scholarly journals VIRAL MARKERS

2018 ◽  
Vol 25 (06) ◽  
pp. 903-907
Author(s):  
Mohammad Alam
Keyword(s):  
Risk Factors ◽  
Informed Consent ◽  
Blood Transfusion ◽  
Surgical Procedure ◽  
Descriptive Study ◽  
Medical Sciences ◽  
Ocular Surgery ◽  
History Of ◽  
Medical University ◽  
Barber Shops

Objectives: To know the prevalence and predisposing risk factors of HBVand HCV in patients undergoing ocular surgery. Study Design: Descriptive study. Setting:Department of Ophthalmology Khyber Medical University Institute of Medical Sciences / K.D.ATeaching Hospital Kohat. Period: January 2015 to December 2016. Materials and Methods: Alladmitted patients in eye ward for surgery. Informed consent was taken from patients. Detailedhistory including surgical, medical treatment, blood transfusion and other relevant was taken. Allthose patients who were not previously diagnosed as HBV and HCV positive were included in thestudy. ICT method was used for screening. Those who were positive with ICT were confirmed byEliza test. Eliza negative patients were excluded. During these two years total 2547 patients withmean age of 63.4 years were admitted in eye ward. Results: By ICT method 43(1.68%) patientswere HBC positive in which 24(55.81%) were male and19(44.18%) were female. 121(4.75%)patients were HCV positive, out of them 44(36.36%) were male and 77(63.63%) were female.All positive patients were confirmed by ELIZA test. Regarding predisposing risk factors. in HBVpositive, 13(30.23%) patients had history of major surgical procedure, 9(20.93%) patients haddental extraction, 6(13.95%) had blood transfusion, 6(13. 95%) had quackery injection with nondisposable syringes, 2(4.65%) patients had routine face and armpit shave in barber shops andno significant history in 7(16.27%) patients. In HCV positive, 29(23.96%) patients had history ofmajor surgical procedure, 22(18.18%) patients had blood transfusion, 18(14.87%) patients haddental extraction, 16 (13.22%) patients had history of injection by quack using non disposablesyringe, 13(10.74%)had routine face and armpit shave in barber shops and 23(19.00%) patientshad no significant history. Conclusion: HBV and HCV are common among community. HCV ismore prevalent as compared to HBV. Every patient should be screened before surgery.

Corneal Abrasion following Anaesthesia for Non-ocular Surgical Procedures: A Case-controlled Study

2017 ◽  
Vol 27 (11) ◽  
pp. 247-254 ◽  
Author(s):  
AL Carniciu ◽  
MJ Fazzari ◽  
P Tabibian ◽  
P Batta ◽  
RC Gentile ◽  
...  
Keyword(s):  
Risk Factors ◽  
New York ◽  
Surgical Procedure ◽  
Chart Review ◽  
Ocular Disease ◽  
Controlled Study ◽  
Ocular Surgery ◽  
Corneal Abrasion ◽  
Diabetes Status ◽  
History Of

The aim of this study was to identify risk factors associated with perioperative corneal abrasion at a single hospital in Mineola, New York (United States). A chart review was conducted of patients with perioperative corneal abrasion following non-ocular surgery and age-matched controls between June 2011 and November 2013. An age-stratified logistic regression model evaluated the association between corneal abrasion and potentially predisposing variables. The adjusted odds of a corneal abrasion occurring were 4.6 times greater for patients having surgery for ≥ 3 hours (p=0.001) and 3.6 times greater for patients with pre-existing ocular disease (p=0.02). Gender, diabetes status, surgical procedure or position were not found to be associated with the occurrence of a corneal abrasion. Corneal abrasions were associated with longer procedures and history of pre-existing ocular disease. No significant association between body positioning or surgical site and perioperative corneal abrasion was found. The study concludes that a longer duration of surgical procedure and pre-existing ocular disease are risk factors for perioperative corneal abrasion.

scholarly journals Risk factors for hepatitis C virus infection. A case-control study of blood donors in the Trent Region (UK)

