scholarly journals ANALYSIS OF COMPLIANCE WITH THE REQUIREMENTS OF GOOD PHARMACY PRACTICE FOR PHARMACEUTICAL CONSULTINGWHEN CHOOSING OTC DRUGS ON THE WEBSITES OF ONLINE PHARMACIES

2021 ◽  
Vol 8 (3) ◽  
pp. 14-21
Author(s):  
I.E. Lukoianova ◽  
S.N. Egorova
Keyword(s):  
Pharmacy Practice ◽  
The State ◽  
Medical Attention ◽  
Medicinal Products ◽  
Self Medication ◽  
Anal Ysis ◽  
Otc Drugs ◽  
State Register ◽  
Industry Standard ◽  
Online Pharmacy

Purpose of the study: to analyze the current state of Internet pharmacy websites in terms of compliance with Good Pharmacy Prac- tice requirements for pharmaceutical counseling for OTC-medicines. Methods. The study used the method of content analysis; a search was carried out in the search engines Google and Yandex for the keywords, «buy a pharmacy», «a drug store to buy a drug», «online pharmacy». TOP 25 pharma- cy websites were subjected to logical, comparative and structural analysis. The study consisted of 2 stages: an anal- ysis of the requirements of regulatory documents for pharmaceutical consulting when selling OTC drugs and an as- sessment of pharmacy websites in terms of ensuring compliance with these requirements when carrying out online commerce. Results. Studies of online pharmacy websites showed that most of the sites did not fully comply with the regulated require- ments: a pharmaceutical license is presented on 80% of sites, information on the type of pharmacy organization, on the impossibility of returning and exchanging pharmacy goods - on 76% of sites. The choice of OTC drugs based on symptoms within the framework of responsible self-medication was available on 24% of Internet pharmacy sites, but there were no indications of symptoms requiring immediate medical attention. Links to the State Register of Maximum Selling Prices were available on 8% of Internet pharmacy sites. Conclusion. Comparative analysis of information requirements in relation to pharmaceutical consulting in a pharmacy, reg- ulated by Orders of the Ministry of Health of Russia No. 80 «On approval of the Industry standard» Rules for the dispensing (sale) of medicines in pharmacies. Basic provisions «and No. 647n dated 31.08.2016» On approval of the Rules Good Pharma- cy Practice of Medicinal Products for Medical Use ”, Government Decree No. 697 of May 16, 2020“ On Approval of the Rules for Issuing Permits for Remote Retail Sale of Medicinal Products for Medical Use, Implementation of Such Trade ... ”, showed that most of the requirements for offline pharmacy were reflected in relation to Internet pharmacies, however, as a result of the analysis of Internet pharmacy websites, it was found that these requirements are not fully met. Additional criteria for evaluating online pharmacy sites corresponding to the level of pharmaceutical care in an offline pharmacy are proposed: the ability to select an OTC drug by symptoms within the framework of responsible self-medication, the presence of indications of symptoms that require immediate medical attention, the presence of instructions for the medical use of the drug in in ac- cordance with the State Register of Medicines, ensuring access to the State Register of maximum selling prices, availability of information on the actual shelf life of the medicinal products being sold.

OVERVIEW OF THE MARKET OF THE REPUBLIC OF KAZAKHSTAN FOR LIQUID MEDICINAL PRODUCTS WITH EXPECTORANT ACTION

2021 ◽  
pp. 49-53
Author(s):  
К. МУТАЛИМОВА ◽  
К.А. ЖАПАРКУЛОВА
Keyword(s):  
Medicinal Plants ◽  
Medical Devices ◽  
Plant Extracts ◽  
The State ◽  
Herbal Preparation ◽  
Medicinal Products ◽  
State Register ◽  
The Republic

В данной статье приведены актуальности лекарственных препаратов для перорального применения на основе растительных экстрактов, в частности лекарственных растений Чабреца ползучего и Фиалка трехцветной, также обзор Государственного реестра лекарственных средств и медицинских изделий Республики Казахстан по жидким лекарственным препаратам на основе фитосубстанции This article provides an overview of the relevance of medicinal products for oral use based on plant extracts, in particular medicinal plants Creeping Thyme and Violа tricolor, as well as an overview of the State Register of Medicines and Medical Devices of the Republic of Kazakhstan for liquid medicinal products based on phytosubstance (herbal preparation)

