Positive influence of symbiotic probiotics on the immune system, intestinal microflora and the weight gain of pigs

2020 ◽  
Vol 23 (03) ◽  
pp. 48-51
Author(s):  
N.N. Zabashta ◽  
◽  
E.N. Golovko ◽  
E.A. Moskalenko ◽  
E.P. Lisovitskaya ◽  
...  
2020 ◽  
Vol 14 (1) ◽  
pp. 1-8
Author(s):  
Vladimir Ivashkin ◽  
Maria Fadeeva ◽  
Manana Skhirtladze ◽  
Oxana Zolnikova

In this review, we have considered and discussed the existing data to achieve a deeper understanding of the role of intestinal microbiota in the development and progression of chronic heart failure (CHF). The key moments of the CHF pathogenesis (an imbalance of neurohumoral systems, inflammatory theory and metabolic disorders) and the respective changes of the intestinal microflora composition were compared. Here, we also present the latest results of the positive influence of the microflora modulations on the course and prognosis of CHF with the prescribing antibiotics, probiotics and prebiotics.


10.12737/7744 ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. 124-127
Author(s):  
Самоделкин ◽  
Aleksandr Samodelkin ◽  
Еремин ◽  
Sergey Eremin

There was studied the distribution of postpartum pathology of cows and disease of calves in early postnatal period in conditions of Nizhny Novgorod region. It was established, that the new tissue drug "bio-tec" has positive influence on reproductive function, safety and live weight gain of calves. The postpartum pathology of cows gained wide spread among nizhnynovgorod farms up to 80%, e.g. Endometritis and subinvolution of uterus 37,4 and 23,9 respectively. By clinical examination of newborn calves it was established, that in the first month of life 50,3% fall ill with gastrointestinal diseases of various etiologies. The die-off of calves reached 29%. Using "bio-tec" drug to dry cows decreased the percentage of postpartum pathology by 35% and reduced the time of involution of uterus for 11,2 days; the service period reduced by 21,2 days and the diseases of newborn calves was twice less, that increased the energy of growth and in 16 month age heifers went over animals of the control group by 10%, that allowed their earlier use for reproduction. So, the results of conducted research showed, that twice a day injection of tissue drug "bio-tec" to dry cows in 10ml dose 60-55 and 40-35 days to calving contributes reducing of obstetric pathology. Subsequent use to calves in 4ml dose in 5-8 days age increases the safety of calves and positively influences the live weight gain, that in fact gives abilities of more effective cattle breeding.


2016 ◽  
Vol 18 (3(71)) ◽  
pp. 75-78
Author(s):  
Zh. Rybachuk

In the articles resulted the uses of preparation given inrelation to expediency are with adsorbent properties of «Еcosorb 25» for pigs that are on fattening. Undertakenstudies it is well–proven that introduction in the complementof ration of the indicated adsorbent from a calculation 5 kg/1the ton of forage is predetermined by an increase in the serum of blood of content of immunoproteins. Content ofimmunoproteins is in the serum of blood of pigs, that it isexposed to research to application of adsorbent was differentand was in a wide range, a mean value was 15.9 ± 3.2 gs/l immune status of investigational population is different Accordingly. Consider that such wide range of data testifiesto different activity of functioning of the immune system andconditioned by the different antigen loading each ofinvestigationalanimals. In a 21 twenty–four hours, after thebeginning of application of adsorbent of «Еcosorb 25» content of immunoproteins in the serum of blood of pigs of anexperience group is considerably less in comparing to theanimals that in composition a ration got «Ecosorb 25». Forthese pigs (control group) content of immunoproteins was at the level of a 16.6 ± 1.27g/l, but substantially differed for every animal, that testifiedtheir immune status to different. For the pigs of an experiencegroup a difference is between the least and maximal index ofcontent of immunoproteins presented 17.8% that specified onalmost identical reactivity of the immune system (reduction ofreceipt of antigens, maybe and mycotoxins from agastrointestinal tract). Got the given is conditioned by thedisplay of adsorbent action of preparation that is entered to the ration of pigs of an experience group. Positive influence of «Ecosorb 25» on functioning of the immune system atintroduction to the ration of pigs that are on fattening, theresults of research of serum of blood testify through 2 missesafter the beginning of application. Reduction to content of immunoproteins is registered in theserum of blood of pigs of control group on 15.7% comparing to the previous index (21twenty–four hours) and 19.5% animals of an experience group. For certain (Р ≥ 0,99) contentof immunoproteins increased in the serum of blood of pigs ofan experience group 17 ± 0.25 gs/of to 14.0 ± 0.76 g/l that maybe it contingently the receipt of substances with animmunodepressive action (including and micotoxins) in the organism of animals of control group. Id est, at feeding to the pigs of preparation of «Ecosorb 25» with adsorbent properties during 2th months, stipulated reduction of receiptof toxins in blood, and accordingly and reduction offunctional activity immune. It provides rapid reactivity of the immune system andsynthesis of sufficient amount of antibodies at the hit ofmicroorganisms to the organism of pigs, that in compositiona ration got an adsorbent. As for the animals of control group registered reduction to content of immunoproteins in theserum of blood, it testifies to weakening of functional activityof the immune system. The difference of content ofimmunoproteins in the serum of blood of pigs testifies to the increase of providing of better immunological defence in the organism of animals of anexperience group and reduction of him in a control group. 


