scholarly journals Association of Hypertension and its risk factor in Type II diabetes mellitus patients

2021 ◽  
Vol 12 (1) ◽  
pp. 28-33
Author(s):  
Seema Singh ◽  
Nitin Ranjan Gupta ◽  
Syed Tahseen Raza ◽  
Avadh Kapoor ◽  
Pooja Singh
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Risk Factors ◽  
Blood Pressure ◽  
Type Ii Diabetes ◽  
Diabetic Patients ◽  
Type Ii ◽  
Blood Pressure Monitor ◽  
Pressure Monitor ◽  
Cross Sectional

Background: There are few reports in India about the correlation of hypertension, its risk factors and its relationship with type II diabetes. Several studies have shown that Type II diabetes in India is increasingly widespread. Aims and Objective: The main purpose of this research is to determine the association between hypertension and type II mellitus diabetes. Materials and Methods: The Department of Physiology, Era Medical College & Hospital, Lucknow and the Department of Internal Medicine, Hind Institute of Medical Sciences and Research, Sitapur, performed a cross-sectional study on 520 patients with type II diabetes. The structured questionnaire was prepared to collect history of hypertension, social and demographical parameters and diabetes duration. A trained staff has measured anthropometric data like height, weight and also took blood pressure by digital blood pressure monitor (CITIZEN-CH-432). Results: This study indicated a significant (p<0.001) relationship between BMI and hypertension in diabetes mellitus II patients. This study has also shown significant relationship between physical activity and hypertension in diabetes mellitus patients. The logistic regression study demonstrated that hypertension in diabetes mellitus patients has been positively associated with age (p<10-4) sensitivity level (p<10-3) and period of diabetes (p<10-2). Conclusion: Hypertension is a common issue among diabetic Indians. This research focused primarily on the association of hypertension and its related risk factors in patients with diabetes. The study showed that hypertension in diabetic patients is associated with age, physical activity, awareness level and BMI. More studies on larger sample sizes are needed to validate the current findings.

scholarly journals Evaluation of sweet taste sensitivity in type-II Diabetes Mellitus patients

2020 ◽  
pp. 10-12
Author(s):  
Z. Naveen Kumar ◽  
B.N.S. Gowri Kumari
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Sweet Taste ◽  
Cross Sectional Study ◽  
Taste Sensitivity ◽  
Diabetic Patients ◽  
Type Ii ◽  
Cross Sectional ◽  
The Mean

Background: The objective is to evaluate the sweet taste sensitivity among type-II diabetes mellitus patients. Methods:  This is a cross sectional study consisted of 227 subjects (127 type-II Diabetic patients & 100 non diabetic individuals) of both the genders and age matched. Sweet taste sensitivity tests were done using different concentrations of glucose solution and compared among the diabetic patients with FBS more than 180mg/dl and diabetic patients with FBS less than 180mg/dl and also compared among the diabetic patients and non diabetic individuals.  The final concentration at which patient was able to perceive the taste was recorded. statistical analysis was done using Student’s unpaired T test. P­values of < 0.05 were considered to be statistically significant. Results: The mean of sweet taste sensitivity among diabetic patients with FBS >180 mg/dl was 6245 mg/l and the mean of sweet taste sensitivity in the diabetic patients with FBS <180 mg/dl was 2249mg/l with P<0.001 which is significant. The mean of sweet taste sensitivity among diabetic patients with FBS >180 mg/dl was 6245mg/l and the mean of sweet taste sensitivity in the non diabetic individuals was 1979mg/l with P<0.01 which is significant. the mean of sweet taste sensitivity among diabetic patients with FBS <180 mg/dl was 2249 mg/l and the mean of sweet taste sensitivity in the non diabetic individuals was 1979mg/l  with P>0.05 which is not significant. Conclusion: In our study it was concluded that type-II Diabetes Mellitus patients have lesser sensitivity for the sweet taste. Loss of sensitivity leads to the increase in sugar consumption being the risk factor for worsening the disease.