1994 ◽  
Vol 112 (3) ◽  
pp. 595-601 ◽  
Author(s):  
K. R. Neal ◽  
D. A. Jones ◽  
D. Killey ◽  
V. James
Keyword(s):  
Risk Factors ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Blood Transfusion ◽  
Blood Donors ◽  
Case Control Study ◽  
Case Control ◽  
Hcv Infection ◽  
History Of ◽  
Control Study

SUMMARYThe introduction of screening for hepatitis C virus (HCV) by the National Blood Transfusion Service identified donors who had acquired HCV infection. We undertook a case-control study amongst blood donors in the Trent Region to determine risks for HCV infection. A total of 74 blood donors confirmed positive for hepatitis C infection and 150 age, sex and donor venue matched controls were included in the study. Fifty-three percent of hepatitis C infected blood donors reported previous use of injected drugs compared to no controls; relative risk (RR) not estimatable (lower limit 95% CI = 20). Other risk factors were a history of: receipt of a blood transfusion or blood products RR = 3·6 (95% CI 1·5–8·3), having been a ‘health care worker’ RR = 2·8 (95% CI 1·1–7·6), tattooing RR = 3·3 (95% CI 1·2–8·7), and an association with having been born abroad RR = 3·2 (95% CI 1·1–9·5). No risk was shown for a history of multiple sexual partners, ear piercing or acupuncture. Injecting drug use explains more than 50% of hepatitis C infections in blood donors, a group who are less likely to have injected drugs than the general population.

Should postoperative haemoglobin and potassium levels be checked routinely following blood-conserving primary total joint arthroplasty?

2019 ◽  
Vol 101-B (1_Supple_A) ◽  
pp. 25-31 ◽  
Author(s):  
N. J. Greco ◽  
A. G. Manocchio ◽  
A. V. Lombardi ◽  
S. L. Gao ◽  
J. Adams ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Total Joint Arthroplasty ◽  
Laboratory Data ◽  
Joint Arthroplasty ◽  
Renal Diseases ◽  
Study Cohort ◽  
Blood Conservation ◽  
Potassium Supplementation ◽  
History Of

Aims Despite declining frequency of blood transfusion and electrolyte supplementation following total joint arthroplasty, postoperative blood analyses are still routinely ordered for these patients. This study aimed to determine the rate of blood transfusion and electrolyte restoration in arthroplasty patients treated with a perioperative blood conservation protocol and to identify risk factors that would predict the need for transfusion and electrolyte supplementation. Patients and Methods Patients undergoing primary total joint arthroplasty of the hip or knee between July 2016 and February 2017 at a single institution were included in the study. Standard preoperative and postoperative laboratory data were collected and reviewed retrospectively. A uniform blood conservation programme was implemented for all patients. Need for blood transfusion or potassium supplementation was determined through a coordinated decision by the care team. Rates of transfusion and supplementation were observed, and patient risk factors were noted. Results The overall rate of blood transfusion was 1.06% in the study population of 1132 total joint arthroplasties performed in 1023 patients. Of the 12 patients requiring transfusion, 11 were female, ten occurred in patients undergoing total hip arthroplasty, and all 12 patients had a preoperative haemoglobin level less than 130 g/l. Operative duration and surgical blood loss were significantly greater in those patients requiring blood transfusion. Nearly all patients requiring transfusion had a history of, or risk factors for, cardiovascular disease. Potassium supplementation was required in 15.5% of the study cohort; 72% of these patients receiving potassium presented with a potassium level less than 4 mmol/l during preoperative testing, while the remaining 28% had a past medical history of either significant anaemia, cardiopulmonary, cardiovascular, or renal diseases that had required substantial medical management. Conclusion A consistent blood-conserving perioperative strategy effectively minimized need for blood transfusion in total joint arthroplasty patients below previously reported rates in the literature. We suggest that postoperative full blood counts and basic metabolic panels should not routinely be ordered in these patients unless their preoperative haemoglobin and potassium is below 130 g/dl or 4 mmol/l respectively, and they have medical comorbidities.

scholarly journals Clinical and endoscopic profile of patients with Mallory- Weiss tears

