scholarly journals Assessing the organizational climate for translational research with a new survey tool

2019 ◽  
Author(s):  
Arno Simons ◽  
Nico Riedel ◽  
Ulf Toelch ◽  
Barbara Hendriks ◽  
Stephanie Ohlraun ◽  
...  
Keyword(s):  
Organizational Climate ◽  
Translational Research ◽  
Assessment Tool ◽  
University Hospital ◽  
Practical Implementation ◽  
Contributing Factors ◽  
Research Practices ◽  
Survey Tool ◽  
Research Climate ◽  
The Impact

Promoting biomedical translation from bench to bedside and back in organizational settings is a central challenge for research managers and policymakers. For this, organizational leaders need to assess baseline conditions, identify areas needing improvement, and to judge the impact of specific initiatives to sustain or improve translational research practices at their institutions. Currently, there is a lack of such an assessment tool addressing the specific context of translational biomedical research. To close this gap, we have developed and tested a new survey for assessing the organizational climate for translational research. This self-assessment tool measures employees’ perceptions of translational climate and underlying research practices in organizational environments and builds on the established Survey of Organizational Research Climate. Having implemented the new survey in practice, we show that scientists at a large university hospital (Charité Berlin) perceive translation as a central and important component of their work. Importantly, local resources and direct support are main contributing factors for the practical implementation of translation into their own research practice. We identify and discuss potential leverage points for an improvement of research climate to foster successful translational research.

scholarly journals Assessing the Organizational Climate for Translational Research with a New Survey Tool

2020 ◽  
Vol 26 (6) ◽  
pp. 2893-2910 ◽  
Author(s):  
Arno Simons ◽  
Nico Riedel ◽  
Ulf Toelch ◽  
Barbara Hendriks ◽  
Stephanie Müller-Ohlraun ◽  
...  
Keyword(s):  
Organizational Climate ◽  
Translational Research ◽  
Assessment Tool ◽  
Research Integrity ◽  
University Hospital ◽  
Practical Implementation ◽  
Research Practices ◽  
Survey Tool ◽  
Research Climate ◽  
The Impact

AbstractPromoting translational research as a means to overcoming chasms in the translation of knowledge through successive fields of research from basic science to public health impacts and back is a central challenge for research managers and policymakers. Organizational leaders need to assess baseline conditions, identify areas needing improvement, and to judge the impact of specific initiatives to sustain or improve translational research practices at their institutions. Currently, there is a lack of such an assessment tool addressing the specific context of translational biomedical research. To close this gap, we have developed a new survey for assessing the organizational climate for translational research. This self-assessment tool measures employees’ perceptions of translational research climate and underlying research practices in organizational environments and builds on the established Survey of Organizational Research Climate, assessing research integrity. Using this tool, we show that scientists at a large university hospital (Charité Berlin) perceive translation as a central and important component of their work. Importantly, local resources and direct support are main contributing factors for the practical implementation of translation into their own research practice. We identify and discuss potential leverage points for an improvement of research climate to foster successful translational research.

scholarly journals EFFECT OF PREOPERATIVE PREPARATION ON PATIENTS OUTCOME AMONG PATIENTS UNDERGOING SURGICAL OPERATIONS AT ALMIK NIMIR HOSPITAL – SUDAN

2020 ◽  
Vol 8 (8) ◽  
pp. 346-355
Author(s):  
Eied Saber Al amine Ali ◽  
Higazi Mohammed Ahmed Abdallah
Keyword(s):  
Assessment Tool ◽  
Elective Surgery ◽  
Computer Software ◽  
University Hospital ◽  
Care Plan ◽  
Postoperative Phase ◽  
Preoperative Preparation ◽  
Quasi Experimental ◽  
Two Phases ◽  
The Impact

Preoperative preparations of the patients physically and psychologically are the cornerstone of the good outcomes. This prospective quasi-experimental hospital-based study was conducted in Sudan, Shendi city at Elmek Nimer university hospital to evaluate the impact of preoperative preparation on patients outcome among patients undergoing general surgery. In the period of June 2016 to May 2019. The study was included a hundred patients undergoing general elective surgery, data were collected by interviewing questionnaire, anxiety scale, pain assessment tool, postoperative parameter, and patients satisfaction tool, data were collected in two phases (pre& postoperative). The data were analyzed by the computer software program (SPPS) version 20. The results showed that more than two third (79.4%) of the patient had poor knowledge about the importance of preoperative preparations, but improve after implemented program and this was reflected on patient behavior and outcome in the postoperative phase. (70%) had reported no anxiety to mild in the postoperative phase. in regard of postoperative pain, majority of patients (70%) experienced moderate to severe level of pain in the first 4 hours, this level of pain reduce to mild to no pain level in (82%) of patients in next 12hours. Most of the patients had full to good satisfaction regarding preparations and outcome. The study support and justifies the effectiveness of the preoperative preparations on patient outcomes. The study recommended surgical nurses have to provide proper explanation and teaching for elective surgical patients to be adherence with the care plan to promote good surgical outcome.

