scholarly journals ENTEROCUTANEOUS HIGH OUTPUT FISTULAE

2010 ◽  
Vol 17 (04) ◽  
pp. 538-542
Author(s):  
GHULAM MUSTAFA ARAIN ◽  
MUHAMMAD REHMAN GULZAR ◽  
KUSH MUHAMMAD SUHO ◽  
Waseem Sadiq Awan
Keyword(s):  
Enterocutaneous Fistula ◽  
Study Groups ◽  
Spontaneous Closure ◽  
P Value ◽  
Medical College ◽  
Group I ◽  
Design Case Study ◽  
High Output

Enterocutaneous fistula is an abnormal communication between epithelial lined lumen of GI tract & epithelium of an adjacent viscous or skin. Objectives: To find out role of octreotide in the management of high enterocutaneous fistula. Design: Case study. Setting: Department of Surgery Unit-II Punjab Medical College & A & E Department of Jinnah Hospital /AIMC Lahore. Period: From Jan 2007 to Dec 2008. Patients & Methods: 479 laparotomies were carried out due to trauma. Out of these 21 i.e. 4.38% developed high out put enterocutaneous fistula. All patients were put on similar conservative management including, TPN, antibiotics, fluid electrolyte replacement and stoma care. Results: Patients were split into two groups alternatively. There were no statistical difference between the study groups with regard to the age (p-value=0.515). Group I contains 11 patients (octreotide) received additionally 100mg octreotide S/C 8 hourly, showed decrease of volume from 680 to 150ml within 10 days. Spontaneous closure was observed in 8(72.72%) patient & surgery was required in 2(18.18%) patients. Death was 1(9.09%). In Group II remaining 10 patients(without octreotide), fistula discharge volume decreased form 650mg to 150ml in 20 days. Spontaneous closure was noted in 5(50%) cases. Surgery was required in 3(30%), while death rate was 2(20%).Conclusions: It is concluded that Octreotide, an analogue of somatostatin with longer half life is effective in treatment of high output fistula.

ROLE OF LIPID PROFILE IN OVARIAN CARCINOMA PATIENTS

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Dr. Manisha ◽  
Dr. Ruchi Jindal
Keyword(s):  
Ovarian Cancer ◽  
Lipid Profile ◽  
Cancer Patients ◽  
Ovarian Tumor ◽  
Ovarian Cancer Risk ◽  
Low Level ◽  
Medical College ◽  
Group I ◽  
History Of

Background: The term "ovarian cancer" includes several different types of cancer that  arise from cells of the ovary, most commonly, tumors arise from the epithelium or lining cells of the ovary.  Ovarian cancer risk is positively associated with higher consumption of dietary cholesterol and eggs, and inversely associated with a higher intake of vegetables. High consumption of fats may increase circulating estrogen levels, thus increasing the possibility of cell damage and proliferation that is responsible for cancerous growth. Material & Methods: The present study was conducted at Geetanjali Medical College and Hospital, Udaipur (Rajasthan). Total  100 cases (females) attending the obstetrics and gynecology department for some gynecological and other problem  were selected for this study between the age of 40-60 years, who were attending cancer centre at GEETANJALI MEDICAL COLLEGE AND  HOSPITAL, Udaipur (Rajasthan).                GROUP I: - It consisted of healthy females control subjects (n=50) .By routine examination and tests, we ensured that all the subjects were healthy and there were no signs and symptoms or history of ovarian tumor and diseases GROUP II: - It consisted of ovarian cancer females subjects (n=50) with a history of ovarian tumor. Results:   Higher level of cholesterol, LDL, VLDL and low level of HDL are found in ovarian cancer patients. Conclusion: The present study we highlights the importance and role of serum lipid profile in diagnosis, prognosis and recurrence of the disease. The study shows that serum level of cholesterol, LDL, VLDL was elevated in  patients of ovarian cancer while low level of HDL are found in ovarian cancer patients. Key words: lipid profile, ovarian cancer.