2017 ◽  
Vol 8 (6) ◽  
pp. 19-23
Author(s):  
Subash Bhattarai ◽  
Khus Raj Dewan ◽  
Gaurav Shrestha ◽  
Bhanumati Saikia Patowary
Keyword(s):  
Blood Transfusion ◽  
Clinical Presentation ◽  
Morbid Condition ◽  
Medical Sciences ◽  
Excessive Alcohol Consumption ◽  
Average Hospital ◽  
Endoscopic Findings ◽  
Haemodynamic Stability ◽  
History Of ◽  
Excessive Alcohol

Background: Mallory-Weiss tear is mainly located across the gastro-esophageal mucosal junction and presents with upper gastro-intestinal bleed of less severity. Haemorrhage frequently ceases spontaneously.Aims and Objective: This study was undertaken to establish the incidence, clinical and endoscopic profile of patients with Mallory- Weiss tear.Materials and Methods: Six hundred patients presenting with acute upper gastro-intestinal (UGI) bleed were included in the study. All patients underwent UGI endoscopy after achieving haemodynamic stability, usually within 24 hours. Cases with Mallory Weiss tear were identified and their clinical presentation, endoscopic findings, outcomes during hospitalization including rebleeding and mortality were studied.Results: Twenty eight (4.6%) patients out of six hundred acute upper gastro-intestinal bleed were diagnosed with Mallory-Weiss tear. Fourteen (50%) patients gave history of prior vomiting or preceeding retching. Only two patients (7.1%) presented with shock. The most common co-morbid condition was excessive alcohol consumption. Eighteen (64.3%) patients had no active bleeding during UGI endoscopy. All patients except four presented with a single tear with mean length of two cms. Blood transfusion was needed in eight (28.6%) patients only. Only one patient had re-bleeding. Average hospital admission was three days. No mortality was recorded in 7 days and 28 days of follow ups.Conclusions: Mallory-Weiss tear is not an uncommon cause of UGI bleeding nowadays and its incidence is rising every year. Hemorrhage frequently ceases spontaneously and conservative management is sufficient in many instances. When endoscopic findings reveal active haemorrhage, various endoscopic hemostatic techniques can be used.Asian Journal of Medical Sciences Vol.8(6) 2017 19-23

scholarly journals Seroprevalence and Associated Risk Factors of Hepatitis B Virus Infection Among Children in Enugu Metropolis

2018 ◽  
Vol 9 ◽  
pp. 1178122X1879285 ◽  
Author(s):  
Maryann Chinenye Ezeilo ◽  
Godwill Azeh Engwa ◽  
Romanus Ifeanyi Iroha ◽  
Damian Chukwu Odimegwu
Keyword(s):  
Risk Factors ◽  
Hepatitis B Virus ◽  
Blood Transfusion ◽  
Hepatitis B ◽  
Clinical Manifestations ◽  
Hbv Infection ◽  
Age Group ◽  
History Of Surgery ◽  
B Virus ◽  
History Of

Background: Though measures are being put in place for the management of Hepatitis B virus (HBV) infection in Nigeria, children remain the most vulnerable to develop chronic hepatitis. Routine screening in children is therefore necessary for effective control. However, the performance of the commonly used immunochromatographic test (ICT) strips has been challenging. Also, identifying the risk factors of transmission in this age group is of importance for the implementation of preventive measures. Hence, the goal of this study was to assess the test performance of the routinely used ICT strip and identify the associated clinical manifestations and risk factors of HBV. Methods: A cross sectional study involving 270 children below six years of age was conducted at ESUTH and Favor Child Pediatrics Hospital in Enugu, Nigeria. The subjects were screened for HBV by ICT and ELISA assays and a structured questionnaire was used to obtain participants data including demographic, socioeconomic, signs and symptoms, risk factors and vaccination. Results: BBased on ELISA, 31 out of 270 children were positive for HBV with an infection rate of 11.5%. ICT kit showed a low sensitivity of 51.6% in diagnosing HBV but was highly specific (100%) and accurate (94.4%). HBV infection was not associated with sex (χ2: 0.209; p = 0.401). The prevalence of HBV infection was similar in all the age group and HBV infection was not associated (χ2: 2.099; p = 0.914) with age group. All the clinical manifestations were not associated ( p > 0.05) with HBV infection. Blood transfusion, shared items, tattoo marks and history of surgery associated significantly ( p < 0.05) with HBV infections having odd ratios of 4.247, 4.224, 3.134 and 3.195 respectively. The vaccination rate was 55.2% (159/270) and only 3 (1.1%) out of 159 vaccinated subjected contracted the infection (OR: 0.068, p < 0.0001). Conclusions: HBV was prevalent (11.5%) in children below six years old in Enugu metropolis. Moreover, the routinely used ICT test was less reliable than ELISA in diagnosis HBV infection. More so, shared items, blood transfusion, tattooing and history of surgery were potential risk factors while vaccination served as a protective factor against the infection.

