Optimization of diagnostic system of hand diseases in employees working under combined effects of vibration and physical overloads

2019 ◽  
pp. 950-955
Author(s):  
M. M. Poroshina ◽  
E. M. Vlasova ◽  
A. Ya. Perevalov
Keyword(s):  
Working Conditions ◽  
Comparison Group ◽  
Clinical Manifestations ◽  
Diagnostic System ◽  
Pain Syndrome ◽  
Observation Group ◽  
Combined Effects ◽  
X Rays ◽  
Industrial Enterprises ◽  
Special Assessment

The results of research carried out by theFederalScientificCenterfor Medical and Preventive Technologies of Public Health Risk Management Technologies for the period 2013–2018 showed that diseases associated with the combined effects of vibration and physical overload, employees of hazardous industries develop with experience of 15 years or more. The risk group is women older than 35 years and men older than 40 years. Pathology at the stage of detailed clinical manifestations is characterized by persistent pain syndrome, and, as a consequence, a decrease in the ability to work of workers.The aim of the study was to optimize the system of diagnosis of hand diseases in workers of industrial enterprises engaged in labor activities under the combined effects of vibration and physical overload, for the development of primary prevention programs.The observation group consisted of 32 employees aged 39.3±4.3 years, with an experience of 17.4±4.3 years; the comparison group consisted of 30 employees whose working conditions are not related to the studied factors; the average age was 40.6±3.4 years, experience was 19.1±3.1 years. The examination included analysis of the results of a special assessment of working conditions; assessment of neurological status; functional tests; laboratory studies (assessment of inflammation), hand dynamometry, stimulation electroneuromyography; x-rays of the hands and wrist joints, ultrasound examination of the hands.More than half of the surveyed persons of the observation group and 3/4 of the workers of the comparison group did not make complaints. Indicators of dynamometry of workers in both groups corresponded to physiological norm (p>0.05). Analysis of the results of dynamometer with data from previous years of PMO showed a decrease in strength of muscles of the hand leading hands on 2je,0–16. 7% and from 83.3% of the employees of the monitoring group and in 44.4% of the comparison group (p<0.05), in 50 % of the cases there was a decrease in the percentage of changes in the hand force variation (HFV) in the observation group, and in 38.9% of the cases the indicators remained unchanged. According to ultrasound of the hands, signs of tendinopathy were established in 85% of the employees of the observation group in the absence of persons with similar changes in the comparison group.In order to optimize the diagnosis of diseases of the hand in industrial workers who carry out their work under the combined effects of vibration and physical overload, in the case of a decrease in the rate of carpal dynamometry by 5% or more during the year, it is recommended to conduct ultrasound of the tendon-ligamentous apparatus of the hand, which will allow timely identification of early signs of tendinopathy.

scholarly journals Features of metabolic disorders in chromium mine workers

2021 ◽  
Vol 100 (10) ◽  
pp. 1095-1102
Author(s):  
Nina V. Zaitseva ◽  
Vitalii G. Kostarev ◽  
Konstantin P. Luzhetskiy ◽  
Alexander E. Nosov ◽  
Olga Yu. Ustinova ◽  
...  
Keyword(s):  
Working Conditions ◽  
Metabolic Disorders ◽  
Comparison Group ◽  
Visceral Obesity ◽  
Endocrine System ◽  
Atherogenic Index ◽  
Observation Group ◽  
Accumulation Coefficient ◽  
Noise Vibration ◽  
Metabolic Indices

Introduction. Working conditions, clinical and laboratory status of 236 workers of a chromium mine were investigated. Materials and methods. The observation group included 162 underground employees working in conditions of the combined impact of negative occupational factors (dust, noise, vibration, tension and severity there, cooling microclimate) - class 3.3-3.4. The comparison group included 74 mine employees working in acceptable working conditions - class 2. Results. In the observation group, the pathology of the cardiovascular and endocrine system (ICD-10: I00-I99, E00-E07) was detected 2.8-3.3 times more often (p = 0.001-0.02), the relative risk of disease formation was 2.7-3.2 times higher than in the comparison group (RR = 2.7-3.2; DI = 1.44-9.2; p = 0.001-0.02). Under the conditions of the combined effect of negative production factors, as features of metabolic disorders, it was noted that the most unfavourable - abdominal form of obesity was diagnosed 1.4 times more often (42.0%, p = 0.013), the atherogenic index was 1.2 times higher, and the level HDL is 1.2 times lower than in the comparison group (p = 0.017-0.047); “Metabolic indices” - lipid accumulation coefficient (LAP) and visceral obesity index (VAI) were 1.2-1.4 times higher than the values in the comparison group (p = 0.001-0.048). Conclusions. To implement a complex of medical and preventive measures aimed at increasing life expectancy and working longevity, early prevention of CVD, including among those working in the extraction of chrome ore, it is advisable to consider the introduction of the calculation of early markers of metabolic disorders - VAI and LAP indices in the medical examination programs.

