Evaluation changes in indicators of oncological service in breast cancer in Kazakhstan

2020 ◽  
Vol 1-2 (211-212) ◽  
pp. 16-20
Author(s):  
Nurbek Igissinov ◽  
◽  
Asem Toguzbayeva ◽  
Gulnur Igissinova ◽  
Zarina Bilyalova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Diagnosis ◽  
Breast Cancer Incidence ◽  
Stage Iv ◽  
Mortality Rates ◽  
International Agency ◽  
Crude Mortality Rate ◽  
Icd 10 ◽  
The Difference ◽  
The Republic

According to estimates from the International Agency for Research on Cancer (IARC) by 2040 the global burden is expected to grow to 3 million new breast cancer cases and 1 million cancer deaths of this cause. Studying the indicators of the oncological service for breast cancer allows us to identify and evaluate the effectiveness of mammological screening in Kazakhstan. Aim. Evaluate some indicators of the oncological service at breast cancer in Kazakhstan in 2009 to 2018. Material and methods. The research material was data from the Ministry of Health of the Republic of Kazakhstan - annual form No.7 and No.35 regarding breast cancer (ICD 10 C50) for 2009-2018. - morbidity, mortality, early diagnosis, neglect, morphological verification. A retrospective study using descriptive and analytical methods of biomedical statistics was used as the main method. Results and discussion. For 2009-2018, 40,199 new cases of breast cancer were registered in the republic for the first time and 12,971 women died from this disease. The average annual crude incidence rate of breast cancer was 45.4±1.40/0000 (95% CI=42.8-48.1) and increased in dynamics from 39.5±0.70/0000 (2009) to 49.6±0.70/0000 in 2018, the difference was statistically significant (t=10.2 and p=0.000). In dynamics, mortality rates from breast cancer tended to statistically significant (t=7.95 and p=0.000) decrease from 16.5±0.40/0000 (2009) to 12.0±0.40/0000 in 2018 year, and the average annual crude mortality rate from breast cancer was 14.8 0.50/0000 (95% CI=13.7-15.8). The indicators of early diagnosis (the proportion of patients with stage I-II) improved from 71.1% (2009) to 87.6% in 2018, the proportion of patients with stage III decreased (from 22.2% to 8.6 %) and stage IV (from 6.4% to 3.6%) for the studied years, i.e. neglect rates are declining. The indicators of morphological verification in breast cancer have always been high and over the studied years improved from 93.4% to 99.1%. Conclusion. An analysis of the indicators of the oncological service at breast cancer revealed an improvement in morphological verification and early diagnosis, a decrease in neglect and mortality rates, which is undoubtedly associated with ongoing anti-cancer measures in Kazakhstan, which a regularly mammological screening. Keywords: breast cancer, incidence, mortality, early diagnosis, neglect, morphological neglect.

Evaluation changes in indicators of oncological service in gastric cancer in Kazakhstan

2020 ◽  
Vol 1-2 (211-212) ◽  
pp. 21-25
Author(s):  
Rustem Taszhanov ◽  
◽  
Nurbek Igissinov ◽  
Saken Kozhakhmetov ◽  
Sarsenbi Koblandin ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Diagnosis ◽  
Stage Iv ◽  
Specific Weight ◽  
Mortality Rates ◽  
International Agency ◽  
Anti Cancer ◽  
Keywords Gastric Cancer ◽  
The Difference ◽  
The Republic