scholarly journals Audit of the Wheat Pill Cases at Medicolegal Clinic Mayo Hospital Lahore

2021 ◽  
pp. 86-90
Author(s):  
Kanwal Zahra ◽  
Maryam Shahid ◽  
Waqas Aslam ◽  
Usman Shahid Butt ◽  
Nida Zahra
Keyword(s):  
Intensive Care Unit ◽  
Emergency Department ◽  
Intensive Care ◽  
Mortality Rate ◽  
Age Groups ◽  
Descriptive Study ◽  
Monthly Basis ◽  
History Of ◽  
Medical University ◽  
Time Of Admission

Objective: To determine the audit of wheat pill cases at medicolegal clinic of Mayo Hospital Lahore. Materials and Methods: This descriptive study was conducted at Department of Forensic Medicine and Toxicology (medicolegal clinic), King Edward Medical University Lahore. This audit was of 9 months from September 2020 to May 2021. Patients presented at emergency department with attempt of wheat pills poisoning of all age groups and both genders were included. Cases were diagnosis via history of wheat pills consumption by the relatives. All the cases were given primary recovery and were shifted to the Intensive Care Unit (ICU). Data was collected on monthly basis form September 2020 to May 2021. All the data was collected via study proforma. Results: Total 49 wheat pill cases were observed during 9 months, their mean age was 29.26±12.68 years. Out of all 51.0% were males and 49.0% were females. Labourer males and housewives were most common 34.7% and 40.8% respectively. Frequency of wheat pill cases were high in months of September, October and May. At the time of admission 59.2% cases were seen conscious, 36.7% were semiconscious and 4.1% were unconscious. Out of all 59.2% were died. Conclusion: This study observed that the wheat pills are highly toxic with the quick and high mortality rate. Strict legislations are recommended to the sale control of these pills all over the country.

scholarly journals Associated risk factors with seroprevalence of HIV and HBV co-infection among Pregnant women attending guelendeng health District in the Mayo-kebbi East Region of Chad

2020 ◽  
Vol 6 (6) ◽  
pp. 155-160
Author(s):  
Salomon Philippe Nguwoh
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Pregnant Women ◽  
Epidemiological Data ◽  
Health District ◽  
Bivariate Analysis ◽  
Cross Sectional ◽  
East Region ◽  
History Of ◽  
Associated Risk Factors

