scholarly journals Studies on development of early immunity against type O FMD in naturally susceptible animals

2020 ◽  
pp. 94-101
Author(s):  
D. V. Mikhalishin ◽  
D. A. Lozovoy ◽  
V. A. Starikov ◽  
Yu. S. El’kina ◽  
M. I. Doronin ◽  
...  

FMD risk in the Russian Federation dictates the need for enhanced measures aiming to prevent the introduction of FMD virus and comprising systematic monitoring research and mass vaccination of susceptible animals in the buffer zone. Research into the development of vaccines for early protection confirm that their use induces the formation of virus-neutralizing antibodies in naturally susceptible animals in the outbreak area, which protects from FMD infection, limits its spread and contains it within the primary outbreak. Taking into account the high speed of the infection spread, such a control measure as using FMD vaccines which induce early protection should be adopted immediately after the occurrence of the outbreak. The article presents the results of the research into the formation of humoral immunity in naturally susceptible animals triggered by administration of inactivated emulsion FMD vaccines capable of ensuring early protection against type O FMD. Culture FMD virus of О/Primorsky/2012, О/Saudi Arabia/08 and О/Mongolia/2017 strains was used for vaccine production. Immunogenic activity of vaccines was tested in cattle, pigs, and sheep. It was found that monovalent emulsion FMD vaccine based on О/Mongolia/2017 strain induced the formation of virus-neutralizing antibodies in the quantity necessary to protect against the homologous strain in seven days after a single administration in the dose of 2 cm3 . Vaccines based on О/Saudi Arabia/08 and О/Primorsky/2012 FMDV strains can protect animals from infection with heterologous О/Mongolia/2017 strain at early stages if a double dose is administered. Vaccines based on the above-mentioned strains induce early immunity formation (seven days after vaccination) against type O FMD. We suggest using the given products in the zones of a higher risk of the virus introduction.

2019 ◽  
Vol 265 ◽  
pp. 02016
Author(s):  
Vladimir Karetnikov ◽  
Sergey Rudykh ◽  
Aleksandra Ivanova

Survey works on inland waterways can be contingently divided into two directions. The first ones are directed at maintaining the given dimensions of the waterway and are carried out with the use of technical fleet vessels, which includes the dredging fleet. At the same time the basis creation, the results verification and the control of the survey works implementation are carried out by the survey party. The main types of work here are surveying and trawling works, the implementation of which is carried out at the present time on the inland waterways of Russia using geo information technologies, which makes it possible to improve the quality and efficiency of their realization. Such an approach, firstly, has a positive effect on the implementation of the navigational hydrographic support system of navigators, including in the part of electronic cartography, and secondly, it allows to provide the survey works realization at the modern level. The most effective approaches and methods of modern geo information technologies application, implemented for the collection and processing of high-precision bathymetric information and positioning data to ensure the navigation safety on the inland waterways of the Russian Federation, are considered in the paper.


Author(s):  
O.V. Shinkareva ◽  
V.A. Dikikh

The article is devoted to the analysis of the types of control measures that will be carried out in accordance with Federal Law No. 248-FZ of the “On State Control (Supervision) and Municipal Control in the Russian Federation”, the main provisions of which will enter into force on July 1, 2021. This law also applies to the activities of organizations that are subject to licensing. Types of control (supervisory) measures are considered, in particular, control and monitoring procurement, inspection visit, raid inspection, documentary and field inspection, as well as monitoring compliance with mandatory requirements and field examination. The essence of each type of control measure, the basis for carrying out the measures, control actions that can be used in their implementation are analyzed.


Author(s):  
А.М. САЖНЕВ ◽  
Л.Г. РОГУЛИНА

Приводятся результаты моделирования сверхскоростного буфера тактовых сигналов, выполненного на базе арсенид-галлиевых n-канальных транзисторов в среде OrCAD и полностью отвечающего следующим требованиям: высокие технические характеристики, малые размеры, высокая частота и КПД, гибкость применения. Приведенные поведенческие модели допускают использование любой программной среды по схемотехническому моделированию. The results of simulation of an ultra-high-speed clock signal buffer based on gallium arsenide n-channel transistors in OrCAD are presented, which fully meets the following requirements: high technical characteristics, application flexibility, low cost, small size, high frequency, and high efficiency. The given behavioral models allow the use of any software environment for circuit modeling.


