Antimicrobial activities of various fractions of longan (Dimocarpus longan Lour.Fen Ke) seed extract

2014 ◽  
Vol 65 (5) ◽  
pp. 589-593 ◽  
Author(s):  
Huang-Chung Tseng ◽  
Wan-Ting Wu ◽  
Ho-Shin Huang ◽  
Ming-Chang Wu
Keyword(s):  
Antimicrobial Activities ◽  
Seed Extract ◽  
Dimocarpus Longan

scholarly journals Free Radical Scavenging, Antimicrobial Activities and Effect of Sub-Acute Exposure to Nigerian Xylopia aethiopica Seed Extract on Liver and Kidney Functional Indices of Albino Rat

2018 ◽  
Vol 12 (3) ◽  
pp. 51-58
Author(s):  
Abubakar Awwal Yusuf ◽  
◽  
Bashir Lawal ◽  
Mumeen Abdulganeey Yusuf ◽  
Mumeen Abdulganeey Yusuf ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Antimicrobial Activities ◽  
Seed Extract ◽  
Diffusion Method ◽  
Total Phenolic ◽  
Frap Assay ◽  
Albino Rat ◽  
Liver And Kidney ◽  
Xylopia Aethiopica

Background: Xylopia aethiopica is highly reputed for its numerous medicinal properties. In the present study, antioxidant, antimicrobial, and toxicity profile of methanol seed extract of Nigerian X. aethiopica in rat were evaluated. Methods: Phytochemical compositions were evaluated using standard procedures. The antibacterial study was carried out using agar well diffusion method, while antioxidant activities were evaluated by DPPH and FRAP assay. Twenty-five rats (5 each) were given 0, 75, 150, 300 and 600 mg/kg bwt of the extract orally for 28 days. Results: The extract had total phenolic and total flavonoid contents of 15.98±0.03mg GAE/g and 2.29±0.02 mg/g CE respectively. The extract had IC50 values of 52.45±3.05 µg/mL and 73.45±3.89 μg/mL in DPPH and FRAP assay respectively. The E. coli showed the highest susceptibility (20.27±0.90mm) while P. aeuruginisa showed the least (15.08±0.20mm). The MIC ranged from 25-50 µg/mL while MBC ranged between 50µg/mL and 100 µg/mL. In comparison with the control rats, the levels of serum creatinine, bicarbonate total proteins, albumin, and ALP were significantly higher in rat dosed 600 mg/kg bwt while urea decreases in rat dose 300 and 600 mg/kg. However, serum concentration of ALT, AST, bilirubin, Na+, K+ and Cl- compared favorably (P>0.05) with control at all doses. Conclusion: The study revealed the antioxidant and antimicrobial activities of Nigerian X. aethiopica, the extract at 75, 150 and 300 mg/kg/b.wt did not provoke toxic effects to the animals’ liver and kidney; however, caution should be exercised when using as a prolonged oral remedy at high doses.

scholarly journals Evaluation of Antimicrobial Activities of Crude Methanol Extract of Phoenix dactylifera Seeds on Clinical Isolates of Different Strains of E. coli

2019 ◽  
pp. 1-7
Author(s):  
C. Eze Chinelo ◽  
N. Ezeibe Ezinwanne ◽  
A. Ozioko Chizoba ◽  
C. Agbo Martina ◽  
N. Ugwu Chineye ◽  
...  
Keyword(s):  
Methanol Extract ◽  
Phoenix Dactylifera ◽  
Antimicrobial Activities ◽  
Seed Extract ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
E Coli ◽  
Agar Diffusion ◽  
Agar Diffusion Method ◽  
Crude Methanol Extract