scholarly journals Features of pain syndrome in genital endometriosis and migraine

2021 ◽  
Vol 13 (1) ◽  
pp. 31-37
Author(s):  
U. A. Bagirova ◽  
E. G. Chernukha ◽  
E. G. Filatova
Keyword(s):  
Chronic Migraine ◽  
Pelvic Pain ◽  
Comparison Group ◽  
Clinical Manifestations ◽  
Interdisciplinary Approach ◽  
Pain Syndrome ◽  
Episodic Migraine ◽  
Leading Role ◽  
Clinical Neurological Examination

Migraine is often concurrent with endometriosis; however, the mechanisms of comorbidity of these conditions are inadequately studied. Pain is considered as the most significant clinical symptom and maladaptive manifestation of both migraine and endometriosis. Studying the relationship between the clinical manifestations of pain syndrome in patients with endometriosis and migraine is important, since it will contribute to the understanding of the mechanisms of comorbidity of these diseases.Objective: to analyze the features of pain syndrome in patients with migraine and genital endometriosis to clarify the neurogenic mechanisms of their comorbid relationship.Patients and methods. A total of 125 patients who had gone to a gynecologist for endometriosis were examined for the presence of migraine. In accordance with the inclusion criteria, 79 patients (mean age, 34.68±7.11 years) with genital endometriosis confirmed by diagnostic laparoscopy participated in the further study. Two age-matched groups were formed: a study group consisted of 38 patients with endometriosis and concomitant migraine; a comparison group included 41 patients with endometriosis without migraine. All the patients underwent clinical neurological examination, questionnaire survey, pelvic ultrasound, assessment of the severity of pelvic pain according to the pelvic pain index, and determination of the level of central sensitization (CS) using the CS Inventory.Results and discussion. 42% out of the 125 patients who had visited their gynecologist for endometriosis suffered from concomitant migraine, which confirms the comorbidity of these diseases. Chronic pelvic pain (CPP), dysmenorrhea, dyspareunia, and dyschesia were more common in patients with endometriosis and migraine; there were more patients with asymptomatic endometriosis in the comparison group. The patients of the two groups did not differ in the presentation of different forms of endometriosis, which favors the leading role of central mechanisms in the pathogenesis of pain syndrome in comorbidity of these diseases.In addition, there was a statistically significant increase in the presentation of CPP and dysmenorrhea in patients with chronic migraine compared to those with episodic migraine and to those without migraine. Significantly higher levels of CS according to CSI and pelvic pain index were found in patients with chronic migraine and endometriosis, which suggests that CS plays a key role in the comorbidity of these diseases.Conclusion. The phenomenon of CS is one of the mechanisms of comorbidity of migraine and endometriosis, contributes to both the worsening of various painful manifestations of endometriosis and the increase in migraine attacks, thereby causing obvious maladaptation in patients. The role of CS in the comorbidity of migraine and endometriosis opens up possibilities for the elaboration of a comprehensive interdisciplinary approach to treating these diseases.

scholarly journals Clinical and functional features in course chronic pancreatitis with accompanying duodenostasis

2017 ◽  
Vol 38 (4) ◽  
pp. 40-44
Author(s):  
Y. M. Vahrushev ◽  
A. A. Lebedev
Keyword(s):  
Chronic Pancreatitis ◽  
Comparison Group ◽  
Clinical Course ◽  
Pain Syndrome ◽  
Exocrine Pancreatic Function ◽  
Endocrine Function ◽  
Observation Group ◽  
X Ray ◽  
Functional Features ◽  
Functional Investigation