Author(s):  
Alexander Viktorovich Zhestkov ◽  
Olga Olegovna Pobezhimova

Particular attention is paid to atopic dermatitis (AD) as one of the earliest and most frequent clinical manifestations of allergy in children. AD is a multifactorial disease, the development of which is closely related to genetic defects in the immune response and adverse environmental influences. It was found that the action of these factors determines the rate of development of AD, especially in young children. One of these factors is a violation of the intestinal microbiota, which plays an essential role in the development of the child's immune system and has a protective effect in the formation of atopy. It has been shown that 80-95% of patients with AD have intestinal dysbiosis, while, along with a deficiency of lactobacilli and bifidobacteria, there is an excessive growth of Staphilococcus. The use of modern molecular genetics technologies made it possible to obtain a fairly complete understanding of the number, genetic heterogeneity and complexity of the bacterial components of the intestinal microbiota, while clinical studies have shown the importance of its interactions with the host organism in the formation of various forms of pathology. It has been established that the human intestinal microbiota is an evolutionary set of microorganisms that exists as a balanced microecological system in which the symbiotic microflora is in dynamic equilibrium, forms microbial associations that occupy a certain ecological niche in it, and is one of the most important factors affecting human health. The gut microbiota plays an important role in the pathogenesis of atopic dermatitis, which causes immunosuppression, but the exact mechanism of its action is still unclear. It is widely known that probiotics act on the immune system. These are living microorganisms with immunomodulatory effects that stimulate Th1 cytokines and suppress Th2 responses, which are being investigated for the treatment of several diseases. The most commonly used probiotics are part of the intestinal microflora such as lactobacilli, bifidobacteria and enterococci. The purpose of this article: to systematize the information available today on the influence of the composition of the intestinal microflora on the immunopathogenesis of atopic dermatitis.


2020 ◽  
Vol 18 (3) ◽  
pp. e0612
Author(s):  
Mihaela Saracila ◽  
Tatiana D. Panaite ◽  
Cristina Tabuc ◽  
Cristina Soica ◽  
Arabela Untea ◽  
...  

This study aimed to determine the effect of dietary creeping wood sorrel powder (Oxalis corniculata) and chromium supplemented to broilers (1-42 days) exposed to heat stress, on their performance and on the intestinal and caecal microbiota.Area of study: Ilfov, RomaniaMaterial and methods: The feeding trial was conducted on 60, day-old Cobb 500 broilers, divided equally in two groups, each group with six replicates (5 chicks/ replicate). The broilers were housed in an experimental hall at 32° C constant temperature and 23h light regimen. Unlike the dietary control diet (C), the experimental diet (E) was supplemented with 1% creeping wood sorrel powder and 20 mg chromium picolinate/ kg premix. One bird from each replication was slaughtered on days 28 and 42, and samples of caecal and intestinal content were collected for bacteriological analysis.Main results: The dietary creeping wood sorrel powder and chromium supplements for heat-stressed broilers had no significant influence on their growth performance (1-42 d). Overall, E diet had a beneficial effect on the balance of the caecal microflora; however, in the intestine, E diet had a positive influence on the balance of the intestinal microflora, only for the samples collected at 28 days.Research highlights: Dietary creeping wood sorrel powder and chromium supplements can be an efficient tool for maintaining a proper balance of intestinal microflora in heat-stressed broilers. 


