scholarly journals Chemical profiles and antimicrobial activities of plants utilized in Brazilian traditional medicine

2021 ◽  
Vol 46 (1) ◽  
pp. 35-40
Author(s):  
Rafaela Souza Silva ◽  
Marcílio Wagner Fontes Da Silva ◽  
Giselle Barbosa Bezerra ◽  
Clécio Souza Ramos
Keyword(s):  
Medicinal Plants ◽  
Scientific Evidence ◽  
Antimicrobial Activities ◽  
Chemical Compositions ◽  
Gram Negative Bacteria ◽  
Traditional Medicinal Plants ◽  
Primary Health ◽  
Chemical Profiles ◽  
Alternative Sources ◽  
Strong Antimicrobial Activity

Medicinal plants are used for primary health care in many countries. In Brazil, there are hundreds of street markets selling a wide variety of herbs for medicinal purposes without quality control or scientific evidence; instead, their purported efficacy is based exclusively on empirical ethnobotanical knowledge. The present study evaluated the effectiveness of five medicinal plants widely utilized in Brazil to treat infections, as well as determined their chemical profiles. The results revealed that the five plants investigated (Anacardium occidentale L., Handroanthus impetiginosus Mart., Bumelia sartorum Sw., Zornia brasiliensis Vogel and Cnidosculus urens Pohl) demonstrated moderate to strong antimicrobial activity against most fungi and bacteria tested, principally for infections caused by gram-negative bacteria. The extracts of four plants exhibited MIC of 19.5 µg mL-1 against the bacterium Escherichia coli. The results also confirmed that these five traditional medicinal plants are efficient and inexpensive alternative sources of substances to treat infections. The samples of the commercially marketed plants did not have consistent chemical compositions in at least one type of HPLC, GC/MS, UV or 1H NMR analysis.

scholarly journals A study of antimicrobial activities of aqueous and ethanolic extract of bee pollen against

2021 ◽  
Author(s):  
Kasim Roba Jilo
Keyword(s):  
Medicinal Plants ◽  
Aqueous Extract ◽  
Antimicrobial Properties ◽  
Ethanolic Extract ◽  
Antimicrobial Activities ◽  
Distilled Water ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Bee Pollen ◽  
Stock Solutions

Abstract Background Ethiopia is one of the plant species-rich countries in the world and the center of origin of many medicinal plants. Studying antimicrobial activities of pollen is vivacious to investigate plant resources for medicinal values and the study was conducted to evaluate antimicrobial properties of bee pollen against mentioned bacteria. Methods Completely Randomized Design was used for laboratory work. After adjusting turbidity, consistent growth of bacterial culture was made using a sterilized cotton swab. 20 grams of bee pollen was added to 200 ml of distilled water as well as ethanol and finally, the extract was filtered by Whatman filter by paper, dried and weighted and stock solutions were made as follows,3.6 gm. was added to 12 ml of distilled water to prepare stock solutions as follows 3.6:12 = 0.3 x \({10}^{6}\) = 3 x \({10}^{5}\) ppm stock solution and antimicrobial activities of pollen were tested against mentioned bacteria. Data were imported to R software version 3.44. Multilevel analysis was used to see the interaction between bacteria species and each concentration of pollen and Anova was used to see the significance of these concentrations on bacteria species. A p-value of < 0.05 was considered statistically significant. Results Results indicated that bacteria were more inhibited at 72 hours than 48 and 24 hours and the results showed an ethanolic extract of bee pollen had antimicrobial activities against both Gram-negative and Gram-positive bacteria mentioned above. Time has significant effects on tested bacteria (p = 0.000) and treatments have significant effects on tested organisms (p = 0.000). The ethanolic extract inhibited the growth of more Gram-negative bacteria: Escherichia coli and Shigella boydii. Bacillus subtilis was mostly inhibited by aqueous extract of bee pollen than others. Conclusions Ethanolic extract of pollen had antibacterial activities against all tested bacterial strains even though it is concentration and time-based. The ethanolic extract inhibited more Gram-negative bacteria relatively while aqueous extract inhibited more Gram-positive relatively. Negative controls (sterilized water) didn’t show any antimicrobial properties, while positive control (Chloramphenicol) had antimicrobial activities. Further isolation and characterization of bioactive compounds from pollen are useful to develop a novel botanical formulation for further applications from the pollen of medicinal plants.

scholarly journals Antibacterial activity in the leaves of seven bitter medicinal plants of Bangladesh

1970 ◽  
Vol 18 ◽  
pp. 128-133 ◽  
Author(s):  
MTH Molla ◽  
MS Ahsan ◽  
MT Alam ◽  
ME Haque
Keyword(s):  
Antibacterial Activity ◽  
Bacillus Subtilis ◽  
Medicinal Plants ◽  
Plant Extracts ◽  
Salmonella Typhi ◽  
Antimicrobial Activities ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Ethanolic Extracts