ALFALFA VARIETIES ZONED IN THE CENTRAL CHERNOZEM ZONE OF THE RUSSIAN FEDERATION

2020 ◽  
Author(s):  
Galina Stepanova
Keyword(s):  
Medicago Sativa ◽  
Dry Matter ◽  
Maximum Yield ◽  
The State ◽  
Average Yield ◽  
State Register ◽  
Independent Evaluation ◽  
Medicago Sativa L ◽  
Alfalfa Varieties ◽  
Central Chernozem

The article describes the main morphological and biological features of alfalfa varieties included in the State register of breeding achievements approved for use in the Central Chernozem zone of Russia. A total of 32 alfalfa varieties are included in the State register. This is 9 varieties of blue alfalfa (Medicago sativa L. subsp. Sativa) of domestic selection and 8 foreign, 11 varieties of variable alfalfa (Medicago sativa L. nothosubsp. varia (Martyn) Arcang.) domestic selection and 1 variety of foreign and 3 varieties of yellow alfalfa (Medicago sativa L. subsp. falcata (L.) Arcang.). It shows the average and maximum yield of varieties determined in the process of state variety testing, as well as independent evaluation in research institutions in the region. Varieties of blue alfalfa of domestic selection Kevsala, Elena, Satellite, Vavilovskaya Yubileynaya were the most productive. The average yield of dry matter of these varieties reaches 8.4–9.2 t/ha, the maximum — 15.3–17.7 t/ha. Alfalfa varieties Timbale and Galaxy were the most productive among foreign varieties: the average yield of dry matter was 8.1 and 8.3 t/ha, the maximum – 15.5 and 17.2 t/ha. Varieties of alfalfa variable Vitalina and Vela provided an average yield of dry matter of 7.6 and 9.0 t/ha, the maximum yield reached 15.4 and 18.1 t/ha.

The issue of radioactive contamination in context of ecosystem services development

2016 ◽  
Vol 3 (3) ◽  
pp. 48-53 ◽  
Author(s):  
G. Chobotko ◽  
L. Raychuk ◽  
I. McDonald
Keyword(s):  
Ecosystem Services ◽  
The State ◽  
Natural Ecosystems ◽  
Type Region ◽  
State Register ◽  
Agrarian Policy ◽  
Literary Sources ◽  
Radiation Contamination ◽  
Logical Research

The aim of the article was to defi ne the role of the radioactive environment contamination in the formation of ecosystem services strategy. Methods. Monographic, systemic and structural, factor analysis, abstract and logical research methods have been used. The data from the State Statistics Service of Ukraine, the Ministry of Agrarian Policy and Food of Ukraine, the Ministry of Ecology and Natural Resources of Ukraine, materials of scientifi c researches, international materials and reports and other literary sources on the issues investigated have been used as an information base. Results. Retrospective analysis of sources and state of radioactive eco- systems contamination was conducted and the priority steps in developing the concept of ecosystem services in conditions of radiation contamination were found. Conclusions. The current socio-ecological paradigm of the transition from environmental use to environmental management should be refl ected in the relevant envi- ronmental management mechanisms. Currently, when assessing the state of ecosystem services in Ukraine and worldwide one must take into account the changes in food demand of residents of radioactively contaminated areas, the exploitation of radioactively safe ecosystems growth, their overload and degradation. All of this re- quires an inventory of ecosystem services by type, region, consumers, etc. and the formation of a state register of ecosystem services with a clear assignment of area of responsibility for appropriate natural ecosystems. This will help to make the economic evaluation of different ecosystem services and mechanisms of charges for ecosystem services.

Селекция и семеноводство картофеля в Камчатском крае

2018 ◽  
Author(s):  
N.I. Ryakhovskaya ◽  
T.P. Sherstyukova ◽  
M.L. Gamolina
Keyword(s):  
Russian Federation ◽  
Potato Yield ◽  
The State ◽  
Limiting Factors ◽  
State Register ◽  
Region Selection ◽  
New Varieties ◽  
The Russian Federation ◽  
Selection Of

Рассмотрены агроклиматические условия Камчатского края и лимитирующие факторы, сдерживающие рост урожайности картофеля. Приведены характеристики новых сортов картофеля селекции Камчатского НИИСХ созданных в соответствии с приоритетными для региона направлениями селекции, включенных в Государственный реестр селекционных достижений РФ и охраняемых патентами.Agroclimatic conditions of the Kamchatka Krai and limiting factors that restrain the growth of potato yield are considered. The characteristics of new varieties of potatoes of the selection of the Kamchatsky RIA are created in accordance with the priority for the region selection areas included in the State Register of Selection Achievements of the Russian Federation and protected by patents.

