Suicidal Ideation and Risk Reduction Associated with Participation in an Evidence-Based mHealth Intervention
Introduction: Suicide is a significant public health concern with increasing prevalence. Novel interventions that reduce stigma and increase accessibility, such as mobile health (mHealth) interventions, are urgently needed. Methods: This retrospective cohort intent-to-treat study examined suicidal ideation (SI) trajectories using multilevel models during and up to 6-months after an evidence-based 12-week mHealth intervention (Meru Health Program [MHP]) as assessed by the ninth item of the Patient Health Questionnaire-9 (PHQ-9). Estimates of associated suicide attempts and deaths by suicide were calculated using published data linking PHQ-9-assessed SI to records of suicide attempts and deaths by suicide. Results: MHP participants reporting SI “not at all” significantly increased between baseline and end-of-treatment (78.02% to 91.00%). Effect sizes of SI changes between baseline and end-of-treatment, 3-month, and 6-month follow-ups were 0.33 (95%CI=0.27-0.38), 0.32 (95%CI=0.27-0.38), and 0.32 (95%CI=0.27-0.438), respectively. Results also indicated an estimated 30.49% reduction (95%CI=25.15%-35.13%) in suicide attempts and death by suicide across treatment.Conclusion: This real-world study indicates that participants of the MHP show significant reductions in SI and estimated suicide attempts and deaths by suicide across treatment that are maintained 6-months following treatment.