The aim is to research the clinical features, functional state of duodenum among patients with chronic pancreatitis and accompanying duodenostasis. Materials and methods. The clinical course of chronic pancreatitis with accompanying duodenostasis (85 cases) and isolated chronic pancreatitis (56 cases) has been studied. Along with the general clinical data the study includes the results of exocrine pancreatic function examination (fecal elastase-1, blood alpha amylase and lipase) and its endocrine function (insulin and С-peptide). Regulating hormonal factors (gastrin and somatotropin) have been studied. Results of X-ray and endoscopic examinations, intraduodenal manometry results were used in verification of duodenostasis. Results. In the observation group resistant pain syndrome was revealed in 93% cases (in patients with isolated pancreatitis in 57% cases) with more expressed coprological syndromes (amilorhea in 82.29%, creatorhea in 82.14%, steatorhea in 87.5% cases). In the observation group hyperperistaltic (in 88% cases of observation group and in 9.4% cases of the comparison group) and duodenal hypertension (in 22% cases of observation group and in 0.0% cases of the comparison group) were significantly more diagnosed. The phenomenon of «semolina» was revealed more frequently in observation group (in 31.9% cases of observation group and in 5% cases of the comparison group). Among patients with chronic pancreatitis and accompanying duodenostasis the level of C-peptid decreased, while secretion of insulin, somatotropin and gastrin increased. Conclusion. It reveals that according to the comprehensive clinical and functional investigation chronic pancreatitis with accompanying duodenostasis gets a more severe course in comparison with isolated pancreatitis.

scholarly journals Analysis of comorbid pathology in oil producers

2021 ◽  
Vol 100 (5) ◽  
pp. 464-470
Author(s):  
Olga Y. Ustinova ◽  
Nina V. Zaitseva ◽  
Vitalii G. Kostarev ◽  
Elena M. Vlasova ◽  
Alyona A. Vorobyova ◽  
...  
Keyword(s):  
Working Conditions ◽  
Work Experience ◽  
Oil And Gas ◽  
Comparison Group ◽  
Significant Risk ◽  
Oil Production ◽  
Gas Production ◽  
Observation Group ◽  
Oil And Gas Production ◽  
Average Work

Aim of the study. To analyze the patterns of the comorbidity pathology formation in employees occupied in oil production. Materials and methods. Observation group - 292 employees of the oil production enterprise (100% men). The average age was 39.4 ± 10.6 (20-65) years. Average work experience is 13.1 ± 9.6 (3-22) years. The comparison group included 65 employees working in the management of the enterprise. The average age is 40.2 ± 9.8 (20-65) years. Average work experience is 18.5 ± 9.5 (5-23) years. Observation group - 292 oil and gas production operators (OGP) - 100% men. The study involved a comprehensive research program, results analysis, and mathematical modeling. Results. It is typical for oil and gas production operators to be exposed to a complex impact of harmful production factors: industrial noise, the intensity of work, and physical overload combined with chemical factors. A prior occupational risk to the employees under mentioned working conditions was classified from low (moderate) risk to medium (significant) risk. The age of employees with developed comorbid pathology in the observation group was 31.7 ± 5.4 years, work experience in the specified working conditions was 4.6 ± 1.1 years; the age of workers in the comparison group was 35.4 ± 3.9 years, work experience was 7.4 ± 2.7 years. The results of functional studies have demonstrated a complex of abnormalities in workers with little expressed clinical symptomatology. Analysis of comorbid pathology showed an increase in n according to CIRS score, increasing the working experience among oil and gas operators. Conclusion. Comorbid pathology occurs in oil production workers within ten years of working experience under conditions of combined occupational and non-occupational factors. In the comorbid pathology development, both induced intrasystemic and intersystemic disorders significantly worsens the working life prognosis.

scholarly journals Clinical and functional features in course chronic pancreatitis with accompanying duodenostasis

2017 ◽  
Vol 38 (4) ◽  
pp. 40-44
Author(s):  
Y. M. Vahrushev ◽  
A. A. Lebedev
Keyword(s):  
Chronic Pancreatitis ◽  
Comparison Group ◽  
Clinical Course ◽  
Pain Syndrome ◽  
Exocrine Pancreatic Function ◽  
Endocrine Function ◽  
Observation Group ◽  
X Ray ◽  
Functional Features ◽  
Functional Investigation

