scholarly journals SENILE CATARACT PATIENTS

2015 ◽  
Vol 22 (09) ◽  
pp. 1186-1191
Author(s):  
Aniqa Mansoor ◽  
Roquyya Gul ◽  
Tayyaba Gul Malik ◽  
Muhammad Khalil ◽  
Rabail Alam
Keyword(s):  
Serum Calcium ◽  
Clinical History ◽  
Senile Cataract ◽  
Control Group ◽  
P Value ◽  
Sodium Potassium ◽  
Serum Chloride ◽  
Control Study ◽  
Cataract Patients

Purpose: The current study was aimed at finding out the significance of serumelectrolytes and serum calcium levels in the development of senile cataract. Study Design:Case control study. Setting: Ghurki Trust Teaching Hospital, Lahore, Pakistan. Period: Jan2013 to June 2013. Methods: Total fifty patients with senile cataract and fifty controls wereselected. Clinical history and clinical diagnostic tests were performed by an ophthalmologist.Blood samples were drawn and serum stored at -20o C. Serum potassium and sodiumwere measured by Flame photometry. Serum chloride levels were estimated by quantitativedisplacement of thiocyanate by chloride. The estimation of calcium was done using photometryby CPC method. Statistical analysis was done by Statistical package for social sciences (SPSSversion 16.0). There were 31 females and 19 male (F:M = 1.63:1) patients. In the control group,there were 32 females and 18 males (F:M = 1.77:1). The age was ≥ 40 years in both patientsand control group. Results: Nuclear cataract was the commonest. Among all the analytes,only serum calcium levels were found to be significantly lower in patients (p value less than0.05 as compared to controls). While difference of sodium, potassium and chloride levelsbetween cases and controls was insignificant. (p values 0.49, 0.36, and 0.45 respectively).Conclusions: In Pakistan, serum electrolytes in cataract patients are not significantly differentfrom the controls while serum Calcium of cataract patients is significantly low when comparedwith the control group, indicating the possible role of low calcium level as a risk factor in thedevelopment of senile cataract.

scholarly journals Prediction of intraperitoneal adhesions using striae gravidarum and scar characteristics in women undergoing repeated cesarean sections

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mohamed Elprince ◽  
Omima T. Taha ◽  
Zakia M. Ibrahim ◽  
Rasha E. Khamees ◽  
Mahmoud A. Greash ◽  
...  
Keyword(s):  
Scoring System ◽  
Predictive Performance ◽  
Tertiary Hospital ◽  
Control Group ◽  
P Value ◽  
Cesarean Scar ◽  
Intraperitoneal Adhesions ◽  
Almost All ◽  
Control Study

Abstract Background The current fact of increasing rates of cesarean deliveries is a catastrophe. Recurrent cesareans result in intraperitoneal adhesions that would lead to maternal morbidity during delivery. Great efforts are directed towards the prediction of intraperitoneal adhesions to provide the best care for laboring women. The aim of the current study was to evaluate the role of abdominal striae and cesarean scar characters in the prediction of intraperitoneal adhesions. Methods This was a case- control study conducted in the emergency ward of the obstetrics and gynecology department of a tertiary hospital from June to December 2019. The study was carried on patients admitted to the ward fulfilling particular inclusion and exclusion criteria. The study included two groups, group one was assessed for the presence of striae, and the degree of intraperitoneal adhesions was evaluated during the current cesarean section. Group two included patients without evidence of abdominal striae. They were evaluated for the severity of adhesions also after evaluation of the previous scar. Evaluation of the striae was done using Davey’s scoring system. The scar was assessed using the Vancouver Scar Scale. The modified Nair’s scoring system was used to evaluate intraperitoneal adhesions. Results The study group included 203 women, while the control group included 205 women. There were significant differences in the demographic characters of the recruited patients (p-value 0.001 for almost all variables). The mean Davey score in those with mild, moderate, and severe striae was 1.82 ± 0.39, 3.57 ± 0.5, and 6.73 ± 0.94, respectively (p-value < 0.001). Higher scores for the parameters of the Vancouver scale were present in patients with severe striae (1.69 ± 1.01, 1.73 ± 0.57, 2.67 ± 1.23, and 1.35 ± 1.06 for scar vascularity, pigmentation, pliability, and height respectively with a p-value of < 0.001 each). Thick intraperitoneal adhesions were noted significantly in women with severe striae [21 (43.75%), p-value < 0.001)]. The Davey’s and Vancouver scores showed highly significant predictive performance in the prediction of intraperitoneal adhesions (p-value < 0.001). Conclusion Abdominal striae and cesarean scar were significant predictors for intraperitoneal adhesions.