The Role of Nutritional Access in Malnourished Elderly Undergoing Major Surgery for Acute Abdomen: A Propensity Score-Matched Analysis

2020 ◽  
pp. 000313482097371
Author(s):  
Shekhar Gogna ◽  
David Samson ◽  
James Choi ◽  
Jorge Con ◽  
Kartik Prabhakaran ◽  
...  
Keyword(s):  
Propensity Score ◽  
Abdominal Surgery ◽  
Acute Abdomen ◽  
Anastomotic Dehiscence ◽  
The Elderly ◽  
Major Surgery ◽  
P Value ◽  
Gastrointestinal Complications ◽  
Group I

Background About 50% of the elderly undergoing emergency abdominal surgery are malnourished. The role of timely surgical nutritional access in this group of patients is unknown. Methods We analyzed the National Inpatient Sample database from 2009 through the first three-quarters of 2015 of patients aged ≥65 years who were malnourished and underwent major abdominal surgery for the acute abdomen within the first 2 days of hospital admission. Results Of 3 246 721 patients analyzed, 4311 patients met inclusion criteria. Of these, only 507 (11.8%) patients had surgical nutritional access (gastrostomy or jejunostomy) (group I), while 3804 patients (88.2%) did not (group II). In the propensity score-matched population, there were 482 patients in each group. The patients in group I had lower odds of mortality and postoperative gastrointestinal complications (paralytic ileus, anastomotic dehiscence, and intestinal fistulae) ( P-value <.01, respectively). Discussion Elderly who receive surgical nutritional access have lower rates of gastrointestinal complications and mortality.

scholarly journals Assessment and comparison of the levels of N-nitrosonornicotine and 4-(n-methyl-n –nitrosamino) -1-(3-pyridyl)-1-butanone in the saliva of tobacco chewers and non- chewers -a hospital based study

2018 ◽  
Vol 6 (2) ◽  
pp. 66
Author(s):  
Dr Harpreet Kaur Gandhoke ◽  
Dr Vasanti Lagali Jirge ◽  
Dr Anjana Bagewadi
Keyword(s):  
Statistical Analysis ◽  
Smokeless Tobacco ◽  
Statistical Difference ◽  
Study Groups ◽  
P Value ◽  
Sample Collection ◽  
Group Iii ◽  
Group I ◽  
The Mean ◽  
Tobacco Specific Nitrosamines

Background: Studies estimating the Tobacco- specific nitrosamines, (TSNA’s) which are the strongest carcinogens in the saliva oftobacco users and tobacco quitters, are limited.Objectives: To assess and compare the levels of N- nitrosamines (NNN, NNK) in the saliva of tobacco chewers and non -chewers including those who have quit the habit of tobacco use.Methods: The study included 120 patients who were divided into three groups of 40 each: Group I- Smokeless tobacco chewersGroup II- Tobacco chewers who have completely stopped the habit at least 2 weeks prior to sample collection andGroup III- non-chewers. The salivary levels of two tobacco specific nitrosamines; NNN & NNK levels were estimated in the three study groups. Statistical analysis was done by Kruskal– Wallis, one-way analysis of variance (ANOVA) test, Mann-Whitney U test. (p-value < 0.05 was considered to be statistically significant)Results: In Group I, the mean level of NNN was 651.84 ± 359.78 and mean level of NNK was 168.32 ± 131.83. In Group II, the mean level of NNN was 119.52 ± 95.05 and mean level of NNK was 42.78 ± 43.19. In Group III, the mean level of NNN was 3.44 ±6.55 and mean level of NNK was 1.98 ± 3.68. There was a statistical difference in the 3 groups with respect to mean levels of NNN and NNK.Conclusion: The study indicated that salivary tobacco-specific nitrosamines are elevated in tobacco chewers. Saliva can be used to detect TSNA’s and screen for TSNA’s during each patient’s de-addiction process.  

scholarly journals The prognostic role of inflammatory markers in COVID 19 patients – A retrospective analysis.