Background: In Republic of Chad, the seroprevalence of HIV among antenatal pregnant women is known as decreasing over years meanwhile the epidemiological data among pregnant women for hepatitis B virus are scarce. The co-infection HIV/HBV increases the risk of mother to child transmission of both viruses. This study aimed to determine the rate of HIV, HBV co-infection and to identify the associated risk factors among pregnant women attending Guelendeng health district (GHD). Methods: A cross-sectional and descriptive study was conducted from March to May 2019 among pregnant women attending GHD. The questionnaire included demographics, AIDS and HBV knowledge, behavior factors and history of blood transfusion. Blood samples were obtained and tested serologically for HIV and HBV. The study of associations between exposure and outcome variables was sought with the odds ratio (OR), expressed with 95% confidence interval. Tests were performed using Epi info 7.0 with p<0.05 considered as significant. Results: Out of 200 enrolled pregnant women, the median age was 25years old with interquartile range from 20.5 to 30 years old. The seroprevalence of HIV, HBV and the co-infection HIV/HBV were 4.5% (95% CI: 2.1%-8.4%; 9/200), 13% (95% CI: 8.7%-18.5%; 26/200) and 2% (95 % IC: 0.6%-5%; 4/200) respectively. The antenatal age was associated to HBV infection (p=0.04) unlike HIV infection (p=0.4) and HIV/HBV co-infection (p=0.52). Women aged more than 29 years were most affected. Bivariate analysis identified that the non-use of condom (OR 7.79, 95% CI: 1.9-32.6, p=0.004) and blood transfusion history (OR 17.9, 95% CI: 2.6-124.8, p=0.01) were associated risk factors of contracting HIV. Conclusion: The seroprevalence of HIV and HBV remains high among pregnant women attending antenatal ward in Guelendeng Health District with associated risk factors such as age, blood transfusion and the non-use of condom with new sexual partners.

scholarly journals Seroepidemiology and associated risk factors of hepatitis B and C virus infections among pregnant women attending maternity wards at two hospitals in Swabi, Khyber Pakhtunkhwa, Pakistan

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255189
Author(s):  
Muhammad Israr ◽  
Fawad Ali ◽  
Arif Nawaz ◽  
Muhammad Idrees ◽  
Aishma Khattak ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Vertical Transmission ◽  
Educational Level ◽  
Khyber Pakhtunkhwa ◽  
History Of ◽  
Associated Risk Factors ◽  
Pregnant Mothers

Background & aim Hepatitis B and C infections are global issues that are associated with a massive financial burden in developing countries where vertical transmission is the major mode and remains high. This cross-sectional study was designed to investigate the seroepidemiology and associated risk factors of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among 375 pregnant women attending antenatal care health facilities at Bacha Khan Medical Complex (BKMC) Shahmansoor and District Head Quarter (DHQ) Hospital Swabi, Khyber Pakhtunkhwa, Pakistan. Methodology From a total of 375 pregnant women selected using systematic random sampling from both hospitals, 10 ml of blood samples were collected and alienated serum was examined for indicators identification through the Immuno-Chromatographic Test (ICT) and 3rd Generation Enzyme-Linked Immunosorbent Assay (ELISA). A pre-structured questionnaire was used to collect the socio-demographic data and possible risk factors. The data was analyzed via SPSS 23.0 statistical software. A chi-square analysis was performed to determine the association between variables. P-value < 0.05 was set statistically significant. Results The overall frequency of HBV and HCV among 375 pregnant women involved in the study was 3.7% and 2.1% respectively. None of the pregnant women were co-infected with HBV and HCV. Dental extraction (P = 0.001) and blood transfusion (P = 0.0005) were significantly allied with HBV infection while surgical procedure (P = 0.0001) was significantly associated with HCV infection. Moreover the sociodemographic characteristics: residential status (P = 0.017) and educational level (P = 0.048) were found significant risk factors of HBsAg and maternal age (P = 0.033) of anti-HCV, respectively. Conclusion & recommendation HBV and HCV infections are intermediary endemic in the study area. A higher prevalence of HBV was detected among pregnant mothers with a history of dental extraction, history of blood transfusion, resident to the urban area and low educational level. The age and surgical procedures were the potential risk factors found significantly associated with HCV positivity among pregnant mothers in our setup. Future negotiations to control vertical transmission should include routine antenatal screening for these infections early in pregnancy and the requirement of efficient preventive tools including the birth dose of the hepatitis B vaccine in combination with hepatitis B immune globulins to the neonate.

scholarly journals RISK FACTORS FOR HEPATITIS;

2018 ◽  
Vol 20 (05) ◽  
pp. 661-666
Author(s):  
MUHAMMAD ASHRAF CHAUDHRY ◽  
BUSHRA GHULAM ◽  
LAILA KHALID ◽  
Marryam Shaheen Ahmed ◽  
Amnah -
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Surgical Procedures ◽  
Public Awareness ◽  
Public Health Problem ◽  
Sampling Technique ◽  
Cross Sectional ◽  
Large Reservoir ◽  
Different Types ◽  
History Of

