scholarly journals Frequency and morphology of benign histopathological lesions in total abdominal hysterectomy specimens.

2020 ◽  
Vol 27 (03) ◽  
pp. 481-486
Author(s):  
Aisha Rashid ◽  
Haniya Qamar ◽  
Saba Pario

Hysterectomy is one of the most frequently performed gynecological procedure all over the globe undertaken for varying indications, to effectively cure many gynaecological conditions. Histopathological analysis of the hysterectomy specimens should be undertaken for justification of procedure and diagnostic purposes. Objectives: To determine the frequency and morphology of different benign histopathological lesions in total abdominal hysterectomy specimens. Study Design: Descriptive cross-sectional study. Setting: Department of Pathology Fatima Jinnah Medical College. Period: From Jan 2015 to June 2015. Material & Methods:  The gross and histopathological findings of uterus and cervix in one hundred Total Abdominal hysterectomy specimens were studied. Non-probability, purposive sampling was done. Total abdominal hysterectomy specimens with or without salpingoophorectomy of patients aged between 20 to 70 years were included. While Total abdominal hysterectomy done in mentally retarded patients and for malignancies were excluded. Patient’s data, presenting complaints and preoperative diagnosis was recorded on predesigned proforma. SPSS version 17 was used as an analytical tool. Results:  Age of the patients ranged from 30-55 years with 72% between 41-50 years. The microscopic examination of the cervix revealed features of chronic cervicitis in 75% cases. The commonest neoplastic lesion was leiomyoma present in 66% of cases. Myometrium revealed foci of adenomyosis in 21% cases. Endometrial histology showed hyperplasia in 25% of cases(simple hyperplasia 20%, cystic hyperplasia 4% and complex hyperplasia 1%), hormonal imbalance in 21%, pressure atrophy in 11%, atrophic endometrium in  6% , cystic atrophy in 2% while acute and chronic endometritis in 1% and 2% of cases respectively. Conclusion: The commonest cervical lesion was chronic cervicitis (75%). The commonest benign neoplastic lesion was leiomyoma, present in 66% of cases. Other common pathologies on histology were hyperplasia in 25% of cases, adenomyosis and hormonal imbalance in 21 % of cases each, pressure atrophy in 11%, atrophic endometrium in 6% while endometritis  (acute & chronic ) in 3% of cases mainly. Histopathological examination of hysterectomy specimens helps to detect the exact cause and underlined pathology.

2018 ◽  
Vol 3 (2) ◽  
pp. 423-426
Author(s):  
Sailesh Bahadur Pradhan ◽  
Mamata Sedhain ◽  
Sneh Acharya ◽  
Sailuja Maharjan ◽  
Samikchhya Regmi

Introduction: Uterus is subjected to many non-neoplastic and neoplastic diseases. Hysterectomy is the commonest gynecological surgery done for the management of the pathologies of the female reproductive system. Histopathological examination of hysterectomy specimens is done routinely which has both diagnostic and therapeutic significance.Objective: To study the common pathologies identified in hysterectomy specimens and to correlate them with the clinical findings.Methodology: A cross sectional study was carried out among all the hysterectomy specimens irrespective of primary lesion sent for histopathological examination from January 2016 to December 2017 in Department of Pathology, Kathmandu Medical College Teaching Hospital (KMCTH). Relevant history was taken from the requisition form. Ethical clearance was obtained from the Institutional Review Committee of KMCTH.Results: A total of 198 cases were studied. The most common pathology encountered was leiomyoma (60.0%) followed by adenomyosis (14.0%). Atrophic endometrium was seen in 24.3% cases. Chronic cervicitis was found in most of the cases (96.5%) along with endocervical polyp in 8.1% cases. Leiomyoma was found to be the most common indication for hysterectomy comprising 48.0% followed by abnormal uterine bleeding (24.75%) and utero-vaginal prolapse (18.25%). Hysterectomy was most commonly performed in the age group of 41 - 50 years and total abdominal hysterectomy with bilateral salpingo-oophorectomy was found to be the commonest procedure done comprising 8 0.0%.Conclusion: Leiomyoma was found to be the most common pathology in myometrium and chronic cervicitis in cervix. Abnormal uterine bleeding and vaginal prolapsed were also found to be common. Lesions which can be managed conservatively do need hysterectomy or not, is a matter of great concern. BJHS 2018;3(2)6:423-426.


