Low Birth Weight and Neonatal Mortality: Meta Analysis

Author(s):  
Silvalia Rahma Pratiwi ◽  
◽  
Hanung Prasetya ◽  
Bhisma Murti ◽  
◽  
...  

ABSTRACT Background: Low birth weight (LBW) has been used as an important public health indicator. LBW is one of the key drivers and indirect causes of neonatal death. It contributes to 60% to 80% of all neonatal deaths, annually. This study aimed to examine association between LBW and neonatal mortality using meta analysis. Subjects and Methods: This was meta-analysis and systematic review. Published articles in 2010-2020 were collected from Google Scholar, PubMed, Springer Link, Hindawi, Clinical Key, ProQuest databases. Keywords used “low birth weight” AND “mortality” OR “birth weight mortality” OR “neonatal death” AND “cross sectional” AND “adjusted odd ratio”. The inclusion criteria were full text, using cross-sectional study design, and reporting adjusted ratio. The data were analyzed by PRISMA flow chart and Revman 5.3. Results: 6 studies were met criteria. This study showed that low birth weight increased the risk of neonatal mortality (aOR= 2.23; 95% CI= 1.12 to 4.44; p= 0.02). Conclusion: Low birth weight increases the risk of neonatal mortality. Keywords: low birth weight, mortality, neonatal death Correspondence: Silvalia Rahma Pratiwi. Masters Program in Public Health. Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 082324820288. DOI: https://doi.org/10.26911/the7thicph.03.113

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Duah Dwomoh

Abstract Background Ghana did not meet the Millennium Development Goal 4 of reducing child mortality by two-thirds and may not meet SDG (2030). There is a need to direct scarce resources to mitigate the impact of the most important risk factors influencing high neonatal deaths. This study applied both spatial and non-spatial regression models to explore the differential impact of environmental, maternal, and child associated risk factors on neonatal deaths in Ghana. Methods The study relied on data from the Ghana Demographic and Health Surveys (GDHS) and the Ghana Maternal Health Survey (GMHS) conducted between 1998 and 2017 among 49,908 women of reproductive age and 31,367 children under five (GDHS-1998 = 3298, GDHS-2003 = 3844, GDHS-2008 = 2992, GDHS-2014 = 5884, GMHS-2017 = 15,349). Spatial Autoregressive Models that account for spatial autocorrelation in the data at the cluster-level and non-spatial statistical models with appropriate sampling weight adjustment were used to study factors associated with neonatal deaths, and a p-value less than 0.05 was considered statistically significant. Results Population density, multiple births, smaller household sizes, high parity, and low birth weight significantly increased the risk of neonatal deaths over the years. Among mothers who had multiple births, the risk of having neonatal deaths was approximately four times as high as the risk of neonatal deaths among mothers who had only single birth [aRR = 3.42, 95% CI: 1.63–7.17, p < 0.05]. Neonates who were perceived by their mothers to be small were at a higher risk of neonatal death compared to very large neonates [aRR = 2.08, 95% CI: 1.19–3.63, p < 0.05]. A unit increase in the number of children born to a woman of reproductive age was associated with a 49% increased risk in neonatal deaths [aRR = 1.49, 95% CI: 1.30–1.69, p < 0.05]. Conclusion Neonatal mortality in Ghana remains relatively high, and the factors that predisposed children to neonatal death were birth size that were perceived to be small, low birth weight, higher parity, and multiple births. Improving pregnant women’s nutritional patterns and providing special support to women who have multiple deliveries will reduce neonatal mortality in Ghana.


2016 ◽  
Vol 25 (4) ◽  
Author(s):  
Maria Aparecida Munhoz Gaiva ◽  
Elizabeth Fujimori ◽  
Ana Paula Sayuri Sato

ABSTRACT This was a cross-sectional study that investigated maternal and child factors associated with neonatal mortality. Data was obtained from the Live Births and Mortality Information Systems integrated by linkage. A total of 9,349 live births and 78 deaths in the neonatal period, which occurred in 2010 in Cuiabá-MT were analyzed. Univariate and multivariate analyzes were performed. In the multiple logistic regression, neonatal mortality was associated with: maternal age less than 20 years; prematurity; low birth weight; Apgar score less than seven at 1 and 5 minutes; and presence of congenital anomaly. The results highlight the need to improve the quality of prenatal care in order to prevent low birth weight and prematurity. The association between neonatal death and low Apgar score at 1 and 5 minutes indicates the importance of investments in delivery care.


Author(s):  
Imam Setya Arifian ◽  
◽  
Vitri Widyaningsih ◽  
Hanung Prasetya ◽  
◽  
...  

