scholarly journals Effects of Dexamethasone, Metoclopramide or Acepromazine on Emesis in Cats Sedated with Xylazine Hydrochloride

2006 ◽  
Vol 75 (2) ◽  
pp. 299-303 ◽  
Author(s):  
A. Topal ◽  
N. Y. Gül

This study was designed to determine antiemetic efficacy of prophylactic administration of dexamethasone, metoclopramide or acepromazine and their influence on sedation in cats sedated with xylazine hydrochloride. Ten healthy adult cats (5 males and 5 females) were used. The prophylactic antiemetic effects of dexamethasone (4 mg/kg of body weight, IM), metoclopramide (0.4 mg/kg of body weight, IM), acepromazine (0.1 mg/kg of body weight, IM) or saline (0.9% NaCI) solution (0.1 ml/kg, IM) administered 1 hour before administration of xylazine hydrochloride (2 mg/kg, IM) was evaluated. Initially, the cats were given saline treatment (day 0); sequentially they were given dexamethasone, metoclopramide or acepromazine at 1 week intervals. After a xylazine injection, all cats were observed for 90 minutes for the assesment of frequency of emesis, and the time until the onset of the first emetic episode, and the determination of xylazine-induced sedation time. Prior treatment with 4 mg/kg of dexamethasone significantly reduced the frequency of emetic episodes but no alteration was observed in the time until the onset of the first emetic episode after the xylazine injection. Metoclopramide and acepromazine did not alter the frequency of emetic episodes but metoclopramide significantly prolonged the onset of the first emetic episode. Dexamethasone (4 mg/kg, IM) significantly decreased the frequency of emetic episodes without affecting the time until the onset of the first emetic episode, xylazine-induced sedation in cats.

2015 ◽  
Vol 4 ◽  
Author(s):  
Margaret A. Gooding ◽  
Jim L. Atkinson ◽  
Ian J. H. Duncan ◽  
Lee Niel ◽  
Anna K. Shoveller

AbstractThe effects of dietary carbohydrate and fat on feline health are not well understood. The effects of feeding diets moderately high in fat (HF; n 10; 30 % fat, 26 % carbohydrate as fed) or carbohydrate (HC; n 10; 11 % fat, 47 % carbohydrate), for 84 d, were investigated in healthy, adult cats (3·5 (sd 0·5) years). Data on indirect calorimetry, blood biomarkers, activity, play and cognition were collected at baseline, and at intervals throughout the study. Body composition was measured by dual-energy X-ray absorptiometry at baseline and on day 85. There were no significant main effects of diet on body weight and composition. When data were analysed over study day within diet, cats fed HF diets experienced a significant increase in body fat (P = 0·001) and body weight (P = 0·043) in contrast to cats consuming the HC diet that experienced no change in body fat or body weight (P = 0·762) throughout the study. Overall, energy expenditure was similar between diets (P = 0·356 (fasted), P = 0·086 (postprandial)) and respiratory quotient declined with exposure to the HF diet and increased with exposure to the HC diet (P < 0·001; fasted and postprandial). There was no difference in insulin sensitivity as an overall effect of diet (P = 0·266). Activity declined from baseline with exposure to both diets (HC: P = 0·002; HF: P = 0·01) but was not different between diets (P = 0·247). There was no effect of diet on play (P = 0·387) and cats consuming either the HF or HC diet did not successfully learn the cognitive test. Overall, cats adapt to dietary macronutrient content, and the implications of feeding HC and HF diets on risk for adiposity as driven by metabolic and behavioural mechanisms are discussed.


2009 ◽  
Vol 235 (5) ◽  
pp. 579-579
Author(s):  
Mark J. Acierno ◽  
Mark A. Mitchell ◽  
Diana M. Freeman ◽  
Patricia J. Schuster ◽  
David Sanchez-Migallon Guzman ◽  
...  

2021 ◽  
pp. 1098612X2110137
Author(s):  
James R Templeman ◽  
Kylie Hogan ◽  
Alexandra Blanchard ◽  
Christopher PF Marinangeli ◽  
Alexandra Camara ◽  
...  