scholarly journals Prediction of intraperitoneal adhesions using striae gravidarum and scar characteristics in women undergoing repeated cesarean sections

2020 ◽  
Author(s):  
Mohamed Elprince ◽  
Omima Tharwat Taha ◽  
rasha khamees ◽  
khaled atwa ◽  
Ahmed gadallah ◽  
...  
Keyword(s):  
Scoring System ◽  
Predictive Performance ◽  
Tertiary Hospital ◽  
Control Group ◽  
P Value ◽  
Cesarean Scar ◽  
Intraperitoneal Adhesions ◽  
Almost All ◽  
Control Study

Abstract Background: The current fact of increasing rates of cesarean deliveries is a catastrophe. Recurrent cesareans result in intraperitoneal adhesions that would lead to maternal morbidity during delivery. Great efforts are directed towards the prediction of intraperitoneal adhesions to provide the best care for laboring women. The aim of the current study was to evaluate the role of abdominal striae and cesarean scar characters in the prediction of intraperitoneal adhesions.Methods: This was a case- control study conducted in the emergency ward of the obstetrics and gynecology department of a tertiary hospital from June to December 2019. The study was carried on patients admitted to the ward fulfilling particular inclusion and exclusion criteria. The study included two groups, group one was assessed for the presence of striae, and the degree of intraperitoneal adhesions was evaluated during the current cesarean section. Group two included patients without evidence of abdominal striae. They were evaluated for the severity of adhesions also after evaluation of the previous scar. Evaluation of the striae was done using Davey's scoring system. The scar was assessed using the Vancouver Scar Scale. The modified Nair's scoring system was used to evaluate intraperitoneal adhesions.Results: The study group included 203 women, while the control group included 205 women. There were significant differences in the demographic characters of the recruited patients (p-value 0.001 for almost all variables). The mean Davey score in those with mild, moderate, and severe striae was 1.82 ± 0.39, 3.57 ± 0.5, and 6.73 ± 0.94, respectively (p-value <0.001). Higher scores for the parameters of the Vancouver scale were present in patients with severe striae (1.69 ± 1.01, 1.73 ± 0.57, 2.67 ± 1.23, and 1.35 ± 1.06 for scar vascularity, pigmentation, pliability, and height respectively with a p-value of <0.001 each). Thick intraperitoneal adhesions were noted significantly in women with severe striae [21 (43.75%), p-value <0.001)]. The Davey's and Vancouver scores showed highly significant predictive performance in the prediction of intraperitoneal adhesions (p-value < 0.001).Conclusion: Abdominal striae and cesarean scar were significant predictors for intraperitoneal adhesions.

scholarly journals Serum calcium and phosphorus levels: a marker of disease activity in senile cataract patients

2018 ◽  
Vol 5 (2) ◽  
pp. 371
Author(s):  
Smita A. Deokar ◽  
Pooja S. K. Rai ◽  
Anita B. Rai ◽  
. Sudarshan ◽  
Shimi Sundharan ◽  
...  
Keyword(s):  
Intracellular Calcium ◽  
Serum Calcium ◽  
Serum Levels ◽  
Senile Cataract ◽  
Control Group ◽  
Phosphorus Concentration ◽  
Age Related ◽  
Calcium And Phosphorus ◽  
Cataract Patients ◽  
Phosphorus Levels

Background: The present study was aimed to study alterations in serum levels of calcium and phosphorus levels in senile cataract patients.Methods: 25 senile cataract patients in age group of 50 to 80 years and 25 control group were included in the study. Serum Calcium and Phosphorus levels were determined by Orthocresolphthalein, Fiske SubbaRow method respectivelyResults: Significantly increased levels of serum calcium in cataract patients (11.58±1.65 mg/dl) were found as compared to controls (8.53±1.45mg/dl) (p<0.0001). Serum phosphorus concentration in cataract patients (5.28±0.46 mg/dl) were significantly increased when compared to controls (3.02±1.23mg/dl) (p<0.0001).Conclusions: Presence of G-protein receptors in lens leads to the release of intracellular calcium.  As total calcium in the lens increases, we hypothesize that higher intercellular calcium concentrations, coupled with decreased Ca2+-ATPase activity and greater membrane permeability could lead to elevated free intracellular calcium levels causing cataract. So, abnormal elevation of serum calcium and phosphorus can be used as a marker for prevention of age-related human cataract.

scholarly journals A Prospective Randomised Case Control Study on the Role of Probiotics in Controlling Chronic Kidney Disease Progression