2020 ◽  
Vol 22 (4) ◽  
pp. 233-237
Author(s):  
Rakesh Pathak ◽  
M Gupta ◽  
P Poudel ◽  
K Khadka

Gall bladder is one of the important digestive organ which encountered with different histopathological changes. Different changes in dietary habit, obesity, oral contraceptives, alcohal have shows increased pattern of cholecystitis and cholelithiasis and other pathological findings. Detail examination of gall bladder in cholecystectomy specimen helps to evaluate different histopathological pattern of gall bladder lesion and also help to differentiate non-neoplastic from neoplastic lesion and also helps in further management. This was a cross sectional study done in the Department of Pathology, Nepal Medical College Teaching Hospital, Kathmandu, Nepal, during the study of period of six months (Feburary 2020 to July 2020). A total of 127 patients between 16 years to 63 years with mean age of 40.54±10.88 years. There were 127 cholecystectomy specimens were received during study period and out of which 94 were female and 33 were male. On histopathologial evaluation, chronic cholecystitis was most common findings followed by chronic cholecystitis with cholesterolosis. Other findings were chronic cholecystitis with adenomyosis, chronic cholecystitis with pyloric metplasia, chronic cholecystitis with intestinal metpalsia, chronic cholecystitis with polyp, acute on chronic cholecystitis, Xanthogranulomatous cholecytsitis and adenocarcarcinoma . Median age was 40.54 years. It was concluded that Chronic cholecystitis was the most common histopathologcial findings and the common groups was 41-50 years. Routine examination of cholecystectomy specimens grossly and microscopically is important for patient management Though a very few cases of carcinoma of Gall bladder is seen, it is very important to make sure that all cholecystectomy specimens undergone histopathological examination, with this, we can achieve timely diagnosis and early managements.


2020 ◽  
Vol 27 (02) ◽  
pp. 217-224 ◽  
Author(s):  
Sarosh Khan ◽  
Sheema Khan ◽  
Shehla Raza Channa ◽  
Muhammad Adnan Bawany

Objectives: To determine the frequency and severity of depression and anxiety in patients who had undergone total abdominal hysterectomy with bilateral salpingo-oophorectomy. Study Design: A cross-sectional study. Setting: Department of Obstetrics and Gynecology, Isra University Hospital, Hyderabad, Sindh. Period: From 14th January 2015 to 14th January 2016. Material & Methods: Total 136 women were included in the study that had undergone total abdominal hysterectomy along with bilateral salpingo-oophorectomy. Women who had an obstetrical hysterectomy, vaginal hysterectomy, subtotal hysterectomy, hysterectomized women with pre-existing depression and psychosis and women who did not agree to participate were excluded. Anxiety and depression were labelled along with severity as per operational definition using Zung self-rating depression and Zung self-rating anxiety scale and were analyzed by using SPSS 11.0. Result: Majority of the women were married (88.2%), educated (66.9%), and grand multiparous (46.3%). Commonest age group was more than 40 years (29.4%). Anxiety was present in 27.2% whereas depression was seen in 32.4% women. Conclusion: There was a highly significant association of age, parity and level of education with anxiety as well as depression. Majority of the women suffered from mild to moderate level of anxiety and depression.


