Histopathological Evaluation of Gall Bladder In Cholecystectomy Specimens in a Tertiary Health Care Centre of Nepal

2020 ◽  
Vol 22 (4) ◽  
pp. 233-237
Author(s):  
Rakesh Pathak ◽  
M Gupta ◽  
P Poudel ◽  
K Khadka
Keyword(s):  
Gall Bladder ◽  
Histopathological Examination ◽  
College Teaching ◽  
Cross Sectional Study ◽  
Chronic Cholecystitis ◽  
Dietary Habit ◽  
Health Care Centre ◽  
Cross Sectional ◽  
Medical College ◽  
Neoplastic Lesion

Gall bladder is one of the important digestive organ which encountered with different histopathological changes. Different changes in dietary habit, obesity, oral contraceptives, alcohal have shows increased pattern of cholecystitis and cholelithiasis and other pathological findings. Detail examination of gall bladder in cholecystectomy specimen helps to evaluate different histopathological pattern of gall bladder lesion and also help to differentiate non-neoplastic from neoplastic lesion and also helps in further management. This was a cross sectional study done in the Department of Pathology, Nepal Medical College Teaching Hospital, Kathmandu, Nepal, during the study of period of six months (Feburary 2020 to July 2020). A total of 127 patients between 16 years to 63 years with mean age of 40.54±10.88 years. There were 127 cholecystectomy specimens were received during study period and out of which 94 were female and 33 were male. On histopathologial evaluation, chronic cholecystitis was most common findings followed by chronic cholecystitis with cholesterolosis. Other findings were chronic cholecystitis with adenomyosis, chronic cholecystitis with pyloric metplasia, chronic cholecystitis with intestinal metpalsia, chronic cholecystitis with polyp, acute on chronic cholecystitis, Xanthogranulomatous cholecytsitis and adenocarcarcinoma . Median age was 40.54 years. It was concluded that Chronic cholecystitis was the most common histopathologcial findings and the common groups was 41-50 years. Routine examination of cholecystectomy specimens grossly and microscopically is important for patient management Though a very few cases of carcinoma of Gall bladder is seen, it is very important to make sure that all cholecystectomy specimens undergone histopathological examination, with this, we can achieve timely diagnosis and early managements.

INCIDENTAL GALL BLADDER CARCINOMA (IGBC) IN CHOLECYSTECTOMY SPECIMENS REMOVED FOR CHOLELITHIASIS

2021 ◽  
Vol 5 (10) ◽  
Author(s):  
Dharmpal Godara ◽  
Vijay Pal Singh Dhayal
Keyword(s):  
Gall Bladder ◽  
Bladder Carcinoma ◽  
Histopathological Examination ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Survival Outcome ◽  
Sectional Study ◽  
Gall Bladder Carcinoma ◽  
Cross Sectional ◽  
Hospital Records

Background: The present study highlights the occurrence of Incidental gallbladder carcinoma (IGBC) detected during histopathological examination in cholecystectomy specimens removed for cholelithiasis. Methods- This is a tertiary hospital based cross-sectional study of 500 cholecystectomy specimens removed during cholelithiasis. Relevant hospital records, histopathology slides and reports were reviewed, re-evaluated and studied. Results: 4(0.80%) cases of incidental gall bladder carcinoma (IGBC) were diagnosed from the histopathological evaluation (HPE) of 500 cholecystectomy specimens, constituting 0.80% of gall bladder specimens received during the study period. The age of the patients with IGBC ranged from 51-80 years. More females were affected than males with a M:F ratio of 1:3. Conclusion: Early detection of IGBC by histopathological examination would have a favourable impact on prognosis and management thereby increasing the survival outcome. Keywords: Cholelithiasis, Incidental Gall Bladder Carcinoma

Knowledge, Attitude and Practices of Pharmacovigilance among Doctors at a Tertiary Care Teaching Hospital Birgunj, Nepal

Med Phoenix ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 14-18
Author(s):  
Smita Singh ◽  
Deependra Prasad Sarraf ◽  
Prabin Singh ◽  
Pragati Poudyel
Keyword(s):  
Teaching Hospital ◽  
Health Care Professionals ◽  
Tertiary Care ◽  
College Teaching ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Medical College ◽  
National Medical