2021 ◽  
pp. 264-271
Author(s):  
A. Sai Keshava Reddy ◽  
P. Dhana Lakshmi ◽  
N. Hima Bindu ◽  
R. E. Ugandar ◽  
Y. Sai Vani
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Case Control Study ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Chronic Kidney Disease Progression ◽  
Kidney Disease Progression ◽  
Control Study

Aim:  To study the role of probiotics in controlling chronic kidney disease progression. Sample: To correlate renal parameters like creatinine, urea, uric acid, PCR in patients with chronic kidney disease. Study Design: It is a Prospective case control study Place and Duration of the Study: Department of Nephrology, Santhiram Medical college and General Hospital, between December 2020 – May 2021. Methodology: We included 150 patients with chronic kidney disease from in and out patient departments. In this study patients are divided into two groups; case and control group. Control group is treated with normal conventional therapy whereas the case group is treated with conventional therapy along with probiotics. The lab parameters like creatinine, PCR, urea, uric acid were analyzed before and after the therapy in both groups. Results: The lab parameters were analyzed by paired student`s t- test and the p value of these parameters were found to be in control group creatinine ranges from (4.42+/- 2.84 to 3.54+/- 2.73) and in case/ interventional group creatinine ranges from (5.13+/-2.43 to 2.29+/-1.57) shows <0.001. It shows significant improvement in these parameters in both control and case group. CKD stages were analyzed by Chi- square test, the p value of CKD stages in case group was found to be <0.0001 and in control group it was found to be 0.03. Conclusion: It shows that there is significant improvement is found in both interventional (case) and non-interventional (control) groups. But more betterment is observed in case group than in control group. Hence probiotics are used as a natural bio-treatment to control the progression of CKD and improves the quality of life.

scholarly journals Role of Antihelminthic Drug and Health Education in Reducing Helminthic Infestation Rate Among the Rural Children

1970 ◽  
Vol 14 (2) ◽  
pp. 70-73
Author(s):  
Md Mostaque Hossain Ansari
Keyword(s):  
Health Education ◽  
Incidence Rate ◽  
Primary Schools ◽  
Primary School Children ◽  
Control Group ◽  
P Value ◽  
Rural Children ◽  
Positive Finding ◽  
Control Study

Intestinal Helminthiasis is one of the major causes of childhood malnutrition in Bangladeshi rural children. This case control study was undertaken to observe the comparative role of antihelminthic drug and Health Education in reducing the Incidence rate of helminthic infestation in rural primary school children. Three Primary schools were selected in different union of Dhamoirhat thana in Naogaon district. Saline preparation of stool of all students in three schools were done in first week of May, August and November 1997 blindly. Tablet Mebendazole was given only to the students with positive finding of stool for helminthic ova in first school (D R School). After each examinations, health education was conducted in the second school (H E School) one hour weekly since the beginning of the study irrespective of findings and no intervention was done in the third school (C O School) taken as control group. Quarter yearly (in three months) incidence rate in D R School were 8.1% and 8.3%, in H E School were 14.5% and 23.5% and in C O School were 9.1% and 18.3% (in population at risk) in the study. Analysis shows the significant role of anti helminthic drug in reducing the incidence rate besides the prevalence than health education (P value 0.0007). Recommendation was made to continue the mass deworming program as it reduces the reservoirs despite the environmental factors sufficiently enough for transmission of the disease in Bangladesh perspective. DOI: http://dx.doi.org/10.3329/taj.v14i2.8389 TAJ 2001; 14(2): 70-73

The Estimation of prostate specific antigen (PSA) concentrations in patients with prostatitis by fully automated ELISA technique.

2020 ◽  
Vol 3 (11) ◽  
pp. 1100-1104
Author(s):  
Hussein Naeem Aldhaheri ◽  
Ihsan Edan AlSaimary ◽  
Murtadha Mohammed ALMusafer
Keyword(s):  
Personal Information ◽  
Receptor Gene ◽  
Specific Antigen ◽  
Gene Clusters ◽  
Control Group ◽  
P Value ◽  
Group Data ◽  
Elisa Technique ◽  
And Control

      The Aim of this study was to determine Immunogenetic expression of  Toll-like receptor gene clusters related to prostatitis, to give acknowledge about Role of TLR in prostatitis immunity in men from Basrah and Maysan provinces. A case–control study included 135 confirmed prostatitis patients And 50 persons as a control group. Data about age, marital status, working, infertility, family history and personal information like (Infection, Allergy, Steroid therapy, Residency, Smoking, Alcohol Drinking, Blood group, Body max index (BMI) and the clinical finding for all patients of Prostatitis were collected. This study shows the effect of PSA level in patients with prostatitis and control group, with P-value <0.0001 therefore the study shows a positive significant between elevated PSA levels and Prostatitis.