About 1.8 million new cases of gastric cancer (GC) are predicted and it is expected that about 1.4 million human will die from this pathology, according to the forecasts of the International Agency for Research on Cancer in 2040. To this aim, an analysis studying the indicators of the oncological service for GC also makes it possible to evaluate the ongoing anti-cancer measures in the Republic of Kazakhstan. Aim. Evaluate some indicators of the oncological service at GC in Kazakhstan in 2009 to 2018. Material and methods. The research material was data from the Ministry of Health of the Republic of Kazakhstan – annual form No. 7 and 35 regarding GC (ICD 10-C50) for 2009 2018 – incidence, mortality, early diagnosis, neglect, morphological verification. A retrospective study using descriptive and analytical methods of biomedical statistics was used as the main method. Results and discussion. For 2009-2018, 27,468 new cases of GC were registered in the republic for the first time and 19,672 deaths from this pathology were registered. The average annual crude incidence rate of GC was 16.1±0.20/0000 (95% CI=15.7-16.5) and decreased in dynamics from 16.8±0.30/0000 (2009) to 15.1±0.30/0000 in 2018, the difference was statistically significant (t=4.01 and p=0.000). In dynamics, mortality rates from GC tended to statistically significant (t=12.02 and p=0.000) decrease from 14.0±0.30/0000 (2009) to 8.9±0.20/0000 in 2018 year, and the average annual crude mortality rate from GC was 11.6±0.60/0000 (95% CI=10.5-12.7). The research of the study period reveals a trend: early diagnosis indicators (specific weight of patients with I-II stage) improved from 24.5% (2009) to 41.3% in 2018, and accordingly the specific weight of neglected patients significantly decreased with stage III (from 46.2% to 41.1%) and with stage IV (from 29.3% to 17.5%). The morphological verification indicators for GC over the studied years improved from 85.1% to 95.0%. Conclusion. An analysis of the indicators of the oncological service in GC revealed an improvement in morphological verification and early diagnosis, a decrease in neglect and mortality rates, which is undoubtedly associated with ongoing anti-cancer measures in Kazakhstan, in particular with the screening, which was carried out in 2012-2016. Keywords: gastric cancer, incidence, mortality, early diagnosis, neglect, morphological verification.

Evaluation Changes in Indicators of Oncological Service in Colorectal Cancer in East Kazakhstan Region

2021 ◽  
Vol 9-10 (219-220) ◽  
pp. 11-16
Author(s):  
Yerkezhan Zhadykova ◽  
◽  
Sauirbay Sakhanov ◽  
Dulat Turebayev ◽  
Dariyana Kulmirzayeva ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Mortality Rate ◽  
Early Diagnosis ◽  
Stage Iv ◽  
International Agency ◽  
Keywords Colorectal Cancer ◽  
Anti Cancer ◽  
East Kazakhstan ◽  
The Difference ◽  
The Republic

About 3.15 million new cases of colorectal cancer (CRC) are predicted and it is expected that about 1.62 million human will die from this pathology, according to the forecasts of the International Agency for Research on Cancer in 2040. To this aim, an analysis studying studying the indicators of the oncological service for CRC also makes it possible to evaluate the ongoing anti-cancer measures in East Kazakhstan region. Aim. Evaluate some indicators of the oncological service at CRC in East Kazakhstan region in 2009 to 2018. Materials and methods. The research material was data from the Ministry of Health of the Republic of Kazakhstan – annual form No. 7 and 35 regarding CRC (ICD 10 – C18-21) for 2009-2018 in East Kazakhstan region – incidence, mortality, early diagnosis, neglect, morphological verification. A retrospective study using descriptive and analytical methods of biomedical statistics was used as the main method. Results and discussion. For 2009-2018, 3,661 new cases of CRC were registered in East Kazakhstan region for the first time. The incidence of CRC was 25.30/0000 and in dynamics tended to increase from 21.90/0000 (2009) to 25.70/0000 in 2018, the difference was statistically significant (t=1.99 and p=0.047). The mortality rate from CRC tended to decrease from 15.50/0000 to 14.70/0000 (p=0.591), and the average annual mortality rate from CRC was 15.60/0000. The indicators of early diagnosis (the proportion of patients with stage I-II) improved from 58.8% (2009) to 62.3% in 2018, and, accordingly, the indicators of the proportion of neglected patients significantly decreased with stage III (from 25.5% to 20.8%), while with stage IV (from 15.7% to 16.9%) there is a slight increase. The indicators of morphological verification in CRC improved from 90.5% to 98.6% during the studied years. Conclusion. An improvement in the indicators of morphological verification and early diagnosis of CRC was found. The obtained results are recommended to be used for monitoring anti-cancer measures in the region. Keywords: colorectal cancer, incidence, mortality, early diagnosis, neglect, morphological verification.

scholarly journals Changes in the assessments of cancer service indicators in cervical cancer in Kazakhstan

