scholarly journals BASES FOR METHODOLOGICAL APPROACHES TO FORECASTING OF PATHOGENESIS PROCESSES IN THE TREMATODE BODY AFTER ANIMAL CHEMOTHERAPY

2020 ◽  
pp. 57-62
Author(s):  
Bibik ◽  
Nacheva ◽  
Grebenshchikov ◽  
Nesterok ◽  
Dodonov
Keyword(s):  
Chemical Structure ◽  
Drug Action ◽  
Cellular Level ◽  
Egg Formation ◽  
Different Types ◽  
Morphometric Methods ◽  
Ovicidal Effect ◽  
Methodological Approaches ◽  
The One

The prospect of effective deworming is associated with the study of the mechanism of action of anthelmintics on helminths, its organs and tissues. The long-term use of methodological approaches using histological, histochemical and morphometric methods for studying organs and tissues of different types of trematodes (fascioli, euritrem, opisthorchia, dicrocelia, paramphistoma, etc.) after the anthelmintics action is effective, since it allows you to establish the mechanism and drug action on helminths. Using these methods, morphophysiological shifts were identified in the organs and tissues of trematodes, the degree of which corresponded proportionally to the dose of the applied anthelmintic on the one hand, and was determined by the chemical structure of the drug itself and the duration of its exposure, on the other. The importance of the trematodocidal effect of anthelmintics is associated with the ovicidal effect and the blocking of the trematode reproduction in which the process of egg formation is disturbed. The egg pathology covers not only the destruction of the structure of their contents at the cellular level, but is also associated with the destruction of their genome. The cessation of the release of invasive material or the release of degenerative eggs into the environment after deworming contributes to the ecologic sterilization of the environment, and its sanitation.

scholarly journals Flat Glass or Crystal Dome Aperture? A Year-Long Comparative Analysis of the Performance of Light Pipes in Real Residential Settings and Climatic Conditions

2020 ◽  
Vol 12 (9) ◽  
pp. 3858 ◽  
Author(s):  
Magda Sibley ◽  
Antonio Peña-García
Keyword(s):  
Comparative Analysis ◽  
Flat Glass ◽  
Climatic Conditions ◽  
Long Term Effect ◽  
Different Types ◽  
The Difference ◽  
The Aesthetic ◽  
One Year ◽  
The One

This paper presents the first comparative study of its type of the performance of light pipes with different types of apertures: a flat glass versus a bohemian crystal dome. Measurements were taken at 20-minute intervals over a period of one year in the bathrooms of two newly built identical houses of the same orientation located in Manchester, UK. The comparative analysis of the data collected for both light pipes types reveals that the crystal domed aperture consistently outperforms the flat glass one. Furthermore, the difference in the recorded horizontal illuminance is most marked during the winter months and at the end of the one-year experiment, indicating that the crystal dome has better performance for low incident winter light and higher resistance for the long term effect of weathering and pollution. This study provides strong evidence based on long term real measurements. Such evidence informs architects’ decisions when weighing up the aesthetic considerations of a flat glass aperture versus the higher illumination levels afforded by a crystal dome aperture with higher resistance to weathering and pollution.

Nostalgic neighborhood belongings: Theorizing the interrelationship among nostalgias, belongings and neighborhood changes

2021 ◽  
pp. 003802612110294
Author(s):  
Clément Colin
Keyword(s):  
Empirical Research ◽  
The Other ◽  
The Past ◽  
Physical Environments ◽  
The Social ◽  
Different Types ◽  
The One ◽  
Depth Interviews

Depending on one’s socio-territorial contexts, age, and time spent residing in the same place, the spatial-temporal experience of belonging is lived differently. Within this framework, this article looks at perspectives of neighborhood belonging in long-term residents aged 65 years and older. Based on the narratives of 51 people from three neighborhoods of Valparaíso, Chile, who participated in the 2019 workshops and/or in-depth interviews, I identify different types of nostalgic senses of belonging; and examine the social and spatial conditions that influence their formation. From this empirical research, I argue that these belongings are based on daily practices that refer to the past neighborhood and that, at the same time, are embodied in their current materialities. The results show, on the one hand, the role of nostalgia in the formation of a belonging, from the past to the present; and, on the other, the influence of place in these experiences. From the above, this article contributes to the conceptualization of the material dimension of nostalgic belongings and their interrelationships among nostalgias, belongings, and changes in social and physical environments.