ABSTRACT Background: Intrauterine exposure to tobacco smoke has been discerned as an important risk factor for low birth weight, small for gestational age, and preterm birth infants. The purpose of this study was to investigate the effect of active smokers in pregnant women on low birth weight. Subjects and Method: This was meta analysis and systematic review. The study was conducted by collecting published articles from Google Scholar, and PubMed databases, from year 2010 to 2020. Keywords used “Maternal Smoking” OR “Low Birth Weight” AND “cross sectional”. The study subject was pregnant women. Intervention was active tobacco smokers with comparison non-smokers. The study outcome was low birthweight. The collected articles were selected by PRISMA flow chart. The quantitative data were analyzed using Revman 5.3. Results: 4 studies from Brazil, East Ethiopia, Southern Ethiopia, Turkey, Taiwan, and Romania reported that active smokers in pregnant women increased the risk of low birthweight (aOR= 2.17; 95% CI= 1.05 to 4.51; p<0.001). Conclusion: Active smokers in pregnant women increase the risk of low birthweight. Keywords: active smokers, pregnant women, low birth weight Correspondence: Imam Setya Arifian. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 0852 5340 2793. DOI: https://doi.org/10.26911/the7thicph.03.132


2014 ◽  
Vol 48 (5) ◽  
pp. 778-786 ◽  
Author(s):  
Maria Aparecida Munhoz Gaiva ◽  
Elizabeth Fujimori ◽  
Ana Paula Sayuri Sato

Objective To evaluate the factors associated with neonatal mortality in infant born with low birth weight. Method Cross-sectional study that analyzed data from 771 live births with low birth weight (<2500 g) in the city of Cuiabá, MT, in 2010, of whom 54 died in the neonatal period. We obtained data from the Information System on Live Births and Mortality, by integrated linkage. Results In multiple logistic regression, neonatal mortality was associated with: number of prenatal visits less than 7 (OR=3.80;CI:1,66-8,70); gestational age less than 37 weeks (OR=4.77;CI:1.48-15.38), Apgar score less than 7 at the 1st minute (OR=4.25;CI:1.84-9.81) and the 5th minute (OR=5.72,CI:2.24-14.60) and presence of congenital anomaly (OR=14.39;IC:2.72-76.09). Conclusion Neonatal mortality in infants with low birth weight is associated with avoidable factors through adequate attention to prenatal care, childbirth and infants.



Author(s):  
Irfa Nur Faujiah ◽  
◽  
Bhisma Murti ◽  
Hanung Prasetya ◽  
◽  
...  

ABSTRACT Background: Low birth weight remains a major public health concern of neonatal mortality rate, especially in developing countries. The mother’s psychological stress during pregnancy was reported as one of the causes of low birth weight in children. This study aimed to determine the effect of prenatal stress on low birth weight. Subjects and Method: This was a meta-analysis and systematic review. This study was conducted by collecting articles from PubMed, Google Scholar, Science Direct, Directory of Open Access (DOAJ), Springer Link databases, from 2006-2020. Keywords used “Prenatal Stress” AND “Low Birth Weight”. The inclusion criteria were open access and full text articles, using English or Indonesia language, pregnant women with stress, using cohort study design, and reporting adjusted odds ratio (aOR). The articles were selected by PRISMA flow chart. The quantitative data were analyzed using random effect model run on Revman 5.3. Results: 5 studies from United States, Suriname, Macao, Israel, and South Africa reported that prenatal stress increased the risk of low birth weight (aOR= 1.94; 95% CI= 1.33 to 2.81; p<0.001), with I2= 0%; p= 0.45. Conclusion: Prenatal stress increases the risk of low birth weight. Keywords: prenatal stress, low birth weight Correspondence: Irfa Nur Faujiah. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: +6282127200347. DOI: https://doi.org/10.26911/the7thicph.03.123


2021 ◽  
Vol 8 ◽  
pp. 2333794X2110196
Author(s):  
Sitotaw Molla Mekonnen ◽  
Daniel Mengistu Bekele ◽  
Fikrtemariam Abebe Fenta ◽  
Addisu Dabi Wake