Introduction: Pharmacovigilance helps in the detection and prevention of adverse effects of drugs. For the effectiveness of this program, health care professionals should report adverse drug reactions (ADRs) considering it as their moral and professional obligation. The objective of the study was to assess the knowledge, attitude, and practices (KAP) of the doctors towards ADRs and pharmacovigilance in  National Medical College Teaching Hospital (NMCTH), a tertiary care teaching hospital situated in the Narayani zone. Materials and Methods: A cross-sectional study was carried out using a self-administered questionnaire consisting of four parts; first part included a demographic profile of participants, the second part consisted of ten questions for the assessment of the knowledge about pharmacovigilance, third part comprised of six questions on attitude and fourth part consisted of five questions on practice. The results were depicted in the form of percentages for each KAPs questionnaire.   Results: The response rate of participants was 85.16%. Pharmacovigilance was correctly defined by 52%. Department of drug administration was responsible for monitoring ADRs in Nepal was correctly given by 80%. Only 8% had reported ADRs, although 62% had encountered an ADR in their clinical practice. Conclusion: The doctors at NMCTH had a poor KAP towards pharmacovigilance and educational intervention is needed for the proper functioning of this program.

scholarly journals Knowledge of Pressure Ulcer Management among Nurses

2017 ◽  
Vol 9 (2) ◽  
pp. 47-51 ◽  
Author(s):  
Nisha Shrestha ◽  
P Shrestha
Keyword(s):  
Pressure Ulcer ◽  
College Teaching ◽  
Cross Sectional Study ◽  
Current Evidence ◽  
Chi Square ◽  
Cross Sectional ◽  
Medical College ◽  
Adequate Knowledge ◽  
Chi Square Test ◽  
Experience Education

Background: Pressure ulcer (PU) development remains a significant complication among at-risk patients. It is considered “never events” because they are preventable and should “never” happen. It has been associated with increased morbidity, mortality, hospital cost and length of stay in the hospital. Prevention of pressure ulcers is considered a nurse-sensitive indicator hence nurses should have adequate knowledge about current evidence-based prevention and management of pressure ulcer. However, non adherence to these guidelines is frequent and lack of knowledge may act as barriers to using guidelines in clinical practice.Objectives: The objectives of the study were to 1. assess the knowledge of pressure ulcer management among nurses 2. determine the level of knowledge of pressure ulcer management among nurses 3. assess the association of knowledge of nurses and baseline variables.Methods: A descriptive cross sectional study was conducted, using pretested self administered questionnaire to assess the knowledge on pressure ulcer management among purposively selected 100 nurses working in Gandaki Medical College Teaching Hospital in 2015. Descriptive statistics as frequency and percentage were used and inferential statistics (Chi-square test) was done to find out association between knowledge and selected baseline variables.Results: The study revealed that 59% of the respondents had adequate knowledge where as 41% of nurse’s knowledge was found to be inadequate. Significant association was not found between age, working ward, experience, education, training, duration and knowledge of pressure ulcer management among Nurses.Conclusion: This result indicates that more than half of the nurses had the adequate knowledge but there is still need of education and training related pressure ulcer management.Journal of Gandaki Medical CollegeVolume, 09, Number 2, July December  2016, Page: 47-51

scholarly journals Routine Histopathological Examination After Cholecystectomy

KYAMC Journal ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 184-187
Author(s):  
Md Abu Bakar Siddiue ◽  
Firoz Mahmud ◽  
M Fardil Hossain Faisal ◽  
Md Fazlur Rahman ◽  
Bidhan C Das ◽  
...  
Keyword(s):  
Observational Study ◽  
Gall Bladder ◽  
General Surgery ◽  
Histopathological Examination ◽  
Chronic Cholecystitis ◽  
Common Finding ◽  
Neoplastic Lesion ◽  
Medical University ◽  
Malignant Condition ◽  
Macroscopic Examination

