scholarly journals Antimicrobial activity in leaf, seed extract and seed oil of Jatropha curcas L. plant

2011 ◽  
Vol 3 (1) ◽  
pp. 102-105 ◽  
Author(s):  
Sanjay Mohan Gupta ◽  
Mohommad Arif ◽  
Zakwan Ahmed
Keyword(s):  
Jatropha Curcas ◽  
Leaf Extract ◽  
Seed Oil ◽  
Seed Extract ◽  
Food Preservation ◽  
Natural Food ◽  
Moderate Activity ◽  
Significant Activity ◽  
Medicinal Uses ◽  
Antibacterial And Antifungal

The study on antibacterial and antifungal efficacy of leaf and seed extract and seed oil of Jatropha curcas reveals that the inhibition zones ranged from 7 to 22 mm for antibacterial and from 10 to 20 mm for antifungal activity. Among all extracts tested, seed extract showed significant activity while leaf extract showed intermediate activity against gram-positive bacteria. In case of gram-negative bacteria, seed extract and seed oil has shown some moderate activity whereas, no activity was observed in leaf extract. In case of fungal cultures, among all test extracts only seed extract showed significant activity against Mucor and Tilletia fungus, while in case of Rhizopus no activity was observed against all test extracts. These results indicated the possibility of using Jatropha extract and seed oil for medicinal uses and natural food preservation.

scholarly journals Final Report on the Safety Assessment of Corylus Avellana (Hazel) Seed Oil, Corylus Americana (Hazel) Seed Oil, Corylus Avellana (Hazel) Seed Extract, Corylus Americana (Hazel) Seed Extract, Corylus Rostrata (Hazel) Seed Extract, Corylus Avellana (Hazel) Leaf Extract, Corylus Americana (Hazel) Leaf Extract, and Corylus Rostrata (Hazel) Leaf Extract

2001 ◽  
Vol 20 (1_suppl) ◽  
pp. 15-20 ◽  
Keyword(s):  
Leaf Extract ◽  
Seed Oil ◽  
Corylus Avellana ◽  
Seed Extract ◽  
Species Tree ◽  
Radiation Absorption ◽  
Final Report ◽  
Seed Oils ◽  
Limited Information ◽  
Method Of Extraction

These ingredients are all derived from hazelnut trees. The two seed oils are expressed from the nuts of the hazelnut tree of the particular species identified. Most current reported cosmetic uses are of the seed oils. The seed extracts are the extract of the nuts of the identified species tree. There is one current report of use of seed extract in cosmetics. The leaf extracts are the extract from the leaves of the particular species tree. There are no current reports of use of these extracts in cosmetics. Analysis of seed oil from one species identified Oleic Acid, Palmitoleic Acid, Linoleic Acid, Eicosaenoic Acid, Docosenoic Acid, Eicosanoic Acid, Palmitic Acid, Linolenic Acid, Stearic Acid, and Tetraeicosanoic Acid. Little information is available to characterize the extracts, however. The functions of most of these ingredients in cosmetics are not reported. In studies of hazelnuts from Spain and Egypt, aflatoxin was reported as a possible contaminant. Aflatoxins are considered carcinogenic in humans. Virtually no safety test data are available on these ingredients. Negative results in one comedogenicity study using a seed oil are reported. Cross-sensitivity to proteins in peanuts and those in hazelnuts are reported, but the presence or absence of protein in nut extract and plant extract from hazelnut trees is not known. Additional data were provided regarding concentration of use, method of extraction and contaminants, comedogenicity, and ultraviolet (UV) radiation absorption, but these data related to nut oil from only one species, and were not overall sufficient to resolve questions about irritation, sensitization, and photosensitization. Because of the absence of data, it is concluded that the available data are insufficient to support the safety of these ingredients in cosmetic products. Because of the limited information that characterizes any of these oils or extracts, data are needed on each (except that items 1, 2, and 3 below are not needed for Hazel [Corylus Avellana] Nut Oil). The additonal data needs include: (1) current concentration of use; (2) method of extraction/manufacture and quality control (i.e., chemical analyses); (3) contaminants and methods of extraction (especially pesticides and heavy metals); (4) dermal irritation and sensitization; (5) UV absorption; if there is significant absorption, then a photosensitization study will be needed; (6) 28-day dermal toxicity; (7) reproductive and developmental toxicity; and (8) two genotoxicity assays, one in a mammalian system; if positive, then a 2-year dermal carcinogenesis study using National Toxicology Program (NTP) methods may be needed.

scholarly journals In-Vitro Evaluation of Antibacterial, Antifungal and Anti-HIV Effects of Calophyllum inophyllum Leaf Extract