STUDY OF ROLE OF CIRCULATING ANTIOXIDANTS IN DEVELOPMENT OF SENILE CATARACT

2021 ◽  
pp. 65-70
Author(s):  
Susruta Sen ◽  
Indranil Chakraborty ◽  
Mousumi Bandyopadhyay ◽  
Indrani Pathak ◽  
Sharmistha Choudhuri
Keyword(s):  
Subsequent Development ◽  
Beta Carotene ◽  
Senile Cataract ◽  
Plasma Ascorbate ◽  
Anti Oxidant ◽  
Overnight Fasting ◽  
Total Burden ◽  
Control Study

Introduction: Senile cataract is the commonest worldwide cause of treatable blindness, most often due to excess reactive oxygen species [ROS]. Anti-oxidant vitamins namely beta-carotene, ascorbate and tocopherol and enzymes like superoxide dismutase (SOD), constitute rst line defenses against ROS assault, while malondialdehyde (MDA) levels indicate the total burden of lipid peroxidation in-vivo. Objectives: We aimed to compare the levels of above ve analytes in senile cataract patients in contrast to apparently healthy controls and also among smoking and non-smoking sub groups of both cases and controls. Methods: A hospital-based case-control study, was conducted with 102 cases of senile cataract and 102 control subjects, following strict inclusion and exclusion criteria. Recruited individuals were sub-categorized into smokers and non-smokers. After overnight fasting (12 hours), 10 ml blood was drawn aseptically. Serum and plasma were separated and used for biochemical estimations of all ve analytes, following established protocols. Levels were compared between cases and controls as well as between the smoking and non-smoking sub-sections of both groups. Results: Signicantly lower levels of plasma ascorbate and serum tocopherol were seen in cases as compared to controls (P=0.0078 and P<0.0001 respectively). Signicantly lower levels of serum beta carotene (P<0.0001), tocopherol (P<0.0001), plasma ascorbate (P<0.0001), and SOD (P<0.0001). Signicantly higher level of serum MDA (P= 0.0494) was seen in the smokers, as compared to non-smokers Conclusions: Lowered serum tocopherol and plasma ascorbate were signicant factors leading to senile cataract. Furthermore, smoking was found crucial in loss of anti-oxidant defenses and subsequent development of cataract.

scholarly journals Helicobacter pylori Infection as a Risk Factor for Hepatocellular Carcinoma: A Case-Control Study in Ethiopia

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Hailemichael Desalegn Mekonnen ◽  
Henok Fisseha ◽  
Tewodros Getinet ◽  
Fisseha Tekle ◽  
Peter R. Galle
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Case Control Study ◽  
Clinical History ◽  
Case Control ◽  
Chronic Liver ◽  
P Value ◽  
H Pylori ◽  
Control Study

Background and Aims.Hepatocellular carcinoma is a major cause of cancer death worldwide, accounting for over half a million deaths per year. Its incidence varies with geographic locations and the type of etiologic factors. In Ethiopia, unidentified causes of liver disease are of sizeable proportion. Recent studies have shown an association of H. pylori infection with different spectrums of chronic liver disease. This study was conducted at St. Paul’s Hospital Millennium Medical College in Ethiopia and assesses liver cancer and the association with H. pylori infection.Method.A prospective case-control study conducted on patients with chronic liver disease presenting with a suspicious liver lesion and diagnosed to have HCC in the Gastrointestinal (GI) Clinic of St. Paul’s Hospital MMC from Dec 30, 2016, to Nov 1, 2017 G.C. Descriptive surveys on clinical history and physical examination and laboratory profiles were obtained, and the clinical course of the patients including the type of treatment was followed prospectively. Control cases were taken from adult patients without evidence of liver disease in the internal medicine clinic coming for routine evaluation. After collection data were analyzed using SPSS version 23 and associations were assessed using chi-square test. Binary logistic regression was used to assess the association of HCC with different variables and H. pylori infection. All variables with p-value <0.05 were considered as statistically significant.Results.One hundred twenty patients were analyzed with equal representation of cases and controls. The majority of patients with HCC were male with a mean age of 36 years. Older age adjusted Odds Ratio (AOR) (95%CI, p-value) 1.07(1.03-1.09, <0.001), viral hepatitis B (AOR) (95%CI, p-value) 6.19 (1.92-19.93, 0.002), and H. pylori infection (AOR) (95%CI, p-value) 5.22 (2.04–13.31, <0.001) were statistically significantly associated with HCC.Conclusion.H. pylori infection is associated with HCC in this case-control study. This study supports the emerging evidence of H. pylori association with other extra-gastric manifestations.