  The aim is to research the clinical features, functional state of duodenum among patients with chronic pancreatitis and accompanying duodenostasis. Materials and methods. The clinical course of chronic pancreatitis with accompanying duodenostasis (85 cases) and isolated chronic pancreatitis (56 cases) has been studied. Along with the general clinical data the study includes the results of exocrine pancreatic function examination (fecal elastase-1, blood alpha amylase and lipase) and its endocrine function (insulin and С-peptide). Regulating hormonal factors (gastrin and somatotropin) have been studied. Results of X-ray and endoscopic examinations, intraduodenal manometry results were used in verification of duodenostasis. Results. In the observation group resistant pain syndrome was revealed in 93% cases (in patients with isolated pancreatitis in 57% cases) with more expressed coprological syndromes (amilorhea in 82.29%, creatorhea in 82.14%, steatorhea in 87.5% cases). In the observation group hyperperistaltic (in 88% cases of observation group and in 9.4% cases of the comparison group) and duodenal hypertension (in 22% cases of observation group and in 0.0% cases of the comparison group) were significantly more diagnosed. The phenomenon of «semolina» was revealed more frequently in observation group (in 31.9% cases of observation group and in 5% cases of the comparison group). Among patients with chronic pancreatitis and accompanying duodenostasis the level of C-peptid decreased, while secretion of insulin, somatotropin and gastrin increased. Conclusion. It reveals that according to the comprehensive clinical and functional investigation chronic pancreatitis with accompanying duodenostasis gets a more severe course in comparison with isolated pancreatitis.

Features of risk factors of development of the production caused pathology at workers of metallurgical production

2019 ◽  
pp. 926-930 ◽  
Author(s):  
E. M. Vlasova ◽  
E. A. Polevaya ◽  
M. M. Poroshina ◽  
M. I. Tiunova ◽  
V. B. Alekseev
Keyword(s):  
Risk Factors ◽  
Hydrogen Chloride ◽  
Metabolic Disorders ◽  
Comparison Group ◽  
Working Life ◽  
Observation Group ◽  
Industrial Enterprises ◽  
Production Factors ◽  
Respiratory Pathology ◽  
Chemical Factors

Introduction. The relevance of the study of cardiovascular diseases (CVD) as a production-related pathology in workers at industrial enterprises is due to the presence in the technological process of production factors (noise, general vibration, microclimate, severity of labor, chemical factors), potentially capable of provoking the development of CVD.The aim of the study was to assess respiratory and metabolic disorders, which are risk factors for CVD, in workers exposed to dust, chlorine and hydrogen chloride.Materials and methods. 139 patients working under the influence of dust, chlorine and hydrogen chloride were examined. Among the surveyed 74 women and 65 men. The comparison group (45 people) consisted of 20 women and 25 men who were not exposed to harmful factors of production during their working life.Results. In the group of workers exposed to occupational exposure to dust, chlorine and hydrochloride vapors, it was revealed that the proportion of workers with arterial hypertension was 33.3%, in the comparison group–17.6%, p<0.05 (RR 1.99; 95% CI 1.01–3.93; EF=47%; the degree of professional conditioning is average). The volume of forced exhalation per 1 second (FEV1) in the observation group was 3.18±0.14 l, and in the comparison group–4.1±0.20 l (p<0.001). The level of total cholesterol in the observation group was 5.72±0.13 mmol / l, and in the comparison group–5.16±0.23 mmol / l (p<0.05). The observation group showed a decrease in HDL (1.35±0.04 mmol / l vs. 1.64±0.10 mmol / l in the comparison group, p<0.05) and an increase in triglycerides (2.3±0.17 mmol/l versus 1.51±0.16 mmol/l in the comparison group, p<0.05).Conclusions. In the group of workers exposed to professional dust, chlorine and hydrochloride vapors, a decrease in the speed parameters of the external respiratory function, the development of proatherogenic metabolic disorders, and an increase in laboratory indicators of inflammation were revealed. These changes can lead to early manifestation of cardiovascular and respiratory pathology in this category of workers.

scholarly journals Comprehensive Analysis of Pain Syndrome in Patients With Mandibular Fractures Treated With Nucleo CMP Forte

2018 ◽  
Vol 45 (2) ◽  
pp. 25-30
Author(s):  
O. S. Barylo ◽  
S. S. Polishchuk ◽  
R. L. Furman ◽  
T. R. Zakalata ◽  
A. M. Yur
Keyword(s):  
Neuropathic Pain ◽  
Treatment Group ◽  
Comparison Group ◽  
Drug Product ◽  
Inferior Alveolar Nerve ◽  
Clinical Manifestations ◽  
Pain Syndrome ◽  
Nerve Damage ◽  
Mandibular Fractures ◽  
Dynamic Pattern

