Dermatophytes: role of host genetics in the development of illness

2021 ◽  
Author(s):  
Moataz Dowaidar

Because dermatophytes and their hosts are so different, infection susceptibility is most likely the consequence of changes on both sides, as well as reciprocal adaptation. In addition, some studies have revealed a role for host genetics in the development of illness, including possible Mendelian inheritance patterns for dermatophytosis tendency. This paper emphasizes the complexity of the genetic link between dermatophytes and their natural and accidental hosts. According to a literature study, different ideas and methodologies may lead to different interpretations of this connection. Selecting an appropriate model for analysis and reasoning is a critical step in better understanding these disorders. A significant portion of the research is focused on the host's genetic and immunological response to dermatophyte infection. Future studies will require a broader exploration of the dermatophyte genome in combination with analysis of large phenotypically well-characterized populations of various dermatophyte species in order to identify the main factors mediating infection risk that can be targeted to disrupt host–pathogen interactions and used in therapies. As a result, both conceptually and practically, extensive study on the interactions between dermatophytes and their specific hosts, which comprise intricate molecular pathways, is critical. However, it is undeniable that genetic predisposition plays a crucial role in the susceptibility to dermatophyte infection.

2020 ◽  
Vol 48 (2) ◽  
pp. 429-439 ◽  
Author(s):  
Jorge Gago ◽  
Danilo M. Daloso ◽  
Marc Carriquí ◽  
Miquel Nadal ◽  
Melanie Morales ◽  
...  

Besides stomata, the photosynthetic CO2 pathway also involves the transport of CO2 from the sub-stomatal air spaces inside to the carboxylation sites in the chloroplast stroma, where Rubisco is located. This pathway is far to be a simple and direct way, formed by series of consecutive barriers that the CO2 should cross to be finally assimilated in photosynthesis, known as the mesophyll conductance (gm). Therefore, the gm reflects the pathway through different air, water and biophysical barriers within the leaf tissues and cell structures. Currently, it is known that gm can impose the same level of limitation (or even higher depending of the conditions) to photosynthesis than the wider known stomata or biochemistry. In this mini-review, we are focused on each of the gm determinants to summarize the current knowledge on the mechanisms driving gm from anatomical to metabolic and biochemical perspectives. Special attention deserve the latest studies demonstrating the importance of the molecular mechanisms driving anatomical traits as cell wall and the chloroplast surface exposed to the mesophyll airspaces (Sc/S) that significantly constrain gm. However, even considering these recent discoveries, still is poorly understood the mechanisms about signaling pathways linking the environment a/biotic stressors with gm responses. Thus, considering the main role of gm as a major driver of the CO2 availability at the carboxylation sites, future studies into these aspects will help us to understand photosynthesis responses in a global change framework.


2018 ◽  
Vol 77 (3) ◽  
pp. 127-131
Author(s):  
Gérald Delelis ◽  
Véronique Christophe

Abstract. After experiencing an emotional event, people either seek out others’ presence (social affiliation) or avoid others’ presence (social isolation). The determinants and effects of social affiliation are now well-known, but social psychologists have not yet thoroughly studied social isolation. This study aims to ascertain which motives and corresponding regulation strategies participants report for social isolation following negative emotional events. A group of 96 participants retrieved from memory an actual negative event that led them to temporarily socially isolate themselves and freely listed up to 10 motives for social isolation. Through semantic categorization of the 423 motives reported by the participants, we found that “cognitive clarification” and “keeping one’s distance” – that is, the need for cognitive regulation and the refusal of socioaffective regulation, respectively – were the most commonly and quickly reported motives for social isolation. We discuss the findings in terms of ideas for future studies aimed at clarifying the role of social isolation in health situations.


Author(s):  
Marsel Eliaser Liunokas

Timorese culture is patriarchal in that men are more dominant than women. As if women were not considered in traditional rituals so that an understanding was built that valued women lower than men. However, in contrast to the article to be studied, this would like to see the priority of women’s roles in traditional marriages in Belle village, South Central Timor. The role of women wiil be seen from giving awards to their parents called puah mnasi manu mnasi. This paper aims to look at the meaning of the rituals of puah mnasi maun mnasi and the role and strengths that women have in traditional marriage rituals in the village of Belle, South Central Timor. The method used for this research is a qualitative research method using interview techniques with a number of people in the Belle Villa community and literature study to strengthen this writing. Based on the data obtained this paper shows that the adat rituals of puah mnasi manu mnasi provide a value that can be learned, namely respect for women, togetherness between the two families, and brotherhood that is intertwined due to customary marital affrairs.