Necrotizing enterocolitis (NEC) remains to be the most critical and frequent gastrointestinal disorder understood in neonatal intensive care units (NICU). The presented study was intended to assess the prevalence of NEC and associated factors among enteral Fed preterm and low birth weight neonates. Institution based retrospective cross-sectional study was conducted on 350 enteral Fed preterm and low birth weight neonates who were admitted at selected public hospitals of Addis Ababa from March 25/2020 to May 10/2020. The data were collected through neonates’ medical record chart review. A total of 350 participants were enrolled in to the study with the response rate of 99.43%. One hundred eighty-four (52.6%) of them were male. The majority 123 (35.1%) of them were (32 + 1 to 34) weeks gestational age. The prevalence of NEC was (25.4%) (n = 89, [95% CI; 21.1, 30.0]). Being ≤28 weeks gestational age (AOR = 3.94, 95% CI [2.67, 9.97]), being (28 + 1 to 32 weeks) gestational age (AOR = 3.65, 95% CI [2.21, 8.31]), birth weight of 1000 to 1499 g (AOR = 2.29, 95% CI [1.22, 4.33]), APGAR score ≤3 (AOR = 2.34, 95% CI [1.32, 4.16]), prolonged labor (AOR = 2.21, 95% CI [1.35, 6.38]), maternal chronic disease particularly hypertension (AOR = 3.2, 95% CI [1.70, 5.90]), chorioamnionitis (AOR = 4.8, 95% CI [3.9, 13]), failure to breath/resuscitated (AOR = 2.1, 95% CI [1.7, 4.4]), CPAP ventilation (AOR = 3.7, 95% CI [1.50, 12.70]), mixed milk (AOR = 3.58, 95% CI [2.16, 9.32]) were factors significantly associated with NEC. Finally, the prevalence of NEC in the study area was high. So that, initiating the programs that could minimize this problem is required to avoid the substantial morbidity and mortality associated with NEC.


BMJ Open ◽  
2012 ◽  
Vol 2 (1) ◽  
pp. e000327 ◽  
Author(s):  
Ryosuke Sato ◽  
Hiroshi Watanabe ◽  
Kenji Shirai ◽  
Shigeru Ohki ◽  
Rieko Genma ◽  
...  

2017 ◽  
Vol 15 (2) ◽  
pp. 169-173 ◽  
Author(s):  
Kamal Prasad Kandel ◽  
Sindhu Kafle

Background: Babies with a birth weight of less than 2500 grams, irrespective of the period of their gestation are termed as Low Birth Weight (LBW) babies. Despite consistent efforts to improve the quality of maternal and child health, more than twenty million low birth-weight (LBW) babies are born every year throughout the world. Though, the health situation of Nepal has improved substantially over the years, the low birth-weight (LBW) rate is still high. The objective of this study was to assess the proportion of low birth weight and identify the associated factors for low birth weight in a live born infant among the institutionally delivered newborns. Methods: A hospital based cross sectional study was conducted in Obstetrics and Gynaecology ward of Bharatpur hospital, Bharatpur, from 17th September to 4th October , 2012. Altogether 480 respondents were taken and respondents were mothers who had delivered newborns in Bharatpur hospital.Results: A total of 480 births occurred during the study period, of which 480 met the study criteria. Among which 9.4% were low birth weight and 90.6% were normal birth weight .Overall mean birth weight was found to be 2.96 kg. Out of total 9.4% newborns were weighing less than 2.50 kg and mean birth weight 2.96kg. Conclusions: This study suggests that there were several factors interplaying which lead to LBW babies; which are age of mother at delivery,weight gain by mother during pregnancy, short, low body mass index and hyperemesis gravidarum was the strongest predictor in this study.


2021 ◽  
Vol 6 (2) ◽  
pp. 111
Author(s):  
Hepti Muliyati ◽  
Menis Mbali ◽  
Hadidja Bando ◽  
Riana Pangestu Utami ◽  
Opyn Mananta

Wasting on children is an important public health problem because of its considerable impact on their health and growth. This problem could lead to iron deficiency which could induce infection disease and probably lower a child’s intelligence as a long-term effect. This study aimed to analyze factors related to wasting on 12-59 months children in Bulili Public Health Center (PHC), Palu City. The analytical descriptive study designed with a cross-sectional approach was applied in this study. One hundred and twenty-one subject was selected from 283 children with purposive sampling technique. Data were analyzed with chi-square and Fisher exact test with significant (p < 0,05). The result showed that most children with low birth weight experienced wasting with a p-value = 0,000. Most of the children from higher-income families did not experience wasting with a p-value = 0,004. Most children who didn’t receive breastfeeding milk did not experience wasting with a p-value = 0,958. This study concluded a correlation between low birth weight and income to wasting, but breastfeeding practice was not related.


2017 ◽  
Vol 11 (2) ◽  
pp. 20-23
Author(s):  
Safiur Rahman Ansari ◽  
Gehanath Baral

Aims: To examine the association between maternal hemoglobin with birth weight.Methods: Cross sectional study of obstetrics database at Paropakar Maternity and Women’s Hospital. Hospital delivery of over 18 years of age women tested for Pearson correlation using SPSS-17.Results: Total of 2085 cases analyzed. There was mean hemoglobin value of 12.05 ± 1.30 (95% CI=11.992-12.103) g/dL and no any significant impact on mode of delivery (p=0.15) and neonatal death (p=0.736). There was a small but a significant correlation (p<0.01) of maternal age with hemoglobin (r = 0.106) and birth weight (r = 0.093); but a very small negative correlation between maternal hemoglobin and birth weight.Conclusions: Optimal maternal hemoglobin during labor rules out any strong correlation with birth weight.


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