2021 ◽  
Author(s):  
Shivkumar Gopalakrishnan ◽  
sangeetha kandasamy ◽  
S.Malini ◽  
S.Peer Mohamed ◽  
k.velmurugan
Keyword(s):  
Inflammatory Markers ◽  
Severe Disease ◽  
Radiation Hazard ◽  
P Value ◽  
Binary Logistic Regression Analysis ◽  
Group Iii ◽  
Group I ◽  
Group Ii ◽  
D Dimer

Abstract Background. Approximately 5% of COVID-19 patients suffer near fatal disease. Clinical and radiologic features may predict severe disease albeit with limited specificity and radiation hazard. Laboratory biomarkers are eyed as simple, specific and point of care triage tools to optimize management decisions.This study aimed to study the role of inflammatory markers in prognosticating COVID-19 patients.Methodology. A hospital based retrospective study was conducted on COVID-19 adult inpatients classified into three groups as mild disease-recovered [Group I], severe disease-recovered [Group II] and dead [Group III]. Categorical outcomes were compared using Chi square test. Univariate binary logistic regression analysis was performed to test the association between the explanatory and outcome variables. Unadjusted OR along with 95% CI was calculated. The utility of lab parameters (Ferritin, LDH, D dimer, N/L ratio and PLT/L ratio) in predicting severity of COVID-19 was assessed by Receiver Operative Curve (ROC) analysis. P value < 0.05 was considered statistically significant.Results. The mean age was 49.32 +/- 17.1 years. Among study population, 378 were Group I, 66 Group II, and 56 Group III. Median levels of Ferritin among the 3 groups were 62ng/mL, 388.50 ng/mL and 1199.50 ng/mL. Median value of LDH were 95U/L, 720 and 982.50(p <0.001). D-dimer values of 3 groups were 23.20ng/mL, 104.30 ng/mL and 197.10 ng/mL (p <0.001). CRP done qualitatively was positive in 2 (0.53%), 30 (45.45%) and 53 (94.64%) of patients. The odds of patients suffering severe COVID-19 rose with rising values of ferritin, LDH and D-dimer [unadjusted OR 1.007, 1.004 &1.020]Conclusion. One time measurement of serum ferritin, LDH, D-dimer and CRP is promising to predict outcomes for COVID 19 inpatients. Single qualitative CRP was equally good but more cost effective than quantitative CRP. The most specific combination was NLR, Lymphocyte percentage and D-dimer levels done between 7th – 10th day of symptoms.

scholarly journals Chinese Paper Cutting: Opportunities for Revitalisation in Contemporary Design

2021 ◽  
Author(s):  
◽  
Jieying Huang
Keyword(s):  
Universal Access ◽  
Folk Culture ◽  
Product Packaging ◽  
The Public ◽  
Art Form ◽  
Potential Strategy ◽  
Traditional Patterns ◽  
Design Case Study

<p><b>As a result of globalised development and the rise of capitalism, the craft of traditional Chinese paper cutting is facing marginalisation. The loss of this craft has resulted in a loss of opportunities to share the valuable role of this art form: to bring good wishes to people. The revitalisation of paper cutting as a component of contemporary design offers a strategy to sustain the value and meaning of this craft.</b></p> <p>My research explores a potential strategy that supports the transformation of Chinese paper cutting in the contemporary context through its application in design practice. This research investigates the traditional patterns applied to Chinese paper cutting and their implication and symbolic meaning within Chinese folk culture. Through the development of a criteria-led design case study, this research aims to translate these concepts into the formation of new design outcomes applicable to product packaging.</p> <p>As an element of packaging design, this approach intends to take advantage of the democratisation of and universal access to this medium ensuring wide dissemination to the public.</p> <p>The purpose of this research is to translate traditional paper cutting into a contemporary design approach that enables the values of this special Chinese craft to prosper.</p>

scholarly journals Role of Tie2, CD14, Angiopoietin as Angiogenetic Markers in Hepatocellular Carcinoma Complicating Hepatitis C Virus Infection

2019 ◽  
Vol 3 (2) ◽  
pp. 23-34
Author(s):  
El-Zahraa M. Meghezel ◽  
Heba A. Ahmed ◽  
Ashraf A Askar ◽  
Emad Eldin Nabil ◽  
Ashraf Elyamany
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis C ◽  
High Risk Group ◽  
P Value ◽  
Group Iii ◽  
Group I ◽  
Angiopoietin 2 ◽  
Chronic Hepatitis C Patients ◽  
Potential Use