Background: Cholecystectomy is one of the commonest surgeries in medical practice. Sometimes malignant condition cannot be assessed pre-operatively. Histopathology require for tissue diagnosis. Objective: To assess whether the histopathogical examination is really needed for all bladder specimens resected for cholelithiasis and cholecystitis. Materials and Methods: This observational study was carried out in the General Surgery Unit, Department of Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka from May, 2016 to April, 2017. A total number of 95 patients were included in this study. Results: Total of 95 gallbladder specimens were submitted for histopathological examination where 33.7% were males and 66.3 % were females with mean age of 46+12.86 years. Chronic cholecystitis was the most common finding in 91.6% of cases whereas Xanthogranulomatous 2.1%. Six of the gall bladders showed adenocarcinoma (6.3%), of which four had changes on ultrasound and macroscopic gall bladder analysis (MGAS) disturbances were found in 5 cases and 1 case was found incidentally on histopathological examination. On ultrasound, only four (66.66%) and peroperative macroscopic examination by surgeon only 5(83.3%) had a clue of carcinoma. Conclusion: It could be concluded that , routine histopathological examination of gallbladder after cholecystectomy is necessary as USG sometimes can not differentiate neoplastic lesion from inflammatory one. KYAMC Journal Vol. 10, No.-4, January 2020, Page 184-187

scholarly journals A study of gastrointestinal tumors at kathmandu medical college teaching hospital

2018 ◽  
Vol 8 (1) ◽  
pp. 1285-1288
Author(s):  
Sailesh Bahadur Pradhan ◽  
Binita Pradhan ◽  
Sailuja Maharjan ◽  
Prabin Bikram Thapa
Keyword(s):  
Gastrointestinal Tract ◽  
Teaching Hospital ◽  
Histopathological Examination ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
College Teaching ◽  
Age Group ◽  
Benign Lesions ◽  
Cross Sectional ◽  
Medical College

Background: Gastrointestinal tract tumour is responsible for more cancers and death than any other cancers.  The tumour in GIT include the tumour of the Oral cavity, Esophagus, Stomach, Colon, Rectum, Liver, Gallbladder, Pancreas and Biliary tree.Materials and methods: A cross sectional study was carried out among all the gastrointestinal tract tumours specimens received for histopathological examination in between January 2016 to June 2017 in Department of Pathology, Kathmandu Medical College Teaching Hospital. All tumors diagnosed either benign or malignant were included in this study. Ethical clearance was obtained from the Institutional Review Committee in KMCTH.Results: Colorectum was found to be the most commonly involved site for malignant lesion comprising 40.2% among all malignant lesions followed by stomach comprising 28.6%. Malignancy was found to be more prevalent among male with M:F ratio of 1.6:1 in colorectal region and 1.4:1 in stomach cancers. Regarding benign lesions (polyps), rectum was found to be the commonest site (57.5%), followed by colon (20.0%) and stomach, the least common site.Malignant lesions were more common among the age group of 51-60 years (37.66%) with 70.13% above 50 years. Benign lesions were also found to be the most common above 50 years comprising 40.0 percent.Conclusion: Rectum & colon was found to be the most commonly involved site for both malignant and benign lesion. Malignancy is more prevalent among male and common above 50 years of age. However, malignant cases noted in the adult age group are a matter of great concern.

scholarly journals Incidence of filariasis in clinically diagnosed primary vaginal hydrocele

2020 ◽  
Vol 7 (3) ◽  
pp. 640
Author(s):  
Mahendra Bendre ◽  
Shrreya Akhil ◽  
Srujan Kondreddy
Keyword(s):  
Histopathological Examination ◽  
Peripheral Blood Smear ◽  
Cross Sectional Study ◽  
Research Centre ◽  
Bancroftian Filariasis ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Filarial Antigen ◽  
Circulating Filarial Antigen

Background: Lymphatic filariasis is caused by a mosquito-borne parasite affecting roughly 100 million people round the world. There is consensus that hydrocele is the most frequent clinical manifestation of bancroftian filariasis. In endemic areas, about 40% of men are suffering from testicular hydrocele. With this background, the present study was aimed to find the incidence of filariasis in clinically diagnosed primary vaginal hydrocele.Methods: A hospital based prospective, cross-sectional study was conducted with 60 patients diagnosed clinically as primary vaginal hydrocele coming to the department of surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, to assess the incidence of filariasis.Results: Anti-filarial antibody and circulating filarial antigen in serum were detected in 5 (8.3%). Out of 60 patients and anti-filarial antibody was detected in hydrocele fluid of 2 (3.3%) patients. 2 patients out of these 5 showed microfilaria in peripheral blood smear and eosinophilic infiltrates in histopathological examination of sac.Conclusions: In 5 out of 60 cases both anti-filarial antibody and circulating filarial antigen in serum are positive thus proving that incidence of filarial hydrocele is 8% in clinically diagnosed primary vaginal hydrocele which is supposed to be idiopathic. Even though these cases have presented as clinically primary vaginal hydrocele, they are found to be filarial hydrocele after analysis of serum and hydrocele fluid. So, it is advised that all cases of clinically diagnosed primary vaginal hydroceles should be investigated for filariasis and if not, may lead to recurrence in these cases.