2020 ◽  
Vol 27 (02) ◽  
pp. 217-224
Author(s):  
Sarosh Khan ◽  
Sheema Khan ◽  
Shehla Raza Channa ◽  
Muhammad Adnan Bawany

Objectives: To determine the frequency and severity of depression and anxiety in patients who had undergone total abdominal hysterectomy with bilateral salpingo-oophorectomy. Study Design: A cross-sectional study. Setting: Department of Obstetrics and Gynecology, Isra University Hospital, Hyderabad, Sindh. Period: From 14th January 2015 to 14th January 2016. Material & Methods: Total 136 women were included in the study that had undergone total abdominal hysterectomy along with bilateral salpingo-oophorectomy. Women who had an obstetrical hysterectomy, vaginal hysterectomy, subtotal hysterectomy, hysterectomized women with pre-existing depression and psychosis and women who did not agree to participate were excluded. Anxiety and depression were labelled along with severity as per operational definition using Zung self-rating depression and Zung self-rating anxiety scale and were analyzed by using SPSS 11.0. Result: Majority of the women were married (88.2%), educated (66.9%), and grand multiparous (46.3%). Commonest age group was more than 40 years (29.4%). Anxiety was present in 27.2% whereas depression was seen in 32.4% women. Conclusion: There was a highly significant association of age, parity and level of education with anxiety as well as depression. Majority of the women suffered from mild to moderate level of anxiety and depression.


Author(s):  
Hetal Kirit Shah ◽  
Suryakant Dongre ◽  
Ravindra Karle

Background: Central nervous system (CNS) lesions show considerable geographic and racial variations with respect to the incidence and their pattern of distribution. CNS neoplasm account for 2% of all cancers. There has been a rapid increase in incidence of CNS tumors. Many non-neoplastic CNS lesions can clinically and radiologically mimic brain tumors and to differentiate them histopathological examination is necessary.Methods: This was a descriptive cross-sectional study of 30 cases, carried out from March 2020 to February 2021, in a tertiary health care hospital. The cases were diagnosed histopathologically and categorized according to the WHO 2021 classification.Results: The study included 30 cases. 3 (10%) of them were non-neoplastic while 27 (90%) were neoplastic with glioblastoma and diffuse astrocytoma being the most common. Overall, tumors of neuroepithelial tissue (60%) was the most common entity. Frontal lobe was the most commonly observed site in the neoplastic lesion. Headache was the most common presentation. Age range varied from 7 years to 66 years with the mean age of 32.7 years.Conclusions: The spectrum of neoplastic lesions were astrocytoma, glioblastoma, ependymoma, hemagioblastoma, medulloblastoma, meningioma, non-hodgkins lymphoma, oligodendroglioma, pitutary adenoma, schwannoma and non-neoplastic were A-V malformation, brain abscess, subdural empyema.


Author(s):  
Dharmpal Godara ◽  
Vijay Pal Singh Dhayal

Background: The present study highlights the occurrence of Incidental gallbladder carcinoma (IGBC) detected during histopathological examination in cholecystectomy specimens removed for cholelithiasis. Methods- This is a tertiary hospital based cross-sectional study of 500 cholecystectomy specimens removed during cholelithiasis. Relevant hospital records, histopathology slides and reports were reviewed, re-evaluated and studied. Results: 4(0.80%) cases of incidental gall bladder carcinoma (IGBC) were diagnosed from the histopathological evaluation (HPE) of 500 cholecystectomy specimens, constituting 0.80% of gall bladder specimens received during the study period. The age of the patients with IGBC ranged from 51-80 years. More females were affected than males with a M:F ratio of 1:3. Conclusion: Early detection of IGBC by histopathological examination would have a favourable impact on prognosis and management thereby increasing the survival outcome. Keywords: Cholelithiasis, Incidental Gall Bladder Carcinoma


1970 ◽  
Vol 17 (2) ◽  
pp. 88-93
Author(s):  
K Ahsan ◽  
MZ Hossain ◽  
MR Uddin