Objectives The objective of this study was to verify the safety of policosanol supplementation for domestic cats. The effects of raw and encapsulated policosanol were compared with positive (L-carnitine) and negative (no supplementation) controls on outcomes of complete blood count, serum biochemistry, energy expenditure, respiratory quotient and physical activity in healthy young adult cats. Methods The study was a replicated 4 × 4 complete Latin square design. Eight cats (four castrated males, four spayed females; mean age 3.0 ± 1.0 years; mean weight 4.36 ± 1.08 kg; mean body condition score 5.4 ± 1.4) were blocked by sex and body weight then randomized to treatment groups: raw policosanol (10 mg/kg body weight), encapsulated policosanol (50 mg/kg body weight), L-carnitine (200 mg/kg body weight) or no supplementation. Treatments were supplemented to a basal diet for 28 days with a 1-week washout between periods. Food was distributed equally between two offerings to ensure complete supplement consumption (first offering) and measure consumption time (second offering). Blood collection (lipid profile, complete blood count, serum biochemistry) and indirect calorimetry (energy expenditure, respiratory quotient) were conducted at days 0, 14 and 28 of each period. Activity monitors were worn 7 days prior to indirect calorimetry and blood collection. Data were analyzed using a repeated measures mixed model (SAS, v.9.4). Results Food intake and body weight were similar among treatments. There was no effect of treatment on lipid profile, serum biochemistry, activity, energy expenditure or respiratory quotient ( P >0.05); however, time to consume a second meal was greatest in cats fed raw policosanol ( P <0.05). Conclusions and relevance These data suggest that policosanol is safe for feline consumption. Further studies with cats demonstrating cardiometabolic risk factors are warranted to confirm whether policosanol therapy is an efficacious treatment for hyperlipidemia and obesity.


2011 ◽  
Vol 106 (S1) ◽  
pp. S166-S169 ◽  
Author(s):  
Ping Deng ◽  
Ryan W. Grant ◽  
Kelly S. Swanson

The prevalence of feline obesity is influenced by numerous factors, including inactivity and overconsumption of food. The objective of the present study was to evaluate the effect of feeding frequency on physical activity in adult cats. A total of twelve healthy adult cats were used in a cross-over study consisting of 32 d. In each of the two periods, six cats were fed either two meals or four meals daily. Throughout the study, cats were fed the same diet at amounts to maintain body weight and body condition score. Cats were individually housed 4 h/d at each scheduled feeding time, while for the other 20 h, cats were group-housed to allow for voluntary physical activity in the room with a 16 h light–8 h dark cycle. Voluntary activity levels were evaluated using Actical activity collars for seven consecutive days in each period. Daily average activity level for two-meal-fed cats (20·04 (sem 2·19), activity counts/epoch (15 s)) was not different from four-meal-fed cats (20·14 (sem 2·15), activity counts/epoch (15 s); P>0·05). In conclusion, when group-housed cats are fed to maintain their body weight and body condition score, varied feeding frequency between twice and four times daily may not affect activity levels.


2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Leila Shafie Bafti ◽  
Maryam Alsadat Hashemipour ◽  
Hamidreza Poureslami ◽  
Zeinab Hoseinian

The aim of the present study was to evaluate the relationship between BMI and tooth decay in a population of Iranian children. In this cross-sectional descriptive/analytical study, 1482 children were selected from kindergartens and preschool centers in Kerman, Iran. The children underwent examination of deciduous teeth (using the dmft index) after determination of height and weight for calculation of BMI. The relationship between BMI (after adjustment for age) and dmft was determined using Poisson’s regression model. The mean of dmft in children with normal BMI was 1.5-fold that in subjects with extra body weight. Age had a significant effect on dmft. In addition, dmft was higher in boys compared to girls. The results of the present study showed that caries rate in the deciduous teeth of 3–6-year-old children decreases with an increase in body weight.


2021 ◽  
Vol 31 (3) ◽  
pp. 218-226
Author(s):  
S Akter ◽  
SC Das ◽  
AS Apu ◽  
T Ahmed ◽  
A Lahiry ◽  
...  