Author(s):  
Anna Aleksandrovna Bakulina

This article explores the vulnerabilities of Russia in the digital environment, as well as such phenomena of modern digital economy as cryptocurrencies, blockchain, big data, artificial intelligence, and robotics. The question is raised on the risks that humanity faces in the digital space, which entail the implementation of the latest technologies in society. The author offers the ways for their minimization. The article covers the project “Digital Economy” developed by the Government of the Russian Federation, which is intended for creation of sustainable and secure information and telecommunications infrastructure for high-speed transmission, processing and storage of data bulk, accessible to all organizations and households. Analysis is conducted on the modern enterprise in the sphere of information and communication technologies and the concept on the protection against personal data theft. The crucial role of the IT specialists in digitalization is highlighted. The conclusion is made that in digital space, the major threat to national security is the hacker attacks aimed at the theft of personal data, intellectual property, etc. The author believes that the minimization of risks detected in the course of research requires providing technology opportunity for the Russian Federation to store the collected data locally, rather than abroad. The all-round government influence on the research and legislative sphere, legislative orientation towards stimulating the development of innovation technologies would ensure safe and effective integration of socioeconomic sphere into the digital space.


2012 ◽  
Vol 12 (2) ◽  
pp. 215-220
Author(s):  
T. Szymczak

The Structure of the Silumin Coat on Alloy Cast Steels The work presents the analysis results of the structure of the coat obtained by dipping in silumin AlSi5 of two grades of alloy cast steel: GX6CrNiTi18-10 (LH18N9T) and GX39Cr13 (LH14). The temperature of the silumin bath was 750±5°C, and the hold-up time of the cast steel element τ = 180 s. The absolute thickness of the coat obtained in the given conditions was g = 104 μm on cast steel GX6CrNiTi18-10 and g = 132 μm on GX39Cr13. The obtained coat consisted of three layers of different phase structure. The first layer from the base "g1" was constructed of the phase AlFe including Si and alloy additives of the tested cast steel grades: Cr and Ni (GX6CrNiTi18-10) and Cr (GX39Cr13). The second layer "g1" of intermetallic phases AlFe which also contains Si and Cr crystallizes on it. The last, external layer "g2" of the coat consists of the silumin containing the intermetallic phases AlFeSi which additionally can contain alloy additives of the cast steel. It was shown that there were no carbides on the coat of the tested cast steels which are the component of their microstructure, as it took place in the case of the coat on the high speed steels.


Author(s):  
Ivan Vladimirovich Pashchenko ◽  
Vladislav Vitalevich Kozlov ◽  
Andrei Igorevich Sokolov

The article discusses communication facilities for transmitting corrections and ephemeris data, analyzes methods of calculating errors of satellite position finding, and gives results of field tests for determining accuracy of the location for Real Time Kinematic and Precise Point Positioning modes. There has been carried out a survey of the existing functioning differential satellite subsystems, satellite differential correction and monitoring systems. The methods of differential coordinate correction currently used on the inland water transport provide accuracy within 1-5 meters. As in the unmanned mode the given accuracy is not sufficient, there appears the need to develop methods for calculating location finding with centimeter precision. Precise positioning relative to the axis of the ship's course will make it possible to control the vessel in the unmanned mode, as well as to use robotic facilities on water transport capable of making safe voyages on a set of waypoints tied to geographical coordinates.


2015 ◽  
Vol 18 (2) ◽  
pp. 112-128 ◽  
Author(s):  
Olaf Zawacki-Richter ◽  
Yasar Kondakci ◽  
Svenja Bedenlier ◽  
Uthman Alturki ◽  
Ahmed Aldraiweesh ◽  
...  

Abstract In many countries, open and distance education is perceived as a way to meet the growing need for higher education. This paper explores the development of online and distance education in three countries that are still a white spot on the landscape of international distance education research although they have implemented elaborated distance education systems: Turkey, Russia and Saudi-Arabia. In order to understand the current state of distance education systems in the three countries, their respective systems are described from a historical perspective, compared in regard to their organization, important institutions for open and distance education and current developments. This comparative analysis directs the focus on little investigated education systems and contributes to an enhanced understanding of their past, present, and future.


2020 ◽  
Vol 6 (2) ◽  
pp. 5-19
Author(s):  
Elena M. Volkova

The article reviews the world experience in the construction and operation of high-speed railways in terms of factors that determine the success or failure of such projects. Since the construction of HSR is often considered as a part of national projects on a broader scale, it is proposed to use as criteria for success not only commercial indicators, but also various socio-economic effects arising from their implementation. The author classifies externalities that reflect the impact of HSR on the development of regions and cities and presents the results of foreign research on their quantitative and qualitative analysis. Special attention is paid to the experience of China, since this country significantly differs from the rest of the world in terms of development of high-speed rail traffic. In this regard, the largest amount of representative data that allows us to identify the success factors of HSR projects can be found for Chinese projects. The main scientific result of this article is a generalization of the existing experience of HSR construction projects and justification of the prospects for implementing such projects in the Russian Federation.


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