scholarly journals A pre/post analysis of the impact of the COVID-19 pandemic on the psychosocial work environment and recovery among healthcare workers in a large university hospital in Sweden

2021 ◽  
Author(s):  
Ingibjörg H. Jonsdottir ◽  
Alessio Degl’Innocenti ◽  
Linda Åhlström ◽  
Caterina Finizia ◽  
Helle Wijk ◽  
...  
Keyword(s):  
Work Environment ◽  
Working Conditions ◽  
Healthcare Workers ◽  
Well Being ◽  
Working Environment ◽  
University Hospital ◽  
Contributing Factors ◽  
Employee Survey ◽  
Hospital Employees ◽  
The Impact

Background. The impact of the COVID-19 pandemic on workload, mental health, and well-being of healthcare workers, and particularly those on the front-line, has received considerable attention.Design and methods. We surveyed hospital employees about their working environment during the pandemic and identified departments which were negatively affected in comparison to the pre-pandemic situation, as well as factors contributing to this.Setting and participants We surveyed all hospital employees at Sahlgrenska University Hospital, Sweden in September 2020 and compared results across departments and to the results of a large employee survey from October 2019.Results. The overall impact of the pandemic on perceived working conditions and possibility for recovery differed among departments. During the pandemic, healthcare workers working with COVID-19 patients reported poorer working environments than other employees. Factors significantly related to perception of work environment and recovery during the pandemic included worries of being infected, departmental transfer, and having insufficient access to personal protective equipment. Men reported better working conditions than women in all, but one item and higher age was related to better perceived working environment.Conclusions. Our results indicate that the pandemic differentially affects hospital departments and underscores the multifactorial nature of this topic. Contributing factors to poor perceived working environment could be addressed at times of high workload, such as during the pandemic, including providing appropriate support to managers, ensuring possibility for recovery during working hours, and acknowledging worries about infection. Young healthcare workers and staff who are relocated due to the pandemic warrant special attention.

scholarly journals The development and validation of a resource consumption score of an emergency department consultation

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0247244
Author(s):  
Martin Müller ◽  
Clyde B. Schechter ◽  
Wolf E. Hautz ◽  
Thomas C. Sauter ◽  
Aristomenis K. Exadaktylos ◽  
...  
Keyword(s):  
Emergency Department ◽  
External Validation ◽  
Chief Complaint ◽  
Resource Consumption ◽  
University Hospital ◽  
Contributing Factors ◽  
Night Time ◽  
Final Model ◽  
Ed Visits ◽  
The Impact

Background Emergency Department (ED) visits and health care costs are increasing globally, but little is known about contributing factors of ED resource consumption. This study aims to analyse and to predict the total ED resource consumption out of the patient and consultation characteristics in order to execute performance analysis and evaluate quality improvements. Methods Characteristics of ED visits of a large Swiss university hospital were summarized according to acute patient condition factors (e.g. chief complaint, resuscitation bay use, vital parameter deviations), chronic patient conditions (e.g. age, comorbidities, drug intake), and contextual factors (e.g. night-time admission). Univariable and multivariable linear regression analyses were conducted with the total ED resource consumption as the dependent variable. Results In total, 164,729 visits were included in the analysis. Physician resources accounted for the largest proportion (54.8%), followed by radiology (19.2%), and laboratory work-up (16.2%). In the multivariable final model, chief complaint had the highest impact on the total ED resource consumption, followed by resuscitation bay use and admission by ambulance. The impact of age group was small. The multivariable final model was validated (R2 of 0.54) and a scoring system was derived out of the predictors. Conclusions More than half of the variation in total ED resource consumption can be predicted by our suggested model in the internal validation, but further studies are needed for external validation. The score developed can be used to calculate benchmarks of an ED and provides leaders in emergency care with a tool that allows them to evaluate resource decisions and to estimate effects of organizational changes.

scholarly journals Chronic Histiocytic Intervillositis: A Placental Histopathologic Feature in Vertical Transmission of Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S147-S148
Author(s):  
J Oentoro ◽  
S Jalali-Farahani ◽  
J Davis ◽  
S Zee
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Vertical Transmission ◽  
Large Scale ◽  
University Hospital ◽  
Control Group ◽  
Contributing Factors ◽  
Chi Square ◽  
The Impact ◽  
Histopathologic Feature ◽  
Histopathologic Features

