples in a certified laboratory. In the course of the work, the indicators of exceeding the maximum permissible concentration of zinc in the soil of the city of Astrakhan were determined and the presumptive sources of pollution were identified.

Profil Terapi Antidiabetes Oral Pada Pasien Diabetes Mellitus Tipe II Di Instalasi Rawat Jalan Rumah Sakit Anwar Medika

2021 ◽  
Vol 3 (2) ◽  
pp. 137-150
Author(s):  
Adinugraha Amarullah ◽  
◽  
Dwi Febriyani ◽  
Farida Anwari ◽  
Khurin In Wahyuni ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Prescription Drugs ◽  
Type Ii Diabetes ◽  
Data Retrieval ◽  
Nutritional Therapy ◽  
Type Ii Diabetes Mellitus ◽  
The Body ◽  
Type Ii ◽  
Antidiabetic Therapy ◽  
Data Collection Sheet

Diabetes Mellitus (DM) is a chronic condition because of the body cannot produce insulin normally or insulin cannot work effectively. This damage if chronic occurs will cause complications. In the province of East Java the prevalence of DM sufferers of 2.1% ranks 9th, and prevalence of DM in Sidoarjo is patients with a diagnosis of 3.6% of the total population of East Java. The purpose of this study was to look at the profile of oral antidiabetic therapy in type II diabetes mellitus patients in the outpatient installation of Anwar Medika Hospital. The sampling method used is non random sampling Data retrieval from 17 February to 30 April 2020 with a data collection sheet that has been validated. Management of DM patients consists of 4pillars that is education, nutritional therapy, physical activity and pharmacology. The study was conducted in an outpatient installation of Anwar Medika Hospital with 62 samples that fit the inclusion criteria. The results showed that most patients with type II diabetes mellitus were female, as many as 44 patients (70.96%) of 62 patients. Patients with type II diabetes mellitus who most went to Anwar Medika Hospital and got ADO prescription drugs were patients with an age range of 56-65 years as many as 24 patients (38.70%) of 62 patients. Most of the most commonly prescribed ADO drugs by doctors were Glimepirid 34 (91,89%) and combination of 2 kinds of drugs by 22 patients (88%) out of 62 patients. Most patients use more than 1 drug. It is therefore recommended that pharmacy installation officers at Anwar Medika Hospital can provide an understanding of DM, provide counseling related to medicines prescribed to patients and monitor the success of patient therapy. This research is worthy of ethics with numberNo.633/RSAM/VII/2020

scholarly journals Effects of Heavy Metal Toxicity on Anxiety Disorder

2021 ◽  
Vol 2 (8) ◽  
pp. 660-668
Author(s):  
Mfem CC ◽  
Seriki SA ◽  
Oyama SE
Keyword(s):  
Heavy Metals ◽  
Heavy Metal ◽  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Human Body ◽  
The Body ◽  
Panic Attacks ◽  
Control Group ◽  
Group 2 ◽  
High Doses

Background: Several heavy metals are found naturally in the earth crust and are exploited for various industrial and economic purposes. Among these heavy metals, a few have impact on the human body. Though some of these metals only have effect on human physiology in high doses, others such as cadmium, mercury, lead, chromium, silver, and arsenic have delirious effects in the body even in minute quantities, causing acute and chronic toxicities in human. Anxiety is a common psychiatric disorder among men and women. Occasional anxiety may be a normal a part of life. However, people with anxiety disorders frequently have intense, excessive and persistent worry and fear about everyday situations. Often, anxiety disorders involve repeated episodes of sudden feelings of intense anxiety and fear or terror that reach a peak within minutes (panic attacks). This study examined a major environmental risk factor of anxiety disorder and how the adverse impact of anxiety disorder could be ameliorated using zinc and vitamin E. Methods: Animals used for the researched were grouped into four. Group 1 represents control group; Group 2 represents animals exposed a heavy metal (CaCl2); Group 3 represents animals exposed to CaCl2 and then treated with zinc; and Group 4 represents animals exposed to CaCl2 and then treated vit E. Results: Results showed that exposure to heavy metals (CaCl2 in particular) causes severe anxiety disorders. Results also showed zinc and vit E have the capacity to ameliorate anxiety disorder caused by heavy metals. Conclusion: The human body should be adequately protected as man interacts with heavy metals to prevent anxiety disorder, and where a patient becomes a victim of the disorder, zinc and vit E could be used to manage the case.

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