2003 ◽  
Vol 24 (1) ◽  
pp. 11 ◽  
Author(s):  
Harsharn Gill

The human gastrointestinal tract (GIT) harbours an extremely complex and diverse microbial ecosystem representing over 500 different species. While a majority of indigenous bacteria are benign or beneficial, some possess the potential to cause disease; in healthy individuals, a balance exists between these populations. In addition to nutritional and barrier functions, the intestinal microflora plays an important role in guiding the development of a balanced immune system and maintaining gut homeostasis. Perturbations in the microbial homeostasis due to factors such as antibiotic therapy, stress and infection enhances predisposition to increased risk of infectious diseases, cancers and immunoinflammatory disorders.


2021 ◽  
Vol 27 ◽  
pp. 87-89
Author(s):  
J. K. JOSEPH ◽  
B. AWOSANYA ◽  
P. C. ADEOYE ◽  
M. ROKEKUNLE

The effect of feeding graded levels of toasted banban ground out meal on rabbit weaners was investigated. A total of fifty white rabbit weaners of 6 - 8 weeks with an average weight of 366,7 gwere fed the graded level of tested bambara nut meal at 0. 5, 15, 25 or 35% inclusion level in a complete randomized design experiment for a period of six week. The final live weight, daily feed intake were not influcticed (P>0.05) by the level of bambara nut meal in the diet. However, positive influence of the graded level of bambara nut meal was observed on the rabbit daily weight gain, feed efficiency dressed carcass, dressing percentage and ment: bone ratjo. Rabbits on the 25 and 15% bambara nut inclusion levels were found to have similar (P>0.05) daily weight gain and dressing percentage with the control ration. Rabbit on the 5% bambara nut level diet had the least feed efficiency (0.22) and meat: bone ratio (3.6), while the dressed weights of rabbit fed the diet containing 25% bambara nut meal had the highest dressed carcass weight (501.6g). Rabbits' carcass cut-up parts as well as internal organs (liver, heart, kidneys and lungs) were not influenced by the dietary levels of bambara nut meal. But the pelt weight, empty gut weight, lipid and moisture contents were significantly (P<0.05) influenced by the levels of bambara nut meal in the diet. 


2021 ◽  
Vol 43 (1) ◽  
pp. 385-398
Author(s):  
S. I. Ajibola ◽  
S. O. Obasa ◽  
A. K. Akintokun ◽  
I. Abdulraheem

Immuno-nutrition studies have shown that some nutrients are linked to the immunological status of fish. Growth performance, nutrient utilization and intestinal microflora were examined in Clarias gariepinus. The 120 C. gariepimus fingerlings (weight, 2.33±0.07g)were fed Aloe barbadensis leaves-paste supplemented diets in 40L freshwater-filled plastic tanks ad libitum twice daily for 12 weeks. The experimental diets containing 40% crude protein were supplemented with three concentration of A. barbadensis leaves-paste: ABL1-1%; ABL2-2%; ABL3-3% and control-0%. Mean weight gain (MWG) and percentage weight gain (PWG) increased (p<0.05) as the concentration of A. barbadensis increased. MWG (17.95±0.78) and PWG (772.2±54.94) were highest in fish fed ABL3 and lowest MWG (11.92±1.16) and PWG (17.95±0.78) in fish fed control diet. Nutrients were better utilized among the diets supplemented group at different significant levels (p < 0.05). The highest value of ANPU was observed in ABL1 when compared to all other treatments including the control. Survival rate decreased as concentration of paste increased. There were no significant differences (p>0.05) in the total bacterial counts (TBC) in A. barbadensis leaves-paste supplemented diets and the control having the highest TBC (23.67 ±0.88 x 105 CFU/ml). Growth of total fungal counts (TFC) was not observed in ABLI. There was a reduction in TFC as the concentration increased in the other supplemented diets, and the control having the highest TFC (7.67 ± 0.44 x 105CFU/ml). The study concluded that inclusion of 1% A. barbadensis leaves-paste as supplement in the diet could effectively improve the growth performance, nutrient utilization and survival of cultured C. gariepinus. A. barbadensis leaves-paste could also reduce the microbial load of the fish.


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