scholarly journals Bartók and the Violin Music of Maramureș

2021 ◽  
Vol 62 (1-2) ◽  
pp. 85-103
Keyword(s):  
Primary Sources ◽  
Dance Music ◽  
Primitive Character ◽  
Violin Concerto ◽  
Violin Music ◽  
Different Types ◽  
Original Works ◽  
The One ◽  
Evolutionary Progression

Abstract The Second Rhapsody, one of Bartók’s technically most demanding concert pieces for violin, arranges archaic-improvisatory bagpipe imitations for concert performance. The arrangement itself shows a well-designed, coherent structure: the succession of dances, tonally and motivically related between each other, outline a kind of evolutionary progression from free motive-structure to strophic form. Bagpipe-music had a long-term influence on Bartók’s violin music, figuring as episodes in original works like the two Violin Sonatas or the Violin Concerto; but none exploits the genre to such an extent as the Second Rhapsody. The violin pieces with motive-structure of fascinatingly wild and virtuoso character were among Bartók’s major discoveries of the collecting trips to the Maramureş region. For the Rhapsody Bartók chose melodies from the one-time Ugocsa county, whose music, closely related to that of Maramureş county, was considered by him “the most interesting in our country [i.e., Hungary of the time], due exactly to its primitive character.” In Maramureş these melodies are less eccentric; instead, the violinists have a broader and more varied repertoire of dance music. In my article I discuss the different types of violin music of this region, focusing on structural, melodic, or interpretational elements that were of special interest for the composer. For this investigation I have made use of the primary sources of the respective collections: phonogram recordings, field notations, later transcriptions.

Planning Implications of Golf Tourism

2006 ◽  
Vol 6 (3) ◽  
pp. 170-178 ◽  
Author(s):  
Gerda K. Priestley
Keyword(s):  
Local Community ◽  
Course Development ◽  
Golf Courses ◽  
Property Development ◽  
Advantages And Disadvantages ◽  
Tourism Product ◽  
Tourism Sector ◽  
Different Types ◽  
The One

The development of golf tourism requires the provision not only of one or more golf courses, but also of many other related infrastructures and facilities, obviously including hotels and other forms of property development. As a result, the process of the development of golf as a tourism product generates a profound impact on the location in which it takes place and can provoke conflicts and even imbalances where it is implanted. It is therefore essential to plan golf tourism regions carefully in order to make economic and social objectives compatible and thus contribute to the sustainability of the tourism sector, the product, the territory, the landscape and the local community. The issues examined in this paper include: the advisability of specific legislation for the implantation of golf, and of urban planning; the search for a correct balance between residential and hotel development on the one hand and golf course development on the other; the relative advantages and disadvantages of different types of property development, and its location both on and away from the coast; and the integration of golf courses in the landscape. Golf tourism development faces various challenges in its efforts to comply with the widespread objectives of overall sustainability, which include: economic profitability; long-term viability as a product; environmental integration and improvement; and cultural acceptability. This contribution aims to outline some steps to the achievement of these objectives. Firstly, the structure of golf tourism (from the perspective of its implications for planning) is briefly outlined to set the scene, including an evaluation of the different types of construction that are associated. The concept, objectives and process of tourism planning are outlined, followed by reference to aspects that are particularly applicable to the case of golf tourism. The problem facing planners is then defined. The instruments available and the initiatives and solutions most frequently applied in planning for golf tourism are examined and, finally, some recommendations are offered.

Unlearning institutional habits: an arts-based perspective on organizational unlearning

2019 ◽  
Vol 26 (5) ◽  
pp. 485-499
Author(s):  
Annette Krauss
Keyword(s):  
Alternative Education ◽  
Content Type ◽  
Institutional Structures ◽  
The Commons ◽  
Project Site ◽  
Areas Of Concern ◽  
Methodological Approaches ◽  
New Perspective ◽  
The One

Purpose This paper aims to report on findings and methodological approaches of the artistic project “Sites for Unlearning (Art Organization)” in collaboration with the Team at Casco at Institute: Working for the Commons, Utrecht/NL, through which processes of unlearning are tested against the backdrop of established institutional structures. This paper constitutes a transdisciplinary contribution to the discourse, exploring its relationship with organizational unlearning, organizational change and feminist, decolonial trajectories. Design/methodology/approach This paper proposes a feminist, decolonial, arts-based approach to discuss “unlearning institutional habits” by means of the long-term project – Sites for Unlearning (Art Organization). This complements the organizational unlearning literature with an arts-based approach, which draws on alternative education and feminist and decolonial literature. This paper responds to the call of this special and introduces a new perspective to the discourse. Findings This paper gives insights into and elaborates on the findings of the artistic project “Site for Unlearning (Art Organization)” through which processes of unlearning are tested against the backdrop of institutional structures. Originality/value This methodology puts in evidence that there are two major areas of concern for those who desire to break established structures in contemporary life increasingly defined by economic, socio-political and ecological pressures – institution on the one hand and learning on the other; the artistic project Sites for Unlearning attempts to challenge both. It builds on the insights and energies developed in and around the studies on unlearning in the fields of alternative education and feminist and decolonial theory and connects them with organizational learning, knowledge management and theories of transformation (Andreotti, 2011; Spivak, 1993; Tlostanova and Mignolo, 2012).