Aim: This study was conducted to evaluate the antimicrobial activities of seed extract of Phoenix dactylifera. Study Design: Extraction of active ingredients of Phoenix dactylifera seeds using methanol and its effects on selected clinical isolates and isolated strains of E. coli. Place and Duration of Study: `Department of Phatrmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical, University of Nigeria, Nsukka between march 2017 and October 2018. Methodology: The seed of phoenix dactylifera were washed thoroughly to get rid of any adhering date flesh, air dried and ground. The ground powders were subjected to extraction by cold maceration using methanol. Preliminary sensitivity test was carried out against eight microorganisms, namely: Pseudomonas aeruginosa, E. coli, Enterococcus, Klebsiella, Staph. spp, Salmonella spp, Bacillus sp and Candida albicans using agar diffusion method. Antimicrobial susceptibility tests were carried out on isolated strains of E. coli from urine samples using agar diffusion method. The minimal inhibitory concentrations of crude methanol extract of seeds of Phoenix dactylifera were determined using agar diffusion method. The phytochemical analysis was conducted to determine the secondary metabolites. Results: The preliminary sensitivity test performed shows that the crude methanol extract of date seed were sensitive against all organisms tested. The active ingredients of the extract showed activities against all strains of E. coli tested though their zones of inhibition vary (18-21mm). The minimum inhibitory concentration (MIC) value ranges from 10-19.9 mg/ml. The phytochemical analysis of crude methanol seed extract of P. dacterifera indicated the presence of alkaloids, flavonoids, tannins, carbohydrates, proteins, reducing sugar, sterols and Terpenes, Anthraquinone glycosides. Conclusion: The present study provides the scientific information about Phoenix dactylifera seed activity.

scholarly journals Use of Plant Proteins as Microencapsulating Agents of Bioactive Compounds Extracted from Annatto Seeds (Bixa orellana L.)

Antioxidants ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 310 ◽  
Author(s):  
Julián Quintero Quiroz ◽  
Víctor Velazquez ◽  
Ligia Luz Corrales-Garcia ◽  
Juan D. Torres ◽  
Efren Delgado ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Amino Acid Content ◽  
Sodium Caseinate ◽  
Antimicrobial Activities ◽  
Seed Extract ◽  
Ionic Gelation ◽  
Infrared Transmission ◽  
Polyphenol Compounds ◽  
Different Temperatures ◽  
Relevant Factors

This study aimed to assess the thermal stability of the bioactive compounds from annatto seed extract, encapsulated by ionic gelation using quinoa proteins, lentil proteins, soy proteins, and sodium caseinate as carrying materials. The 10.0% aqueous dispersions of the different proteins (carriers) were prepared and mixed with the annatto seed extract. The dispersions were then extruded into a calcium chloride solution to induce the extract encapsulation. The capsules were characterized by encapsulation efficiency, particle size, infrared transmission spectroscopy, confocal microscopy, and scanning electron microscopy (SEM). The antioxidant and antimicrobial activities, the polyphenol compounds, and bixin content from the free and encapsulated extract were assessed once stored for 12 d at different temperatures (4 °C, 25 °C, and 65 °C). The results demonstrated the ability of the proteins to encapsulate the annatto extract with encapsulation efficiencies ranging from 58% to 80%, where the protein structure and amino acid content were the relevant factors to obtain high encapsulation efficiencies. The free extracts stored at 65 °C for 12 d experienced a degradation of bixin and polyphenol compounds, respectively. Conversely, the encapsulated extract had degradations from ~34.00% to ~4.05% for polyphenol compounds and ~20.0% for bixin, respectively. These proteins have a potential encapsulation capacity of annatto extract by ionic gelation.

scholarly journals Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing process

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Preaploy Hong-in ◽  
Waranya Neimkhum ◽  
Chanun Punyoyai ◽  
Suwannee Sriyab ◽  
Wantida Chaiyana
Keyword(s):  
Inflammatory Cytokine ◽  
Biological Activities ◽  
Radical Scavenging ◽  
Thermal Ageing ◽  
Seed Extract ◽  
Cytokine Secretion ◽  
Ageing Process ◽  
Enzyme Linked Immunosorbent Assay ◽  
Chemical Compositions ◽  
Dimocarpus Longan

AbstractThis study is the first to compare the chemical compositions and biological activities of a conventional dried Dimocarpus longan with a novel black D. longan that underwent a thermal ageing process. Pericarp, aril, and seed of both D. longan were macerated in 95% v/v ethanol. Their chemical compositions were investigated using a Folin–Ciocalteu assay, aluminum chloride assay, and high-performance liquid chromatography. Antioxidant activities were evaluated in terms of radical scavenging and iron (III) reduction capacity. An enzyme inhibition assay was used to evaluate the hyaluronidase inhibition. Inflammatory cytokine secretion was evaluated with an enzyme-linked immunosorbent assay. After being exposed to a heating and ageing procedure, gallic acid and ellagic acid content were increased tenfold, while the corilagin content was doubled. Black D. longan seed extract was the most potent anti-hyaluronidase and antioxidant with the strongest free radical scavenging and reduction power, while black D. longan aril extract resulted in the highest inhibition of inflammatory cytokine secretion. Black D. longan contained more biologically active compounds and possessed more potent biological activities than conventional dried D. longan. Therefore, thermal ageing treatment is suggested for producing black D. longan, for which seed extract is suggested as a cosmeceutical active ingredient and aril extract for anti-inflammation.