scholarly journals Effect of Probiotics on Allergic Rhinitis: A Randomized, Controlled, Clinical Trial

2020 ◽  
Vol 9 ◽  
pp. 1918 ◽  
Author(s):  
Mahnaz Sadeghi-Shabestari ◽  
Yalda Jabbari Moghaddam ◽  
Hasan Rezapoor ◽  
Mojataba Sohrabpour
Keyword(s):  
Clinical Trial ◽  
Allergic Rhinitis ◽  
Standard Therapy ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
P Value ◽  
Nasal Discharge ◽  
Oral Corticosteroids ◽  
And Control

Background: Allergic rhinitis (AR) is one of the most common diseases in the world and affects about 10-50% of the general population. Probiotics are live microorganisms that help the normal state of the intestine, and if prescribed correctly, they can stimulate the mucosal immune system to prevent inflammatory symptoms of allergy and atopy. The present study aims to investigate the role of probiotics in the treatment of AR when added to standard therapy as adjuvant agents. Materials and Methods: In this clinical trial study, 28 patients older than 15 years with AR randomly divided into probiotics and control groups. The probiotics group received standard therapy for AR accompanied by probiotic capsules every 12 hours for eight weeks, whereas the control group received standard therapy for AR with placebo capsules as the same protocol. Data were analyzed using SPSS Version 23 (IBM Corporation, Armonk, NY, USA) and, the P-value less than 0.05 was considered statistically significant. Results: In the probiotics group, 14.3% of patients had sneezing at the baseline, which significantly decreased to 4.6% (P<0.01). Also, the necessity for nasal and oral corticosteroids after treatment with probiotics in the probiotics group was less than the control group (P<0.01). Although cough, nasal discharge, conchae hypertrophy, and night sleep disorders reduced after treatment with probiotics, this reduction was not statistically significant between the two groups. Conclusion: Based on the results of this clinical trial, the use of probiotics had no significant effect on the outcome of patients with AR. [GMJ.2020;9:e1918] 

scholarly journals Interaction between serum FGF-23 and PTH in renal phosphate excretion, a case-control study in hypoparathyroid patients

2019 ◽  
Author(s):  
Forough Saki ◽  
Seyed Reza Kassaee ◽  
Azita Salehifar Salehifar ◽  
gholamhossein Ranjbar omrani
Keyword(s):  
Parathyroid Hormone ◽  
Serum Calcium ◽  
Case Control Study ◽  
Fractional Excretion ◽  
Case Control ◽  
Control Group ◽  
Phosphate Excretion ◽  
Significant Difference ◽  
Fgf 23 ◽  
Control Study

Abstract Background:phosphate homeostasis is mediated through complex counter regulatory feed-back balance between parathyroid hormone, FGF-23 and 1,25(OH)2D. Both parathyroid hormone and FGF-23 regulate proximal tubular phosphate excretion through signaling on sodium- phosphate cotransporters II a and II c . However, the interaction between these hormones on phosphate excretion is not clearly understood. We performed the present study to evaluate whether the existence of sufficient parathyroid hormone is necessary for full phosphaturic function of FGF-23 or not. Methods:In this case-control study, 19 patients with hypoparathyroidism and their age- and gender-matched normal population were enrolled. Serum calcium, phosphate, alkaline phosphatase,parathyroid hormone, FGF-23, 25(OH)D, 1,25(OH)2D and Fractional excretion of phosphorous were assessed and compared between the two groups, using SPSS software. Results:The mean serum calcium and parathyroid hormone level was significantly lower in hypoparathyroid patients in comparison with the control group(P<0.001 and P<0.001, respectively). We found high serum level of phosphate and FGF-23 in hypoparathyroid patients compared to the control group (P<0.001 and P<0.001,respectively). However, there was no significant difference in Fractional excretion of phosphorous or 1,25OH2D level between the two groups. There was a positive correlation between serum FGF-23 and Fractional excretion of phosphorous just in the normal individuals (P <0.001, r = 0.79). Conclusions:Although the FGF-23 is a main regulator of urinary phosphate excretion but the existence of sufficient parathyroid hormone is necessary for the full phosphaturic effect of FGF-23.

Sign in / Sign up

Export Citation Format

Share Document