scholarly journals Estimation of the SARS-CoV-2 specific reproduction number in SAARC countries: A 60-days Data-driven analysis

2020 ◽  
Vol 12 (4) ◽  
pp. 628-634
Author(s):  
Mohammed Nizam Uddin ◽  
A.N.M. Rezaul Karim ◽  
Sofi Mahmud Parvez ◽  
RiazMahmud ◽  
H. M. Shahadat Ali ◽  
...  

Novel coronavirus disease-2019 (COVID-19) was acknowledged as a global pandemic by WHO, which was first observed at the end of December 2019 in Wuhan city, China, caused by extreme acute respiratory syndrome coronavirus2 (SARS-CoV-2). According to the Weekly operation Update on COVID-19 (November 13, 2020) of the World Health Organization, more than 53 million confirmed cases are reported, including 1.3 million deaths. Various precautionary measures have been taken worldwide to reduce its transmission, and extensive researches are going on. The purpose of this analysis was to determine the initial number of reproductions (Ro) of the coronavirus of SAARC countries named Afghanistan, Bangladesh, India, Pakistan, Bhutan, Nepal, the Maldives, and Sri-Lanka for the first 60 days as the growth is exponential in the early 60 days. The reproduction numbers of coronavirus for Afghanistan, Bangladesh, India, Pakistan, Bhutan, the Maldives, Nepal, and Sri Lanka are 1.47, 3.86, 2.07, 1.43, 1.31, 3.22, 1.75, and 2.39 respectively. The basic reproduction number (R0) 3.86 for Bangladesh and 1.31 for Bhutan indicated that up to 60-days of the outbreak COVID-19, the epidemic was more severe in Bangladesh and less severe in Bhutan among all the SAARC countries. Our predictions can be helpful in planning alertness and taking the appropriate measures to monitor it.

Author(s):  
Samson Chama ◽  
◽  
Enouce Ndeche ◽  

The first cases of COVID-19 pneumonia were identified in Wuhan City, China, in December 2019. In January 2020, a novel coronavirus, known as SARS-CoV-2, was identified as the cause of this outbreak. The virus, and the human disease it causes, have evolved into a global pandemic. As of April 29, 2020, according to the World Health Organization, cases have been confirmed in 213 countries, areas, or territories, with 3,090,445 confirmed cases so far, and 217,769 confirmed deaths [1].


Author(s):  
Mostafa Al-Emran

A novel coronavirus (COVID-19) has been identified in Wuhan, China, in late 2019 (Zhu et al., 2020). On March 11, 2020, the World Health Organization (WHO) has declared the outbreak of COVID-19 as a global pandemic (Cucinotta & Vanelli, 2020). In responding to this pandemic, a series of precautionary measures have been taken forward on a global basis to combat the spread of the virus. One of such measures was the lockdown of educational institutions. To compromise between the delivery of learning to students and committing to social distancing, the transition to distance learning was the unavoidable option in such crises.


Author(s):  
Lara Bittmann

On December 31, 2019, WHO was informed of cases of pneumonia of unknown cause in Wuhan City, China. A novel coronavirus was identified as the cause by Chinese authorities on January 7, 2020 and was provisionally named "2019-nCoV". This new Coronavirus causes a clinical picture which has received now the name COVID-19. The virus has spread subsequently worldwide and was explained on the 11th of March, 2020 by the World Health Organization to the pandemic.


Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1145
Author(s):  
Hakimeh Baghaei Daemi ◽  
Muhammad Fakhar-e-Alam Kulyar ◽  
Xinlin He ◽  
Chengfei Li ◽  
Morteza Karimpour ◽  
...  

Influenza is a highly known contagious viral infection that has been responsible for the death of many people in history with pandemics. These pandemics have been occurring every 10 to 30 years in the last century. The most recent global pandemic prior to COVID-19 was the 2009 influenza A (H1N1) pandemic. A decade ago, the H1N1 virus caused 12,500 deaths in just 19 months globally. Now, again, the world has been challenged with another pandemic. Since December 2019, the first case of a novel coronavirus (COVID-19) infection was detected in Wuhan. This infection has risen rapidly throughout the world; even the World Health Organization (WHO) announced COVID-19 as a worldwide emergency to ensure human health and public safety. This review article aims to discuss important issues relating to COVID-19, including clinical, epidemiological, and pathological features of COVID-19 and recent progress in diagnosis and treatment approaches for the COVID-19 infection. We also highlight key similarities and differences between COVID-19 and influenza A to ensure the theoretical and practical details of COVID-19.