Abstract Introduction/Objective Vertical transmission of severe acute respiratory syndrome associated with coronavirus-2 (SARS-CoV-2) infection has been reported as a rare occurrence. The purpose of this study is to identify any specific placental histopathologic abnormalities associated with SARS-CoV-2 infection, compare differences between mothers with symptomatic and asymptomatic coronavirus disease 2019 (COVID-19), and determine the frequency of vertical transmission. Methods/Case Report Placentas from mothers diagnosed with COVID-19 during pregnancy and delivered at Stony Brook University Hospital were identified. A control group of mothers with a negative COVID-19 test was selected from the same period. The frequency of histopathologic characteristics defined by the Amsterdam Placental Workshop Group Consensus was compared using chi-square tests between the following cohorts: COVID-19 positive mothers against COVID-19 negative mothers and symptomatic COVID-19 mothers against asymptomatic COVID-19 positive mothers. Results (if a Case Study enter NA) A retrospective study reviewed 23 placentas from mothers with COVID-19 for features of maternal vascular malperfusion, fetal vascular malperfusion, and inflammatory changes. 11 mothers displayed symptomatic COVID-19, and 12 mothers were asymptomatic. One neonate tested positive for SARS-CoV-2. No significant differences were identified in the frequency of the examined placental histopathologic characteristics between COVID-19 positive and negative mothers. The degree of COVID-19 severity did not significantly impact the frequency of examined histopathologic features. Interestingly, in the case with vertical transmission, the placenta demonstrated the only finding of chronic histiocytic intervillositis (CHI) with associated trophoblast necrosis. Conclusion Comparing across groups based on COVID-19 status, this study found no specific placental histopathologic features associated with maternal SARS-CoV-2 infection, regardless of symptom severity. However, in one case of vertical transmission, CHI was a unique histopathologic feature. These findings are consistent with the current literature. Further large-scale investigations are needed to establish additional patterns of specific placental histopathology, incidence and contributing factors of vertical transmission of COVID-19, and the impact of CHI in future pregnancies of affected women.

Efficacy of Crisis Intervention

Crisis ◽  
1999 ◽  
Vol 20 (2) ◽  
pp. 78-85 ◽  
Author(s):  
Thomas Reisch ◽  
Petra Schlatter ◽  
Wolfgang Tschacher
Keyword(s):  
Crisis Intervention ◽  
Intervention Program ◽  
Suicide Ideation ◽  
Indirect Evidence ◽  
Well Being ◽  
Term Therapy ◽  
Contributing Factors ◽  
Step Therapy ◽  
Long Term Therapy ◽  
The Impact

This study assesses the efficacy of the treatment approach implemented in the Bern Crisis Intervention Program, where particular emphasis is placed on the remediation of suicide ideation and suicidal behavior, and depression, fear, and phobia are generally considered to be contributing factors. Four questionnaires addressing psychopathology, emotional well-being, social anxiety, and personality were administered prior to and after the treatment of 51 patients over a period of 2 to 3 weeks. The reduction of symptoms contributing to suicidal ideation and behavior was interpreted as indirect evidence of an antisuicidal effect of the program. Significant improvements were found in the psychopathology ratings, with depression and anxiety showing the largest reductions. The impact on personality and social phobia, however, was only moderate, and on average patients still exhibited symptoms after attending the program. This residual symptomatology points to the necessity of introducing a two-step therapy approach of intensive intervention targeted at the precipitating causes of the crisis, augmented by long-term therapy to treat underlying problems.

Antecedents And Outcomes Of Qwl Among Employees In Banks

2019 ◽  
Vol 118 (7) ◽  
pp. 1-19
Author(s):  
Geethanjali N ◽  
Parveen Roja M ◽  
Lavanya D
Keyword(s):  
Organizational Climate ◽  
Job Stress ◽  
Work Life ◽  
Working Environment ◽  
Quality Of Work Life ◽  
Quality Of Work ◽  
Significant Difference ◽  
Service Productivity ◽  
The Impact

Quality of work life is the major factor to be considered in working environment of any organization. The performance of employees and the organization lies on the ability of the employees based on working environment. The QWL leads to better working environment which improves the performance of organization. The present study has made an attempt to find the level of factors causing QWL and the impact of outcome of QWL in banks. Since the profile of the banks may be associated with the level of outcomes of QWL, the present study has made an attempt to examine it with the help of one way analysis of variance and t-test. The included outcomes of QWL are job satisfaction, job stress, organizational climate, organizational commitment, employees retention behaviour, service quality employees and service productivity of employees. The highly associated determinants of QWL and the significant difference among the PUSBs and PRSBs have been noticed. The significantly associating important profiles of the banks regarding the existence of outcome of QWL are identified.