Abstract The objective of this study was to perform a comprehensive evaluation of major indices of pain syndrome in patients with mandibular fractures accompanied by damage of inferior alveolar nerve using conventional therapeutic regimen supplemented by the administration of drug product Nucleo CMP Forte. Operative and postoperative treatment of 50 patients with angular fractures of the mandible, accompanied by clinical manifestations of inferior alveolar nerve damage, was performed. The severity of pain syndrome and neuropathy symptoms was evaluated using the LANSS pain scale, DN4 questionnaire, the Visual Analogue Scale (VAS) and Neuropathy Total Symptom Scores (NTSS-9). Decrease of pain syndrome was revealed in both groups but with different dynamic pattern. In the treatment group pain syndrome manifestations and neuropathy symptoms decreased quicker than in the comparison group. As LANSS, DN4, VAS and NTSS-9 scales characterize pain syndrome from various perspectives, the results were different but similar tendency was shown. At the beginning of the study LANSS scale indices were nearly identical in both groups, while on the 7th and 14th day they were 1.35 and 2.03 times lower, respectively, in the treatment group compared to the control group. On the first day NTSS-9 scale values did not practically differ in between the studied patients, being somewhat higher in the treatment group. On the 7th and 14th day the values increased 1.24 and 3.82 times, in the treatment group and in the group of comparison, respectively. Thus, the patients in the treatment group showed significantly greater pain relief than those in the comparison group. The analysis of dynamic pattern of complaints as well as the objective findings in angular fractures of the mandible, accompanied by the damage of inferior alveolar nerve, demonstrated that the administration of drug product Nucleo CMP Forte led to a more pronounced improvement of pain syndrome in the course of treatment. Because of the fact that neuropathic pain can develop in orthodontic treatment, as well as when partial and complete removable dentures are used, the administration of drug product Nucleo CMP Forte is warranted in combined therapy of both mandibular fractures followed by the clinical manifestations of inferior alveolar nerve damage, and neuropathic pain management in orthodontics and orthopedic stomatology.

Early signs of upper limb lesions in workers exposed to local vibration

2019 ◽  
pp. 960-965
Author(s):  
Ju. A. Ivashova ◽  
E. A. Polevaya ◽  
T. A. Ponomareva
Keyword(s):  
Working Conditions ◽  
Upper Limb ◽  
Comparison Group ◽  
Average Length ◽  
Group Analysis ◽  
Observation Group ◽  
Years Of Experience ◽  
Local Vibration ◽  
Early Signs ◽  
The Impact

Vibration pathology, including disorders of the vascular, nervous and musculoskeletal systems, occupies one of the first places in the structure of health disorders in workers of vibration-hazardous industries.The aim of the study was to identify informative diagnostic criteria for identifying early signs of upper limb lesions.The observation group consisted of 90 workers aged 46.7±2.5 years (p>0.05), with experience of 22.4±3.9 years; the comparison group–60 workers whose working conditions were not associated with the studied factor; the average age of 45.8±2.4 years, experience of 24.1±4.1 years (p>0.05). The survey included the analysis of working conditions and professional route, clinical examination, questionnaires, laboratory and functional studies, statistical processing of the results, calculation of epidemiological indicators.The analysis of working conditions showed that the level of local vibration exceeded the maximum permissible level by 2–6 dB for the employees of the observation group. The survey showed that going to the doctor is a last resort for workers, even in the case of chronic pain. According to the results of the survey and examination, it was found that the formation of pain syndrome in employees of the observation group occurs against the background of the development of vascular and neurovascular disorders. There was an increase in the estimated age of the arteries of the upper extremities (5.3±2.8 years) in 23.3% of the observation group. Analysis of dynamometry results in dynamics for three years showed a slowly progressive decline in 21.1% of workers in vibration-hazardous professions with 11.3±3.4 years of experience, and only 3.3% of workers in the comparison group with 23.6±6.3 years of experience. In General, there is a high risk of decreased muscle strength, which is prognostically significant for the preservation of professional ability to work. The calculation of epidemiological indicators confirmed the connection of vasospastic reactions with the impact of local vibration (χ2=5.85, p<0.001; F=0.177, p<0.05; RR=2.5, 95% CI=1.7–3.7; EF=65%). Under the influence of local vibration, early signs of upper limb lesions develop with 5 years of experience and are characterized by vascular changes. Clinical syndromes characteristic of vibrational pathology are formed with an average length of service of 10 years. It is necessary to improve the complex of diagnostic measures aimed at identifying early signs of damage to the upper limbs, in order to improve the labor prognosis in workers under the influence of local vibration.