2020 ◽  
Vol 13 (4) ◽  
pp. 2003-2014
Author(s):  
Arun Kumar ◽  
Yashika Garg
Keyword(s):  
Leaf Extract ◽  
Rapid Development ◽  
Human Pathogens ◽  
Bacterial Strains ◽  
Medicinal Uses ◽  
Development Of Resistance ◽  
Pure Compounds ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal

Background:Calophylluminophyllum is an evergreen tree with ethno-medical value growing along the seashores and islands of the Pacific and Indian Ocean. All parts of the plant such as bark, seeds and leaves have diverse medicinal uses such as an antiseptic, analgesic in wound healing, astringent, diuretic, purgative and expectorant. Although many species of calophyllum have been studied phytochemically for pharmacological properties, reports on inophyllum species are scanty. Aim of the study:Keeping inview it’s medical importance and availability in India as well as the rapid development of resistance by pathogens to the commonly used synthetic antibiotics,the pharmacological effects of C. inophyllum leaf extract (CIE) on HIV, bacteria and fungi causative of many human diseases was assessed in this study. Material and Methods: Isolation of the pure compounds from the ethanolic CIE was performed by gross column chromatography and tested against lyophilized forms of 8 fungal and 14 bacterial strains grown on Sabouraud’s dextrose agar and nutrient agar media respectively. Fractions and pure compounds isolated from CIE were evaluated against HIV by the HIV-RT inhibition assay by using the RT assay kit(Roche). The results were tabulated and analysed. Results: Among the purified compounds, Inophyllum C & E exhibited significant antibacterial and antifungal properties. Moreover, Inophyllum E was more potent than Inophyllum C in inhibiting the tested strains of bacteria and fungi whereasInophyllum B shows highest antiretroviral activity. Conclusion:We conclude that CIEis aneffective antimicrobial agent against common human pathogens tested in this in-vitro pharmacological evaluation of CIE.

Design, Synthesis and Antibacterial, Antifungal Activity of Some Coumarin Acetohydrazide Derivatives

2021 ◽  
pp. 3931-3937
Author(s):  
A. R. Chabukswar ◽  
P.V. Adsule ◽  
P.B. Randhave ◽  
Manini Mantri
Keyword(s):  
Antifungal Activity ◽  
Moderate Activity ◽  
Gram Negative Bacteria ◽  
Significant Activity ◽  
Design Synthesis ◽  
E Coli ◽  
Gram Positive Bacteria ◽  
Antibacterial And Antifungal ◽  
Gyrase Inhibitors

We have designed and synthesized (Z)-2-(5-methyl-2-oxo-2H-chromen-7-yl) oxy)-N’-(2-oxoindolin-3-ylidin) acetohydrazide derivatives by reacting 7-hydroxy-4-methyl-coumarin and substituted isatin to afford 12 substituted coumarin acetohydrazide derivatives. The synthesized compounds of coumarin acetohydrazide derivatives were designed and evaluated to study for their possible interactions as DNA gyrase inhibitors. All the synthesized coumarin acetohydrazide compounds have been characterized by spectral analysis IR, 1H NMR and mass spectroscopy. The compounds have been evaluated for In vitro antibacterial and antifungal activity against S. aureus, B. subtilus, E. coli, P. aeruginosa and fungi C. albicans and A. niger. In case of Gram positive bacteria and Gram negative bacteria Compound P5C, M5C, C5C exhibited significant activity. Compounds P5N, M5N, C5N shown moderate activity. Compound P5C, M5C, C5C shown significant Antifungal activity against C. albicans and A. niger. Compounds P5C, M5C, C5C are found to exert significant antibacterial as well as antifungal activity and can serve as potential compound against infectious diseases in future.

Synthesis, Characterization and Antimicrobial Evaluation of Some N-Substituted Benzimidazole Derivatives

2020 ◽  
Vol 17 (1) ◽  
pp. 87-91 ◽  
Author(s):  
Anuj Kumar ◽  
Yogesh Kumar ◽  
Jagdish K. Sahu ◽  
Sushil Kumar
Keyword(s):  
Antimicrobial Agents ◽  
New Technologies ◽  
Biological Properties ◽  
Benzimidazole Derivatives ◽  
Dilution Method ◽  
Moderate Activity ◽  
Significant Activity ◽  
Microbial Diseases ◽  
Serial Dilution Method ◽  
Antibacterial And Antifungal