Background Identifying biomarkers for early detection of hepatocellular carcinoma (HCC) remains quite challenging. In this study we aimed to estimate the number of TIE2-expressing monocytes (TEMs) cells, which display pro-tumoral activities and are defined as CD14+, TIE2+, and angiopoietin-2; and its potential use as a possible diagnostic marker in HCC patients complicating HCV induced cirrhosis. Methods Current study was conducted on 112 patients. They were divided into two groups: Group I (78 patients) with HCC complicating HCV induced cirrhosis; and group II chronic hepatitis C patients (34 patients). Both groups were compared to (age and sex-matched) healthy persons as group III (38 persons). Result The number of the circulating TEMs: CD14+ and TIE2+ monocytes were significantly higher in the peripheral blood of HCC patients than HCV LC patients and healthy controls, sensitivity and specificity for HCC diagnosis were respectively: CD14 (89.7%, 83.3%), TIE 2 (76.9%, 83.3%), and Ang-2 (76.9%, 66.7%). Moreover, analysis of the P-value and the odd’s ratio showed that CD14 has the highest predictive value for HCC. Conclusion Our results suggest that TEMs and Ang-2can be used as diagnostic markers for HCC, especially among the high-risk group of patients.

scholarly journals Design for Empathy: A Co-Design Case Study with the Finnish Parliament

2019 ◽  
Vol 1 (1) ◽  
pp. 99-108
Author(s):  
Enni-Kukka S E Tuomala ◽  
Weston L Baxter
Keyword(s):  
Political Parties ◽  
Design Process ◽  
Future Research ◽  
Human Centered Design ◽  
Design Considerations ◽  
Design Case Study ◽  
Empathy Gap ◽  
Ongoing Project

AbstractGlobalisation and the mixing of people, cultures, religions and languages fuels pressing healthcare, educational, political and other complex sociocultural issues. Many of these issues are driven by society's struggle to find ways to facilitate deeper and more emotionally meaningful ways to help people connect and overcome the empathy gap which keeps various groups of people apart. This paper presents a process to design for empathy – as an outcome of design. This extends prior work which typically looks at empathy for design – as a part of the design process, as is common in inclusive design and human centered design process. We reflect on empathy in design and challenge the often internalised role of the designer to be more externalised, to shift from an empathiser to become an empathy generator. We develop and demonstrate the process to design for empathy through a co-creation case study aiming to bring empathy into politics. The ongoing project is set in the Parliament of Finland, and involves co- creation with six Members of the Parliament from five political parties. Outcomes of the process and case study are discussed, including design considerations for future research.

scholarly journals Relationship of anti-fertility effects of Andrographis paniculata and hormonal assay in female rats

1970 ◽  
pp. 10-14 ◽  
Author(s):  
S Sakila ◽  
N Begum ◽  
S Kawsar ◽  
ZA Begum ◽  
MS Zola
Keyword(s):  
Medical Science ◽  
Water Extract ◽  
Andrographis Paniculata ◽  
Female Rats ◽  
Male Rats ◽  
Control Group ◽  
Exposure Group ◽  
Medical College ◽  
Group I

Aims: This study was aimed to find out anti-fertility effects of Andrographis paniculata (AP) plant. Study design & Methodology: A prospective case control animal study with 85 female and 30 male rats (Total 115 rats) was done in the Department of Pharmacology of Dhaka Medical College and Bangladesh Medical College, Dhaka, Bangladesh from July 2002 to December 2003. The total 85 female rats were grouped into case study or exposure group (N=60 female rats) exposed to water extract of AP & control or non exposure group (N=25 female rats, 30 male rats also considered as control group) Exposure group (water extract) of female were again subdivided in 3 groups according to duration of (A.P) exposure (N=20 in each group) e.g. 4 weeks, 6 weeks and 8 weeks. Mating schedules were done after the completion of scheduled duration of exposure with A.P (Dose was 1 gm/kg). Results: In group I percentage of infertility was 33.33% in 4 weeks exposure, 50% in 6 weeks exposure & 100% in 8 weeks exposure respectively. In control group (Group II) percentage of infertility was 0%. In case study group of female rats the value of FSH was 1.20 1U/L (4 weeks), 1.12 1U/L (6 weeks), 1.00 1U/L (8 weeks), LH 0.78 1U/L (4 weeks), 0.70 1U/L (6 weeks), 0.64 1U/L (8 weeks), Estrogen 45.30 pg/ml (4 weeks), 44.80 pg/ml (6 weeks), 44.20 pg/ml (8 weeks) and Progesterone 4.84 nmol/L (4 weeks), 4.72 nmol/L (6 weeks) and 3.80 nmol/L (8 weeks). In non exposure group the value of FSH was 1.23 1U/L, LH 0.80 1U/L, Estrogen 47.05 pg/L and Progesterone 5.50 nmol/L. In exposure group all the values were lesser than the normal hormonal value. Conclusion: This study suggests that due to lower level of hormone, female rats have promising percentage of infertility with AP. Further study is needed with rat as well as clinical trial with human being. Key Words: Andrographis paniculata, Antifertility effects doi: 10.3329/bjms.v8i1.3183 Bangladesh Journal of Medical Science Vol.8 No. 1-2; 2009 10-14