Context: A cross-sectional study was carried out at the Department of Pathology, Dhaka Medical Collage, Dhaka and Immunology Laboratory, Laboratory Sciences Division of ICDDR,B, Dhaka during a period of 1 year from July, 2007 to June, 2008 to determine the efficacy of endoscopic crush cytology in the detection of Helicobacter pylori infection in gastroduodenal diseases. Clinically suspected cases of gastro-duodenal lesions and who had not taken antibiotics, omeprazole or bismuth salts for at least three weeks prior to endoscopy were selected. Patients who were clinically and endoscopically suspected of having malignancy were excluded from the study. A total of 110 such subjects were consecutively included in the study. The statistics used to analyze the data were descriptive statistics and components of accuracy test.Results: The sensitivity of crush cytology in correctly diagnosing H. pylori of those who had the disease was 89.3%, while the specificity of the test in correctly differentiating those who did not have H. pylori was 92.6% when compared against histopathological examination using Giemsa stain. However, a slightly low sensitivity (86.2%) without compromising with specificity (92.3%) was obtained when the crush cytology diagnosis was compared against histopathological examination using haematoxylin-eosin (H & E) stain.Conclusion: The study concludes that the diagnostic accuracy of crush smear cytology (sensitivity and specificity) for detection of Helicobacter pylori in gastric biopsy material is comparable to histopathology. Moreover, the technique is very simple, less expensive and less time consuming which gives clinicians added advantage in making a quicker decision.Key words: Cytology; Helicobacter pylori; Gastroduodenal disease. DOI: 10.3329/jdmc.v17i2.6589J Dhaka Med Coll. 2008; 17(2) : 88-93


2013 ◽  
Vol 5 (1) ◽  
pp. 11-13
Author(s):  
Mst Syeeda Showkat ◽  
Lubna Khondker ◽  
Shahryar Nabi ◽  
Bishwajit Bhowmik

Background: Transvaginal sonography is superior to transabdominal sonography in most cases of pelvic pathology. Objective: This study was undertaken to see the clinicalpathological characteristics of endometrial hyperplasia. Methodology: This cross sectional study was carried out from January 2007 to December 2008 for a period of two years. All suspected cases of endometrial hyperplasia were included for this study. Transvaginal sonography (TVS) performed and confirmation was done by histopathological examination. Result: A total number of 40 cases were enrolled for this study. The most common diagnosed endometrial pathology was endometrial hyperplasia which was 42.5% cases. Endometrial polyp was diagnosed in 32.5% cases. Endometrial carcinoma was in 7.5% patients and submucosal fibroid was in 10.0%. Conclusion: Endometrial hyperplasia is the most common disease among the women presented with endometrial pathology. DOI: http://dx.doi.org/10.3329/jssmc.v5i1.16198 J Shaheed Suhrawardy Med Coll, 2013;5(1):11-13


2008 ◽  
Vol 15 (04) ◽  
pp. 486-491
Author(s):  
MUHAMMAD IKRAM ◽  
ZOONA SAEED ◽  
ROOHI SAEED ◽  
Uhammad Saeed

Objective: To evaluate abdominal versus vaginal hysterectomy in relation to operative and post operative complications.Design: Single centre cross sectional study. Place and duration: The Department of Obstetric and Gynaecology, Shaikh Zayed post graduateMedical institute and Hospital, Lahore from 1 November 2005 to 31 October 2006. Subject and methods: All the patients with benign st stindications for hysterectomy (abdominal and vaginal) were included except patients with serious / complicated medical disease. Relativeinformations were filled in a Performa and informations were taken from case records. Results: This audit report included 200 women. 23.3%patients of vaginal hysterectomy were in the age group of 40-45 years while 35.7%patients of abdominal hysterectomy were in the age of 51-55years. Main indication for abdominal hysterectomy (85.5%) was fibroid uterus while for vaginal hysterectomy (66.6%) was Uterovaginal prolapse.Most common immediate post operative complication in abdominal and vaginal hysterectomy was fever in 42.8% and 20.0% respectively.Intraoperative visceral injuries were done in 4 patients in abdominal hysterectomy while no injury was done in vaginal hysterectomy. 44(80%)patients of vaginal hysterectomy were discharged with in 7 days of hospitalization while 64 (44%) patients of abdominal hysterectomy weredischarged with in 7 days of hospitalization. Conclusion: Hysterectomy either abdominal or vaginal is very safe and there were no lethalcomplication except few minor complications and also there was no mortality.


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