The present study was conducted to determine the early sex in turkeys by observation of the differences in body weight between male and female birds. A total of 30-day old black color unsexed poults having almost similar body weight at hatching were considered for the experimentation and housed at the Poultry Farm of Bangladesh Agricultural University, Mymensingh-2202, Bangladesh. All birds were reared up to 12 weeks of age under intensive management with supplementation of commercial broiler starter and grower feeds. Birds were reared under similar management conditions. Significantly higher (p<0.01) body weight was attained in male poults (104g/bird) than the female (90g/bird) at the end of 1st week of age. Similarly, at the end of 2nd week of age higher (p<0.01) body weight attained by male poults (198.31g/bird) than the female (162.13g/bird). At the end of 3rd weeks of age male poults attained higher (p<0.01) body weight (307.23g/bird) than the female (251.33g/bird). After 4 weeks of rearing, male turkeys attained significantly higher (p<0.01) live body weight (424.46g/bird) than the female turkeys (347.87g/bird). The weekly average body weight gains of male and female birds were 94.18g/bird and 76.5g/bird, respectively. Thus, the male and female birds were successfully identified on the basis of differences in their body weight. Weekly feed intake for both the male and female birds was also increased with their age. Up to 4 weeks of age, both the male and female poults consumed same amount of feed (753.46g/bird). The FCR of male and female poults differed non-significantly in 1st, 3rd and 4th week. On the contrary, in 2nd week of age the FCR of male poults (1.60) was significantly lower (p<0.01) than female (2.11). Survivability was 100% up to 4th week of age irrespective of sex of the poults. The birds were reared up to 12 weeks of age until to confirm their sex by observation of the phenotypic appearance. Results of the phenotypic observation of male and female birds correspondence hundred percent accuracy with the results obtained in body weight based differences between male and female birds. It is therefore concluded that farmers can identify male or female poults as early as first week of age on the basis of body weight differences. Progressive Agriculture 31 (3): 218-226, 2020


Author(s):  
Obou Constantin Okou ◽  
Djako Sosthène Thierry Akré ◽  
Allali Eugène Koffi ◽  
Guy Childeric Bingo ◽  
Allico Joseph Djaman

The general objective of this study was to evaluate the effect of Naja nigricollis venom on some vital organs of rabbits. To carry out this study, nine (9) rabbits including five (5) males and four (4) females were divided into two (2) control lots and one (1) experimental lot. Each control lot was composed of three (3) rabbits (males or females) while the experimental lot was comprised of two (2) males and one (1) female. The rabbits of the experimental lot were injected with Naja nigricollis venom for about 20 to 30 minutes and then after the determination of their biochemical and hematological parameters, were autopsied for the removal of organs such as heart, liver, kidneys and lungs. These organs were weighed and their appearance was studied. The results of this study showed that the heart and lungs of control male rabbits weighed more than those of females, whereas the liver and kidneys did not. Then, the cytotoxins of the Naja nigricollis venom were at the origin of gangrene which induced necrosis by an increase in their volume in a general way and degradation of the organs studied. Finally, the dose of venom injected (2 mg/Kg of body weight) could also cause hypotension, so favoring the formation of oedemas and consequently gangrene.


2015 ◽  
Vol 12 (3) ◽  
pp. 31-35
Author(s):  
Natal'ya Vadimovna Anikina ◽  
Elena Nikolaevna Smirnova

Introduction. Obesity is a disorder of energy balance, which leads to excessive accumulation of fat. In recent years, many important discoveries were made in this field, including the discovery of hormones produced by adipose tissue and the identification of many of the central and peripheral pathways of energy balance.Objective. To study the levels of hormones that affect appetite and metabolism in women with obesity baseline and after weight loss while taking sibutramine.Materials and methods. The study included 56 women aged 42,9±9,5 years, with a BMI of 34,6±6,1 kg/m2. All patients underwent clinical, laboratory and instrumental examination. Hormonal study included determination of serotonin, leptin, ghrelin, endothelin-1, adiponectin.Results: In women with obesity we identified hyperleptinemia and increased serotonin levels. The decrease in body weight in patients receiving sibutramine was accompanied by lower levels of serotonin, leptin, ghrelin, endothelin-1, and increase of adiponectin.Conclusions: Obese patients have significantly elevated levels of leptin, serotonin, ghrelin compared to women of normal weight. Sibutramine treatment leads to a decrease in serotonin, leptin, ghrelin and is more effective in women with a BMI less than 36,5 kg/m2.


Sign in / Sign up

Export Citation Format

Share Document