Breeding study of sea buckthorn (Hippophae rhamnoides L.) in the Institute of Horticulture, NAAS оf Ukraine

2020 ◽  
pp. 37-49
Author(s):  
V.V. Moskalets ◽  
◽  
T.Z. Moskalets ◽  
I.V. Grynyk ◽  
O.A. Shevchuk ◽  
...  
Keyword(s):  
Genetic Markers ◽  
Cell Biology ◽  
Molecular Genetic ◽  
The State ◽  
Sea Buckthorn ◽  
National Academy Of Sciences ◽  
Scientific Cooperation ◽  
State Register ◽  
Academy Of Sciences

The authors present the results of the sea buckthorn breeding at the Institute of Horticulture (NAAS). The stages of the work have been analyzed – from studying and selecting the initial material in the conditions of the Polissya, Polissya-Lisosteppe and Lisosteppe ecotopes (2012-2016) to the successful targeted introduction to the Northern part of the Lisosteppe (2017-2019) and new forms have been characterized according to the traits valuable for economy and molec-ular genetic markers. The new forms of the researched crop taking into consideration the high indices of their productiv-ity,adaptivity to the unfavourable abiotic and biotic environmental factors and consumption quality of fruits for pro-cessing and making functionary products were entered officially into Genetic Fund of the Plants of Ukraine as con-firmed by the certificates of copyright and developed genetic passports. The list of these genotypes includes 1-15-1 (Nos-ivchanka, UA3700073), 1-15-8S (Mitsna, UA3700079), make form 1-15-6Ch (Aboryhen 6/11, UA3700080), 1-15-9 Ka-rotynna, UA3700082), 1-15-3 (Pamiatka, UA3700076), 1-15-8V (Soniachne siayvo, UA3700075), 1-15-11 (Lymonna, UA3700072), 2-15-73 (Morkviana, UA3700077), 1-15-5 (Adaptyvna, UA3700078), 1-15-8B (Osoblyva, UA3700083), 1-15-6 (Apelsynova, UA3700084) and forms 6A/11 (UA3700081), 1-15-5a (Sribnolysta 5a, UA3700074). The possibility of using 5 DNA markers to characterize genotypes of sea buckthorn bymeans of the molecular genetic markers was tested and evaluated in the framework of the scientific cooperation with the Institute of Cell Biology and Genetic Engineering of the National Academy of Sciences of Ukraine. It should be noted that the most polymorphic markers were HrMS025 and HrMS026. However, the marker HrMS014 was monomorphic, but appeared in all the samples, so it can be used as a reference. The best forms of sea buckthorn Adaptyvna (certificate №190899) and Osoblyva (certificate №190900) were included into the State Register of Plant Varieties Suitable for dissemination in Ukraine, and the cultivars of the univer-sal use Nadiina (applications №18299010), Oliana (applications №18299009) and Morkviana (applications № 20299001) and cv pollinator Obrii (applications №18299008) undergo the State strain test. The attention is concentrat-ed on the promising directions of the new sea buckthorn genotypes for the prior breeding and genetic investigations at the Institute of Horticulture (NAAS) and its network.

Evaluation of collection accessions of fodder grasses for economical traits

2018 ◽  
pp. 54-65
Author(s):  
L.Z. Baistruk-Hlodan ◽  
M.M. Khomiak ◽  
G.Z. Zhapaleu ◽  
G.L. Koval
Keyword(s):  
Gene Pool ◽  
Red Clover ◽  
The State ◽  
Initial Material ◽  
Forage Grasses ◽  
Economic Traits ◽  
State Register ◽  
Carpathian Region ◽  
Resource Collection ◽  
Fodder Grasses

The goal was to include new accessions of perennial leguminous and cereal grasses to the collection, to evaluate them in terms of a set of valuable morphological and economic features and to identify sources of these features for breeding.Results and discussion. The collections of gene pool accessions created due to introduction of cultivars and wild forms as well as breeding accessions identified during practical breeding serve as initial material for the breeding of red clover, alsike clover and cock's-foot in the Institute of Agriculture of the Carpathian Region. For the period of 2000-2017, 944 accessions of forage grasses registered in the Central Database were included in the collection: 405 legumes (red clover – 161, alsike clover – 11) and 539 cereals (cock's-foot – 145); 591 accessions were stored in the National Depository. In-depth studies of morphological and economic traits of the accessions allowed us to create and to register a basic collection of the forage grasses gene pool, a trait collection of red clover for yield and resistance to powdery mildew (it includes 52 accessions from 5 countries), a trait collection of cock's-foot for yield and resistance to unfavorable factors (49 accessions from 8 countries) and to register valuable red clover accession No. 193 and cock's-foot accession Drogobychanka Piznia with the NCPGRU. Based on the collection accessions, varieties were created and included in the State Register of Plant Varieties Suitable for Dissemination in Ukraine: red clover Truskavchanka since 2016, alsike clover Prydnistrovska since 2002, cock's-foot Marichka since 2014. Since 2015, red clover variety Ukrainochka and cock's-foot variety Boikivchanka have been tested in the state scientific expert evaluation.Conclusions. The creation of the genetic resource collection allowed us to study and analyze the genetic potential of the species, to identify initial material with valuable economical traits, which will significantly increase the efficiency of fodder grasses breeding.