2020 ◽  
Vol 56 (2) ◽  
pp. 12-15
Author(s):  
N. S. IGISSINOV ◽  
Zh. B. TELMANOVA ◽  
G. S. IGISSINOVA ◽  
Z. A. BILYALOVA ◽  
D. M. KULMIRZAYEVA
Keyword(s):  
Cervical Cancer ◽  
Early Diagnosis ◽  
Stage Iv ◽  
Specific Weight ◽  
Mortality Rates ◽  
International Agency ◽  
Cancer Service ◽  
Anti Cancer ◽  
The Republic ◽  
Biomedical Statistics

About 800 thousand new cases of cervical cancer (CC) are predicted, and it is expected that about 460 thousand women will die from this pathology, according to the forecasts of the International Agency for Research on Cancer in 2040. To this aim, an analysis studying the indicators of the cancer service for CC also allows us to evaluate the effectiveness of anti-cancer measures in the Republic of Kazakhstan. Aim: Evaluate some indicators of the cancer service at CC in Kazakhstan for 2009-2018. Materials and methods. The research material was data from the Ministry of Health of the Republic of Kazakhstan – annual form No.7 and 35 regarding CC (ICD10–C53) for 2009-2018 – incidence, mortality, early diagnosis, neglect, morphological verification. A retrospective study using descriptive and analytical methods of biomedical statistics was used as the main method. Results and discussion. For 2009-2018, 16,441 new cases of CC were registered in the Republic for the first time, and 6,461 women died from this disease. The crude CC incidence rate increased from 16.3±0.4‰ (2009) to 19.5±0.5‰ in 2018 (p=0.000). In dynamics, mortality rates from CC tended to decrease from 8.4±0.3‰ (2009) to 6.4±0.3‰ in 2018 (р=0.000). The research of the study period reveals a trend: early diagnosis indicators (specific weight of patients with I-II stage) improved from 79.8% (2009) to 88.1% in 2018, and accordingly the specific weight of neglected patients significantly decreased with stage III (from 15.4% to 8.9%) and with stage IV (from 3.4% to 2.7%). The morphological verification indicators for CC remained virtually unchanged, remaining fairly high 99.2% and 99.3%, respectively, in 2009 and 2018. Conclusion. An analysis of the indicators of the cancer service in CC revealed an improvement in morphological verification and early diagnosis, a decrease in neglect and mortality rates, which is undoubtedly associated with regular anti-cancer activities in Kazakhstan, in particular CC screening.

Spatial assessment of breast cancer mortality in Kazakhstan

2020 ◽  
Vol 1-2 (211-212) ◽  
pp. 26-30
Author(s):  
Asem Toguzbayeva ◽  
◽  
Nurbek Igissinov ◽  
Gulnur Igissinova ◽  
Zarina Bilyalova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Mortality ◽  
Breast Cancer Mortality ◽  
Monitoring And Evaluation ◽  
Mortality Rates ◽  
Female Population ◽  
Spatial Assessment ◽  
The North ◽  
Icd 10 ◽  
The Republic

Breast cancer (BC) mortality analysis at the regional level is important not only for assessing the current epidemiological situation, but also contributes to a better understanding of factors that may affect mortality. Aim. The purpose of the study is to assess the spatial deaths from BC in Kazakhstan. Material and methods. Investigation was retrospective between 2009-2018 years. The materials were collected by statistics Committee by the Ministry of National Economy of the Republic of Kazakhstan concerning the deaths from BC (ICD-10-C50). A method of compiling a cartogram based on the determination of the standard deviation (σ) from the mean (x) was applied. Mortality rates calculated per 100,000 female population were used. Results and discussion. A spatial assessment of breast cancer mortality was presented based on the calculation of mortality rates: low up to 12.80/0000; average from 12.8 to 17.30/0000, and high – above 17.30/0000. It was established that the North Kazakhstan (18.20/0000), Akmola (18.90/0000), East Kazakhstan (20.30/0000) and Pavlodar (22.20/0000) regions, as well as the city of Almaty (21.70/0000) relate to regions with high mortality rates. Conclusion. Features of mortality from BC in the republic have been established, while a spatial assessment (cartogram) of mortality indicates regions with different mortality rates. The obtained data are recommended to be used for monitoring and evaluation of anti-cancer measures – BC screening. Keywords: mortality, breast cancer, cartogram, Kazakhstan.