Beliefs, Benefits and Barriers Associated with Physical Activity: Impact of These Factors on Physical Activity in Patients With Type II Diabetes Mellitus

2020 ◽  
pp. 105477382096769
Author(s):  
Hsiang-Ju Hsu ◽  
Ding-Tien Chung ◽  
Li-Yun Lee ◽  
I-Pei Lin ◽  
Shu-Ching Chen
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Self Efficacy ◽  
Type Ii Diabetes ◽  
Tai Chi ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Patient Centered ◽  
Cross Sectional ◽  
Activity Performance

This study aimed to assess patients’ levels of belief, benefits and barriers toward physical activity, and to identify factors associated with physical activity performance in patients with type II diabetes mellitus (T2DM). The study was carried out using cross-sectional correlation design. Subjects from the endocrinology and metabolism outpatient departments of a teaching hospital in northern Taiwan were recruited by consecutive sampling. A total of 149 patients with type II DM were recruited. More physical activity was associated with stronger physical activity beliefs, including recovery self-efficacy, action and coping planning, and maintenance self-efficacy, which explained 40.9% of variance in physical activity performance. Patient-centered physical activity programs (resistance exercise, daily walking, or Tai Chi exercise) can reduce patients’ barriers toward performing physical activity.

Obesity But not Hypertension Is the Major Determinant of Endothelial Activation in Type II Diabetes.

Hypertension ◽  
2000 ◽  
Vol 36 (suppl_1) ◽  
pp. 724-724
Author(s):  
Geoff D Braatvedt ◽  
Warwick Bagg ◽  
Giovambattista Desideri ◽  
G Gamble ◽  
Paul Ockleford ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Multivariate Analysis ◽  
Metabolic Control ◽  
Type Ii Diabetes ◽  
Endothelial Activation ◽  
Diabetic Patients ◽  
No Production ◽  
Type Ii ◽  
Type Ii Diabetics

P174 In order to evaluate the independent role of hypertension and other risk factors in promoting endothelial activation in type II diabetes, several markers of endothelial damage were studied in 43 type II diabetic patients (24 F,30-65 ys), before and after the random assignment to a 20-week period of either aggressive (AC, n=20) or usual (UC, n=22) metabolic control. Compared to matched controls (n=15) type II diabetic patients showed a significant (p<0.05 or less) elevation of circulating P-selectin, E-selectin, ICAM-1, VCAM-1 and Endothelin-1 (ET-1) levels and a simultaneos decrement of total nitric oxide(NO). Multivariate analysis showed that only BMI not dependently influenced (p=0.01 or less) E-selectin, ICAM-1 and total NO, with a trend for P-selectin levels (p=0.06). Accordingly, basal BMI correlated with ICAM-1 (r=0.45, p=0.003), E-selectin (r=0.41, p=0.007) and P-selectin (r=0.34, p=0.02). In addition, P-selectin and E-selectin resulted higher(p<0.03), while total NO lower (p=0.0001), in the 26 patients with a BMI >28 kg/m 2 (33.4±0.7 kg/m 2 ) than in the non-obese ones (BMI=24.8±0.6 kg/m 2 ). These latter showed similar endothelial adhesin, ET-1 and NO levels than controls. Age, race, gender, blood pressure, albumin excretion and all metabolic variables with the exclusion of BMI did not predict endothelial factor levels. Hypertensive (i.e. blood pressure >140/90 mmHg) and normotensive diabetic patients had similar levels of circulating adhesins, ET-1 and NO. AC was followed by a significant reduction of plasma E-selectin (p=0.04) and HbA 1c levels (-2.2%, 95% CI 1.5 to 2.9%, p=0.0001). E-selectin decrements correlated with HbA 1c changes after 20 weeks in AC (r=0.42, p=0.01). In conclusion,E-selectin reduction after AC suggests metabolic control may influence endothelial activation in type II diabetics. However, multivariate analysis showed that only obesity influenced the whole endothelium. Surprisingly, neither blood pressure nor other well-recognized cardiovascular risk factors influenced endothelial adhesins, ET-1 and NO production. Thus, central obesity is the main determinant of endothelial activation in type II diabetics.

scholarly journals Frequency of metabolic syndrome in patients with newly diagnosed Type II Diabetes at DOW University Hospital, Karachi-Pakistan.

2021 ◽  
Vol 28 (11) ◽  
pp. 1546-1551
Author(s):  
Muhammad Umar Khan ◽  
Akhtar Ali Baloch ◽  
Muhammad Arsalan ◽  
Syed Muhammad Adnan
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Type Ii Diabetes ◽  
University Hospital ◽  
Diabetic Patients ◽  
Type Ii ◽  
Newly Diagnosed ◽  
Cross Sectional ◽  
The Mean