Endothelial dysfunction in workers in underground mining of chrome ores

2019 ◽  
pp. 914-919
Author(s):  
N. V. Zaitseva ◽  
A. E. Nosov ◽  
Ju. A. Ivashova ◽  
A. S. Baidina ◽  
V. G. Kostarev
Keyword(s):  
Shear Stress ◽  
Endothelial Dysfunction ◽  
Endothelial Function ◽  
Working Conditions ◽  
Brachial Artery ◽  
Comparison Group ◽  
Underground Mining ◽  
Relative Increase ◽  
Observation Group ◽  
Brachial Artery Diameter

Introduction. Currently, endothelial dysfunction is considered as one of the initial stages of the pathogenesis of cardiovascular diseases. By isolating a number of biologically active compounds, the endothelium helps to maintain vascular tone and physiological rheology of the blood. Modern production of chrome ore is characterized by a variety of harmful occupational factors (chromium, dust, noise, vibration, severity and intensity of work, cooling microclimate), which can disrupt the normal functioning of the vascular endothelium and lead to the development of cardiovascular diseases.The aim of the study was to study the features of endothelial function in workers engaged in underground mining of chrome ore in harmful working conditions.Materials and methods. The study included 98 miners of the enterprise for the extraction of chrome ore. The comparison group (working in conditions outside the influence of the studied production factors) consisted of 75 employees-managers and specialists of administrative and managerial personnel of the enterprise, comparable in age and experience with the observation group. To assess the vasomotor function of the endothelium, a flow-dependent (endothelium-dependent) vasodilation test was performed using the D. S. Celermajer technique. Post-occlusive increase in brachial artery diameter, brachial artery sensitivity coefficient to endothelial shift change were evaluated.Results. The endothelial function of mine workers did not differ significantly from the comparison group with work experience up to 10 years (the values of the relative increase in the diameter of the brachial artery 12.2% in the observation group and in the comparison group 12.6%, p=0.74). With experience of more than 10 years, the value of the relative increase in the diameter of the brachial artery in the observation group with experience of more than 10 years corresponded to the signs of endothelial dysfunction and amounted to 8.6%, while in the comparison group this figure was 12.4%, which corresponded to normal endothelial function (p=0.019). Endothelial function progressively deteriorated with increasing seniority in mine workers. Conclusions. For workers engaged in underground mining of chrome ore for more than 10 years, a reduced vasodilation reaction to reperfusion after an occlusion test and a low coefficient of sensitivity of the endothelium to shear stress are characteristic. There was no statistically significant decrease in increase in brachial artery diameter and the coefficient of sensitivity of endothelium to shear stress relative to the comparison group was selected only from persons with experience more than 10 years. The comparative analysis of the results of the evaluation of the functional activity of the endothelium in workers of the compared groups indicates that the change in the functional state of the endothelium in miners is associated not only with age, but also with working conditions. The revealed changes predispose to the development of cardiovascular pathology associated with atherosclerosis in workers of underground chrome ore mining.

Working conditions of employees of energy enterprises from the position of non-carcinogenic risks

2020 ◽  
pp. 606-606
Author(s):  
O. V. Grebeneva ◽  
A. Z. Shadetova ◽  
M. V. Rusyaev
Keyword(s):  
Nitrogen Dioxide ◽  
Working Conditions ◽  
Respiratory Diseases ◽  
Combined Effects ◽  
Motor Transport ◽  
Dust Aerosols ◽  
Mineral Oils ◽  
Target Organs ◽  
Power Enterprise

The coefficients of danger to health of 84 workers of 4 lowering stations of the power enterprise from inhalation influence of pollutants of motor transport are calculated: nitrogen dioxide, dust, aerosols of mineral oils and hydrocarbons. The risk of combined effects of chemicals on the target organs was determined by an increase in the chance of respiratory diseases by 1.77 times.

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