Background: Infections with Hepatitis B Virus (HBV) and Hepatitis C virus (HCV) are worldwide public health problem. Thisis related to the continued occurrence of new infections and the presence of a large reservoir of chronically infected persons. Objective:To determine the frequency of risk factors (causes of transmission) for HBV and HCV infections in hospitalized patients of CMH, Lahoreand Sheikh Zayed hospital, Lahore. Design: Descriptive (cross sectional). Setting: The study was carried out in CMH, Lahore and SheikhZayed hospital, Lahore from January, 2012 to July, 2012. Methods: The patients were selected by consecutive (non-probability)sampling technique. The data was collected through questionnaire. Informed written consent was obtained SPSS version 16.0 was usedto calculate the descriptive statistics. Results: Out of total of 100 subjects, 50 were cases and 50 were controls. Out of 50 cases, 26%were HBV positive and 74% were HCV positive with female preponderance. The history of injections was very high in both the groups,making a total of 64% (14% HBV; 16% HCV) the important contributors for different types of hepatitis were blood transfusion (HBV =10%; HCV = 28%; controls = 14%). Surgical procedures (4% HBV, 28% HCV; 8% controls). History of piercing in the last six months(HBV = 6%; HCV = 22% and control = 8%). History of dental procedures in the last six months was higher in HCV patients (18% HCV and4% HBV). History of HBV or HCV positive patients or relatives at home. (HBV 18%; HCV 36%; control 30%). Conclusions: In Pakistan thereis an urgent need to raise the public awareness about importance of properly screened blood transfusion, use of disposable needles andusing new blades for shaving and haircuts especially at barber shops. In our study, the important contributors for different types ofhepatitis were blood transfusion, surgical procedures and history piercing in the last 6months.

scholarly journals ACUTE MYOCARDIAL INFARCTION;

2014 ◽  
Vol 21 (06) ◽  
pp. 1200-1203
Author(s):  
Shahzad Alam Khan ◽  
Sohail Safdar ◽  
Asna Ijaz ◽  
Ijaz-Ul-Haque Taseer
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Family History ◽  
Positive Family History ◽  
Descriptive Study ◽  
Research Centre ◽  
Female Ratio ◽  
First Degree Relatives ◽  
History Of

Objective: To determine the frequency of family history of IHD and related risk factors in the first degree relatives of patients suffered from acute myocardial infarction (AMI). Study Design: Descriptive study. Setting: PMRC Research Centre, Nishtar Medical College, Multan, Cardiology unit Nishtar Hospital Multan and Chaudhry Pervez Elahi Institute of Cardiology, Multan. Duration: One year from July 2011 to June 2012. Material and methods: In this descriptive study 331 patients of AMI of either sex and age ≥ 20 years admitted in Cardiology unit of Nishtar Hospital Multan and Chaudhary Pervez Elahi Institute of Cardiology Multan were registered. For data collection non-probability convenient sampling technique was used. Informed consent was taken from each patient. The information were recorded in a pre-designed questionnaire. The data were analyzed through SPSS-11. Results: Mean age of the study cases was 54.99±11.25 years (Minimum age was 20 years and maximum was 90 years). Two hundred sixty four (79.8%) were male and 67 (20.2%) were female patients and male to female ratio was 3.9:1. Out of these 331 patients 111 (33.6 %) were having positive family history of IHD. In these 111 (33.6 %) cases history of diabetes was seen in 45 (40.5 %), 43(38.8 %) had history of hypertension and history of hyper-cholesterolemia was present in 23 (20.7 %) of cases. Conclusions: The family history of IHD in addition to traditional risk factors such as hypertension, hyperlipidemia, diabetes mellitus and smoking is itself an important risk factor for IHD. Relatives of the young patients with IHD should be considered as high risk group and it calls for close surveillance of their first degree relatives and early intervention. All their family members should be advised life style modification, appropriate management of risk factors and regular follow up of even apparently healthy descendents.

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