Context: Development of resistance in human pathogens against conventional antibiotic necessitates searching indigenous medicinal plants having antibacterial property. Seven medicinal plants used actively in folklore, ayurvedic and traditional system of medicine were selected for the evaluation of their antimicrobial activity for this study.   Objectives: Evaluation of the effectiveness of some medicinal plant extracts against four Gram-positive and five Gram-negative bacteria.  Materials and Methods: The antibacterial activity of the crude ethanolic extracts obtained from the leaves of seven medicinal plants; viz., Andrographis paniculata, Catharanthus roseus, Adhatoda vasica, Vitex vegundo, Aloe vera, Flacortia ramontchi and Nyctanthes arbortristis were tested against nine bacteria at concentrations of 300-, 400- and 500 μg/ml. Standard antibiotic disc kanamycin (30μg/ml) was used for comparison. The minimum inhibitory concentration (MIC) of ethanolic extracts of the leaves of these medicinal plants were determined by testing the extracts on four Gram-positive and five Gram-negative bacteria by serial tube dilution method.   Results: All the extracts have notable antimicrobial activities against the test organisms. The ethanolic extracts of the leaves showed the highest antimicrobial activities against Bacillus megaterium and Shigella dysenteriae for An. paniculata, Ad. vasica and Al. vera; Bacillus subtilis and Salmonella typhi for C. roseus and N. arbortristis; Staphylociccus aureus and Salmonella typhi for V. vegundo; and Bacillus subtilis and Shigella sonnei for F. ramontchi respectively. The extract of the plants had MIC values ranging from 32 to 128 mg/ml. All plant extracts showed no MIC against Shigella shiga and against Sarcina lutea only C. roseus showed MIC 128 mg/ml.   Conclusion: The results revealed that the ethanolic extracts of the plants under present investigation have notable antimicrobial activities.   Keywords: medicinal plants; antimicrobial screening; MIC; bacteria. DOI: http://dx.doi.org/10.3329/jbs.v18i0.8788 JBS 2010; 18(0): 128-133

Antimicrobial Flavonoids from Artocarpus anisophyllus Miq. and Artocarpus lowii King

2014 ◽  
Vol 71 (1) ◽  
Author(s):  
Shajarahtunnur Jamil ◽  
Siti Mariam Abdul Lathiff ◽  
Siti Awanis Abdullah ◽  
Noraini Jemaon ◽  
Hasnah Mohd Sirat
Keyword(s):  
Antimicrobial Agents ◽  
Inhibition Zone ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Qualitative Assay ◽  
Concentration Methods ◽  
Strong Antimicrobial Activity

Antimicrobial activities of flavonoids isolated from the leaves and heartwoods of Artocarpus anisophyllus Miq. and Artocarpus lowii King were evaluated. Gram positive bacteria (Staphylococcus aureus and Bacillus cereus), Gram negative bacteria (Escherichia coli and Pseudomonas putida) and fungi (Candida albicans and Candida glabrata) were used in this study. Disc diffusion method was used as the qualitative assay while minimum inhibitory concentration and minimum microbicidal concentration methods were used as the quantitative assays. Artocarpin (8) showed strong antimicrobial activity towards all bacteria with inhibition zone diameter more than 11 mm and minimum microbicidal concentration value of 0.45 mg/mL. Isobavachalcone (3) exhibited strong antibacterial activity towards Gram positive bacteria with minimum microbicidal concentration value of 0.45 mg/mL. The findings of this study revealed that the isolated flavonoids from A. anisophyllus and A. lowii have potential to be developed as antimicrobial agents.

scholarly journals A COMPARATIVE PHARMACOGNOSTIC STUDY OF THE TWO Orthoshipon aristatus (BLUME) MIQ. VARIETIES

2021 ◽  
Vol 9 (Spl-2-ICOPMES_2020) ◽  
pp. S228-S233
Author(s):  
Fahrauk Faramayuda ◽  
◽  
Silvy Julian ◽  
Ari Sri Windyaswari ◽  
Totik Sri Mariani ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Scientific Evidence ◽  
Colorimetric Method ◽  
Ethanolic Extract ◽  
European Countries ◽  
Active Ingredients ◽  
White Variety ◽  
Traditional Medicinal Plants ◽  
Cat’S Whiskers

The use of a plant as an ingredient in traditional medicine requires scientific evidence to determine its properties. Cat's whiskers (Orthosiphon aristatus) is one of the widely used traditional medicinal plants in various Asian and European countries. This study aimed to determine the pharmacognostic properties of purple and white varieties of O. aristatus. Aqueous and ethanolic extract of the stem and leaves of purple and white varieties of O. aristatus was prepared and investigated for the presence of active ingredients. The AlCl3 colorimetric method was used for the estimation of flavones and flavonols. The level of flavonoid was reported 13.06 ± 0.13 mg QE / 1g and 6.17 ± 0.049 mg QE / 1g for the leaves and stem extracts of purple varieties respectively while this value was reported 9.76 ± 0.15 mg QE / 1g and 3.79 ± 0.03 mg QE / 1g for the white variety. From the results of the study, it can be concluded that the purple variety has a significantly higher amount of flavonoid then the white variety.