The Impact of Translational Research in Breast Cancer Care: Can we Improve the Therapeutic Scenario?

2018 ◽  
Vol 18 (6) ◽  
pp. 832-836
Author(s):  
Giuseppe Buono ◽  
Francesco Schettini ◽  
Francesco Perri ◽  
Grazia Arpino ◽  
Roberto Bianco ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Translational Research ◽  
Cell Biology ◽  
Cancer Biology ◽  
Hormone Receptors ◽  
Treatment Strategies ◽  
Growth Factor Receptor ◽  
Molecular Heterogeneity ◽  
Therapeutic Implications ◽  
The Impact

Traditionally, breast cancer (BC) is divided into different subtypes defined by immunohistochemistry (IHC) according to the expression of hormone receptors and overexpression/amplification of human epidermal growth factor receptor 2 (HER2), with crucial therapeutic implications. In the last few years, the definition of different BC molecular subgroups within the IHC-defined subtypes and the identification of the important role that molecular heterogeneity can play in tumor progression and treatment resistance have inspired the search for personalized therapeutic approaches. In this scenario, translational research represents a key strategy to apply knowledge from cancer biology to the clinical setting, through the study of all the tumors “omics”, including genomics, transcriptomics, proteomics, epigenomics, and metabolomics. Importantly, the introduction of new high-throughput technologies, such as next generation sequencing (NGS) for the study of cancer genome and transcriptome, greatly amplifies the potential and the applications of translational research in the oncology field. Moreover, the introduction of new experimental approaches, such as liquid biopsy, as well as new-concept clinical trials, such as biomarker-driven adaptive studies, may represent a turning point for BC translational research. </P><P> It is likely that translational research will have in the near future a significant impact on BC care, especially by giving us the possibility to dissect the complexity of tumor cell biology and develop new personalized treatment strategies.

Understanding the Impact of Bullying in a Unionized U.S. Public Sector Workforce

2019 ◽  
Vol 68 (3) ◽  
pp. 139-153 ◽  
Author(s):  
Mazen El Ghaziri ◽  
Shellie Simons ◽  
Jane Lipscomb ◽  
Carla L. Storr ◽  
Kathleen McPhaul ◽  
...  
Keyword(s):  
Public Sector ◽  
Organizational Climate ◽  
Negative Impact ◽  
Multinomial Logistic Regression ◽  
Female Gender ◽  
Bargaining Unit ◽  
Organizational Level ◽  
Organizational Impact ◽  
Cross Sectional ◽  
The Impact

Background: Workplace Bullying (WPB) can have a tremendous, negative impact on the victims and the organization as a whole. The purpose of this study was to examine individual and organizational impact associated with exposure to bullying in a large U.S. unionized public sector workforce. Methods: A cross-sectional Web-based survey was conducted among 16,492 U.S. state government workers. Survey domains included demographics, negative acts (NAs) and bullying, supportiveness of the organizational climate, and individual and organizational impacts of bullying. Multinomial logistic regression was used to assess the impact among respondents who reported exposure to bullying. Findings: A total of 72% participants responded to the survey (n = 11,874), with 43.7% (n = 5,181) reporting exposure to NAs and bullying. A total of 40% (n = 4,711) participants who experienced WPB reported individual impact(s) while 42% ( n = 4,969) reported organization impact(s). Regular NA was associated with high individual impact (negatively impacted them personally; odds ratio [OR] = 5.03) when controlling for other covariates including: female gender (OR =1.89) and job tenure of 6 to 10 years (OR = 1.95); working in a supportive organizational climate and membership in a supportive bargaining unit were protective of high impact (OR = 0.04 and OR = 0.59, respectively). High organizational impact (transferring to another position) was associated with regular NA and bullying (OR = 16.26), female gender (OR = 1.55), providing health care and field service (OR = 1.68), and protective effect of organizational climate (OR = 0.39). We found a dose-response relationship between bullying and both individual and organizational-level impact. Conclusion/Application to Practice: Understanding the impacts of WPB should serve to motivate more workplaces and unions to implement effective interventions to ameliorate the problem by enhancing the organizational climate, as well as management and employee training on the nature of WPB and guidance on reporting.

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