scholarly journals Knowledge of Vitamin D among First-year Medical Undergraduate Students of a Medical College: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (235) ◽  
Author(s):  
Pratibha Manandhar ◽  
Naresh Manandhar ◽  
Sunil Kumar Joshi
Keyword(s):  
Vitamin D ◽  
Undergraduate Students ◽  
College Teaching ◽  
Cross Sectional Study ◽  
First Year ◽  
Undergraduate Medical Students ◽  
Cross Sectional ◽  
Medical College ◽  
Medical Undergraduate ◽  
Medical Undergraduate Students

Introduction: Vitamin D also known as the sunshine vitamin, helps in bone metabolism and calcium homeostasis. It is estimated that one billion people in the world have vitamin D deficiency making it a public health problem. The objective of this study is to find out the knowledge regarding vitamin D among first-year medical undergraduate students of a medical college. Methods: This is a descriptive cross-sectional study carried out from 2nd February 2020 to 15th February 2020 at Kathmandu Medical College Teaching Hospital, Duwakot among medical undergraduate students of a medical college. Ethical clearance was received from the Institutional Review Committee of Kathmandu Medical College Teaching Hospital (Reference Number: 2812201809). A structured self-designed multiple-choice questionnaire on vitamin D knowledge was used. Convenient sampling method was applied and statistical analysis was done with Statistical Package for the Social Sciences 20 version. Results: Out of total 157 undergraduate medical students, 21 (13.3%) exhibited good knowledge, 116 (73.9.8%) had average, and 20 (12.8%) had poor knowledge. There were 83 (52.9%) Bachelor of Medicine and Bachelor of Surgery students, 39 (24.8%) were Bachelor of Dental Surgery and 35 (22.3%) were Nursing students. Conclusions: We found a satisfactory level of knowledge of vitamin D among first-year undergraduate medical students of a medical college when compared to similar studies. The majority of students from all three disciplines had average knowledge of vitamin D.

scholarly journals A Pattern of Age-related Macular Degeneration

2009 ◽  
Vol 48 (175) ◽  
Author(s):  
Suprada Pokhrel ◽  
O K Malla ◽  
C L Pradhananga ◽  
S N Joshi
Keyword(s):  
Macular Degeneration ◽  
College Teaching ◽  
Female Gender ◽  
Cross Sectional Study ◽  
Age Related Macular Degeneration ◽  
Cross Sectional ◽  
Medical College ◽  
Age Related ◽  
Increased Risk ◽  
Number Of Individuals

Introduction: Age related macular degeneration is a disorder of the macula most often clinicallyapparent affecting central vision and is one of the leading causes of blindness in the populationabove 50 years. The aim of this study is to determine clinical profi le of AMD in Nepalese presentingto a Teaching Hospital in Kathmandu.Methods: It was a hospital-based cross-sectional study. The subjects included in the study were thosepresenting to the Ophthalmology department of Kathmandu Medical College Teaching Hospitalfrom July 2007- Dec 2007.The total number of individuals included in the study were 402 and totalnumber of eyes were 804.Results: AMD was observed in 5.2% out of 402 subjects of 40 years and above age group withprevalence increasing with age. The prevalence of AMD was 0.7% within 40-50 years of age-groupindividuals increasing to 2.6% in 51-60 years, 6.5% in 61-70 years and to 19.3% among subjectsabove 71 years. This study revealed that the prevalence of AMD in females was higher with femalepreponderance in ratio of 2.5:1. 52.5 % AMD subjects in our study had visual impairment with 6/24-6/60 vision and 15% had vision <3/60-PL. Our study revealed statistically signifi cant increased riskfor AMD with aging (p=0.00). Increased risk was observed in female gender and diabetics though theOdds ratio (OR) was statistically insignifi cant (p=>0.01).Conclusions: Prevalence of AMD in Nepalese presenting to Kathmandu Medical College TeachingHospital was 5% with female preponderance in ratio of 2.5:1. Aging showed statistically signifi cantincreased risk for AMD development in this study.Key Words: Age-related macular degeneration, blindness, Nepalese, prevalence

scholarly journals Clinical Profiles of Hepatocellular Carcinoma Patients: Experience of 50 cases in Dhaka City