Breast cancer incidence and mortality rates in native and alien populations of the Republic of Buryatia

2019 ◽  
Vol 22 (2) ◽  
pp. 62
Author(s):  
L. F. Pisareva ◽  
N. P. Lyakhova ◽  
D. A. Perinov ◽  
E. V. Panferova ◽  
A. V. Doroshenko ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Breast Cancer Incidence ◽  
Mortality Rates ◽  
Incidence And Mortality ◽  
The Republic

Breast Cancer

2018 ◽  
Author(s):  
Nancy E Davidson
Keyword(s):  
Breast Cancer ◽  
United States ◽  
Cancer Incidence ◽  
Hormone Replacement ◽  
Breast Cancer Incidence ◽  
Stage Iv ◽  
The United States ◽  
Rate Of Increase ◽  
Stage Iv Breast Cancer ◽  
Incidence And Mortality

Invasive breast cancer, the most common nonskin cancer in women in the United States, will be diagnosed in 266,120 In 2018, along with 63,960 new cases of non-invasive (in situ) breast cancer. Incidence and mortality reached a plateau and appear to be dropping in both the United States and parts of western Europe. This decline has been attributed to several factors, such as early detection through the use of screening mammography and appropriate use of systemic adjuvant therapy, as well as decreased use of hormone replacement therapy. However, the global burden of breast cancer remains great, and global breast cancer incidence increased from 641,000 in 1980 to 1,643,000 in 2010, an annual rate of increase of 3.1%. This chapter examines the etiology, epidemiology, prevention, screening, staging, and prognosis of breast cancer. The diagnoses and treatments of the four stages of breast cancer are also included. Figures include algorithms used for the systemic treatment of stage IV breast cancer and hormone therapy for women with stage IV breast cancer. Tables describe selected outcomes from the National Surgical Adjuvant Breast and Bowel Project (NSABP) P-1 and P-2 chemoprevention trials, tamoxifen chemoprevention trials for breast cancer, the TNM staging system and stage groupings for breast cancer, some commonly used adjuvant chemotherapy regimens, an algorithm for suggested treatment for patients with operable breast cancer from the 2011 St. Gallen consensus conference, guidelines for surveillance of asymptomatic early breast cancer survivors from the American Society of Clinical Oncology, and newer agents for metastatic breast cancer commercially available in the United States. This review contains 2 highly rendered figures, 8 tables, and 108 references.

scholarly journals Breast Cancer Research in the Caribbean: Analysis of Reports From 1975 to 2017

2018 ◽  
pp. 1-21 ◽  
Author(s):  
Camille Ragin ◽  
Rishika Banydeen ◽  
Christine Zhang ◽  
Athena Ben ◽  
Victoria Calabrese ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Incidence ◽  
Mortality Rates ◽  
The Body ◽  
Cancer Registration ◽  
Future Research ◽  
Caribbean Women ◽  
Incidence And Mortality ◽  
High Incidence ◽  
The Caribbean

Purpose Breast cancer is among the leading causes of death resulting from cancer in Caribbean women. Studies examining exogenous and genetically predetermined endogenous risk factors are critical to define breast cancer susceptibility in Caribbean women. The purpose of this systematic review is to assess the existing scientific literature in the last 42 years (1975 to 2017) to describe the body of research generated for the population of this region and determine future research directions. Methods We selected published research articles using a combination of definite keyword searches in PubMed. Only articles presenting the Caribbean population as the focus of their research objectives were included in this analysis. Results Studies on breast cancer in the Caribbean are limited. A majority of publications on Caribbean populations were descriptive, focusing on cancer trends and clinicopathologic factors. High incidence and mortality rates for breast cancer are reported for the region, and there seem to be some differences between countries in the frequency of cases according to age at presentation. A limited number of epidemiologic, behavioral, and genetic and molecular studies were conducted in more recent years. Conclusion A regional strategy for cancer registration is needed for the Caribbean to address possible underestimates of breast cancer incidence. Furthermore, behavioral, molecular, genetic, and epidemiologic investigations of breast cancer are critical to address the concerns related to currently described high incidence and mortality rates in the Caribbean.

scholarly journals International Variation in Female Breast Cancer Incidence and Mortality Rates

2015 ◽  
Vol 24 (10) ◽  
pp. 1495-1506 ◽  
Author(s):  
Carol E. DeSantis ◽  
Freddie Bray ◽  
Jacques Ferlay ◽  
Joannie Lortet-Tieulent ◽  
Benjamin O. Anderson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Breast Cancer Incidence ◽  
Mortality Rates ◽  
Female Breast Cancer ◽  
International Variation ◽  
Female Breast ◽  
Incidence And Mortality

scholarly journals Mapping of Female Breast Cancer Incidence and Mortality Rates to Socioeconomic Factors: From Univariate Analysis to Path Diagram Analysis