2020 ◽  
Vol 30 (1) ◽  
pp. 38030 ◽  
Author(s):  
Deivendran Kalirathinam ◽  
Raj Guruchandran ◽  
Prabhakar Subramani

The 2019 novel coronavirus officially named as coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization, has spread to more than 180 countries. The ongoing global pandemic of severe acute respiratory syndrome coronavirus, which causes COVID-19, spread to the United Kingdom (UK) in January 2020. Transmission within the UK was confirmed in February, leading to an epidemic with a rapid increase in cases in March. As on April 25- 2020, there have been 148,377 confirmed cases of COVID-19 in the UK and 20,319 people with confirmed infection have died. Survival of critically ill patients is frequently associated with significant functional impairment and reduced health-related quality of life. Early physiotherapy and community rehabilitation of COVID-19 patients has recently been identified as an essential therapeutic tool and has become a crucial evidence-based component in the management of these patients. This comprehensive narrative review aims to describe recent progress in the application of physiotherapy management in COVID 19 patients. Assessment and evidence- based treatment of these patients should include prevention, reduction of adverse consequences in immobilization, and long-term impairment sequelae. A variety of techniques and modalities of early physiotherapy in intensive care unit are suggested by clinical research. They should be applied according to the stage of the disease, comorbidities, and patient’s level of cooperation.


Author(s):  
Jeremy Smelt ◽  
Gowthanan Santhirakumaran ◽  
Paul Vaughan ◽  
Ian Hunt ◽  
Carol Tan

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus primarily affecting the respiratory system, was initially diagnosed in Wuhan, China, in late 2019. Identified as coronavirus disease 2019 (COVID-19) by the World Health Organization, the virus rapidly became a global pandemic. The effects on health care worldwide were unprecedented as countries adapted services to treat masses of critically ill patients.The aim of this study is to analyze the effect that the COVID-19 pandemic had on thoracic surgery at a major trauma center during peak prevalence. Methods Prospective unit data were collected for all patients who underwent thoracic surgery during March 2020 until May 2020 inclusive. Retrospective data were collected from an earlier comparable time period as a comparison. Results In the aforementioned time frame, 117 thoracic surgical operations were performed under the care of four thoracic surgeons. Six operations were performed on three patients who were being treated for SARS-CoV-2. One operation was performed on a patient who had recovered from SARS-CoV-2. There were no deaths due to SARS-CoV-2 in any patient undergoing thoracic surgery. Conclusion This study demonstrates that during the first surge of SARS-CoV-2, it was possible to adapt a thoracic oncology and trauma service without increase in mortality due to COVID-19. This was only possible due to a significant reduction in trauma referrals, cessation of benign and elective work, and the more stringent reprioritization of cancer surgery. This information is vital to learn from our experience and prepare for the predicted second surge and any similar future pandemics we might face.


2021 ◽  
Vol 58 (3) ◽  
pp. 3444-3456
Author(s):  
Mr J Dorasamy, Et. al.

The World Health Organization (Who) In March 2020 Declared Covid 19 A Pandemic, Due To The  Global And Rapid Spread Of A Novel Coronavirus (Who, 2020). The Covid 19 Pandemic Being Highly Infectious And Unpredictable, Has  Disrupted  Social, Economic, Environmental And Political Spheres Of Life. Globally, People Have Ventured Into A “Lockdown World”, Increasing Uncertainty About Their Future Amidst The Covid 19 Pandemic. As A Result Of The Pandemic, Social Alteration Has Taken The Form Of Social Distancing, Self-Isolation And Self-Quarantine.  Many Were Unprepared For The Shift From The “Normal”, Propelling  Undue  Stress Under The New Normal Way Of Doing Things During The Current Global Pandemic Crisis. This Has Been Accompanied By Social, Emotional And Mental Effects, As The Ongoing And Fluid Nature Of The Pandemic Has Created Uncertainty For Many People. The Covid 19 Pandemic, As A Multidimensional Stressor Affecting Wellbeing, Has Affected Individuals, Families, Educational, Occupational, And Broader Societal Systems.  