scholarly journals Evaluation of Wound Healing Potential of Chrysophyllum albidum Hexane Seed Extract in Wistar Rat

2019 ◽  
Vol 2 (1) ◽  
pp. 82-90
Author(s):  
R D Oladeji ◽  
O Babatunde ◽  
I A Ajayi
Keyword(s):  
Wound Healing ◽  
Wistar Rats ◽  
Test Group ◽  
Antimicrobial Activities ◽  
Negative Control ◽  
Seed Extract ◽  
Wound Contraction ◽  
Contraction Rate ◽  
Wound Healing Activity ◽  
Antioxidant And Antimicrobial Activities

Phytochemical, antioxidant and antimicrobial activities of the seeds of Chrysophyllum albidum have been established. However, scientific evaluation of its wound healing activity is lacking. Thus, this study was aimed at evaluating the wound healing potential of Chrysophyllum albidum hexane seed extract using wistar rats. The seed cotyledon was collected, air-dried, blended and extracted with n-hexane by continuous cold extraction. Phytochemicals, antioxidant and antimicrobial activities of the extracts were assayed by standard methods. Three groups of male wistar rats consisting of seven animals each were used for the animal studies. Wound excision was induced on all animals in the sterilized shaved dorsal fur region.Group1 served as the negative control (untreated), groups 2 and 3 were treated with n-hexane extract (test group) and Povidone-iodine ointment (positive control) respectively. Wound contraction rate and epithelialization time were used to assess the efficiency of the treatment. Group 3 rats had best wound contraction rate with epithelialization time of 16 post-wounding day followed by group 2 (20 days) and group 1 (28 days). The wound healing efficiency of the extract was less than that of the standard ointment but it healed the wound inflicted on the rats faster than the untreated ones. The low wound activity of the seed extract may be due to low phytochemical, antioxidant and antimicrobial activity of the extract. Chrysophyllum albidum hexane seed extract have some wound healing activity and therefore have potential for being used as wound healing ointment.

Antioxidant Activity of Longan (Dimocarpus Longan L.) Seed Extract

2011 ◽  
pp. 705-710
Author(s):  
Kai Wang ◽  
Ying Liang ◽  
Ye Zhang ◽  
Xianghui Yi ◽  
Hengshan Wang ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Seed Extract ◽  
Dimocarpus Longan

scholarly journals Antimicrobial Activity of Terpenoids Extracted from Annona muricata Seeds and its Endophytic Aspergillus niger Strain SH3 Either Singly or in Combination

2019 ◽  
Vol 7 (19) ◽  
pp. 3127-3131 ◽  
Author(s):  
Tahany Abdel-Rahman ◽  
Amal-Saad Hussein ◽  
Safia Beshir ◽  
Ahmed R. Hamed ◽  
Eman Ali ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Aspergillus Niger ◽  
Antimicrobial Activities ◽  
Fungal Species ◽  
Antagonistic Effect ◽  
Seed Extract ◽  
Annona Muricata ◽  
E Coli ◽  
Brown Colour ◽  
Antimicrobial Assay

BACKGROUND: Annona muricata (Soursop) has an antimicrobial activity toward various pathogenic microorganisms which support its ethnomedicinal for the treatment of many infectious diseases. AIM: Aim of the present study to evaluate the relation between antimicrobial activities of terpenoids extracted from different soursop parts with the isolated endophytic fungi. METHODS: Endophytic fungal species of pulp and peel of Annona fruit along with those of seeds were isolated. Salkowski test was used for qualitative screening of terpenoids in plant and the isolated endophytic Aspergillus niger strain SH3. RESULTS: Endophytic A. niger strain SH3 and Annona seed extract showed high terpenoid content indicated by the high intensity of reddish-brown colour. GC/Mass analysis revealed six compounds of terpenoids from endophytic A. niger strain SH3 extract and four compounds from seed extract with different retention times. The antimicrobial assay was performed using A. niger strain SH3 extract and Annona seed extract singly or in combinations against S. aureus, P. aeruginosa, E. coli and C. albicans. CONCLUSION: The results revealed the significant antimicrobial activity of both extracts. However, the combined extract showed some reduction in antimicrobial activity which could be attributed to the antagonistic effect exhibited by their constituents.

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