2020 ◽  
Author(s):  
Qiongle Peng ◽  
Xiaoling Ren ◽  
Bing Cui ◽  
Henggui Cui
Keyword(s):  
Breast Cancer ◽  
Socioeconomic Factors ◽  
Univariate Analysis ◽  
Breast Cancer Incidence ◽  
Mortality Rates ◽  
Female Breast Cancer ◽  
Economic Wealth ◽  
Female Breast ◽  
Path Coefficients ◽  
Incidence And Mortality

Abstract PURPOSE: Breast cancer is the leading cause of death in females around the world. Its occurrence and development has been linked to genetic factors, living habits and health conditions, but also by socioeconomic factors. Comparisons of incidence and mortality rates of female breast cancer are useful approaches to define cancer-related socioeconomic disparities. METHODS: International Agency for Research on Cancer's CANCERMondial clearinghouse was used to determine the incidence and mortality rates of female breast cancer data from several developed countries for 1980–2012. We subsequently investigated the effects of socioeconomic factors on breast cancer incidence and mortality rates by regression methods from univariate analysis to path diagram analysis. RESULTS: The relationship between socioeconomic factors and the occurrence and development of breast cancer did not follow a monotonic function. We found a positive, significant association of national public wealth (GDP) on the incidence and mortality of breast cancer. The path coefficients in the structuralequations model are -0.51 and -0.39, respectively. In addition to the significant relationship between individual physical and psychological characteristics, social pressure, such as unemployment rate (UR) has a significant impact on the incidence and mortality of breast cancer. The path coefficients in the structural equations model are all 0.2. The path coefficients of individual economic wealth to the incidence rate and mortality rate of breast cancer is 0.18 and 0.27, respectively. CONCLUSIONS: A significant statistical relationship between the socioeconomic development and the crude rates of female breast cancer was shown in this study. The incidence and mortality rates of breast cancer can be regulated effectively by a moderate increase in GDP, and clearly was affected by the individual’s economic wealth (GDPPC). In addition, the influence of social pressure (e.g., unemployment rate) on the incidence and mortality of breast cancer was not typical monotonous. The survival rate of breast cancer determined by the ratio of mortality rate to incidence rate also showed a similar pattern with socioeconomic factors.

scholarly journals Screening and Early Diagnosis of Breast Cancer: Assessment of Knowledge and Practical Abilities of Final Year Nursing and Midwifery Students in Health Schools of Ouagadougou

2017 ◽  
Vol 2 (3) ◽  
pp. 47
Author(s):  
Nayi Zongo ◽  
Sanon/Lompo Marthe Sandrine ◽  
Bambara H. Aboubacar ◽  
Soma Chantal ◽  
Bambara Augustin Tozoula ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Diagnosis ◽  
Clinical Signs ◽  
Study Data ◽  
P Value ◽  
Screening Methods ◽  
Breast Cancers ◽  
Chi Square ◽  
Cross Sectional ◽  
The Difference

The Objective was to assess the knowledge and practical abilities of final year nursing and midwifery students in health schools of Ouagadougou relating to screening and early diagnosis of breast cancer. This is a cross-sectional, prospective and descriptive observational study conducted from 1st November 2014 to 31st January 2015. A sample of 403 students was used for this study. Data were collected using an individual questionaire and were typed on Epi data and then analyzed on SPSS software. Chi-square tests were used to compare the different proportions. The difference is considered to be significant if p value < 0.05. Three hundred and ninety nine students filled the questionnaire, i.e. a rate of non-respondents of 1%. All students were aware of the existence of breast cancer. The media (47.8%) was the main source of information. The level of knowledge of students was satisfactory with frequencies of 83.9% for risk factors; 91.6% for clinical signs; 83.4 % for screening methods and 88.1% for therapeutic terms of breast cancers. However, focus should be put on the teaching of cancerology and the supervision of students during internship, must be reinforced. These results attest that the level of students in the knowledge and practical abilities concerning screening and early diagnosis of breast cancer is satisfactory.

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