Author(s):  
Oyelola A. Adegboye ◽  
Adeshina I. Adekunle ◽  
Ezra Gayawan

On 31 December 2019, the World Health Organization (WHO) was notified of a novel coronavirus disease in China that was later named COVID-19. On 11 March 2020, the outbreak of COVID-19 was declared a pandemic. The first instance of the virus in Nigeria was documented on 27 February 2020. This study provides a preliminary epidemiological analysis of the first 45 days of COVID-19 outbreak in Nigeria. We estimated the early transmissibility via time-varying reproduction number based on the Bayesian method that incorporates uncertainty in the distribution of serial interval (time interval between symptoms onset in an infected individual and the infector), and adjusted for disease importation. By 11 April 2020, 318 confirmed cases and 10 deaths from COVID-19 have occurred in Nigeria. At day 45, the exponential growth rate was 0.07 (95% confidence interval (CI): 0.05–0.10) with a doubling time of 9.84 days (95% CI: 7.28–15.18). Separately for imported cases (travel-related) and local cases, the doubling time was 12.88 days and 2.86 days, respectively. Furthermore, we estimated the reproduction number for each day of the outbreak using a three-weekly window while adjusting for imported cases. The estimated reproduction number was 4.98 (95% CrI: 2.65–8.41) at day 22 (19 March 2020), peaking at 5.61 (95% credible interval (CrI): 3.83–7.88) at day 25 (22 March 2020). The median reproduction number over the study period was 2.71 and the latest value on 11 April 2020, was 1.42 (95% CrI: 1.26–1.58). These 45-day estimates suggested that cases of COVID-19 in Nigeria have been remarkably lower than expected and the preparedness to detect needs to be shifted to stop local transmission.


2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Emanuele Nicastri ◽  
Nicola Petrosillo ◽  
Tommaso Ascoli Bartoli ◽  
Luciana Lepore ◽  
Annalisa Mondi ◽  
...  

On January 9th, 2020, the “World Health Organization” (WHO) declared the identification, by Chinese Health authorities, of a novel coronavirus, further classified as SARS-CoV-2 responsible of a diseases (COVID-19) ranging from asymptomatic cases to severe respiratory involvement. On March 9th, 2020, WHO declared COVID-19 a global pandemic. Italy is the second most affected country by COVID-19 infection after China. The “L. Spallanzani” National Institute for the Infectious Diseases, IRCCS has been the first Italian hospital to admit and manage patients affected by COVID-19. Hereby, we show our recommendations for the management of COVID-19 patients, based on very limited clinical evidences; these recomendations should be considered as expert opinions, which may be modified according to newly produced literature data. *for the INMI COVID-19 Treatment Group – ICOTREG Abdeddaim A, Agrati C, Albarello F, Antinori A, Ascoli Bartoli T, Baldini F, Bellagamba R, Bevilacqua N, Bibas M, Biava G, Boumis E, Busso D, Camici M, Capobianchi MR, Capone A, Caravella I, Cataldo A, Cerilli S, Chinello G, Cicalini S, Corpolongo A, Cristofaro M, D’Abramo A, Dantimi C, De Angelis G, De Palo MG, D’Offizi G, De Zottis F, Di Lorenzo R, Di Stefano F, Fusetti M, Galati V, Gagliardini R, Garotto G, Gebremeskel Tekle Saba, Giancola ML, Giansante F, Girardi E, Goletti D, Granata G, Greci MC, Grilli E, Grisetti S, Gualano G, Iacomi F, Iannicelli G, Ippolito G, Lepore L, Libertone R, Lionetti R, Liuzzi G, Loiacono L, Macchione M,  Marchioni L, Mariano A, Marini MC, Maritti M, Mastrobattista A, Mazzotta V, Mencarini P, Migliorisi-Ramazzini P, Mondi A, Montalbano M, Mosti S, Murachelli S, Musso M, Nicastri E, Noto P, Oliva A, Palazzolo C, Palmieri F, Pareo C, Petrone A, Pianura E, Pinnetti C, Pontarelli A, Puro V, Rianda A, Rosati S, Sampaolesi A, Santagata C, Scarcia D’Aprano S, Scarabello A, Schininà V, Scorzolini L, Stazi GV, Taibi C, Taglietti F, Tonnarini R, Topino S, Vergori A, Vincenzi L, Visco-Comandini U, Vittozzi P, Zaccarelli M, Zaccaro G.


2021 ◽  
Vol 9 (2) ◽  
pp. 60-69
Author(s):  
Ridwan Olamilekan Adesola ◽  
Oluwatobi Emmanuel Oladele ◽  
Ahmed Oluwasegun Tajudeen ◽  
Ogundepo Oluwatobi Moses ◽  
Murali Dinesh

Coronavirus disease 2019 (COVID-19), confirmed as the global pandemic on March 11, 2020, by the World Health Organization (WHO), was caused by the outbreak of an emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was first reported in Wuhan city, China, in December 2019. Based on the previous pandemic, such as severe acute respiratory syndrome (SARS) from 2002 to 2003, Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012. The scientific developments have fast-tracked our insights SARS-CoV-2 epidemiology, likewise vaccinology relevant for developing drugs for viral infections treatment. As there are not many detailed interventions and vaccines available for disease control, the pandemic COVID-19 poses countless threats to global public health, causing a great level of insecurity and unrest worldwide. To provide an inclusive overview to global health authorities and prospective readers worldwide, we detailed in this review the epidemiology and vaccinology of SARS-CoV-2 in Nigeria.


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