Objectives: To determine the prevalence of metabolic syndrome in patients with newly diagnosed type 2. Study Design: Descriptive Cross Sectional study. Setting: Dow University Hospital. Period: October 2018 to January 2019. Material & Methods: A total 342 patients prevalence of metabolic syndrome in patients with newly diagnosed type II diabetes at Dow University Hospital, Karachi, Pakistan. Data was collected through a questionnaire which is designed to record the age, gender, BMI, FBS, Waist circumference, blood pressure, HDL and triglyceride level of newly diagnosed of diabetic patients. Frequency and percentages were calculated for these variables. SPSS version 21 was used to analyze the overall results. Results: A total of 342 new diagnosed diabetic were included in this study. 189 (55.26%) were males and 153 (44.74%) were females. The mean + SD of age was 48.21±9.28 years. The mean + SD of FBS was about 192±43 mg/dl with ranges from 98 to 482 mg/dl. The mean + SD of Serum TG was about 243±152 mg/dl with ranges from 189 to 325 mg/dl. The mean + SD HDL was about 38.9±9.23 mg/dl with ranges from 12 to 102 mg/dl. The mean + SD of waist circumference was about 110.5±11.90 cm. The mean + SD systolic & diastolic blood pressure was about 150 + 8.23 & 98 + 11.28 respectively. The mean + SD of BMI was 29.23+ 11.23. Metabolic syndrome was diagnosed in 252 (73.68%) in newly diabetic patients. Conclusion: Metabolic syndromes were highly associated with newly diagnosed type II diabetes patients.

scholarly journals Depression In Type 2 Diabetes Mellitus : A Cross-Sectional Study In Tertiary Care Teaching Hospital In India

2018 ◽  
Vol 2 (1) ◽  
pp. 24-28 ◽  
Author(s):  
P. Varma ◽  
R. Kant ◽  
P.P. Mishra
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Type Ii ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prevalence Of Depression

Introduction: In our country, number of patients of diabetes is increasing every year, so of depression. The emotional consequences of diabetes have been scrutinized in a number of studies and varying results about the association of depression with type 2 diabetes mellitus have been found. While depression may contribute to poor diabetes-related outcomes, diabetes and its complications may also contribute to poor depression outcomes. Both conditions may have common underlying biological and behavioural mechanisms, such as genetic susceptibility and common pathophysiological mechanism. AIM-To assess the prevalence and the factors associated with depression among the patients with type II diabetes mellitus.Materials and Methods: Single centre, descriptive, cross-sectional study conducted in tertiary care teaching hospital in India for a period of 8 months. 586 type II diabetes patients aged between 30 and 70 years were included. Patients taking mood elevator drugs, suffering from mental illness, gestational diabetes and type 1 diabetes were excluded from the study. Physicians Health Questionnare-9 (PHQ-9) with a score of ≥5 was used to make the diagnosis of depression.Results: Prevalence of depression among the diabetic patients found to be 49.48%. Many factors have been found to be associated with increased prevalence of depression among diabetic patients such as age, female gender, house wife, high BMI, diabetes duration, diabetes related complications, comorbid conditions and poor glycaemic control with poor follow-up.Conclusion: By managing both depression and diabetes concurrently, better outcome in patients and increase in overall quality of life can be achieved. Early detection and treatment of depression by effectively screening all diabetic patients for depression would help to bring down the severity of depression among these patients.Jour of Diab and Endo Assoc of Nepal 2018; 2 (1): 24-28

scholarly journals Frequency of dyslipidemia in patients with type ii diabetes mellitus presenting in DHQ Teaching Hospital, Sahiwal.

2020 ◽  
Vol 27 (07) ◽  
pp. 1433-1437
Author(s):  
Abbas Humayun ◽  
Khalil Ahmad ◽  
Rana Aamir Diwan ◽  
Muhammad Saiful Malook
Keyword(s):  
Diabetes Mellitus ◽  
Teaching Hospital ◽  
Type Ii Diabetes ◽  
Blood Lipid ◽  
Diabetic Patients ◽  
Type Ii ◽  
Pathology Laboratory ◽  
Cross Sectional ◽  
Screening Programs

Dyslipidemia is major risk factor for cardiovascular disease in diabetes mellitus (DM). Early detection and treatment of dyslipidemia in type 2 DM can prevent the risk for atherosclerosis. Objectives: To determine the frequency of dyslipidemia in patients with type 2 diabetes mellitus presenting in DHQ Teaching Hospital, Sahiwal for routine check-up. Study Design: Cross Sectional, Observational, Descriptive study. Setting: Medical Unit 1, DHQ Teaching Hospital, Sahiwal, Pakistan. Period: 05-05-2018 to 05-11-2018. Material & Methods: Total 180 patients fulfilling selection criteria were enrolled in the study. Blood samples were obtained and sent to the Pathology Laboratory of the hospital for assessment of lipid profile. Reports were assessed and if cholesterol>200mg/dl and triglyceride>150mg/dl, then dyslipidemia was labeled. All this information was recorded on pro-formas. Results: In this study dyslipidemia was diagnosed in 81(45%) patients. Frequency of dyslipidemia was higher in age group 51-60 years (44.4%) as well as among female patients (56.8%). Overweight patients and patients with normal BMI had the highest frequency of dyslipidemia. Conclusion: the results of this study showed high frequency of dyslipidemia among type II diabetic patients. Type II diabetes is very much common in our population so there is a need to design screening programs in which blood lipid levels screening should be monitored on regular intervals to rule out dyslipidemia timely and for effective and proper management with statin therapy.