2017 ◽  
Vol 14 (2) ◽  
pp. 36-39
Author(s):  
Md. Akter Hossain ◽  
Md. Saiful Islam ◽  
Md. Abdullah Yusuf
Keyword(s):  
Hepatocellular Carcinoma ◽  
Histopathological Examination ◽  
Cross Sectional Study ◽  
Age Group ◽  
Cross Sectional ◽  
Medical College ◽  
Clinical Profiles ◽  
Upper Abdominal ◽  
Medical University ◽  
Patients Experience

Background: The clinical characteristics of hepatocellular carcinoma are varied from person to person.Objectives: The purpose of the present study was to see the clinical profiles of hepatocellular carcinoma patients.Methodology: This cross sectional study was carried out in the Department of Radiology and Imaging in Dhaka Medical College, Dhaka and Banghabandhu Sheikh Mujib Medical University, Dhaka from January 2007 to May 2008 for a period of around one and half year. All the patients presented with hepatocellular carcinoma at the age group of more than 20 years with both sexes were selected as study population. The patients were undergone CT-scan examination and the confirmation was performed by histopathological examination. All the clinical features of HCC patients were recorded.Result: A total number of 50 patients were recruited in this study after fulfilling the inclusion and exclusion criteria. Mean age of my study was 48.78 and SD ± 12.07. Hepatocellular carcinoma commonly presented with hepatomegaly (96%). Upper abdominal pain (60%), weight loss (60%), anorexia (44%), nausea/vomiting (44%), bruit (21%), jaundice (40%) and ascitis (32%) was also present.Conclusion: In conclusion the hepatocellular carcinoma is most commonly occurred in middle age group with a predominance of male.Journal of Science Foundation 2016;14(2):36-39

scholarly journals Pattern of superficial venous arrangement in cubital fossa among preclinical Nepalese MBBS students at Birat Medical College Teaching Hospital

2021 ◽  
Vol 12 (10) ◽  
pp. 152-156
Author(s):  
Sanjib Kumar Sah ◽  
Sidarth Timsinha ◽  
Raju Kumar Chaudhary ◽  
Rajesh Kumar Shah ◽  
Umesh Kumar Mehta
Keyword(s):  
College Teaching ◽  
Venous Access ◽  
Cross Sectional Study ◽  
Type I ◽  
Cross Sectional ◽  
Medical College ◽  
Significant Difference ◽  
Reconstructive Microsurgery ◽  
Cubital Fossa ◽  
The Right

Background: The superficial veins of the cubital fossa are frequently variable in existence and arrangement. Many clinical procedures, such as reconstructive microsurgery and arterial bypass surgery, as well as intravenous injections or therapy, require the use of superficial veins. Aims and Objective: The aim of the study was to observe and describe the variations in anatomical distribution of the superficial veins of the cubital fossa in Nepalese pre-clinical medical students. Materials and Methods: The cross-sectional study included a total of 98 students between 18 to 24 years of age. A total of 196 anterior aspects of both arms were examined for cubital venous pattern. A tourniquet was applied at the mid-arm and drawing of the pattern of veins was made on a separate unglazed paper. The venous patterns in the cubital fossa were then categorized based on their gender. Results: Six patterns of superficial veins of the cubital fossa were observed. The commonest pattern in both genders was type I pattern. No statistical significant difference was observed between patterns of superficial veins on the right and left cubital fossa (P = 0.728 and 0.825 respectively) in both male and female subjects. Conclusion: Our research showed six venous patterns of superficial veins at the cubital fossa in Nepalese population. Understanding the common anatomy, patterns and variations of superficial vein anastomosis is imperative as this knowledge would help those needing venous access for various medical procedures.

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