scholarly journals Can Scientific Evidence Support Using Bangladeshi Traditional Medicinal Plants in the Treatment of Diarrhoea? A Review on Seven Plants

Nutrients ◽  
2013 ◽  
Vol 5 (5) ◽  
pp. 1757-1800 ◽  
Author(s):  
Helle Wangensteen ◽  
Line Klarpås ◽  
Mahiuddin Alamgir ◽  
Anne Samuelsen ◽  
Karl Malterud
Keyword(s):  
Medicinal Plants ◽  
Scientific Evidence ◽  
Traditional Medicinal Plants

scholarly journals Efficacy and Mechanism of Traditional Medicinal Plants and Bioactive Compounds against Clinically Important Pathogens

Antibiotics ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 257 ◽  
Author(s):  
Mickymaray
Keyword(s):  
Antimicrobial Activity ◽  
Medicinal Plants ◽  
Bioactive Compounds ◽  
Antimicrobial Agents ◽  
Antimicrobial Activities ◽  
Pharmacological Agents ◽  
Antibiotic Resistant ◽  
Diverse Range ◽  
Traditional Medicinal Plants ◽  
Wide Range

Traditional medicinal plants have been cultivated to treat various human illnesses and avert numerous infectious diseases. They display an extensive range of beneficial pharmacological and health effects for humans. These plants generally synthesize a diverse range of bioactive compounds which have been established to be potent antimicrobial agents against a wide range of pathogenic organisms. Various research studies have demonstrated the antimicrobial activity of traditional plants scientifically or experimentally measured with reports on pathogenic microorganisms resistant to antimicrobials. The antimicrobial activity of medicinal plants or their bioactive compounds arising from several functional activities may be capable of inhibiting virulence factors as well as targeting microbial cells. Some bioactive compounds derived from traditional plants manifest the ability to reverse antibiotic resistance and improve synergetic action with current antibiotic agents. Therefore, the advancement of bioactive-based pharmacological agents can be an auspicious method for treating antibiotic-resistant infections. This review considers the functional and molecular roles of medicinal plants and their bioactive compounds, focusing typically on their antimicrobial activities against clinically important pathogens.

Ethnobiological survey of Maasai traditional medicinal plants

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
E Makule ◽  
J Heilmann ◽  
B Kraus
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicinal Plants

Extraction and Phytochemicals Determination of Traditional Medicinal Plants for Anti-microbial Susceptibility Test

2020 ◽  
Vol 2020 ◽  
Author(s):  
Firew Admasu
Keyword(s):  
Antimicrobial Activity ◽  
Medicinal Plants ◽  
Traditional Medicine ◽  
Crude Extract ◽  
Susceptibility Test ◽  
Plant Sample ◽  
Traditional Medicinal Plants ◽  
Traditional Health Care ◽  
Susceptibility Tests

Abstract: The study were conducted at Dilla University, College of Natural Sciences, Biological Sciences laboratories. Background: Ethiopia is a country with many ethnic groups, cultures and beliefs which in turn have contributed to the high diversity of traditional health care knowledge and practices of traditional medicine from local growth plants, animals and minerals for various physical and mental disorders of human and livestock population that passed from generation to generation for centuries. Medicinal plants contributors to pharmaceutical, agricultural and food industries in the world. The use of medicinal plants in the industrialized societies has been traced to extraction and development of several drugs used in order to heel some diseases having inhibiting effect against pathogenic microorganism. Objective: The main objective of this study was Extraction and Phytochemicals determination of traditional medicinal plants for anti microbial susceptibility test. Methodology: The extraction and identification of some phytochemicals crude compound which used for antimicrobial susceptibility test from plant sample such as Ocimum lamiifolium (OL), Croton maerosth (Cm) and Ruta chalepesis (RC) were conducted. Plant samples are collected, powdered using mortal and pistil and extracted using ethanol and some susceptibility tests were performed to identify some phytochemicals compound. Result: The main result of Antimicrobial activity test showed that the crude extract of OL has the highest zone of inhibition. The highest yield of crude extract (38.21%) was obtained from Croton maerosth (CM) which followed by Ruta chalepesis (RC) (32.43%). However, the lowest yield (28.37%) was obtained from Oscpmum lamifolium (OL). Conclusion: Traditional Medicine is used by many people to managing numerous conditions; it’s accessible and effective on antimicrobial activity. Therefore, it plays a significant role by reducing life-threatening ailments of people and other animals.

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