scholarly journals Hypertension and Related Risk Factors Among Clients on Combined Antiretroviral Therapy in Nigeria

2018 ◽  
Vol 21 (1) ◽  
pp. 35-41
Author(s):  
Shakirat I Bello ◽  
Winified A Ojieabu
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Antiretroviral Therapy ◽  
Pharmaceutical Journal ◽  
Cross Sectional Study ◽  
Blood Pressure Monitor ◽  
Pressure Monitor ◽  
Cross Sectional ◽  
Infected People ◽  
Combined Antiretroviral Therapy

Hypertension is a major challenge in human immunodeficiency virus (HIV) infected people globally. A prospective, cross-sectional study comprising two hundred and eighteen HIV-infected patients was conducted in Antiretroviral Therapy Clinic of General Hospital, Offa between November 2015 and December, 2016. Patients’ blood pressure was evaluated using Omron automated blood pressure monitor following standard procedures. Dual weight and height balance was utilized to measure the weight and height of the subjects. Hypertension incidence among patients receiving combined antiretroviral therapy (cART) was 34%, while those that were yet to start cART was 9.6 %. In HIVinfected women on cART, occurrence of hypertension was high (75.5%) as compared to men (24.5%). The hypertension pervasiveness in HIV-infected patients on cART was 75.5% in women and 24.5% in men. Risk factors that were markedly linked with hypertension among patients on cART include body mass index (OR: 3.29,95% CI:1.21-2.27; p< 0.050), sedentary lifestyle (OR: 1.63, 95% CI:1.20-5.38; p < 0.043), age (OR: 2.17, 95% CI: 1.22-2.33; p< 0.004) and gender (OR: 1.63, 95% CI: 0.85-2.41; p < 0.037). Patients on cART were found to have higher hypertension prevalence than cART-naive. The cART, however, is not a risk factor for hypertension.Bangladesh Pharmaceutical Journal 21(1): 35-41, 2018

scholarly journals Associations of Demographic, Clinical and Laboratory Profiles of Patients with type II Diabetes Mellitus with its Microvascular Complications in Bangladesh

2020 ◽  
Author(s):  
Mamunur Rashid ◽  
Abdul Mukit ◽  
Khawza Iftekhar Uddin Ahmed ◽  
Raqibul Mostafa ◽  
Sharmin Parveen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Microvascular Complications ◽  
Significant Risk ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Cardiac Autonomic Neuropathy ◽  
Diabetic Patients ◽  
Type Ii ◽  
Cross Sectional

Abstract Objective: The aim of this study was to investigate the associations of makers from demographic, clinical, and laboratory profiles with microvascular complications in a cohort of type II diabetic population in Bangladesh. Methods: In this cross-sectional study 103 participants [47 Men and 56 Women; Age 40~70 years] having type II diabetes for more than 10 years were randomly recruited during their routine visits to a major Diabetic Hospital in Dhaka, Bangladesh. The associations of prevalence of microvascular complications [Cardiac Autonomic Neuropathy(CAN), Diabetic Peripheral Neuropathy(DPN), Diabetic Nephropathy(Nep), Diabetic Retinopathy(Ret)] with demographic, clinical, and laboratory profiles were assessed by multivariate logistic regression (p<0.05 and Odds ratio (OR)> 1.0). Results: The prevalence rates of CAN, DPN, Ret and Nep were 68%, 43.69%, 6.8%, and 4.8% respectively. The overall prevalence of diabetic-associated microvascular complication is 94.36% in this cohort of diabetic patients. BMI (p=0.0330, OR=1.90) and HbA1c (p=0.0535, OR=3.08) were found to be the most significant risk factors in the development of all microvascular complications. However, HbA1c for CAN; HbA1c, Microalbuminuria and Urinary creatinine for DPN; years of Diabetes, Systolic blood pressure and albumin creatinine ratio for Nep, HbA1c and Microalbuminuria for Ret were found to be most significantly associated in this Diabetes patients’ cohort. Conclusion: The proportion of microvascular complications was found to be significantly high among patients with Type II diabetes mellitus in this cohort. Controlling HbA1c could help reduce all four types of complications. However, controlling microalbuminuria could prevent DPN and Ret. This emphasizes the need for screening and prevention program toward early, symptomless identification of type II diabetes microvascular complications.