scholarly journals Role of Physiotherapy in Hospitalised Patients of COVID-19 disease

2021 ◽  
Vol 9 (3) ◽  
pp. 154-159
Author(s):  
Dr. Sanjay Kumar Bharty ◽  
◽  
Dr. Jitendra Kishore Bhargava ◽  
Dr. Brahma Prakash ◽  
Dr. Vikas Patel ◽  
...  
Keyword(s):  
Severity Index ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Medical College ◽  
Breathing Exercises ◽  
Hospitalised Patients ◽  
Before And After ◽  
Respiratory Physiotherapy

Introduction: Respiratory physiotherapy is one of the therapeutic methods in various respiratoryviral infections. Breathing exercises with other interventions, could enhance the total lung capacityand symptom alleviation in patients with virus-related acute respiratory distress syndrome (ARDS).Aim: To study the clinical evaluation of the role of physiotherapy in hospitalised patients of covid-19diseases. Method: This was an Observational (prospective, cross-sectional) study. 187 patientswere recruited and diagnosed as COVID-19 as per RTPCR at NSCB Medical College, Jabalpur (MP).Patients were randomised into the physiotherapy group and controlled group. Patients in thephysiotherapy group were undergone positional changes, prone ventilation, Breathing exercise,Resistive training, Passive joint motion, Muscle stretching, Bedside standing training, enduranceexercise by a specialized physiotherapist. Mean cough severity index, MMRC grade, respiration rateand peripheral blood saturation were recorded before and after intervention and compared with thecontrolled group. Result: There was significant improvement found in MMRC grade and respirationrate after physical therapy in the physiotherapy group (p-value < 0.05). Exertional dyspnoea andcough severity index significant deceased in physiotherapy group. The positive change was found inperipheral blood saturation. There was decreased in hospitalization stay in the physiotherapy groupas compared to the controlled group. Conclusion: Our study revealed the positive effect ofphysiotherapy on covid-19 disease in terms of symptoms and hospitalization duration among thephysiotherapy group. Physiotherapy exerts a beneficial role in the management of the covid-19disease.

scholarly journals A comparison of lung function in pranayama trained and untrained medical students

2017 ◽  
Vol 5 (4) ◽  
pp. 1377
Author(s):  
Thirupathi C. ◽  
Aanandha Subramaniam K.
Keyword(s):  
Medical Students ◽  
Lung Function ◽  
Study Groups ◽  
P Value ◽  
Study Group ◽  
Breathing Exercise ◽  
Medical College ◽  
Chest Expansion ◽  
Before And After ◽  
Madras Medical College

Background: Pranayama is a form of breathing exercise. It is a very useful in reducing the weight and improving the respiratory function. The study was designed to assess the effect of pranayama on pulmonary Function among adult male students.Methods: The control and the study groups each consisted of 50 number of male MBBS students aged between 16 to 22 years, studying at Madras Medical College, were recruited for the present study. The study group were taught pranayama and allowed to practice it daily twice in morning and evening for 15 minutes for 10 weeks under supervision. Parameters like weight, BMI, chest expansion, respiratory rate and spirometric parameters like FVC, FEV1 and PEFR were recorded before and after the study.Results: A significant increase in chest expansion, FVC, FEV1 and PEFR with p value <0.05were recorded in study group in comparison with control group.Conclusions: Pranayama improves the lung function among medical students.

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