Background: Due to the appearance of communicable microbial diseases and the toxicity related with presently used several antimicrobials such as β-lactam antibiotics, tetracyclines, quinolones, macrolides, glycopeptides (vancomycin) etc, demand for new antimicrobial agents has become a great concern in new technologies to improve efficacy and safety. Methods: In search of new antimicrobial agents with higher potency, some N-substituted benzimidazole derivatives (4, 5a-5h & 6) were obtained by chloroacetylation of benzimidazole followed by reaction with different amines, which were characterized by spectroscopic methods. All the target compounds were evaluated for their antibacterial and antifungal activity against microorganisms using two-fold serial dilution method. Results: Among the compounds evaluated, compounds 4 and 5d exhibited potent activity against Bacillus thuringiensis and Candida albicans while showed moderate activity against Escherischia coli when compared to amoxicillin and fluconazole. Compound 5a showed significant activity against tested microorganisms. Conclusion: From the current study, it may be concluded that synthesized compounds are fulfilling in terms of their structural distinctiveness and marked biological properties. These compounds might be encouraged to initiate a new class of antimicrobial agents.

scholarly journals Natural Food Preservation Based on Randu Leaf Extract (Ceiba pentadra) and White Onion (Allium sativum) Extract on The Intensity of Bacterial Series In Tomato and Bakso Beef

2020 ◽  
Vol 3 ◽  
pp. 437-439
Author(s):  
Muhammad Syarif Hidayat ◽  
Retno Sri Iswari ◽  
Siti Harnina Bintari
Keyword(s):  
Leaf Extract ◽  
Room Temperature ◽  
Allium Sativum ◽  
Food Preservation ◽  
Natural Food ◽  
Food Preservatives ◽  
Randomized Design ◽  
Garlic Bulb ◽  
Completely Randomized Design ◽  
Tuber Extract

The purpose of this study was to determine the effect of kapok leaf extract and garlic extract tubers effectively inhibit bacteria in tomatoes and beef meatballs. The research design uses a completely randomized design (CRD) which consists of one factor, namely food preservatives. Tomato and beef meatballs samples were immersed in kapok leaf extract and garlic bulb extract with different concentrations, namely 0, 50% and 50%, 100% garlic bulb extract and 100% kapok leaf extract for 15 minutes. Then the samples were stored at room temperature ranging from 22-31 degrees centigrade for 5 days. The results showed that the kapok leaf extract and garlic tuber extract effectively inhibited inhibiting bacteria.

Antibacterial, Antifungal and Antioxidant activity of leaf and fruit of Alangium salviifolium L. (Cornaceae)

2021 ◽  
pp. 2745-2749
Author(s):  
Lavanya D ◽  
Pooja Rao ◽  
Soundarya S ◽  
Surabhi T.S ◽  
Prashith Kekuda T.R
Keyword(s):  
Antioxidant Activity ◽  
Leaf Extract ◽  
Antioxidant Activities ◽  
Diffusion Method ◽  
Fruit Extract ◽  
Medicinal Uses ◽  
Fruit Extracts ◽  
The Family ◽  
Reducing Activity ◽  
Antibacterial And Antifungal

Objectives: Alangium salviifolium L. is one of the medicinally important plant belonging to the family Cornaceae. The present study evaluates antibacterial, antifungal and antioxidant activity of leaf and fruit extracts of A. salviifolium. Methods: Extraction of shade dried and powdered leaf and fruit was carried out by maceration technique. Antibacterial and antifungal activity was evaluated by agar well diffusion method and poisoned food technique, respectively. Antioxidant activity was determined by antiradical (DPPH and ABTS assays) and ferric reducing assays. Results: Both leaf and fruit extracts displayed inhibitory activity against test bacteria. Fruit extract was shown to be more effective against test bacteria when compared to leaf extract. Leaf extract was more effective in causing inhibition of mycelial growth of test fungi when compared to fruit extract. Both leaf and fruit extracts scavenged DPPH and ABTS radicals dose dependently and exhibited ferric reducing activity. Conclusions: The results of the present study indicated the potential of leaf as well as fruit of A. salviifolium to exhibit antimicrobial and antioxidant activities which justifies the traditional medicinal uses of the plant.