scholarly journals High-intensity activity is more strongly associated with metabolic health in children compared to sedentary time: a cross-sectional study of the I.Family cohort

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Jonatan Fridolfsson ◽  
Christoph Buck ◽  
Monica Hunsberger ◽  
Joanna Baran ◽  
Fabio Lauria ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Body Mass Index ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
Cross Sectional ◽  
Intensity Physical Activity

Abstract Background Physical activity (PA) during childhood is important for preventing future metabolic syndrome (MetS). To examine the relationship between PA and MetS in more detail, accurate measures of PA are needed. Previous studies have only utilized a small part of the information available from accelerometer measured PA. This study investigated the association between measured PA and MetS in children with a new method for data processing and analyses that enable more detailed interpretation of PA intensity level. Methods The association between PA pattern and risk factors related to MetS was investigated in a cross- sectional sample of children (n = 2592, mean age 10.9 years, 49.4% male) participating in the European multicenter I. Family study. The risk factors examined include body mass index, blood pressure, high-density lipoprotein cholesterol, insulin resistance and a combined risk factor score (MetS score). PA was measured by triaxial accelerometers and raw data was processed using the 10 Hz frequency extended method (FEM). The PA output was divided into an intensity spectrum and the association with MetS risk factors was analyzed by partial least squares regression. Results PA patterns differed between the European countries investigated, with Swedish children being most active and Italian children least active. Moderate intensity physical activity was associated with lower insulin resistance (R2 = 2.8%), while vigorous intensity physical activity was associated with lower body mass index (R2 = 3.6%), MetS score (R2 = 3.1%) and higher high-density lipoprotein cholesterol (R2 = 2.3%). PA of all intensities was associated with lower systolic- and diastolic blood pressure, although the associations were weaker than for the other risk factors (R2 = 1.5% and R2 = 1.4%). However, the multivariate analysis implies that the entire PA pattern must be considered. The main difference in PA was observed between normal weight and overweight children. Conclusions The present study suggests a greater importance of more PA corresponding to an intensity of at least brisk walking with inclusion of high-intense exercise, rather than a limited time spent sedentary, in the association to metabolic health in children. The methods of data processing and statistical analysis enabled accurate analysis and interpretation of the health benefits of high intensity PA that have not been shown previously.

scholarly journals Use of physical activity and cardiorespiratory fitness in identifying cardiovascular risk factors in male brazilian adolescents

2016 ◽  
Vol 18 (6) ◽  
pp. 678
Author(s):  
Lilian Messias Sampaio Brito ◽  
Luis Paulo Gomes Mascarenhas ◽  
Deise Cristiane Moser ◽  
Ana Cláudia Kapp Titski ◽  
Monica Nunes Lima Cat ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Body Mass ◽  
Cardiorespiratory Fitness ◽  
High Blood Pressure ◽  
Abdominal Obesity ◽  
Age Groups ◽  
Cross Sectional ◽  
The Impact

DOI: http://dx.doi.org/10.5007/1980-0037.2016v18n6p678 The aim of this study was to investigate the impact of physical activity (PA) and cardiorespiratory fitness (CRF) levels on the prevalence of overweight and high blood pressure levels in adolescents. In this observational, cross-sectional study, 614 boys aged 10-14 years were assessed for height, body mass, body mass index (BMI), waist circumference (WC) and blood pressure (BP). CRF was assessed using a run test (Léger Test) and subjects were then grouped according to their CRF level. PA level was assessed through a questionnaire (The Three Day Physical Activity Recall) and classified into two groups, namely > 300 minutes of PA/week and < 300 minutes of PA/week. Maturational stage was evaluated according to the development of pubic hair (self-assessment) as proposed by Tanner. We used statistical descriptive analysis, univariate and multivariate analyses in the total participants and subjects were divided by age. Fifty percent of the sample performed < 300 minutes of PA/week and 67.6% had unsatisfactory CRF levels. There was a higher prevalence of unsatisfactory CRF levels among subjects with altered BMI (overweight), WC (abdominal obesity) or BP (high blood pressure) for all age groups. PA history, however, did not show any significance. A total of 31% of participants were overweight, 24.8% had abdominal obesity and 15.4% had increased BP. Unsatisfactory CRF levels were found to be a better predictor for the diagnosis of cardiovascular diseases (CV) risk factors than PA history, regardless of age group. 

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