scholarly journals Assessment of health seeking behaviour and self-medication among general public in the state of Penang, Malaysia

2017 ◽  
Vol 15 (3) ◽  
pp. 991-991 ◽  
Author(s):  
Omar T. Dawood ◽  
Mohamed A. Hassali ◽  
Fahad Saleem ◽  
Inas R. Ibrahim ◽  
Aseel H. Abdulameer ◽  
...  
Keyword(s):  
General Public ◽  
The State ◽  
Health Seeking Behaviour ◽  
Health Seeking ◽  
Self Medication

Bronchodilator and anti-inflammatory therapy of chronic obstructive pulmonary disease from the position of interchangeability

2021 ◽  
Vol 31 (4) ◽  
pp. 518-529
Author(s):  
E. A. Orlova ◽  
I. P. Dorfman ◽  
M. A. Orlov ◽  
A. K. Andreeva ◽  
M. A. Abdullaev
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Generic Drugs ◽  
The State ◽  
Chronic Obstructive ◽  
Anticholinergic Drugs ◽  
Adherence To Treatment ◽  
Obstructive Pulmonary Disease ◽  
State Register ◽  
Anti Inflammatory

The choice of drugs used to treat patients with chronic obstructive pulmonary disease (COPD) (inhaled β-agonists, M-anticholinergic drugs, inhaled corticosteroids (ICS)) in view of their interchangeability is reviewed in this article. This aspect is especially important for clinicians when choosing an effective and safe treatment for COPD and for increasing patient adherence to treatment.The aim of this study was to assess the ratio of the number of reference (original), interchangeable, and generic drugs used in COPD.Methods. In accordance with the Russian clinical guidelines 2018 and GOLD 2019, modern drugs for the treatment of COPD with bronchodilator and anti-inflammatory activity were selected. All trade names of the corresponding drugs for each international non-proprietary name (INN) In the State Register of Medicines website were considered. The information on the availability of reference (original) drugs and the corresponding interchangeable products, as well as their presence in the List of vital and essential drugs was analyzed.Results. A large number of generic prodcuts are registered in the State Register of Medicines, and only a few of them are interchangeable with the corresponding reference (original) drug.Conclusion. The analysis will help widen the doctors’ choice of interchangeable drugs in treatment of COPD with an equivalent effect and safety of reference drugs, as well as to increase the patients’ adherence to treatment.

scholarly journals Influence of increasing doses of nitrogen on feed productivity of perennial grasses

2019 ◽  
pp. 19-24
Author(s):  
Svetlana Vasil'evna Ivanova ◽  
Olga Vasil'evna Kurdakova ◽  
Aminat Msostovna Konova ◽  
Anna Yurievna Gavrilova
Keyword(s):  
Dry Matter ◽  
The State ◽  
Perennial Grasses ◽  
Nitrogen Fertilizers ◽  
First Year ◽  
Yield Increase ◽  
Green Mass ◽  
State Register ◽  
Second Year ◽  
First Year Of Life

In the course of the experiment, the effect of increasing doses of nitrogen fertilizers on the yield of clover of the meadow variety Nadezhny, entered in the State Register of Breeding Achievements in 2012, was analyzed. A comparison is also made of this influence with the timothy of the meadow variety Leningradskaya 204. It was established that the pre-sowing introduction of mineral nitrogen for clover and timothy has influenced the productivity of these crops, but the nature of this effect varies depending on the type of grass. The introduction of N20 against the background of P30K90, which provided an increase in control of 51.2% for green mass and 33.6% for air-dry matter, was optimal for meadow clover of the first year of life. For grassland clover second year of life, the best option was N0P30K90, which gave an increase of 56.6% to the control on green mass and 50.6% on air-dry matter. A further increase in the dose of nitrogen on the options caused a decrease in yield increase. Timothy meadow for two years of life was traced responsiveness to the provision of nitrogen. The most productive in all respects was the option N120P30K90.    

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