PENGARUH PEMBERIAN KONSENTRASI BIOINSEKTISIDA DAUN DAN BIJI MIMBA (Azadirachta indica) TERHADAP KEMATIAN ULAT GRAYAK (Spodoptera litura)

2018 ◽  
Vol 10 (02) ◽  
Author(s):  
P. S. Ajiningrum ◽  
I. A. K. Pramushinta
Keyword(s):  
Spodoptera Litura ◽  
Leaf Extract ◽  
Final Analysis ◽  
Seed Extract ◽  
Mortality Data ◽  
Botanical Insecticide ◽  
Nutritional Content ◽  
Variant Analysis ◽  
The Tropics ◽  
Army Worm

Red spinach (Alternanthera amoena) is one of the vegetable commodities that many people in demand for consumption because of its high nutritional content. Efforts to increase the production of red spinach often experience various obstacles. The main obstacle that limits the productivity of red spinach in the tropics is the number of Plant Disturbing Organisms  in the form of pests and potential diseases that can attack and decrease the production of spinach. One of the pests that often attack spinach is the existence of army worm (Spodoptera litura F.). Therefore, farmers need a way to eradicate the pest. This research is experimental using Random Complete Group. The data obtained were analyzed with variant analysis (ANOVA) in one direction and continued with LSD (Least Significant Different) test. Provision of botanical insecticide done by spraying the extract of leaves and seeds mimba with concentration dose 0%, 5%, 10% and 15%. In the final analysis of mortality data of army worm (Spodoptera litura F.) treated with mimba leaf extract obtained significant value of 76.263 at a significant level of 0.05 so it can be concluded that there is influence of mimba leaf extract on mortality of army worm. In the final analysis of mortality data of army worm (Spodoptera litura F.) treated with mimba seed extract obtained significant value of 78.625 at a significant level of 0.05 so it can be concluded that there is an effect of mimba seeds extract on mortality army worm.   Keywords: mimba leaf extract,  mimba seed extract, red spinach (Alternanthera amoena), army worm (Spodoptera litura F.), botanical insecticide

Aqueous extracts of avocado pear (Persea americana Mill.) leaves and seeds exhibit anti-cholinesterases and antioxidant activities in vitro

2016 ◽  
Vol 27 (2) ◽  
Author(s):  
Ganiyu Oboh ◽  
Veronica O. Odubanjo ◽  
Fatai Bello ◽  
Ayokunle O. Ademosun ◽  
Sunday I. Oyeleye ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Inhibitory Effect ◽  
Seed Extract ◽  
Persea Americana ◽  
Dependent Manner ◽  
Natural Treatment

AbstractAvocado pear (The inhibitory effects of extracts on AChE and BChE activities and antioxidant potentials (inhibition of FeThe extracts inhibited AChE and BChE activities and prooxidant-induced TBARS production in a dose-dependent manner, with the seed extract having the highest inhibitory effect and the leaf extract exhibiting higher phenolic content and radical scavenging abilities, but lower Fe chelation ability compared with that of the seed. The phytochemical screening revealed the presence of saponins, alkaloids, and terpenoids in both extracts, whereas the total alkaloid profile was higher in the seed extract than in the leaf extract, as revealed by GC-FID.The anti-cholinesterase and antioxidant activities of avocado leaf and seed could be linked to their phytoconstituents and might be the possible mechanisms underlying their use as a cheap and natural treatment/management of AD. However, these extracts should be further investigated in vivo.

Storage stability of yoghurts enriched with coriander (Coriandrum sativum l.) seeds extract

Food Research ◽  
2021 ◽  
Vol 5 (4) ◽  
pp. 179-190
Author(s):  
Q.Y. Jameel ◽  
N.K. Mohammed
Keyword(s):  
Storage Stability ◽  
Chemical Properties ◽  
Acid Value ◽  
Seed Extract ◽  
Sensory Properties ◽  
Natural Food ◽  
Food Preservative ◽  
Milk Products ◽  
Sensory Evaluations ◽  
Coriander Seed

This study was aimed to estimate the effects of the extract of coriander seed during storage on the chemical and sensory properties of yoghurt. Coriander seed extract was incorporated into yoghurt at different concentrations, 18 mg/mL (T1C1), 36 mg/mL (T2C2) and 54 mg/mL (T3C3) respectively, while control was performed using a sample without extract (T0C0). Samples were stored at 4°C for 42 days and every seven days were evaluated. For all samples containing extract, the values of lactose, fat, pH, protein, tyrosine, acid degree value, acid value, free fatty acid and sensory properties gave higher scores than those of yoghurt without extract. A major deterioration beyond 28 days of storage due to high acidity and an unpleasant taste was discovered by chemical and sensory evaluations of the yoghurt without plant extract. On the other hand, concentrations of 18, 36 and 54 mg/mL had shown to have a remarkable 42-day preservation activity in yoghurt. Compared to formulas T1C1 and T2C2, which contained 18 mg/mL and 36 mg/ mL respectively, formula T3C3, fortified with coriander seed extract at 54 mg/mL, had the highest value in maintaining the chemical properties of yoghurt after 42 days. The findings indicated that coriander extract can be applied as a natural food preservative to milk products in order to increase stability during storage.

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