KUTTAB ◽  
2017 ◽  
Vol 1 (1) ◽  
pp. 50-57
Author(s):  
Salman Zahidi

Ali Bin Abi Talib once said that children should be educated in accordance with the  development of the times. The Ali bin Abi Talib’s statement could be considered as his attention more to the development of human civilization. For that reason, there should be studies focused on the role of educational institutions in facing the challenges of the times. On this stand, the writer raises the existence of pesantren (Islamic boarding schools) for being considered to have been able to survive amid the onslaught of civilization increasingly obscuring cultural identity. In addition, this study also aims to identify and discuss the role of pesantren in the modern era. This is a literature study using a descriptive and exploratory approach. It can be concluded that pesantren are non-formal Islamic educational institutions. Pesantren have permanent and distictive methods and learning models. The purpose of pesantren education is the same as Islamic education in general, instilling a sense of virtue, familiarizing themselves with courtesy, preparing for a holy, sincere and honest life entirely. Pesantren could be seen from three aspects: (a) pesantren that are seen from facilities and infrastructures, (b) pesantren that are seen from disciplines taught, and (c) pesantren that are seen from the fields of knowledge.


2020 ◽  
Author(s):  
Maihilza Wiwi Fauziah

Specialized service management is a process of providing service needs to students to support learning activities so that educational goals can be achieved effectively and efficiently. The services provided by the school are very satisfying, such as a library that is equipped with books that fit the lesson, labor that makes students feel happy to experiment, the school health unit (UKS) is a health business run at a school that makes students majoring in science especially feel comfortable and at ease, school cafeteria, religious advice, boarding, cooperatives and transportation. The researcher uses the literature study method by collecting literature study methods by collecting material materials both sourced from books, journals, and other sources related to the administration of facilities and infrastructure. Related sources are about understanding special service administration, types of special services, and also the role of the teacher in the administration of special services. Research uses the literature study method by collecting literature study methods by collecting material materials both sourced from books, journals, and other sources related to the administration of facilities and infrastructure. Related sources are about understanding special service administration, types of special services, and also the role of the teacher in the administration of special services.


2020 ◽  
Author(s):  
nurul atika

Abstrak- In general, this study aims to determine and analyze the role of supervision in an education. This research uses the literature study method by collecting literature (material materials) sourced from books, journals, and other sources related to the science of Educational Administration. Supervision comes from the word super and vision, which means to see and review from above or view and assess from above, which is carried out by superiors on the activities, creativity and performance of subordinates. In terms of terms, in Carter's Good Dictionary Education, supervision is all the efforts of school officials in leading teachers and other education personnel to improve teaching. These include stimulating, selecting the growth and development of teachers' positions, selecting and revising educational goals, teaching materials and teaching methods, and evaluating teaching. Educational supervision has very important goals and benefits. The scope of educational supervision includes the following: Managerial supervision of the curriculum, Managerial supervision of student affairs, Managerial supervision of educators and education personnel, Managerial supervision of facilities and infrastructure, Managerial supervision of finance, Managerial supervision of public relations, Managerial supervision of administration, Administration supervision academics about learning, related to methods, sourcing strategies, and evaluations.


2020 ◽  
Vol 3 (1) ◽  
pp. 20-31
Author(s):  
Novana Veronica Julenta Kareth ◽  
Reni Shintasari

This paper aims to determine the policies implemented by the Papua National Narcotics Agency against drug trafficking. This article is a qualitative descriptive study. Data collection methods through interviews and literature study. Data analysis using descriptive analysis model. The results showed that the role of BNN Papua is very central in the eastern region and the Indonesian border. The policies that have been planned by BNN with multi-stakeholder have been implemented, but the new modes adopted by the international network vary. The drug subscription policy cannot be carried out by one institution only, it needs to be supported by other government agencies and the community. The need for a serious role for the regional and central government in both preventive efforts and subscription programs in synergy with the Papua Provincial BNN.


Urban Science ◽  
2020 ◽  
Vol 4 (4) ◽  
pp. 70
Author(s):  
Till Koglin ◽  
Lucas Glasare

This paper evaluates the history and cycling accessibility of Nova, a shopping centre established in Lund, Sweden, in 2002. The current situation was also analysed through observation and a literature review. Moreover, the study conducted a closer analysis of the history and role of the municipality based on further literature study and interviews with officials. The conclusion of the analysis indicates poor and unsafe bikeways caused by conflicts of interest between politicians, officials, landowners and the general public. It also depicts a situation in which the municipality’s master plan has been ignored, and, in contrast to the local goals, cycling accessibility at Nova has seen no significant improvement since the shopping centre was first established. The reasons for this, arguably, are a relatively low budget for bikeway improvements in the municipality, as well as a situation in which decision-makers have stopped approaching the subject, as a result of the long and often boisterous conflicts it has created in the past. Lastly, it must be noted that it is easy to regard the whole process of Nova, from its establishment to the current situation, as being symptomatic of the power structures between drivers and cyclists that still affect decision-makers at all levels.


2017 ◽  
Vol 11 (9) ◽  
pp. 721-737 ◽  
Author(s):  
Craig Kinnear ◽  
Eileen G. Hoal ◽  
Haiko Schurz ◽  
Paul D. van Helden ◽  
Marlo Möller
Keyword(s):  

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