Potential Uses of Vinegar as a Medicine and Related in vivo Mechanisms

2016 ◽  
Vol 86 (3-4) ◽  
pp. 127-151 ◽  
Author(s):  
Zeshan Ali ◽  
Zhenbin Wang ◽  
Rai Muhammad Amir ◽  
Shoaib Younas ◽  
Asif Wali ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Review Paper ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Active Role ◽  
Current Review ◽  
Different Types ◽  
Positive Effect

While the use of vinegar to fi ght against infections and other crucial conditions dates back to Hippocrates, recent research has found that vinegar consumption has a positive effect on biomarkers for diabetes, cancer, and heart diseases. Different types of vinegar have been used in the world during different time periods. Vinegar is produced by a fermentation process. Foods with a high content of carbohydrates are a good source of vinegar. Review of the results of different studies performed on vinegar components reveals that the daily use of these components has a healthy impact on the physiological and chemical structure of the human body. During the era of Hippocrates, people used vinegar as a medicine to treat wounds, which means that vinegar is one of the ancient foods used as folk medicine. The purpose of the current review paper is to provide a detailed summary of the outcome of previous studies emphasizing the role of vinegar in treatment of different diseases both in acute and chronic conditions, its in vivo mechanism and the active role of different bacteria.

Intraindividual Variability and Stability of Affect and Well-Being

GeroPsych ◽  
2013 ◽  
Vol 26 (3) ◽  
pp. 185-199 ◽  
Author(s):  
Christina Röcke ◽  
Annette Brose
Keyword(s):  
Age Differences ◽  
Well Being ◽  
Subjective Well Being ◽  
Emotional Experiences ◽  
Short Term ◽  
Regulatory Processes ◽  
Functional Implications ◽  
Methodological Approaches ◽  
Underlying Processes

Whereas subjective well-being remains relatively stable across adulthood, emotional experiences show remarkable short-term variability, with younger and older adults differing in both amount and correlates. Repeatedly assessed affect data captures both the dynamics and stability as well as stabilization that may indicate emotion-regulatory processes. The article reviews (1) research approaches to intraindividual affect variability, (2) functional implications of affect variability, and (3) age differences in affect variability. Based on this review, we discuss how the broader literature on emotional aging can be better integrated with theories and concepts of intraindividual affect variability by using appropriate methodological approaches. Finally, we show how a better understanding of affect variability and its underlying processes could contribute to the long-term stabilization of well-being in old age.

The Acute Effect of Alcohol on Various Memory Processes

2010 ◽  
Vol 24 (4) ◽  
pp. 249-252 ◽  
Author(s):  
Márk Molnár ◽  
Roland Boha ◽  
Balázs Czigler ◽  
Zsófia Anna Gaál
Keyword(s):  
Low Dose ◽  
Short Term Memory ◽  
Acute Effect ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Processes ◽  
Different Types ◽  
The Brain ◽  
Legal Consequences

This review surveys relevant and recent data of the pertinent literature regarding the acute effect of alcohol on various kinds of memory processes with special emphasis on working memory. The characteristics of different types of long-term memory (LTM) and short-term memory (STM) processes are summarized with an attempt to relate these to various structures in the brain. LTM is typically impaired by chronic alcohol intake but according to some data a single dose of ethanol may have long lasting effects if administered at a critically important age. The most commonly seen deleterious acute effect of alcohol to STM appears following large doses of ethanol in conditions of “binge drinking” causing the “blackout” phenomenon. However, with the application of various techniques and well-structured behavioral paradigms it is possible to detect, albeit occasionally, subtle changes of cognitive processes even as a result of a low dose of alcohol. These data may be important for the consideration of legal consequences of low-dose ethanol intake in conditions such as driving, etc.

Radioimmunotherapy for treatment of acute myeloid leukaemia and myelodysplastic syndrome

2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Primary Tumour ◽  
The Other ◽  
Haematopoietic Stem Cell ◽  
Other Hand ◽  
Primary Reduction ◽  
The One ◽  
Acute Myeloid

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.

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